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Sue Griffin

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentGeriatrics, College of Medicine
DivisionGeriatrics Faculty
Address4104 Institute on Aging
629 Jack Stephens Drive
Mail Slot # 807
Little Rock AR 72205
Phone501-526-5801
ORCID ORCID Icon0000-0002-0405-7800 Additional info
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    Other Positions
    TitleProfessor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentNeurobiology & Developmental Science, College of Medicine

    TitleProfessor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentPediatrics, College of Medicine

    TitleProfessor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentPhysiology and Cell Biology, College of Medicine

    TitleProfessor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentPsychiatry, College of Medicine


    Collapse Research 
    Collapse research activities and funding
    1R01AG084472-01     (GRIFFIN, SUE T)May 1, 2023 - Jan 31, 2028
    NIH/Nat. Inst. on Aging
    Neuroinflammation, Protein Aggregates, ApoE4 Drug Targeting, and Autophagy Rescue
    Role: Principal Investigator
    1R01AG084472-02     (GRIFFIN, SUE T)May 1, 2023 - Jan 31, 2028
    NIH/Nat. Inst. on Aging
    Neuroinflammation, Protein Aggregates, ApoE4 Drug Targeting, and Autophagy Rescue
    Role: Principal Investigator
    R01AG084472     (GRIFFIN, SUE TILTON)May 1, 2023 - Jan 31, 2028
    NIH
    Neuroinflammation, Protein Aggregates, ApoE4 Drug Targeting, and Autophagy Rescue
    Role: Principal Investigator
    R01AG071782     (BARGER, STEVEN W)Apr 15, 2021 - Dec 31, 2025
    NIH
    Compromised function of a glial glucose transporter in aging and Alzheimer's disease
    Role: Co-Investigator
    R01AG034980     (CHEN, YUZHI)Apr 15, 2010 - Mar 31, 2016
    NIH/Nat. Inst. on Aging
    Amyloid Precursor Protein and Ubiquitination
    Role: Co-Investigator
    P20RR020146     (GARCIA-RILL, EDGAR E.)Sep 16, 2004 - Apr 30, 2014
    NIH
    Center for Translational Neuroscience
    Role: Co-Investigator
    R01HD037989     (GRIFFIN, SUE T)Jul 1, 2000 - Jun 30, 2007
    NIH
    CYTOKINES, NEURODEGENERATION AND DOWN'S SYNDROME
    Role: Principal Investigator
    P01AG012411     (GRIFFIN, SUE TILTON)Jun 1, 1995 - May 31, 2021
    NIH
    Early Events in Alzheimer Pathogenesis
    Role: Principal Investigator
    R01NS027414     (GRIFFIN, SUE T)Aug 1, 1990 - Jul 31, 1995
    NIH
    GENE EXPRESSION IN BRAIN CELLS IN AIDS
    Role: Principal Investigator
    R01AG005537     (GRIFFIN, SUE T)Feb 1, 1985 - Nov 30, 1988
    NIH
    ALTERED GENE EXPRESSION IN ALZHEIMER SENILE DEMENTIA
    Role: Principal Investigator
    R01AI014663     (GRIFFIN, SUE T)Apr 1, 1981 - Jan 31, 1989
    NIH
    BRAIN DEVELOPMENT AND GRAFT VERSUS HOST DISEASE
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Kakraba S, Ayyadevara S, Mainali N, Balasubramaniam M, Bowroju S, Penthala NR, Atluri R, Barger SW, Griffin ST, Crooks PA, Shmookler Reis RJ. Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan. Pharmaceuticals (Basel). 2023 Oct 20; 16(10). PMID: 37895969.
      View in: PubMed
    2. Balasubramaniam M, Ayyadevara S, Ganne A, Kakraba S, Penthala NR, Du X, Crooks PA, Griffin ST, Shmookler Reis RJ. Aggregate Interactome Based on Protein Cross-linking Interfaces Predicts Drug Targets to Limit Aggregation in Neurodegenerative Diseases. iScience. 2019 Oct 25; 20:248-264. PMID: 31593839.
      View in: PubMed
    3. Aboud O, Mrak RE, Boop FA, Griffin WS. Epilepsy: neuroinflammation, neurodegeneration, and APOE genotype. Acta Neuropathol Commun. 2013 Jul 29; 1:41. PMID: 24252240.
      View in: PubMed
    4. Aboud O, Mrak RE, Boop F, Griffin ST. Apolipoprotein epsilon 3 alleles are associated with indicators of neuronal resilience. BMC Med. 2012 Apr 13; 10:35. PMID: 22502727.
      View in: PubMed
    5. Griffin WS. Excess betaCTF, not Abeta: the culprit in Alzheimer-related endocytic dysfunction. Proc Natl Acad Sci U S A. 2010 Jan 26; 107(4):1263-4. PMID: 20133888.
      View in: PubMed
    6. Chopra MP, Landes RD, Jones RA, Feldman ZL, Beck C, Griffin ST. Does the apolipoprotein E epsilon 4 genotype influence the expression of depression with cognitive impairment? Int J Geriatr Psychiatry. 2009 Jun; 24(6):650-2. PMID: 19441046.
      View in: PubMed
    7. Thal DR, Griffin WS, Braak H. Parenchymal and vascular Abeta-deposition and its effects on the degeneration of neurons and cognition in Alzheimer's disease. J Cell Mol Med. 2008; Epub ahead of print.
    8. Thal DR, Griffin WS, De Vos RA, Ghebremedhin E. Cerebral amyloid angiopathy and its relationship to Alzheimer's disease. Acta Neuropathol. 2008; 115(6):599-609.
    9. Shaftel SS, Griffin WS, O'Banion MK. The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective. J Neuroinflammation. 2008; 5:7.
    10. Griffin WS. Perispinal etanercept: potential as an Alzheimer therapeutic. J Neuroinflammation. 2008 Jan 10; 5:3. PMID: 18186919.
      View in: PubMed
    11. E Nunez, C Benito, R.M. Tolon, C.J. Hillard, W.S.T. Griffin, J. Romero. Glilal Expression of Cannabinoid Cb2 Receptors and Fatty Acid Amide Hydrolase Are Beta Amyloid- Linked Events in Down's Syndorme. Neuroscience. 2008; 151:104-110.
    12. Barger SW, Dewall KM, Liu L, Mrak RE, Griffin WS. Relationships between expression of apolipoprotein E and B-amyloid precursor protein are altered in proximity to Alzheimer B-amyloid plaques; potential explanations from cell culture studies. J Neuropathol Exp Neurol. 2008; 67:773-783.
    13. Kolsch H, Larionov S, Dedeck O, Orantes M, Birkenmeier G, Griffin WS, Thal DR. Association of the glutathione S-transferase omega-1 Ala140Asp polymorphism with cerebrovascular artherosclerosis and plaque-associated interleukin-1 alpha expression. Stroke. 2007; 38(10):2847-50.
    14. Mrak RE, Griffin WS. Common inflammatory mechanisms in Lewy body disease and Alzheimer disease. J Neuropathol Exp Neurol. 2007; 66(8):683-6.
    15. Chen Y, Bodles AM, McPhie DL, Neve RL, Mrak RE, Griffin WS. APP-BP1 inhibits Abeta42 levels by interacting with Presenilin-1. Mol Neurodegener. 2007; 2:3.
    16. Mrak RE, Griffin WST. Dementiawith Lewy Bodies. Definition, Diagnosis, and pathogenic relationship to Alzheimer's disease. Neuropsychiatr Dis Treat. 2007; 3:619-625.
    17. Griffin WS, Liu L, Li Y, Mrak RE, Barger SW. Interleukin-1 mediates Alzheimer and Lewy body pathologies. J Neuroinflammation. 2006 Mar 16; 3:5. PMID: 16542445.
      View in: PubMed
    18. Griffin WS. Inflammation and neurodegenerative diseases. Am J Clin Nutr. 2006 Feb; 83(2):470S-474S. PMID: 16470015.
      View in: PubMed
    19. Griffin WS, Mrak RE. Interleukin-1 in the genesis and progression of and risk for development of neuronal degeneration in Alzheimer's disease. J Leukoc Biol. 2002 Aug; 72(2):233-8. PMID: 12149413.
      View in: PubMed
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