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Last Name
Institution

Maxim Dobretsov

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentAnesthesiology, College of Medicine
Address258 Biomedical Research I
325 S. Elm St.
Mail Slot # 515
Little Rock AR 72205
Phone501-526-7150
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    Other Positions
    TitleAssociate Professor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentNeurobiology & Developmental Science, College of Medicine

    TitleAssociate Professor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentPhysiology and Biophysics, College of Medicine


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Yadlapalli JSK, Dogra N, Walbaum AW, Wessinger WD, Prather PL, Crooks PA, Dobretsov M. Evaluation of Analgesia, Tolerance, and the Mechanism of Action of Morphine-6-O-Sulfate Across Multiple Pain Modalities in Sprague-Dawley Rats. Anesth Analg. 2017 May 04. PMID: 28489639.
      View in: PubMed
    2. Yadlapalli JS, Ford BM, Ketkar A, Wan A, Penthala NR, Eoff RL, Prather PL, Dobretsov M, Crooks PA. Antinociceptive effects of the 6-O-sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors. Pharmacol Res. 2016 Nov; 113(Pt A):335-347. PMID: 27637375.
      View in: PubMed
    3. Chowdhury P, Akel N, Jamshidi-Parsian A, Gaddy D, Griffin RJ, Yadlapalli JS, Dobretsov M. Degenerative Tissue Responses to Space-like Radiation Doses in a Rodent Model of Simulated Microgravity. Ann Clin Lab Sci. 2016; 46(2):190-7. PMID: 27098627.
      View in: PubMed
    4. Climer LK, Dobretsov M, Lupashin V. Defects in the COG complex and COG-related trafficking regulators affect neuronal Golgi function. Front Neurosci. 2015; 9:405. PMID: 26578865; PMCID: PMC4621299.
      View in: PubMed, PubMed Central
    5. Chowdhury P, Long A, Harris G, Soulsby ME, Dobretsov M. Animal model of simulated microgravity: a comparative study of hindlimb unloading via tail versus pelvic suspension. Physiol Rep. 2013 Jun; 1(1):e00012. PMID: 24303103; PMCID: PMC3831940.
      View in: PubMed, PubMed Central
    6. Chowdhury, P, Long, A, Harris, G, Soulsby, M.E, Dobretsov, M. Animal Model of Simulated Microgravity: A comparative study of hindlimb unloading via tail vs. pelvic suspension. Physiol Rep. 2013; 1:1-15.
    7. Kubasov IV, Dobretsov M. Two types of extracellular action potentials recorded with narrow-tipped pipettes in skeletal muscle of frog, Rana temporaria. J Physiol. 2012 Jun 15; 590(12):2937-44. PMID: 22526885; PMCID: PMC3448157.
      View in: PubMed, PubMed Central
    8. Chowdhury P, Soulsby ME, Jayroe J, Akel NS, Gaddy D, Dobretsov M. Pressure hyperalgesia in hind limb suspended rats. Aviat Space Environ Med. 2011 Oct; 82(10):988-91. PMID: 21961404.
      View in: PubMed
    9. Kubasov, I.V, Dobretsov M. Characteristics of spreading action potentials recorded in various areas of skeletal muscle fibers of the frog Rana temporaria. J Evolut Biochem Physiol. 2011; 47:486-489.
    10. Khaidakov M, Szwedo J, Mitra S, Ayyadevara S, Dobretsov M, Lu J, Mehta JL. Antiangiogenic and antimitotic effects of aspirin in hypoxia–reoxygenation modulation of the LOX-1-NADPH oxidase axis as a potential mechanism. J Cardiovasc Pharmacol. 2010 Dec; 56(6):635-41. PMID: 20881612.
      View in: PubMed
    11. Dobretsov M, Stimers JR. Muscle spindle afferents and the mystery of the a3 isoform of Na+,K+-ATPase. J Physiol. 2010 Nov 01; 588(Pt 21):4061. PMID: 21037311; PMCID: PMC3002435.
      View in: PubMed, PubMed Central
    12. Romanovsky D, Dobretsov M. Pressure-induced pain: early sign of diabetes-associated impairment of insulin production in rats. Neurosci Lett. 2010 Oct 11; 483(2):110-3. PMID: 20678544; PMCID: PMC2933320.
      View in: PubMed, PubMed Central
    13. Khaidakov, M, Szwedo, J, Mitra, S, Ayyadevara, S, Dobretsov M, Lu, J, Mehta, J.L. Anti-angiogenic and anti-mitotic effects of aspirin in hypoxia-reoxygination modulation of LOX-1-NADPH oxidase axis as potential mechanism. J. Cardiovasc. Pharmacol. 2010; 56:635-641.
    14. Dobretsov M, Backonja M, Romanovsky D, Stimers J.R. Animal Models of Pain. Animal Models of Diabetic Neuropathic Pain. 2010; 9.
    15. LaCroix-Fralish ML, Mo G, Smith SB, Sotocinal SG, Ritchie J, Austin JS, Melmed K, Schorscher-Petcu A, Laferriere AC, Lee TH, Romanovsky D, Liao G, Behlke MA, Clark DJ, Peltz G, Séguéla P, Dobretsov M, Mogil JS. The beta3 subunit of the Na+,K+-ATPase mediates variable nociceptive sensitivity in the formalin test. Pain. 2009 Aug; 144(3):294-302. PMID: 19464798; PMCID: PMC2744953.
      View in: PubMed, PubMed Central
    16. LaCroix-Fralish, M.L, Mo, G, Smith, S.B, Sotocinal, S.G, Ritchie, J, Austin, J.-S, Melmed, K, Schorsher-Petcu, A, Laferriere, A.C, Lee, T.H, Romanovsky, D, Liao, G, Behlke, M.A, Clark, D.J, Peltz, G, Seguela, P, Dobretsov, M, Mogil, J.S. The ß3 subunit of the Na+,K+-ATPase mediate variable nociceptive sensitivity in the formalin test. Pain. 2009; 144:294-302.
    17. Dobretsov M, Romanovsky D, Smith AG, Stimers JR. Mechanisms of Pain in Peripheral Neuropathy. Diabetic neuropathy and pain. 2009; 11.
    18. Chowdhury P, Dobretsov M. A report of the Sixth Annual Meeting of the International Society for the Prevention of Tobacco Induced Diseases (ISPTID). Tob Induc Dis. 2008 Dec 17; 4:11. PMID: 19091067; PMCID: PMC2614959.
      View in: PubMed, PubMed Central
    19. Romanovsky D, Walker JC, Dobretsov M. Pressure pain precedes development of type 2 disease in Zucker rat model of diabetes. Neurosci Lett. 2008 Nov 21; 445(3):220-3. PMID: 18790004; PMCID: PMC2585493.
      View in: PubMed, PubMed Central
    20. Liu BG, Dobretsov M, Stimers JR, Zhang JM. Tumor necrosis factor-a suppresses sustained potassium currents in rat small diameter sensory neurons. The Open Pain Journal. 2008; 1:01-07.
    21. Liu BG, Dobretsov M, Stimers JR, Zhang JM. Tumor Necrosis Factor-alpha Suppresses Activation of Sustained Potassium Currents in Rat Small Diameter Sensory Neurons. Open Pain J. 2008; 1:1 - .
    22. Liu BG, Dobretsov M, Stimers JR, Zhang JM. Tumor Necrosis Factor-a Suppresses Activation of Sustained Potassium Currents in Rat Small Diameter Sensory Neurons. Open Pain J. 2008 Jan 01; 1:1. PMID: 20165558.
      View in: PubMed
    23. Romanovsky D, Moseley AE, Mrak RE, Taylor MD, Dobretsov M. Phylogenetic preservation of alpha3 Na+,K+-ATPase distribution in vertebrate peripheral nervous systems. J Comp Neurol. 2007 Feb 20; 500(6):1106-16. PMID: 17183534.
      View in: PubMed
    24. Dobretsov M, Romanovsky D, Stimers JR. Early diabetic neuropathy: triggers and mechanisms. World J Gastroenterol. 2007 Jan 14; 13(2):175-91. PMID: 17226897; PMCID: PMC1829411.
      View in: PubMed, PubMed Central
    25. Kim JH, Sizov I, Dobretsov M, von Gersdorff H. Presynaptic Ca2+ buffers control the strength of a fast post-tetanic hyperpolarization mediated by the alpha3 Na(+)/K(+)-ATPase. Nat Neurosci. 2007 Feb; 10(2):196-205. PMID: 17220883.
      View in: PubMed
    26. Dobretsov M, Ghaleb AH, Romanovsky D, Pablo CS, Stimers JR. Impaired insulin signaling as a potential trigger of pain in diabetes and prediabetes. Int Anesthesiol Clin. 2007; 45(2):95-105. PMID: 17426511.
      View in: PubMed
    27. Kim JH, Sizov I, Dobretsov M, Von Gersdorff H. Presynaptic Ca2+ buffers control the strength of a fast post-tetanic hyperpolization mediated by the a3 Na+/K+ -ATPase. Nature Neuroscience. 2007; 10:196-205.
    28. Romanovsky D, Cruz NF, Dienel GA, Dobretsov M. Mechanical hyperalgesia correlates with insulin deficiency in normoglycemic streptozotocin-treated rats. Neurobiol Dis. 2006 Nov; 24(2):384-94. PMID: 16935517.
      View in: PubMed
    29. Dobretsov M, Romanovsky D. "Clock-scan" protocol for image analysis. Am J Physiol Cell Physiol. 2006 Nov; 291(5):C869-79. PMID: 16738004.
      View in: PubMed
    30. Dobretsov M, Stimers JR. Neuronal function and alpha3 isoform of the Na/K-ATPase. Front Biosci. 2005 Sep 01; 10:2373-96. PMID: 15970502.
      View in: PubMed
    31. Romanovsky D, Light KE, Walker J, Dobretsov M. Target-determined expression of alpha3 isoform of the Na+,K+-ATPase in the somatic nervous system of rat. J Comp Neurol. 2005 Feb 28; 483(1):114-23. PMID: 15672395.
      View in: PubMed
    32. Romanovsky D, Hastings SL, Stimers JR, Dobretsov M. Relevance of hyperglycemia to early mechanical hyperalgesia in streptozotocin-induced diabetes. J Peripher Nerv Syst. 2004 Jun; 9(2):62-9. PMID: 15104693.
      View in: PubMed
    33. Krivoi I, Vasiliev A, Kravtsova V, Dobretsov M, Mandel F. Porcine kidney extract contains factor(s) that inhibit the ouabain-sensitive isoform of Na,K-ATPase (alpha2) in rat skeletal muscle: a convenient electrophysiological assay. Ann N Y Acad Sci. 2003; 986:639 - 641.
    34. Dobretsov M, Hastings SL, Romanovsky D, Stimers JR, Zhang JM. Mechanical hyperalgesia in rat models of systemic and local hyperglycemia. Brain Res. 2003 Jan 17; 960(1-2):174-83. PMID: 12505670.
      View in: PubMed
    35. Dobretsov M, Hastings SL, Sims TJ, Stimers JR, Romanovsky D. Stretch receptor-associated expression of alpha 3 isoform of the Na+, K+-ATPase in rat peripheral nervous system. Neuroscience. 2003; 116(4):1069-80. PMID: 12617948.
      View in: PubMed
    36. Ha J, Dobretsov M, Kurten RC, Grant DF, Stimers JR. Effect of linoleic acid metabolites on Na(+)/K(+) pump current in N20.1 oligodendrocytes: role of membrane fluidity. Toxicol Appl Pharmacol. 2002 Jul 01; 182(1):76-83. PMID: 12127265.
      View in: PubMed
    37. Li H, Liu BG, Dobretsov M, Brull SJ, Zhang JM. Thermosensitivity of large primary sensory neurons. Brain Res. 2002 Feb 01; 926(1-2):18-26. PMID: 11814402.
      View in: PubMed
    38. Dobretsov M, Hastings SL, Stimers JR, Zhang JM. Mechanical hyperalgesia in rats with chronic perfusion of lumbar dorsal root ganglion with hyperglycemic solution. J Neurosci Methods. 2001 Sep 30; 110(1-2):9-15. PMID: 11564519.
      View in: PubMed
    39. Dobretsov M, Dobretsov A, Kuffler DP. Influence of factors released from sciatic nerve on adult dorsal root ganglion neurons. J Neurobiol. 1994; 25(10):1249 - 1266.
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