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Steven Post

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPathology, College of Medicine
Address609-2 Biomedical Research II
200 South Cedar
Mail Slot # 845
Little Rock AR 72202
Phone501-526-6046
ORCID ORCID Icon0000-0002-4711-1723 Additional info
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    Other Positions
    TitleProfessor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentPharmacology and Toxicology, College of Medicine


    Collapse Biography 
    Collapse Leadership and Administrative Roles
    Vice Chair of Research, Dept. of Pathology

    Director, Division of Experimental Pathology

    Associate Director of Shared Resources, Winthrop P. Rockefeller Cancer Institute

    Leader, Cancer Biology Program, Winthrop P. Rockefeller Cancer Institute

    Director, UAMS Tissue Biorepository and Procurement Service

    Director, Experimental Pathology Research Core

    Chair, UAMS Academic Conflict of Interest Committee

    Chair, University Research Committee


    Collapse Research 
    Collapse research overview
    The goal of our research is to better understand the key role that macrophages play in the development and progression of chronic inflammatory diseases including cardiovascular disease and cancer. Our studies indicate that a specific macrophage receptor, the class A macrophage scavenger receptor (SR-A), may differentially function to enhance or diminish inflammation. Our ongoing studies seek to provide mechanistic details regarding the functional interactions between SR-A and inflammatory signaling pathways. Results of these studies will advance understanding of the pathologic role of macrophages in cardiovascular disease and cancer, and may indicate novel therapeutic approaches targeting the inflammatory responses in these disease.

    Collapse research activities and funding
    R21CA280448     (POST, STEVEN R)Jan 1, 2024 - Dec 31, 2025
    NIH/Nat. Cancer Institute
    SR-A as a therapeutic target in breast cancer
    Role: Principal Investigator
    1R01HL162958     (Ding)Apr 1, 2022 - Jul 31, 2023
    NIH/Nat. Heart, Lung & Blood Institute
    Impact of hemodynamics on efferocytosis in endothelial cells
    Role Description: End with transfer of PI
    Role: Co-Investigator
    R01CA228166     (POST, STEVEN R)May 1, 2019 - Apr 30, 2025
    NIH/Nat. Cancer Institute
    Periodontal bacteria enhance oral KSHV pathogenesis and Kaposi's Sarcoma development in HIV + patients - Continuation
    Role: Principal Investigator
    R01CA228166     (POST, STEVEN R)May 1, 2019 - Apr 30, 2025
    NIH/Nat. Cancer Institute
    Periodontal bacteria enhance oral KSHV pathogenesis and Kaposi's Sarcoma development in HIV + patients - Continuation
    Role: Co-Investigator
    ABCRP FY19     (EOFF, ROBERT L)Feb 1, 2019 - Jun 30, 2021
    UAMS Executive Breast Committee
    No FP attached
    Role: Principal Investigator
    DEAP FY19     (POST, STEVEN R)Jan 1, 2019 - Dec 31, 2020
    UAMS Internal Research Awards
    No FP attached
    Role: Principal Investigator
    R21AI133160     (WARE, JERRY)May 25, 2017 - Apr 30, 2020
    NIH
    Leukocyte-platelet modulation of the systemic inflammatory response
    Role: Co-Principal Investigator
    17GRNT33410609     (POST, STEVEN R)Jan 1, 2017 - May 25, 2017
    American Heart Association
    Platelet-leukocyte regulation of inflammatory responses- Resubmission- Resubmission
    Role: Principal Investigator
    R21CA185691     (POST, STEVEN R)Dec 1, 2015 - Nov 30, 2018
    NIH/National Institutes of Health
    Fibroblast-macrophage interactions induce a tumor-promoting microenvironment
    Role: Principal Investigator
    R01HL089588     (POST, STEVEN R)Apr 1, 2008 - Mar 31, 2013
    NIH/Nat. Heart, Lung & Blood Institute
    Function and Regulation of SR-A in Atherosclerosis
    Role: Principal Investigator
    R01HL075241     (POST, STEVEN R)Dec 1, 2003 - Nov 30, 2009
    NIH/Nat. Heart, Lung & Blood Institute
    Regulation of Ras Signaling by Rlf in Hypertrophy
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse additional bibliographic sources
    The links below are provided by the researcher to provide access to external online bibliographies that they keep independently from the Profiles System.
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Ferdous KU, Tesfay MZ, Cios A, Shelton RS, Hartupee C, Urbaniak A, Chamcheu JC, Mavros MN, Giorgakis E, Mustafa B, Simoes CC, Miousse IR, Basnakian AG, Moaven O, Post SR, Cannon MJ, Kelly T, Nagalo BM. Enhancing Neoadjuvant Virotherapy's Effectiveness by Targeting Stroma to Improve Resectability in Pancreatic Cancer. Biomedicines. 2024 Jul 18; 12(7). PMID: 39062169.
      View in: PubMed
    2. Chen J, Lin Z, Fan J, Monzavi-Karbassi B, Kelly T, Post SR, Dai L, Qin Z. Identification of new microtubule small-molecule inhibitors and microtubule-associated genes against triple negative breast cancer. Am J Cancer Res. 2024; 14(4):1545-1560. PMID: 38726264.
      View in: PubMed
    3. Monzavi-Karbassi B, Kelly T, Post SR. The Tumor Microenvironment and Immune Response in Breast Cancer. Int J Mol Sci. 2024 Jan 11; 25(2). PMID: 38255987.
      View in: PubMed
    4. Marin LP, Presley JH, Noori K, McKinstry D, Dawson B, Sexton K, Peterson E, Harrington SE, Gardner JM, Nagalo BM, Montzavi-Karbassi B, Post SR, Nicholas RW, Kelly T. Partnership in Cancer Research (PCAR) Program Increases Medical Student Knowledge and Confidence to Perform Cancer Research. J Cancer Educ. 2024 Apr; 39(2):111-117. PMID: 37957501.
      View in: PubMed
    5. Chen J, Lin Z, Song J, Plaisance-Bonstaff K, James J, Mu S, Post SR, Dai L, Qin Z. Echinomycin as a promising therapeutic agent against KSHV-related malignancies. J Hematol Oncol. 2023 05 04; 16(1):48. PMID: 37143124.
      View in: PubMed
    6. Chen J, Song J, Plaisance-Bonstaff K, Mu S, Post SR, Dai L, Qin Z. Role of Histamine and Related Signaling in Kaposi's Sarcoma-Associated Herpesvirus Pathogenesis and Oncogenesis. Viruses. 2023 04 20; 15(4). PMID: 37112991.
      View in: PubMed
    7. Nounamo B, Jousheghany F, Siegel ER, Post SR, Kelly T, Ferrone S, Kieber-Emmons T, Monzavi-Karbassi B. VT68.2: An Antibody to Chondroitin Sulfate Proteoglycan 4 (CSPG4) Displays Reactivity against a Tumor-Associated Carbohydrate Antigen. Int J Mol Sci. 2023 Jan 28; 24(3). PMID: 36768830.
      View in: PubMed
    8. Nakamura N, Rogers P, Eggerson R, Post SR, Davis R. Translational Research for Identifying Potential Early-stage Prostate Cancer Biomarkers. Cancer Genomics Proteomics. 2023 Jan-Feb; 20(1):1-8. PMID: 36581341.
      View in: PubMed
    9. Chen J, Song J, James J, Plaisance-Bonstaff K, Post SR, Qin Z, Dai L. Activation of IL1 signaling molecules by Kaposi's sarcoma-associated herpesvirus. Front Cell Infect Microbiol. 2022; 12:1049624. PMID: 36457850.
      View in: PubMed
    10. Zhang Y, Gabere M, Taylor MA, Simoes CC, Dumbauld C, Barro O, Tesfay MZ, Graham AL, Ferdous KU, Savenka AV, Chamcheu JC, Washam CL, Alkam D, Gies A, Byrum SD, Conti M, Post SR, Kelly T, Borad MJ, Cannon MJ, Basnakian A, Nagalo BM. Repurposing live attenuated trivalent MMR vaccine as cost-effective cancer immunotherapy. Front Oncol. 2022; 12:1042250. PMID: 36457491.
      View in: PubMed
    11. Nagalo BM, Zhou Y, Loeuillard EJ, Dumbauld C, Barro O, Elliott NM, Baker AT, Arora M, Bogenberger JM, Meurice N, Petit J, Uson PLS, Aslam F, Raupach E, Gabere M, Basnakian A, Simoes CC, Cannon MJ, Post SR, Buetow K, Chamcheu JC, Barrett MT, Duda DG, Jacobs B, Vile R, Barry MA, Roberts LR, Ilyas S, Borad MJ. Characterization of Morreton virus as an oncolytic virotherapy platform for liver cancers. Hepatology. 2023 06 01; 77(6):1943-1957. PMID: 36052732.
      View in: PubMed
    12. Chen J, Song J, Dai L, Post SR, Qin Z. SARS-CoV-2 infection and lytic reactivation of herpesviruses: A potential threat in the?postpandemic era? J Med Virol. 2022 11; 94(11):5103-5111. PMID: 35819034.
      View in: PubMed
    13. Dai L, Lu YC, Chen J, Plaisance-Bonstaff K, Mu S, Forrest JC, Whitby D, Post SR, Qin Z. Oral Shedding of an Oncogenic Virus Alters the Oral Microbiome in HIV+ Patients. Front Microbiol. 2022; 13:882520. PMID: 35516440.
      View in: PubMed
    14. Chen J, Dai L, Kendrick S, Post SR, Qin Z. The Anti-COVID-19 Drug Remdesivir Promotes Oncogenic Herpesvirus Reactivation through Regulation of Intracellular Signaling Pathways. Antimicrob Agents Chemother. 2022 03 15; 66(3):e0239521. PMID: 35041508.
      View in: PubMed
    15. Chen J, Dai L, Barrett L, James J, Plaisance-Bonstaff K, Post SR, Qin Z. SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus. Commun Biol. 2021 06 03; 4(1):682. PMID: 34083759.
      View in: PubMed
    16. Del Valle L, Dai L, Lin HY, Lin Z, Chen J, Post SR, Qin Z. Role of EIF4G1 network in non-small cell lung cancers (NSCLC) cell survival and disease progression. J Cell Mol Med. 2021 03; 25(6):2795-2805. PMID: 33539648.
      View in: PubMed
    17. Chen J, Goyal N, Dai L, Lin Z, Del Valle L, Zabaleta J, Liu J, Post SR, Foroozesh M, Qin Z. Developing new ceramide analogs and identifying novel sphingolipid-controlled genes against a virus-associated lymphoma. Blood. 2020 11 05; 136(19):2175-2187. PMID: 32518949.
      View in: PubMed
    18. Chen J, Dai L, Barrett L, Post SR, Qin Z. SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus. bioRxiv. 2020 Oct 02. PMID: 33024968.
      View in: PubMed
    19. Dai L, Jung BG, Chen J, Samten B, Forrest JC, Post SR, Qin Z. The potential impacts of early secreted antigenic target of 6?kDa of Mycobacterium tuberculosis on KSHV-infected cells. J Med Virol. 2021 06; 93(6):4028-4032. PMID: 32648938.
      View in: PubMed
    20. Dai L, Barrett L, Plaisance-Bonstaff K, Post SR, Qin Z. Porphyromonas gingivalis coinfects with KSHV in oral cavities of HIV+ patients and induces viral lytic reactivation. J Med Virol. 2020 Dec; 92(12):3862-3867. PMID: 32436999.
      View in: PubMed
    21. Dai L, Qiao J, Yin J, Goldstein A, Lin HY, Post SR, Qin Z. Kaposi Sarcoma-Associated Herpesvirus and Staphylococcus aureus Coinfection in Oral Cavities of HIV-Positive Patients: A Unique Niche for Oncogenic Virus Lytic Reactivation. J Infect Dis. 2020 03 28; 221(8):1331-1341. PMID: 31111897.
      View in: PubMed
    22. Chen J, Dai L, Goldstein A, Zhang H, Tang W, Forrest JC, Post SR, Chen X, Qin Z. Identification of new antiviral agents against Kaposi's sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation. PLoS Pathog. 2019 12; 15(12):e1008156. PMID: 31790497.
      View in: PubMed
    23. Post GR, Yuan Y, Holthoff ER, Quick CM, Post SR. Identification of a novel monocytic phenotype in Classic Hodgkin Lymphoma tumor microenvironment. PLoS One. 2019; 14(11):e0224621. PMID: 31714922.
      View in: PubMed
    24. Murray GP, Post SR, Post GR. ABO blood group is a determinant of von Willebrand factor protein levels in human pulmonary endothelial cells. J Clin Pathol. 2020 Jun; 73(6):347-349. PMID: 31662441.
      View in: PubMed
    25. Chen J, Del Valle L, Lin HY, Plaisance-Bonstaff K, Forrest JC, Post SR, Qin Z. Expression of PD-1 and PD-Ls in Kaposi's sarcoma and regulation by oncogenic herpesvirus lytic reactivation. Virology. 2019 10; 536:16-19. PMID: 31394407.
      View in: PubMed
    26. Madan E, Pelham CJ, Nagane M, Parker TM, Canas-Marques R, Fazio K, Shaik K, Yuan Y, Henriques V, Galzerano A, Yamashita T, Pinto MAF, Palma AM, Camacho D, Vieira A, Soldini D, Nakshatri H, Post SR, Rhiner C, Yamashita H, Accardi D, Hansen LA, Carvalho C, Beltran AL, Kuppusamy P, Gogna R, Moreno E. Flower isoforms promote competitive growth in?cancer. Nature. 2019 08; 572(7768):260-264. PMID: 31341286.
      View in: PubMed
    27. Post SR, Post GR, Nikolic D, Owens R, Insuasti-Beltran G. Development of an unbiased, semi-automated approach for classifying plasma cell immunophenotype following multicolor flow cytometry of bone marrow aspirates. Cytometry B Clin Cytom. 2018 09; 94(5):602-610. PMID: 29573142.
      View in: PubMed
    28. Holthoff ER, Byrum SD, Mackintosh SG, Kelly T, Tackett AJ, Quick CM, Post SR. Vulvar squamous cell carcinoma aggressiveness is associated with differential expression of collagen and STAT1. Clin Proteomics. 2017; 14:40. PMID: 29225558.
      View in: PubMed
    29. Post GR, Guillory E, Wade CL, LeSourd SE, Post SR. Effect of Serum Immunoglobulins on Routine Coagulation Tests: A Comparison of Coagulation Analyzers using Mechanical and Optical Clot Detection. Ann Clin Lab Sci. 2017 Nov; 47(6):744-746. PMID: 29263049.
      View in: PubMed
    30. PrabhuDas MR, Baldwin CL, Bollyky PL, Bowdish DME, Drickamer K, Febbraio M, Herz J, Kobzik L, Krieger M, Loike J, McVicker B, Means TK, Moestrup SK, Post SR, Sawamura T, Silverstein S, Speth RC, Telfer JC, Thiele GM, Wang XY, Wright SD, El Khoury J. A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease. J Immunol. 2017 05 15; 198(10):3775-3789. PMID: 28483986.
      View in: PubMed
    31. Post GR, Bell RC, Rjoop A, Lobo RH, Yuan Y, Post SR. Diagnostic Utility of Interleukin-6 Expression by Immunohistochemistry in Differentiating Castleman Disease Subtypes and Reactive Lymphadenopathies. Ann Clin Lab Sci. 2016 Sep; 46(5):474-9. PMID: 27650613.
      View in: PubMed
    32. Holthoff ER, Spencer H, Kelly T, Post SR, Quick CM. Pathologic features of aggressive vulvar carcinoma are associated with epithelial-mesenchymal transition. Hum Pathol. 2016 10; 56:22-30. PMID: 27327194.
      View in: PubMed
    33. Mazur A, Holthoff E, Vadali S, Kelly T, Post SR. Cleavage of Type I Collagen by Fibroblast Activation Protein-a Enhances Class A Scavenger Receptor Mediated Macrophage Adhesion. PLoS One. 2016; 11(3):e0150287. PMID: 26934296.
      View in: PubMed
    34. Jeffus SK, Gehlot A, Holthoff E, Stone R, Spencer H, Kelly T, Post SR, Quick CM. A fibromyxoid stromal response is associated with an infiltrative tumor morphology, perineural invasion, and lymph node metastasis in squamous cell carcinoma of the vulva. Am J Surg Pathol. 2015 Sep; 39(9):1226-33. PMID: 26274029.
      View in: PubMed
    35. Holthoff ER, Jeffus SK, Gehlot A, Stone R, Erickson SW, Kelly T, Quick CM, Post SR. Perineural Invasion Is an Independent Pathologic Indicator of Recurrence in Vulvar Squamous Cell Carcinoma. Am J Surg Pathol. 2015 Aug; 39(8):1070-4. PMID: 25786085.
      View in: PubMed
    36. Jeffus SK, Joiner AK, Siegel ER, Massoll NA, Meena N, Chen C, Post SR, Bartter T. Rapid on-site evaluation of EBUS-TBNA specimens of lymph nodes: Comparative analysis and recommendations for standardization. Cancer Cytopathol. 2015 Jun; 123(6):362-72. PMID: 25931443.
      View in: PubMed
    37. Nikolic DM, Vadali S, He B, Ware J, Kelly T, Post SR. Prostaglandins produced during class A scavenger receptor-mediated macrophage adhesion differentially regulate cytokine production. J Leukoc Biol. 2015 May; 97(5):901-908. PMID: 25717147.
      View in: PubMed
    38. Ware J, Post SR. Platelets: balancing the septic triad. Blood. 2014 Dec 11; 124(25):3670-2. PMID: 25498452.
      View in: PubMed
    39. Vadali S, Post SR. Lipid rafts couple class A scavenger receptors to phospholipase A2 activation during macrophage adhesion. J Leukoc Biol. 2014 Nov; 96(5):873-81. PMID: 25070949.
      View in: PubMed
    40. Prabhudas M, Bowdish D, Drickamer K, Febbraio M, Herz J, Kobzik L, Krieger M, Loike J, Means TK, Moestrup SK, Post S, Sawamura T, Silverstein S, Wang XY, El Khoury J. Standardizing scavenger receptor nomenclature. J Immunol. 2014 Mar 01; 192(5):1997-2006. PMID: 24563502.
      View in: PubMed
    41. Corken A, Russell S, Dent J, Post SR, Ware J. Platelet glycoprotein Ib-IX as a regulator of systemic inflammation. Arterioscler Thromb Vasc Biol. 2014 May; 34(5):996-1001. PMID: 24504734.
      View in: PubMed
    42. Scotland RL, Allen L, Hennings LJ, Post GR, Post SR. The ral exchange factor rgl2 promotes cardiomyocyte survival and inhibits cardiac fibrosis. PLoS One. 2013; 8(9):e73599. PMID: 24069211.
      View in: PubMed
    43. Pandey S, Post SR, Alapat DV, Smock KJ, Post GR. Prolonged prothrombin time correlates with serum monoclonal protein concentration in patients with plasma cell dyscrasia. Int J Lab Hematol. 2013 Aug; 35(4):421-7. PMID: 23217011.
      View in: PubMed
    44. Nikolic D, Calderon L, Du L, Post SR. SR-A ligand and M-CSF dynamically regulate SR-A expression and function in primary macrophages via p38 MAPK activation. BMC Immunol. 2011 Jul 07; 12:37. PMID: 21736734.
      View in: PubMed
    45. Cholewa J, Nikolic D, Post SR. Regulation of class A scavenger receptor-mediated cell adhesion and surface localization by PI3K: identification of a regulatory cytoplasmic motif. J Leukoc Biol. 2010 Mar; 87(3):443-9. PMID: 19952357.
      View in: PubMed
    46. Nikolic DM, Gong MC, Turk J, Post SR. Class A scavenger receptor-mediated macrophage adhesion requires coupling of calcium-independent phospholipase A(2) and 12/15-lipoxygenase to Rac and Cdc42 activation. J Biol Chem. 2007 Nov 16; 282(46):33405-33411. PMID: 17873277.
      View in: PubMed
    47. Nikolic DM, Cholewa J, Gass C, Gong MC, Post SR. Class A scavenger receptor-mediated cell adhesion requires the sequential activation of Lyn and PI3-kinase. Am J Physiol Cell Physiol. 2007 Apr; 292(4):C1450-8. PMID: 17192284.
      View in: PubMed
    48. Lin YL, de Villiers WJS, Garvy B, Post SR, Nagy TR, Safadi FF, Faugere MC, Wang G, Malluche HH, Williams JP. The effect of class a scavenger receptor deficiency in bone. J Biol Chem. 2007 Feb 16; 282(7):4653-4660. PMID: 17166840.
      View in: PubMed
    49. Shetty S, Eckhardt ER, Post SR, van der Westhuyzen DR. Phosphatidylinositol-3-kinase regulates scavenger receptor class B type I subcellular localization and selective lipid uptake in hepatocytes. Arterioscler Thromb Vasc Biol. 2006 Sep; 26(9):2125-31. PMID: 16794223.
      View in: PubMed
    50. Xie Z, Su W, Guo Z, Pang H, Post SR, Gong MC. Up-regulation of CPI-17 phosphorylation in diabetic vasculature and high glucose cultured vascular smooth muscle cells. Cardiovasc Res. 2006 Feb 01; 69(2):491-501. PMID: 16336954.
      View in: PubMed
    51. Berwin B, Delneste Y, Lovingood RV, Post SR, Pizzo SV. SREC-I, a type F scavenger receptor, is an endocytic receptor for calreticulin. J Biol Chem. 2004 Dec 03; 279(49):51250-7. PMID: 15371419.
      View in: PubMed
    52. Du L, Post SR. Macrophage colony-stimulating factor differentially regulates low density lipoprotein and transferrin receptors. J Lipid Res. 2004 Sep; 45(9):1733-40. PMID: 15210846.
      View in: PubMed
    53. Berwin B, Hart JP, Rice S, Gass C, Pizzo SV, Post SR, Nicchitta CV. Scavenger receptor-A mediates gp96/GRP94 and calreticulin internalization by antigen-presenting cells. EMBO J. 2003 Nov 17; 22(22):6127-36. PMID: 14609958.
      View in: PubMed
    54. Kosswig N, Rice S, Daugherty A, Post SR. Class A scavenger receptor-mediated adhesion and internalization require distinct cytoplasmic domains. J Biol Chem. 2003 Sep 05; 278(36):34219-25. PMID: 12819208.
      View in: PubMed
    55. Post SR, Gass C, Rice S, Nikolic D, Crump H, Post GR. Class A scavenger receptors mediate cell adhesion via activation of G(i/o) and formation of focal adhesion complexes. J Lipid Res. 2002 Nov; 43(11):1829-36. PMID: 12401881.
      View in: PubMed
    56. Insel PA, Ostrom RS, Zambon AC, Hughes RJ, Balboa MA, Shehnaz D, Gregorian C, Torres B, Firestein BL, Xing M, Post SR. P2Y receptors of MDCK cells: epithelial cell regulation by extracellular nucleotides. Clin Exp Pharmacol Physiol. 2001 Apr; 28(4):351-4. PMID: 11339212.
      View in: PubMed
    57. Whitman SC, Daugherty A, Post SR. Macrophage colony-stimulating factor rapidly enhances beta-migrating very low density lipoprotein metabolism in macrophages through activation of a Gi/o protein signaling pathway. J Biol Chem. 2000 Nov 17; 275(46):35807-13. PMID: 10964909.
      View in: PubMed
    58. Ostrom RS, Post SR, Insel PA. Stoichiometry and compartmentation in G protein-coupled receptor signaling: implications for therapeutic interventions involving G(s). J Pharmacol Exp Ther. 2000 Aug; 294(2):407-12. PMID: 10900212.
      View in: PubMed
    59. Whitman SC, Daugherty A, Post SR. Regulation of acetylated low density lipoprotein uptake in macrophages by pertussis toxin-sensitive G proteins. J Lipid Res. 2000 May; 41(5):807-13. PMID: 10787441.
      View in: PubMed
    60. Post SR, Ostrom RS, Insel PA. Biochemical methods for detection and measurement of cyclic AMP and adenylyl cyclase activity. Methods Mol Biol. 2000; 126:363-74. PMID: 10685423.
      View in: PubMed
    61. Xing M, Post S, Ostrom RS, Samardzija M, Insel PA. Inhibition of phospholipase A2-mediated arachidonic acid release by cyclic AMP defines a negative feedback loop for P2Y receptor activation in Madin-Darby canine kidney D1 cells. J Biol Chem. 1999 Apr 09; 274(15):10035-8. PMID: 10187781.
      View in: PubMed
    62. Meyer M, Bluhm WF, He H, Post SR, Giordano FJ, Lew WY, Dillmann WH. Phospholamban-to-SERCA2 ratio controls the force-frequency relationship. Am J Physiol. 1999 03; 276(3):H779-85. PMID: 10070059.
      View in: PubMed
    63. Post SR, Hammond HK, Insel PA. Beta-adrenergic receptors and receptor signaling in heart failure. Annu Rev Pharmacol Toxicol. 1999; 39:343-60. PMID: 10331088.
      View in: PubMed
    64. Post SR, Rump LC, Zambon A, Hughes RJ, Buda MD, Jacobson JP, Kao CC, Insel PA. ATP activates cAMP production via multiple purinergic receptors in MDCK-D1 epithelial cells. Blockade of an autocrine/paracrine pathway to define receptor preference of an agonist. J Biol Chem. 1998 Sep 04; 273(36):23093-7. PMID: 9722536.
      View in: PubMed
    65. Gao M, Ping P, Post S, Insel PA, Tang R, Hammond HK. Increased expression of adenylylcyclase type VI proportionately increases beta-adrenergic receptor-stimulated production of cAMP in neonatal rat cardiac myocytes. Proc Natl Acad Sci U S A. 1998 Feb 03; 95(3):1038-43. PMID: 9448281.
      View in: PubMed
    66. Insel PA, Balboa MA, Mochizuki N, Post SR, Urasawa K, Xing M. Mechanisms for activation of multiple effectors by alpha 1-adrenergic receptors. Adv Pharmacol. 1998; 42:451-3. PMID: 9327936.
      View in: PubMed
    67. Insel PA, Firestein BL, Xing M, Post SR, Jacobson JP, Balboa MA, Hughes RJ. P2-purinoceptors utilize multiple signalling pathways in MDCK-D1 cells. J Auton Pharmacol. 1996 Dec; 16(6):311-3. PMID: 9131405.
      View in: PubMed
    68. Hecht JH, Weiner JA, Post SR, Chun J. Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex. J Cell Biol. 1996 Nov; 135(4):1071-83. PMID: 8922387.
      View in: PubMed
    69. Post SR, Jacobson JP, Insel PA. P2 purinergic receptor agonists enhance cAMP production in Madin-Darby canine kidney epithelial cells via an autocrine/paracrine mechanism. J Biol Chem. 1996 Jan 26; 271(4):2029-32. PMID: 8567655.
      View in: PubMed
    70. Post SR, Aguila-Buhain O, Insel PA. A key role for protein kinase A in homologous desensitization of the beta 2-adrenergic receptor pathway in S49 lymphoma cells. J Biol Chem. 1996 Jan 12; 271(2):895-900. PMID: 8557702.
      View in: PubMed
    71. Post SR, Hilal-Dandan R, Urasawa K, Brunton LL, Insel PA. Quantification of signalling components and amplification in the beta-adrenergic-receptor-adenylate cyclase pathway in isolated adult rat ventricular myocytes. Biochem J. 1995 Oct 01; 311 ( Pt 1):75-80. PMID: 7575483.
      View in: PubMed
    72. Jasper JR, Post SR, Desai KH, Insel PA, Bernstein D. Colchicine and cytochalasin B enhance cyclic AMP accumulation via postreceptor actions. J Pharmacol Exp Ther. 1995 Aug; 274(2):937-42. PMID: 7636757.
      View in: PubMed
    73. Post SR, Rubinstein PG, Tager HS. Mechanism of action of des-His1-[Glu9]glucagon amide, a peptide antagonist of the glucagon receptor system. Proc Natl Acad Sci U S A. 1993 Mar 01; 90(5):1662-6. PMID: 8383321.
      View in: PubMed
    74. Post SR, Miyazaki H, Tager HS. Identification of a Mg(2+)- and guanyl nucleotide-dependent glucagon receptor cycle by use of permeabilized canine hepatocytes. J Biol Chem. 1992 Dec 25; 267(36):25776-85. PMID: 1334486.
      View in: PubMed
    75. Yamada Y, Post SR, Wang K, Tager HS, Bell GI, Seino S. Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney. Proc Natl Acad Sci U S A. 1992 Jan 01; 89(1):251-5. PMID: 1346068.
      View in: PubMed
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