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John Shaughnessy Jr

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentInternal Med, College of Medicine
DivisionInternal Med Hem-Onc
Address4104 Outpatient Circle
Mail Slot # 508
Little Rock AR 72205
Phone501-526-6990
ORCID ORCID Icon0000-0002-2017-6236 Additional info
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    Collapse Research 
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    1U54CA272691     (ZHAN, FENGHUANG)Sep 1, 2023 - Aug 31, 2027
    NIH/Nat. Cancer Institute - Pass Through: Baylor College of Medicine
    U54 - Administrative Core
    Role: Principal Investigator
    1U54CA272691-01A1     (ZHAN, FENGHUANG)Sep 1, 2023 - Aug 31, 2027
    NIH/Nat. Cancer Institute - Pass Through: Baylor College of Medicine
    U54 - Administrative Core
    Role: Principal Investigator
    1U54CA272691-02     (SHAUGHNESSY, JOHN)Sep 1, 2023 - Aug 31, 2027
    NIH/Nat. Cancer Institute - Pass Through: Baylor College of Medicine
    U54 - Bioinformatics Core
    Role: Principal Investigator
    R01CA115399     (TRICOT, GUIDO J.)Jul 13, 2006 - Apr 30, 2014
    NIH
    Gene expression profiling vs MRD assessment in Myeloma
    Role: Co-Investigator
    ZGEN TACI-Fc5 SRA     (SHAUGHNESSY JR, JOHN)May 25, 2005 - May 25, 2007
    ZymoGenetics, Inc
    Studying the role of APRIL and BAFF signaling in Myelomagenesis and its Therapy
    Role: Principal Investigator
    ZGENTACI-Fc5SRA     (SHAUGHNESSY JR, JOHN)May 25, 2005 - May 25, 2007
    ZymoGenetics, Inc
    Studying the role of APRIL and BAFF signaling in Myelomagenesis and its Therapy
    Role: Principal Investigator
    ARIA 15002 PcRA     (SHAUGHNESSY JR, JOHN)Nov 3, 2004 - Sep 8, 2006
    Millennium Pharmaceuticals, Inc.
    Preclinical Studies of the Mechanisms of Action of Velcade
    Role: Principal Investigator
    ARIA15002PcRA     (SHAUGHNESSY JR, JOHN)Nov 3, 2004 - Sep 8, 2006
    Millennium Pharmaceuticals, Inc.
    Preclinical Studies of the Mechanisms of Action of Velcade
    Role: Principal Investigator
    R33CA97513     (SHAUGHNESSY JR, JOHN)Jul 1, 2002 - Jun 30, 2005
    NIH/Nat. Cancer Institute
    Molecular Diagnosis and Prognosis of Multiple Myeloma
    Role: Principal Investigator
    R01CA093897     (YACCOBY, SHMUEL)Dec 1, 2001 - Nov 30, 2012
    NIH
    Myeloma-Microenvironment Interaction Dynamics
    Role: Co-Investigator
    U10CA32102     (SHAUGHNESSY JR, JOHN)Jan 1, 2001 - Dec 31, 2001
    NIH/Nat. Cancer Institute
    Developmental Funds Pilot of the Southwest Oncology Group-SWOG-01047
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Cheng Y, Sun F, Alapat DV, Wanchai V, Mery D, Siegel ER, Xu H, Johnson S, Guo W, Bailey C, Ashby C, Bauer MA, Hadidi SA, Schinke C, Thanendrarajan S, Zangari M, van Rhee F, Tricot G, Shaughnessy JD, Zhan F. Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages. Blood Cancer J. 2024 11 06; 14(1):194. PMID: 39505839.
      View in: PubMed
    2. Guo W, Zhan Y, Mery D, Siegel ER, Sun F, Cheng Y, Ashby TC, Zhang Z, Bailey C, Alapat DV, Peng H, Hadidi SA, Thanendrarajan S, Schinke C, Zangari M, van Rhee F, Tricot G, Shaughnessy JD, Zhan F. Prognostic value of ferritin in ASCT MM patients: integration with GEP models and ISS series systems. Blood Cancer J. 2024 02 14; 14(1):30. PMID: 38355688.
      View in: PubMed
    3. Sun F, Cheng Y, Ying J, Mery D, Al Hadidi S, Wanchai V, Siegel ER, Xu H, Gai D, Ashby TC, Bailey C, Chen JR, Schinke C, Thanendrarajan S, Zangari M, Janz S, Barlogie B, Van Rhee F, Tricot G, Shaughnessy JD, Zhan F. A gene signature can predict risk of MGUS progressing to multiple myeloma. J Hematol Oncol. 2023 06 29; 16(1):70. PMID: 37386588.
      View in: PubMed
    4. Xiong W, Wu X, Starnes S, Johnson SK, Haessler J, Wang S, Chen L, Barlogie B, Shaughnessy JD, Zhan F. An analysis of the clinical and biological significance of TP53 loss and the identification of potential novel transcriptional targets of TP53 in multiple myeloma. Blood. 2008.
    5. Zhan F, Colla S, Wu X, Chen B, Stewart JP, Kuehl WM, Barlogie B, Shaughnessy JD. CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through. Blood. 2007; 109(11):4995 - 5001.
    6. Santin AD, Zhan F, Bignotti E, Siegel ER, Cane S, Bellone S, Palmieri M, Anfossi S, Thomas M, Burnett A, Kay HH, Roman JJ, O'Brien TJ, Tian E, Cannon MJ, Shaughnessy J, Pecorelli S. Gene expression profiles of primary H. Virology. 2005; 331(2):269 - 291.
    7. Viera AJ, Hoag S, Shaughnessy J. Management of irritable bowel syndrome. Am Fam Physician. 2002; 66(10):1867 - 1874.
    8. Groetsch SM, Shaughnessy JM. Medical management of acute appendicitis: a case report. J Am Board Fam Pract. 2001; 14(3):225 - 226.
    9. Beecham EJ, Owens JD, Shaughnessy JD, Huppi K, Bohr VA, Mushinski JF. Decoupling of DNA excision repair and RNA transcription in translocation breaksite regions of plasmacytoma-susceptible BALB/cAnPt mice. Carcinogenesis. 1997; 18(4):687 - 694.
    10. Shaughnessy J. Role of the manager with the injured worker. Innovative idea. AAOHN J. 1996; 44(10):505 - 506.
    11. Janz S, Muller J, Shaughnessy J, Potter M. Detection of recombinations between c-myc and immunoglobulin switch alpha in murine plasma cell tumors and preneoplastic lesions by polymerase chain reaction. Proc Natl Acad Sci U S A. 1993; 90(15):7361 - 7365.
    12. Shaughnessy J. Preventing slips, trips, and falls in the workplace. AAOHN J. 1993; 41(6):304 - 305.
    13. Huppi K, Siwarski D, Shaughnessy J, Klemsz MJ, Shirakata M, Maki R, Sakano H. Genes associated with immunoglobulin V(D)J recombination are linked on mouse chromosome 2 and human chromosome 11. Immunogenetics. 1993; 37(4):288 - 291.
    14. Shaughnessy JL. Legislative assistant spends day with public health nurses. Fla Nurse. 1992; 40(1):11, 13 - .
    15. Grammer LC, Shaughnessy MA, Shaughnessy JJ, Patterson R. Safety and immunogenicity of immunotherapy with accelerated dosage schedules of polymerized grass and ragweed in patients with dual inhalant sensitivity. J Allergy Clin Immunol. 1989; 83(4):750 - 756.
    16. Shaughnessy J, Mock B, Duncan R, Potter M, Banner C. A restriction fragment length polymorphism at murine Glud locus co-segregates with Rib-1, Es-10, and Tcra on chromosome 14. Nucleic Acids Res. 1989; 17(7):2881 - .
    17. Grammer LC, Schafer M, Bernstein D, Bernstein IL, Cogen F, Dolovich J, Schatz M, Zeiger R, Shaughnessy JJ, Gutt L, . Prevention of chymopapain anaphylaxis by screening chemonucleolysis candidates with cutaneous chymopapain testing. Clin Orthop Relat Res. 1988; (234):12 - 15.
    18. Shaughnessy J. Pre-retirement planning and the role of the occupational health nurse. AAOHN J. 1988; 36(2):70 - 77.
    19. Fidler JR, Zechmeister EB, Shaughnessy JJ. Memory for frequency of hearing popular songs. Am J Psychol. 1988; 101(1):31 - 49.
    20. Grammer LC, Schafer M, Bernstein D, Bernstein IL, Dolovich J, Schatz M, Zeiger R, Cogen F, Shaughnessy JJ, Chandler MJ, . Prevention of chymopapain anaphylaxis by screening chemonucleolysis candidates with cutaneous chymopapain testing. A preliminary report. Clin Orthop Relat Res. 1987; (221):202 - 206.
    21. Grammer LC, Shaughnessy MA, Shaughnessy JJ, Patterson R. Practices in cat and dog immunotherapy among allergists. N Engl Reg Allergy Proc. 1987; 8(4):253 - 258.
    22. Grammer LC, Shaughnessy MA, Finkle SM, Shaughnessy JJ, Patterson R. A double-blind placebo-controlled trial of polymerized whole grass administered in an accelerated dosage schedule for immunotherapy of grass pollinosis. J Allergy Clin Immunol. 1986; 78(6):1180 - 1184.
    23. Neely CA, Truby SR, Shaughnessy JA, Barker ER, Burkhardt MA, Nagai-Jacobson MG, Snodgrass FG, Youngblood J. Professional role synthesis for nursing faculty: a redefinition of faculty practice. J Nurs Educ. 1986; 25(8):345 - 348.
    24. Grammer LC, Shaughnessy MA, Finkle SM, Shaughnessy JJ, Patterson R. Safety and immunogenicity of immunotherapy with polymerized tree, grass, and ragweed in patients with multiple inhalant sensitivities. J Allergy Clin Immunol. 1986; 77(1 Pt 1):53 - 58.
    25. Grammer LC, Shaughnessy MA, Shaughnessy JJ, Silvestri L, Patterson R. Allergenicity, immunogenicity, and safety of immunotherapy with various molecular weight ranges of polymerized ragweed. J Allergy Clin Immunol. 1985; 76(2 Pt 1):195 - 200.
    26. Grammer LC, Shaughnessy MA, Shaughnessy JJ, Patterson R. Brief report: evaluation of polymerized ragweed extracts by intradermal end point titration, RAST inhibition, and parallel line bioassay. J Allergy Clin Immunol. 1985; 76(1):123 - 127.
    27. Grammer LC, Shaughnessey MA, Shaughnessy JJ, Patterson R. Asthma as a variable in a study of immunotherapy for allergic rhinitis. J Allergy Clin Immunol. 1984; 73(5 Pt 1):557 - 560.
    28. Grammer LC, Shaughnessy MA, Suszko IM, Shaughnessy JJ, Patterson R. Persistence of efficacy after a brief course of polymerized ragweed allergen: a controlled study. J Allergy Clin Immunol. 1984; 73(4):484 - 489.
    29. Grammer LC, Shaughnessy MA, Suszko IM, Shaughnessy JJ, Patterson R. A double-blind histamine placebo-controlled trial of polymerized whole grass for immunotherapy of grass allergy. J Allergy Clin Immunol. 1983; 72(5 Pt 1):448 - 453.
    30. Terhune JA, Shaughnessy J. Health skills for life. Health Educ. 1983; 14(5):27 - 31.
    31. Shaughnessy JC. Central service catalog aids communication with nursing. HPN Hosp Purch News. 1982; 6(4):10 - .
    32. Shaughnessy JP, Ferguson SJ, Harris DA, Radda GK. Interaction of mitochondrial adenosine triphosphatase with nucleotides and with glycerol [proceedings]. Biochem Soc Trans. 1977; 5(5):1539 - 1540.
    33. Henshaw ET, Shaughnessy JT. The use of a scintillation counter to measure diagnostic X-ray tube kilovoltage, radiation exposure rates and contamination by low energy gamma emitters. Phys Med Biol. 1972; 17(4):577 - 583.
    34. JURY B, SHAUGHNESSY JE. DIPLOMA PROGRAMS PROFIT THROUGH SHARING. Nurs Outlook. 1964; 12:50 - 51.
    35. Shaughnessy J, Huppi, K., Mushinski, J.E. and Potter, M.. Springer-Verlag. Moloney Murine Leukemia Virus Integration 1060 Base Pairs 5' of c-Myc Exon 1 in a Plasmacytoma without a Chromosomal Translocation. Vol. 166 .
    36. Shaughnessy jr. J. Current Topics in Microbiology and Immunology, Mechanisms in B-Cell Neoplasia. Chromosomal translocations t(12;15) are an early event in murine plasmacytomagenesis. pp. 303-309.
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