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C. Lowry Barnes

TitleDepartment Chairperson
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentOrthopaedics Surgery, College of Medicine
Address4104 Outpatient Circle
Mail Slot # 531
Little Rock AR 72205
Phone501-614-2675
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    Collapse Overview 
    Collapse overview
    C. Lowry Barnes, MD, completed fellowship training in total joint replacement from Harvard Medical School and from Brigham and Women’s Hospital in Boston, Massachusetts. In 2000, Dr. Barnes was named the Arthritis Foundation Person of the Year. In 2006, Dr. Barnes was awarded a John Insall fellowship and joined three surgeons from Belgium, Japan, and Johns Hopkins lecturing, learning and exchanging ideas about total knee replacements in the United States and Canada. He is a teacher and researcher as well as a surgeon.

    Dr. Barnes has a special interest in surgery of the hip and knee and is an active member of the Association of Hip and Knee Surgeries. He lectures nationally and internationally on total joint replacement surgery and continues to do research related to the hip and knee through HipKnee Arkansas Foundation. He is currently consulting with Wright Medical and is helping to design new hip and knee replacements. He is the chair of Department of Orthopaedics at UAMS, and is currently president of Arkansas Orthopaedic Association. He has previously served as president of Southern Orthopaedic Association and Society for Arthritic Joint Surgery. He is named in “Best Doctors” and “Top Doctors in Orthopaedics,” and is consistently named as one of the top orthopaedic surgeons in Arkansas.


    Collapse Research Funds 
    Collapse research activities
    AVA-PST-320     (BARNES, C. LOWRY)Oct 15, 2018
    Dova Pharmaceuticals, Inc.
    An Open-Label Study to Evaluate the Efficacy and Safety of Avatrombopag for the Treatment of Subjects with Thrombocytopenia Scheduled for a Surgical Procedure
    Role: Principal Investigator
    214475     (BARNES, C. LOWRY)Mar 27, 2017
    Mayo Clinic
    Manipulation Under Anesthesia (MUA) to Treat Postoperative Stiffness after Total Knee Arthroplasty: A Multicenter Randomized Clinical Trial 205480
    Role: Principal Investigator
    PCS-1402-09328     (BARNES, C. LOWRY)Mar 1, 2016 - Feb 29, 2020
    Patient-Centered Outcomes Research Institute - Pass Through: Medical University of South Carolina
    Comparative Effectiveness of Pulmonary Embolism Prevention after Hip and Knee Replacement (PEPPER): Balancing Safety and Effectiveness
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
    List All   |   Timeline
    1. Stambough JB, Edwards PK, Mannen EM, Barnes CL, Mears SC. Flexion Instability After Total Knee Arthroplasty. J Am Acad Orthop Surg. 2019 Sep 01; 27(17):642-651. PMID: 30676514.
      View in: PubMed
    2. Hadden K, Martin R, Prince L, Barnes CL. Patient Health Literacy and Diabetic Foot Amputations. J Foot Ankle Surg. 2019 Sep; 58(5):877-879. PMID: 31474400.
      View in: PubMed
    3. Severin AC, Tackett SA, Barnes CL, Mannen EM. Three-dimensional kinematics in healthy older adult males during golf swings. Sports Biomech. 2019 Aug 27; 1-14. PMID: 31453740.
      View in: PubMed
    4. Severin AC, Gean RP, Barnes SG, Queen R, Butler RJ, Martin R, Barnes CL, Mannen EM. Effects of a corrective heel lift with an orthopaedic walking boot on joint mechanics and symmetry during gait. Gait Posture. 2019 09; 73:233-238. PMID: 31376749.
      View in: PubMed
    5. Wang J, Siddicky SF, Oliver TE, Dohm MP, Barnes CL, Mannen EM. Biomechanical Changes Following Knee Arthroplasty During Sit-To-Stand Transfers: Systematic Review. J Arthroplasty. 2019 Oct; 34(10):2494-2501. PMID: 31186182.
      View in: PubMed
    6. Stambough JB, Bloom GB, Edwards PK, Mehaffey GR, Barnes CL, Mears SC. Rapid Recovery After Total Joint Arthroplasty Using General Anesthesia. J Arthroplasty. 2019 Sep; 34(9):1889-1896. PMID: 31202638.
      View in: PubMed
    7. Edwards PK, Milles JL, Stambough JB, Barnes CL, Mears SC. Inpatient versus Outpatient Total Knee Arthroplasty. J Knee Surg. 2019 Aug; 32(8):730-735. PMID: 30921822.
      View in: PubMed
    8. Meeker DG, Cooper KB, Renard RL, Mears SC, Smeltzer MS, Barnes CL. Comparative Study of Antibiotic Elution Profiles From Alternative Formulations of Polymethylmethacrylate Bone Cement. J Arthroplasty. 2019 Jul; 34(7):1458-1461. PMID: 30935799.
      View in: PubMed
    9. Kee JR, Edwards PK, Barnes CL, Foster SE, Mears SC. After-Hours Calls in a Joint Replacement Practice. J Arthroplasty. 2019 Jul; 34(7):1303-1306. PMID: 30956045.
      View in: PubMed
    10. Edwards PK, Mears SC, Stambough JB, Foster SE, Barnes CL. Response to Letter to the Editor on "Choices, Compromises, and Controversies in Total Knee and Total Hip Arthroplasty Modifiable Risk Factors: What You Need to Know". J Arthroplasty. 2019 05; 34(5):1039. PMID: 30853156.
      View in: PubMed
    11. Severin AC, Barnes SG, Tackett SA, Barnes CL, Mannen EM. The required number of trials for biomechanical analysis of a golf swing. Sports Biomech. 2019 Jan 30; 1-9. PMID: 30698499.
      View in: PubMed
    12. Wilkinson J, Edwards PK, Levine M, Barnes CL. New Failure Mechanism of Acetabular Constrained Liner: A Case Report. J Surg Orthop Adv. 2019; 28(1):68-73. PMID: 31074741.
      View in: PubMed
    13. Hereford TE, Cryar KA, Edwards PK, Siegel ER, Barnes CL, Mears SC. Patients With Hip or Knee Arthritis Underreport Narcotic Usage. J Arthroplasty. 2018 10; 33(10):3113-3117. PMID: 29909957.
      View in: PubMed
    14. Hadden KB, Prince LY, Bushmiaer MK, Watson JC, Barnes CL. Health literacy and surgery expectations in total hip and knee arthroplasty patients. Patient Educ Couns. 2018 10; 101(10):1823-1827. PMID: 29880403.
      View in: PubMed
    15. Cryar KA, Hereford T, Edwards PK, Siegel E, Barnes CL, Mears SC. Preoperative Smoking and Narcotic, Benzodiazepine, and Tramadol Use are Risk Factors for Narcotic Use After Hip and Knee Arthroplasty. J Arthroplasty. 2018 09; 33(9):2774-2779. PMID: 29705679.
      View in: PubMed
    16. Hadden K, Prince LY, Barnes CL. Health Literacy Demands of Patient-Reported Evaluation Tools in Orthopedics: A Mixed-Methods Case Study. Qual Manag Health Care. 2018 Apr/Jun; 27(2):98-103. PMID: 29596271.
      View in: PubMed
    17. Edwards PK, Kee JR, Mears SC, Barnes CL. Erratum to "Is Rapid Recovery Hip and Knee Replacement Possible and Safe in the Octogenarian Patient?" [Journal of Arthroplasty 33 (2018) 316-319]. J Arthroplasty. 2018 06; 33(6):1985. PMID: 29534835.
      View in: PubMed
    18. Edwards PK, Mears SC, Stambough JB, Foster SE, Barnes CL. Choices, Compromises, and Controversies in Total Knee and Total Hip Arthroplasty Modifiable Risk Factors: What You Need to Know. J Arthroplasty. 2018 10; 33(10):3101-3106. PMID: 29573920.
      View in: PubMed
    19. Mears SC, Wilson MR, Mannen EM, Tackett SA, Barnes CL. Position of the Hip in Yoga. J Arthroplasty. 2018 07; 33(7):2306-2311. PMID: 29573916.
      View in: PubMed
    20. Edwards PK, Mears SC, Barnes CL. Preoperative Care of the TKA Patient. J Knee Surg. 2018 Aug; 31(7):618-624. PMID: 29475211.
      View in: PubMed
    21. Marcus RE, Barnes CL, Amendola A. Letter to the Editor: Editorial: Do Orthopaedic Surgeons Belong on the Sidelines at American Football Games? Clin Orthop Relat Res. 2018 01; 476(1):167-168. PMID: 29389762.
      View in: PubMed
    22. Edwards PK, Kee JR, Mears SC, Barnes CL. Is Rapid Recovery Hip and Knee Replacement Possible and Safe in the Octogenarian Patient? J Arthroplasty. 2018 02; 33(2):316-319. PMID: 29107492.
      View in: PubMed
    23. Shewale AR, Barnes CL, Fischbach LA, Ounpraseuth ST, Painter JT, Martin BC. Comparative Effectiveness of Intra-Articular Hyaluronic Acid and Corticosteroid Injections on the Time to Surgical Knee Procedures. J Arthroplasty. 2017 12; 32(12):3591-3597.e24. PMID: 28781020.
      View in: PubMed
    24. Kee JR, Mears SC, Edwards PK, Barnes CL. Modifiable Risk Factors Are Common in Early Revision Hip and Knee Arthroplasty. J Arthroplasty. 2017 12; 32(12):3689-3692. PMID: 28780223.
      View in: PubMed
    25. Shewale AR, Barnes CL, Fischbach LA, Ounpraseuth ST, Painter JT, Martin BC. Comparison of Low-, Moderate-, and High-Molecular-Weight Hyaluronic Acid Injections in Delaying Time to Knee Surgery. J Arthroplasty. 2017 10; 32(10):2952-2957.e21. PMID: 28606459.
      View in: PubMed
    26. Kee JR, Edwards PK, Barnes CL. Effect of Risk Acceptance for Bundled Care Payments on Clinical Outcomes in a High-Volume Total Joint Arthroplasty Practice After Implementation of a Standardized Clinical Pathway. J Arthroplasty. 2017 08; 32(8):2332-2338. PMID: 28433428.
      View in: PubMed
    27. Edwards PK, Mears SC, Barnes CL. BPCI: Everyone Wins, Including the Patient. J Arthroplasty. 2017 06; 32(6):1728-1731. PMID: 28389136.
      View in: PubMed
    28. Edwards PK, Jacobs CA, Hadden KB, Barnes CL. A Perioperative Patient Support System Was Unable to Mitigate the Risk of Hospital Readmission for Total Hip Arthroplasty Patients With High American Society of Anesthesiologists Grades. J Arthroplasty. 2017 04; 32(4):1100-1102. PMID: 27838015.
      View in: PubMed
    29. Park KJ, Menendez ME, Barnes CL. Perioperative Periprosthetic Fractures Associated With Primary Total Hip Arthroplasty. J Arthroplasty. 2017 03; 32(3):992-995. PMID: 27866949.
      View in: PubMed
    30. Couch CG, Menendez ME, Barnes CL. Perioperative Risk in Patients With Epilepsy Undergoing Total Joint Arthroplasty. J Arthroplasty. 2017 02; 32(2):537-540. PMID: 27720235.
      View in: PubMed
    31. Park KJ, Menendez ME, Mears SC, Barnes CL. Patients With Multiple Myeloma Have More Complications After Surgical Treatment of Hip Fracture. Geriatr Orthop Surg Rehabil. 2016 Sep; 7(3):158-62. PMID: 27551575.
      View in: PubMed
    32. Park KJ, Couch CG, Edwards PK, Siegel ER, Mears SC, Barnes CL. Tranexamic Acid Reduces Blood Transfusions in Revision Total Hip Arthroplasty. J Arthroplasty. 2016 12; 31(12):2850-2855.e1. PMID: 27426220.
      View in: PubMed
    33. Edwards PK, Hadden KB, Connelly JO, Barnes CL. Effect of Total Joint Arthroplasty Surgical Day of the Week on Length of Stay and Readmissions: A Clinical Pathway Approach. J Arthroplasty. 2016 12; 31(12):2726-2729. PMID: 27378632.
      View in: PubMed
    34. Kee JR, Smith RG, Barnes CL. Recognizing and Reducing the Risk of Opioid Misuse in Orthopaedic Practice. J Surg Orthop Adv. 2016 Winter; 25(4):238-243. PMID: 28244866.
      View in: PubMed
    35. O'Neal RM, Cryer KA, Edwards PK, Barnes CL, Mears SC. Narcotic Use: A Modifiable Risk Factor for Hip and Knee Arthroplasty. J Surg Orthop Adv. 2016 Winter; 25(4):227-233. PMID: 28244864.
      View in: PubMed
    36. Hadden KB, Prince LY, Barnes CL. Health Literacy and Opioid Use in Orthopaedic Patients. J Surg Orthop Adv. 2016 Winter; 25(4):234-237. PMID: 28244865.
      View in: PubMed
    37. Mears SC, Edwards PK, Barnes CL. How to Decrease Length of Hospital Stay After Total Knee Replacement. J Surg Orthop Adv. 2016; 25(1):2-7. PMID: 27082881.
      View in: PubMed
    38. Tait MA, Petrus C, Barnes CL. Southern Orthopaedic Association Abstract Publication Rate. J Surg Orthop Adv. 2016; 25(2):86-8. PMID: 27518291.
      View in: PubMed
    39. Park KJ, Bushmiaer M, Barnes CL. Bilateral adrenal hemorrhage in a total knee patient associated with enoxaparin usage. Arthroplast Today. 2015 Sep; 1(3):65-68. PMID: 28326373.
      View in: PubMed
    40. Edwards PK, Levine M, Cullinan K, Newbern G, Barnes CL. Avoiding readmissions-support systems required after discharge to continue rapid recovery? J Arthroplasty. 2015 Apr; 30(4):527-30. PMID: 25813402.
      View in: PubMed
    41. Rogers JM, Patel KV, Barnes CL. Design comparison: manipulation after total knee arthroplasty. J Surg Orthop Adv. 2015; 24(1):47-50. PMID: 25830263.
      View in: PubMed
    42. Heim EA, Grier AJ, Butler RJ, Bushmiaer M, Queen RM, Barnes CL. Use of Liposomal Bupivacaine Instead of an Epidural Can Improve Outcomes Following Total Knee Arthroplasty. J Surg Orthop Adv. 2015; 24(4):230-4. PMID: 26731386.
      View in: PubMed
    43. Shnaekel A, Hadden K, Barnes CL. Readability of Online Patient Educational Materials on Pain Management. J Surg Orthop Adv. 2015; 24(4):242-5. PMID: 26731388.
      View in: PubMed
    44. Tait MA, Dredge C, Barnes CL. Preoperative Patient Education for Hip and Knee Arthroplasty: Financial Benefit? J Surg Orthop Adv. 2015; 24(4):246-51. PMID: 26731389.
      View in: PubMed
    45. Connelly JO, Edwards PK, Mears SC, Barnes CL. Technique for Periarticular Local Infiltrative Anesthesia Delivery Using Liposomal Bupivacaine in Total Knee Arthroplasty. J Surg Orthop Adv. 2015; 24(4):263-6. PMID: 26731392.
      View in: PubMed
    46. Ciaccio CE, DiDonna A, Kennedy K, Barnes CS, Portnoy JM, Rosenwasser LJ. Secondhand tobacco smoke exposure in low-income children and its association with asthma. Allergy Asthma Proc. 2014 Nov-Dec; 35(6):462-6. PMID: 25584913.
      View in: PubMed
    47. Carpenter DP, Holmberg RR, Quartulli MJ, Barnes CL. Tibial plateau coverage in UKA: a comparison of patient specific and off-the-shelf implants. J Arthroplasty. 2014 Sep; 29(9):1694-8. PMID: 24768541.
      View in: PubMed
    48. Barnes CL, Vail TP, Takemoto SK. Where do knee revisions for infection, fracture, and other revisions get treated? J Arthroplasty. 2013 Mar; 28(3):423-8. PMID: 23433254.
      View in: PubMed
    49. Tait MA, Newbern GD, Alexander AS, Barnes CL. Rosenberg versus 20/10 views in osteoarthritic knees. J Knee Surg. 2013 Oct; 26(5):343-5. PMID: 23393052.
      View in: PubMed
    50. Barnes CL, Lincoln D, Wilson B. The EIUS unicompartmental knee design: early failure in elderly patients. J Knee Surg. 2013 Oct; 26(5):327-31. PMID: 23359397.
      View in: PubMed
    51. Barnes CL, Lincoln D, Wilson B, Bushmaier M. Knee manipulation after total knee arthroplasty: comparison of two implant designs. J Surg Orthop Adv. 2013; 22(2):157-9. PMID: 23628570.
      View in: PubMed
    52. Barnes CL, Blaha JD, DeBoer D, Stemniski P, Obert R, Carroll M. Assessment of a medial pivot total knee arthroplasty design in a cadaveric knee extension test model. J Arthroplasty. 2012 Sep; 27(8):1460-1468.e1. PMID: 22906409.
      View in: PubMed
    53. Barnes CL. Overview: the health care burden and financial costs of surgical site infections. Am J Orthop (Belle Mead NJ). 2011 Dec; 40(12 Suppl):2-5. PMID: 22268012.
      View in: PubMed
    54. Wilson B, Rankin H, Barnes CL. Long-term results of an unloader brace in patients with unicompartmental knee osteoarthritis. Orthopedics. 2011 Aug 08; 34(8):e334-7. PMID: 21815572.
      View in: PubMed
    55. Barnes CL, Sharma A, Blaha JD, Nambu SN, Carroll ME. Kneeling is safe for patients implanted with medial-pivot total knee arthroplasty designs. J Arthroplasty. 2011 Jun; 26(4):549-54. PMID: 20541359.
      View in: PubMed
    56. Barnes CL, Iwaki H, Minoda Y, Green JM, Obert RM. Analysis of sex and race and the size and shape of the distal femur using virtual surgery and archived computed tomography images. J Surg Orthop Adv. 2010; 19(4):200-8. PMID: 21244806.
      View in: PubMed
    57. Barnes CJ, Getelman MH, Snyder SJ. Results of arthroscopic revision anterior shoulder reconstruction. Am J Sports Med. 2009 Apr; 37(4):715-9. PMID: 19204368.
      View in: PubMed
    58. Barnes CL, DeBoer D, Corpe RS, Nambu S, Carroll M, Timmerman I. Wear performance of large-diameter differential-hardness hip bearings. J Arthroplasty. 2008 Sep; 23(6 Suppl 1):56-60. PMID: 18722303.
      View in: PubMed
    59. Barnes CL, Nambu S, Carroll M, Timmerman I, Svarczkopf T. Differential hardness bearings in hip arthroplasty. J Surg Orthop Adv. 2008; 17(1):40-4. PMID: 18284903.
      View in: PubMed
    60. Phillips BC, Barnes CL. MIIG HV case analysis. J Surg Orthop Adv. 2008; 17(1):58-61. PMID: 18284906.
      View in: PubMed
    61. Barnes CL, Mesko JW, Teeny SM, York SC. Treatment of medial compartment arthritis of the knee: a survey of the American Association of Hip and Knee Surgeons. J Arthroplasty. 2006 Oct; 21(7):950-6. PMID: 17027536.
      View in: PubMed
    62. Barnes CJ, Higgins LD, Major NM, Basamania CJ. Magnetic resonance imaging of the coracoclavicular ligaments: its role in defining pathoanatomy at the acromioclavicular joint. J Surg Orthop Adv. 2004; 13(2):69-75. PMID: 15281402.
      View in: PubMed
    63. Albritton MJ, Barnes CJ, Basamania CJ, Karas SG. Relationship of the axillary nerve to the proximal screws of a flexible humeral nail system: an anatomic study. J Orthop Trauma. 2003 Jul; 17(6):411-4. PMID: 12843725.
      View in: PubMed
    64. Barnes CJ, Pietrobon R, Higgins LD. Does the pulse examination in patients with traumatic knee dislocation predict a surgical arterial injury? A meta-analysis. J Trauma. 2002 Dec; 53(6):1109-14. PMID: 12478036.
      View in: PubMed
    65. Barnes CL, Cawley PW, Hederman B. Effect of CounterForce brace on symptomatic relief in a group of patients with symptomatic unicompartmental osteoarthritis: a prospective 2-year investigation. Am J Orthop (Belle Mead NJ). 2002 Jul; 31(7):396-401. PMID: 12180625.
      View in: PubMed
    66. Barnes CJ, Higgins LD. Vascular compromise after insertion of a retrograde femoral nail: case report and review of the literature. J Orthop Trauma. 2002 Mar; 16(3):201-4. PMID: 11880785.
      View in: PubMed
    67. Blasier RD, Barnes CL. Age as a prognostic factor in open tibial fractures in children. Clin Orthop Relat Res. 1996 Oct; (331):261-4. PMID: 8895648.
      View in: PubMed
    68. Berry DJ, Barnes CL, Scott RD, Cabanela ME, Poss R. Catastrophic failure of the polyethylene liner of uncemented acetabular components. J Bone Joint Surg Br. 1994 Jul; 76(4):575-8. PMID: 8027143.
      View in: PubMed
    69. Boyd AD, Thornhill TS, Barnes CL. Fractures adjacent to humeral prostheses. J Bone Joint Surg Am. 1992 Dec; 74(10):1498-504. PMID: 1469009.
      View in: PubMed
    70. Collins DN, Barnes CL, McCowan TC, Nelson CL, Carver DK, McAndrew MP, Ferris EJ. Vena caval filter use in orthopaedic trauma patients with recognized preoperative venous thromboembolic disease. J Orthop Trauma. 1992; 6(2):135-8. PMID: 1602331.
      View in: PubMed
    71. Barnes CL, Blasier RD, Dodge BM. Intravenous regional anesthesia: a safe and cost-effective outpatient anesthetic for upper extremity fracture treatment in children. J Pediatr Orthop. 1991 Nov-Dec; 11(6):717-20. PMID: 1960193.
      View in: PubMed
    72. Garvin KL, McCarthy RE, Barnes CL, Dodge BM. Pediatric pelvic ring fractures. J Pediatr Orthop. 1990 Sep-Oct; 10(5):577-82. PMID: 2394809.
      View in: PubMed
    73. Roberts TS, Nelson CL, Barnes CL, Ferris EJ, Holder JC, Boone DW. The preoperative prevalence and postoperative incidence of thromboembolism in patients with hip fractures treated with dextran prophylaxis. Clin Orthop Relat Res. 1990 Jun; (255):198-203. PMID: 1693325.
      View in: PubMed
    74. Gorman PW, Barnes CL, Fischer TJ, McAndrew MP, Moore MM. Soft-tissue reconstruction in severe lower extremity trauma. A review. Clin Orthop Relat Res. 1989 Jun; (243):57-64. PMID: 2656033.
      View in: PubMed
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