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Assessing the Clinical Significance of Botanical Supplementation on Human Cytochrome P450 3A4 Activity: Comparison of Milk Thistle and Black Cohosh to rifampin and Clarithromycin

Gurley B, Hubbard MA, Williams DK, Thaden J, Tong Y, Gentry WB, Breen P, Carrier DJ, Cheboyina S. Assessing the Clinical Significance of Botanical Supplementation on Human Cytochrome P450 3A4 Activity: Comparison of Milk Thistle and Black Cohosh to rifampin and Clarithromycin. J Clin Pharmacol. 2006; 46:201-213.