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William Gentry

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentAnesthesiology, College of Medicine
AddressB112 Biomedical Research I
325 S. Elm St.
Mail Slot # 515
Little Rock AR 72205
Phone501-320-7601
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    Other Positions
    TitleProfessor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentPharmacology and Toxicology, College of Medicine


    Collapse Research Funds 
    Collapse principal investigator/co-principal investigator research activities
    UL1TR003107     (JAMES, LAURA P)Jul 1, 2019 - Jun 30, 2024
    NIH/NCATS
    Expanding Translational Research in Arkansas
    Role: Co-Investigator
    U01DA045366     (GENTRY, WILLIAM)Oct 1, 2017 - Jul 31, 2020
    NIH/Nat. Inst. on Drug Abuse - Pass Through: InterveXion Therapeutics, LLC
    STAMPOUT: A Phase 2a Study of Antibody for Methamphetamine Outpatient Therapy’
    Role: Principal Investigator
    U01DA035511     (OWENS, SAMUEL)Jun 1, 2017 - May 31, 2019
    NIH/Nat. Inst. on Drug Abuse - Pass Through: InterveXion Therapeutics, LLC
    A Methamphetamine Conjugate Vaccine: From Manufacturing to IND - Continuation - Continuation
    Role: Co-Investigator
    U01DA037593     (GENTRY, WILLIAM)Sep 15, 2014 - Jun 30, 2018
    NIH/Nat. Inst. on Drug Abuse - Pass Through: InterveXion Therapeutics, LLC
    Transition to Human Phase 1b Trials: Nonclinical Studies of an Anti-METH mAb
    Role: Principal Investigator
    R21DA031837     (OLIVETO, ALISON)May 1, 2012 - Aug 31, 2015
    NIH/Nat. Inst. on Drug Abuse
    Impact of CYP2D6 Phenotype on Response to Methamphetamine in Humans
    Role: Co-Investigator
    R01DA031944     (GENTRY, WILLIAM)Jul 15, 2011 - Jun 30, 2015
    NIH/Nat. Inst. on Drug Abuse
    First Human Studies of a Chimeric Anti-Methamphetamine Monoclonal Antibody
    Role: Principal Investigator
    RC2DA028915     (GENTRY, WILLIAM)Oct 1, 2009 - Aug 20, 2012
    NIH/Nat. Inst. on Drug Abuse - Pass Through: InterveXion Therapeutics, LLC
    Chimeric anti-Methamphetamine Monoclonal Antibody for Treatment of METH Toxicity
    Role: Principal Investigator
    R01DA026916     (GENTRY, WILLIAM)Sep 1, 2009 - Jul 31, 2013
    NIH/Nat. Inst. on Drug Abuse
    Monoamine Antagonist Therapies for Methamphetamine Abuse
    Role: Principal Investigator
    U01DA023900     (OWENS, SAMUEL)Sep 30, 2007 - Aug 31, 2013
    NIH/Nat. Inst. on Drug Abuse
    Active Immunization for Treating Methamphetamine Abuse
    Role: Co-Investigator
    R42DA017596     (GENTRY, WILLIAM)Sep 10, 2004 - Oct 31, 2010
    NIH/Nat. Inst. on Drug Abuse - Pass Through: InterveXion Therapeutics, LLC
    Development of Plant Derived Antibodies for Drug Abuse
    Role: Principal Investigator
    K08DA00339     (GENTRY, WILLIAM)May 1, 2002 - Apr 30, 2004
    NIH/Nat. Inst. on Drug Abuse
    Mechanisms of Onset & Offset of Rapid Stimulant Effects
    Role: Principal Investigator
    R01DA011560     (OWENS, SAMUEL)Jan 5, 1998 - Mar 31, 2012
    NIH/Nat. Inst. on Drug Abuse
    Antibody-based Therapy for Methamphetamine Abuse
    Role: Co-Investigator
    R01DA010017     (OLIVETO, ALISON)Sep 30, 1997 - Nov 30, 2012
    NIH/Nat. Inst. on Drug Abuse
    Opioid Antagonist Discrimination: A Model of Withdrawal
    Role: Co-Investigator
    R01DA007610     (OWENS, SAMUEL)Mar 1, 1992 - Jun 30, 2012
    NIH/Nat. Inst. on Drug Abuse
    Immunotherapy for Drug Abuse
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Oliveto A, Mancino M, Sanders N, Cargile C, Guise JB, Bickel W, Gentry W Brooks. Effects of Prototypic Calcium Channel Blockers in Methadone-Maintained Humans Under a Naloxone Discrimination Procedure. Eur J Pharmacol. 2013.
    2. Walker BL, Vander Schilden JL, Gentry W Brooks. Intraarticular Analgesia Using a Meperidine-Local Anesthetic Combination in Arthroscopic Knee Procedures. Chirurgia Kolana, Atroskopia, Traumatologia Sportowa. 2013; 8(1):21-27.
    3. Hubbard JJ, Laurenzana EM, Williams DK, Gentry WB, Owens SM. The Fate and Function of Therapeutic Anti-addiction Monoclonal Antibodies. J Pharmacol Exp Ther. 2011; 336:414-22.
    4. White SJ, Laurenzana EM, Hendrickson HP, Gentry WB, Owens SM. Gestation time-dependent pharmacokinetics of intravenous (+)-methamphetamine and (+)-amphetamine in rats. Drug Metab Disp. 2011; 39:1718-26.
    5. Oliveto A, Gentry WB, Pruzinsky R, Gonsai K, Kosten TR, Martell B, Poling J. Behavioral effects of gamma-hydroxybutyrate in humans. Behav Pharmacol. 2010 Jul; 21(4):332-42. PMID: 20526195.
      View in: PubMed
    6. Oliveto A, Gentry WB, Pruzinsky R, Gonsai K, Kosten TR, Martell B, Poling J. Behavioral Effects of Gamma-Hydroxybutyrate (GHB) in Humans. Behavioral Pharmacology. 2010; 21:332-342.
    7. White SJ, Laurenzana EM, Gentry WB, Hendrickson HP, Williams DK, Ward KW, Owens SM. Vulnerability to (+)-methamphetamine effects and the relationship to drug disposition in pregnant rats during chronic infusion. Toxicol Sci. 2009 Sep; 111(1):27-36. PMID: 19520673.
      View in: PubMed
    8. Dunning D, Martin MP, Tickel JL, Gentry WB, Cowen P, Slenning BD. Preparedness and disaster response training for veterinary students: literature review and description of the North Carolina State University Credentialed Veterinary Responder Program. J Vet Med Educ. 2009; 36(3):317-30. PMID: 19861720.
      View in: PubMed
    9. Kumar P, Gentry WB. Ultrasound Guidance in Regional Anesthesia. J Anaesth Clin Pharmacol. 2007; 23(2):121-128.
    10. Gentry WB, Laurenzana EM, Williams DK, West JR, Berg RJ, Terlea T, Owens SM. Safety and Efficiency of an Anti-(+)-Methamphetamine Monoclonal IgG in the Protection against Cardiovascular and Central Nervous System Effects of (+)-Methamphetamine in Rats. International Immunopharmacology. 2006; 6:968-977.
    11. Gurley B, Hubbard MA, Williams DK, Thaden J, Tong Y, Gentry WB, Breen P, Carrier DJ, Cheboyina S. Assessing the Clinical Significance of Botanical Supplementation on Human Cytochrome P450 3A4 Activity: Comparison of Milk Thistle and Black Cohosh to rifampin and Clarithromycin. J Clin Pharmacol. 2006; 46:201-213.
    12. Pitas G, Laurenzana EM, Williams DK, Owens SM, Gentry WB. Anti-PCP Monoclonal Antibody Binding Capacity is not the Only Determinant of Effectiveness, Disproving the Concept that Antibody Capacity is easily Surmounted. Drug Metab Dispos. 2006; 34:906-912.
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