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Clint Kilts

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPsychiatry, College of Medicine
DivisionPSY Brain Imaging Research Center
Address Campus General
4224 Shuffield Dr.
Mail Slot # 554
Little Rock AR 72205
Phone501-526-8163
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    Collapse Overview 
    Collapse overview
    Dr. Kilts received his postgraduate training in psychopharmacology and neurochemistry in the Department of Pharmacology and Toxicology at Michigan State University. He continued his training in neuropharmacology, analytical neurochemistry, and human psychopharmacology in the Biological Sciences Research Center at the University of North Carolina. He subsequently joined the faculties of the Departments of Psychiatry and Pharmacology at Duke University where he served as Director of the Clinical Psychopharmacology Laboratory. In 1992, Dr. Kilts joined the faculty of the Department of Psychiatry and Behavioral Sciences in the Emory University School of Medicine. At Emory, he served as the Interim Director of the Center for Positron Emission Tomography (PET) and, in 2000, became the first Vice Chair for Research for the Department of Psychiatry and Behavioral Sciences. In 2009, he joined the faculty of the Department of Psychiatry and Behavioral Sciences in the College of Medicine at the University of Arkansas for Medical Sciences (UAMS). He is the founding Director of the Brain Imaging Research Center (BIRC) in the UAMS Psychiatric Research Institute (PRI) and an Associate Director of the PRI. He has a long record of NIH-funded research, most recently in the use of in vivo brain functional, molecular and connectivity imaging to explore the neural network processing basis of human behavior. With a focus on drug abuse and addiction, he has a clinical research focus on the use of neuroimaging technology to define the brain basis of psychiatric disorders and their treatment. Additional academic accomplishments relate to organizational research planning, organization, and mentoring. His current goals as Director of the BIRC are to extend magnetic resonance imaging (MRI)-based technology and human neuroscience to areas of clinical problem solving in psychiatry and related disciplines within the PRI and at UAMS.


    Collapse Research Funds 
    Collapse research activities
    27312     (ESCALONA-VARGAS, DIANA)Jan 15, 2019 - Jan 14, 2021
    Brain & Behavior Research Foundation
    Studying the effect of Buprenorphine on Fetal Brain Development Using Magnetoencephalography
    Role: Co-Investigator

    R01DA044608     (KILTS, CLINT)Jul 1, 2018 - Apr 30, 2023
    NIH/Nat. Inst. on Drug Abuse
    The sex-specific roles and neural processing correlates of future outcome estimation in the drug addiction process
    Role: Principal Investigator

    BI Trial No. 1289-0032     (KILTS, CLINT)Jun 25, 2018
    Boehringer Ingleheim Pharmaceuticals, Inc.
    A phase II randomised, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of orally administered BI 409306 during a 52-week treatment period as an early intervention in patients with attenuated psychosis syndrome.
    Role: Principal Investigator

    F30DA043928     (MARTINS, BRADFORD)Mar 30, 2018 - Mar 29, 2021
    NIH/Nat. Inst. on Drug Abuse
    Multi-Level Modeling of Addiction Comorbidity
    Role: Co-Investigator

    1735820     (BUSH, KEITH)Sep 1, 2017 - Feb 28, 2021
    National Science Foundation
    Cognitive Control Theoretic Mechanisms of Real-time fMRI-Guided Neuromodulation
    Role: Co-Investigator

    R21DA042396     (JAMES, GEORGE ANDREW)Sep 1, 2017 - Aug 31, 2019
    NIH/NIDA
    Modeling sex-differences in trauma-related neural organization conferring resilience against addiction
    Role: Co-Investigator

    R21MH108753     (JAMES, GEORGE)Mar 7, 2017 - Dec 31, 2018
    NIH/Nat. Inst. of Mental Health - Pass Through: University of Wisconsin-Madison
    Dopamine Enhancement of Fear Extinction Learning in PTSD
    Role: Co-Investigator

    R21MH106860     (CISLER, JOSHUA)Apr 15, 2015 - Jan 31, 2017
    NIH/Nat. Inst. of Mental Health
    A critical test of neural models of risk among adolescent assault victims
    Role: Co-Investigator

    R01DA036360     (KILTS, CLINT)May 15, 2014 - Mar 31, 2020
    NIH/Nat. Inst. on Drug Abuse
    A risk factor analysis of human brain states related to development of addiction
    Role: Principal Investigator

    R21MH097784     (CISLER, JOSHUA)Jun 15, 2012 - May 31, 2015
    NIH/Nat. Inst. of Mental Health
    Neural Network Predictors of Treatment Outcome Among Adolescent Assault Victims
    Role: Co-Investigator

    R21DA029442     (KILTS, CLINT)Apr 1, 2012 - Mar 31, 2014
    NIH/Nat. Inst. on Drug Abuse - Pass Through: Dartmouth College
    The Neuroeconomics of Behavioral Therapies for Adolescent Substance Abuse - Imaging
    Role: Principal Investigator

    U19MH069056     (KILTS, CLINT)Aug 1, 2009 - Jul 31, 2014
    NIH/Nat. Inst. of Mental Health - Pass Through: Emory University
    Emory-MSSM_GSK-NIMH collaborative Mood and Anxiety Disorders Initiative
    Role: Principal Investigator

    R21DA025243     (KILTS, CLINT)Jun 15, 2008 - May 31, 2011
    NIH/Nat. Inst. on Drug Abuse
    The Clinical and Neural Response of Cocaine Addicts to Combination Treatment with
    Role: Principal Investigator

    R01DA019999     (KILTS, CLINT)May 1, 2007 - Feb 28, 2012
    NIH/Nat. Inst. on Drug Abuse
    AN FMRI STUDY OF THE IMPACT OF STRESS ON DRUG ADDICTION
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Cisler JM, Privratsky AA, Sartin-Tarm A, Sellnow K, Ross M, Weaver S, Hahn E, Herringa RJ, James GA, Kilts CD. L-DOPA and consolidation of fear extinction learning among women with posttraumatic stress disorder. Transl Psychiatry. 2020 08 15; 10(1):287. PMID: 32801342.
      View in: PubMed
    2. Stehouwer JS, Birnbaum MS, Voll RJ, Owens MJ, Plott SJ, Bourke CH, Wassef MA, Kilts CD, Goodman MM. Erratum to "Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor" [Bioorg. Med. Chem. 23 (2015) 4286-4302]. Bioorg Med Chem. 2020 Oct 01; 28(19):115660. PMID: 32747078.
      View in: PubMed
    3. Wilson KA, James GA, Kilts CD, Bush KA. Combining Physiological and Neuroimaging Measures to Predict Affect Processing Induced by Affectively Valent Image Stimuli. Sci Rep. 2020 Jun 09; 10(1):9298. PMID: 32518277.
      View in: PubMed
    4. Elton A, Stanger C, James GA, Ryan-Pettes S, Budney A, Kilts CD. Intertemporal decision-making-related brain states predict adolescent drug abuse intervention responses. Neuroimage Clin. 2019; 24:101968. PMID: 31404876.
      View in: PubMed
    5. Cáceda R, James GA, Stowe ZN, Delgado PL, Kordsmeier N, Kilts CD. The neural correlates of low social integration as a risk factor for suicide. Eur Arch Psychiatry Clin Neurosci. 2020 Aug; 270(5):619-631. PMID: 30903270.
      View in: PubMed
    6. Chung MH, Martins B, Privratsky A, James GA, Kilts CD, Bush KA. Individual differences in rate of acquiring stable neural representations of tasks in fMRI. PLoS One. 2018; 13(11):e0207352. PMID: 30475812.
      View in: PubMed
    7. Bush KA, Privratsky A, Gardner J, Zielinski MJ, Kilts CD. Common Functional Brain States Encode both Perceived Emotion and the Psychophysiological Response to Affective Stimuli. Sci Rep. 2018 10 18; 8(1):15444. PMID: 30337576.
      View in: PubMed
    8. Martins BS, Cáceda R, Cisler JM, Kilts CD, James GA. The neural representation of the association between comorbid drug use disorders and childhood maltreatment. Drug Alcohol Depend. 2018 11 01; 192:215-222. PMID: 30268937.
      View in: PubMed
    9. Cisler JM, Esbensen K, Sellnow K, Ross M, Weaver S, Sartin-Tarm A, Herringa RJ, Kilts CD. Differential Roles of the Salience Network During Prediction Error Encoding and Facial Emotion Processing Among Female Adolescent Assault Victims. Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 04; 4(4):371-380. PMID: 30343131.
      View in: PubMed
    10. Zielinski MJ, Privratsky AA, Smitherman S, Kilts CD, Herringa RJ, Cisler JM. Does development moderate the effect of early life assaultive violence on resting-state networks? An exploratory study. Psychiatry Res Neuroimaging. 2018 11 30; 281:69-77. PMID: 30266022.
      View in: PubMed
    11. Cáceda R, Bush K, James GA, Stowe ZN, Kilts CD. Modes of Resting Functional Brain Organization Differentiate Suicidal Thoughts and Actions: A Preliminary Study. J Clin Psychiatry. 2018 07 10; 79(4). PMID: 29995357.
      View in: PubMed
    12. Brents LK, James GA, Cisler JM, Kilts CD. Personality variables modify the relationship between childhood maltreatment history and poor functional outcomes. Psychiatry Res. 2018 10; 268:229-237. PMID: 30064070.
      View in: PubMed
    13. Bush KA, Gardner J, Privratsky A, Chung MH, James GA, Kilts CD. Brain States That Encode Perceived Emotion Are Reproducible but Their Classification Accuracy Is Stimulus-Dependent. Front Hum Neurosci. 2018; 12:262. PMID: 30013469.
      View in: PubMed
    14. Ross MC, Lenow JK, Kilts CD, Cisler JM. Altered neural encoding of prediction errors in assault-related posttraumatic stress disorder. J Psychiatr Res. 2018 08; 103:83-90. PMID: 29783079.
      View in: PubMed
    15. Steele JS, Bush K, Stowe ZN, James GA, Smitherman S, Kilts CD, Cisler J. Implicit emotion regulation in adolescent girls: An exploratory investigation of Hidden Markov Modeling and its neural correlates. PLoS One. 2018; 13(2):e0192318. PMID: 29489856.
      View in: PubMed
    16. Cisler JM, Privratsky A, Smitherman S, Herringa RJ, Kilts CD. Large-scale brain organization during facial emotion processing as a function of early life trauma among adolescent girls. Neuroimage Clin. 2018; 17:778-785. PMID: 29527485.
      View in: PubMed
    17. Bush KA, Inman CS, Hamann S, Kilts CD, James GA. Distributed Neural Processing Predictors of Multi-dimensional Properties of Affect. Front Hum Neurosci. 2017; 11:459. PMID: 28959198.
      View in: PubMed
    18. Cáceda R, Prendes-Alvarez S, Hsu JJ, Tripathi SP, Kilts CD, James GA. The neural correlates of reciprocity are sensitive to prior experience of reciprocity. Behav Brain Res. 2017 08 14; 332:136-144. PMID: 28551067.
      View in: PubMed
    19. Cisler JM, Sigel BA, Kramer TL, Smitherman S, Vanderzee K, Pemberton J, Kilts CD. Modes of Large-Scale Brain Network Organization during Threat Processing and Posttraumatic Stress Disorder Symptom Reduction during TF-CBT among Adolescent Girls. PLoS One. 2016; 11(8):e0159620. PMID: 27505076.
      View in: PubMed
    20. James GA, Kearney-Ramos TE, Young JA, Kilts CD, Gess JL, Fausett JS. Functional independence in resting-state connectivity facilitates higher-order cognition. Brain Cogn. 2016 06; 105:78-87. PMID: 27105037.
      View in: PubMed
    21. Stehouwer JS, Bourke CH, Owens MJ, Voll RJ, Kilts CD, Goodman MM. Synthesis, binding affinity, radiolabeling, and microPET evaluation of 4-(2-substituted-4-substituted)-8-(dialkylamino)-6-methyl-1-substituted-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-ones as ligands for brain corticotropin-releasing factor type-1 (CRF1) receptors. Bioorg Med Chem Lett. 2015 Nov 15; 25(22):5111-4. PMID: 26456805.
      View in: PubMed
    22. Cisler JM, Sigel BA, Kramer TL, Smitherman S, Vanderzee K, Pemberton J, Kilts CD. Amygdala response predicts trajectory of symptom reduction during Trauma-Focused Cognitive-Behavioral Therapy among adolescent girls with PTSD. J Psychiatr Res. 2015 Dec; 71:33-40. PMID: 26522869.
      View in: PubMed
    23. Bush K, Zhou S, Cisler J, Bian J, Hazaroglu O, Gillispie K, Yoshigoe K, Kilts C. A deconvolution-based approach to identifying large-scale effective connectivity. Magn Reson Imaging. 2015 Dec; 33(10):1290-1298. PMID: 26248273.
      View in: PubMed
    24. Cisler JM, Bush K, James GA, Smitherman S, Kilts CD. Decoding the Traumatic Memory among Women with PTSD: Implications for Neurocircuitry Models of PTSD and Real-Time fMRI Neurofeedback. PLoS One. 2015; 10(8):e0134717. PMID: 26241958.
      View in: PubMed
    25. Bush K, Cisler J, Bian J, Hazaroglu G, Hazaroglu O, Kilts C. Improving the precision of fMRI BOLD signal deconvolution with implications for connectivity analysis. Magn Reson Imaging. 2015 Dec; 33(10):1314-1323. PMID: 26226647.
      View in: PubMed
    26. Cáceda R, James GA, Gutman DA, Kilts CD. Organization of intrinsic functional brain connectivity predicts decisions to reciprocate social behavior. Behav Brain Res. 2015 Oct 01; 292:478-83. PMID: 26166191.
      View in: PubMed
    27. Stehouwer JS, Birnbaum MS, Voll RJ, Owens MJ, Plott SJ, Bourke CH, Wassef MA, Kilts CD, Goodman MM. Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor. Bioorg Med Chem. 2015 Aug 01; 23(15):4286-4302. PMID: 26145817.
      View in: PubMed
    28. Brents LK, Tripathi SP, Young J, James GA, Kilts CD. The role of childhood maltreatment in the altered trait and global expression of personality in cocaine addiction. J Psychiatr Res. 2015 May; 64:23-31. PMID: 25805246.
      View in: PubMed
    29. Cisler JM, Bush K, Scott Steele J, Lenow JK, Smitherman S, Kilts CD. Brain and behavioral evidence for altered social learning mechanisms among women with assault-related posttraumatic stress disorder. J Psychiatr Res. 2015 Apr; 63:75-83. PMID: 25769397.
      View in: PubMed
    30. Elton A, Smitherman S, Young J, Kilts CD. Effects of childhood maltreatment on the neural correlates of stress- and drug cue-induced cocaine craving. Addict Biol. 2015 Jul; 20(4):820-31. PMID: 25214317.
      View in: PubMed
    31. Gess JL, Fausett JS, Kearney-Ramos TE, Kilts CD, James GA. Task-dependent recruitment of intrinsic brain networks reflects normative variance in cognition. Brain Behav. 2014 Sep; 4(5):650-64. PMID: 25328842.
      View in: PubMed
    32. Kearney-Ramos TE, Fausett JS, Gess JL, Reno A, Peraza J, Kilts CD, James GA. Merging clinical neuropsychology and functional neuroimaging to evaluate the construct validity and neural network engagement of the n-back task. J Int Neuropsychol Soc. 2014 Aug; 20(7):736-50. PMID: 24963641.
      View in: PubMed
    33. Dunlop BW, Rothbaum BO, Binder EB, Duncan E, Harvey PD, Jovanovic T, Kelley ME, Kinkead B, Kutner M, Iosifescu DV, Mathew SJ, Neylan TC, Kilts CD, Nemeroff CB, Mayberg HS. Evaluation of a corticotropin releasing hormone type 1 receptor antagonist in women with posttraumatic stress disorder: study protocol for a randomized controlled trial. Trials. 2014 Jun 21; 15:240. PMID: 24950747.
      View in: PubMed
    34. Lenow JK, Scott Steele J, Smitherman S, Kilts CD, Cisler JM. Attenuated behavioral and brain responses to trust violations among assaulted adolescent girls. Psychiatry Res. 2014 Jul 30; 223(1):1-8. PMID: 24811608.
      View in: PubMed
    35. Kennedy AP, Gross RE, Ely T, Drexler KP, Kilts CD. Clinical correlates of attentional bias to drug cues associated with cocaine dependence. Am J Addict. 2014 Sep-Oct; 23(5):478-84. PMID: 24629029.
      View in: PubMed
    36. James GA, Tripathi SP, Kilts CD. Estimating brain network activity through back-projection of ICA components to GLM maps. Neurosci Lett. 2014 Apr 03; 564:21-6. PMID: 24513233.
      View in: PubMed
    37. Kilts CD, Kennedy A, Elton AL, Tripathi SP, Young J, Cisler JM, James GA. Individual differences in attentional bias associated with cocaine dependence are related to varying engagement of neural processing networks. Neuropsychopharmacology. 2014 Apr; 39(5):1135-47. PMID: 24196947.
      View in: PubMed
    38. Cisler JM, Steele JS, Lenow JK, Smitherman S, Everett B, Messias E, Kilts CD. Functional reorganization of neural networks during repeated exposure to the traumatic memory in posttraumatic stress disorder: an exploratory fMRI study. J Psychiatr Res. 2014 Jan; 48(1):47-55. PMID: 24139810.
      View in: PubMed
    39. Cisler JM, Scott Steele J, Smitherman S, Lenow JK, Kilts CD. Neural processing correlates of assaultive violence exposure and PTSD symptoms during implicit threat processing: a network-level analysis among adolescent girls. Psychiatry Res. 2013 Dec 30; 214(3):238-46. PMID: 23969000.
      View in: PubMed
    40. Stanger C, Elton A, Ryan SR, James GA, Budney AJ, Kilts CD. Neuroeconomics and adolescent substance abuse: individual differences in neural networks and delay discounting. J Am Acad Child Adolesc Psychiatry. 2013 Jul; 52(7):747-755.e6. PMID: 23800488.
      View in: PubMed
    41. Cisler JM, Elton A, Kennedy AP, Young J, Smitherman S, Andrew James G, Kilts CD. Altered functional connectivity of the insular cortex across prefrontal networks in cocaine addiction. Psychiatry Res. 2013 Jul 30; 213(1):39-46. PMID: 23684980.
      View in: PubMed
    42. Elton A, Tripathi SP, Mletzko T, Young J, Cisler JM, James GA, Kilts CD. Childhood maltreatment is associated with a sex-dependent functional reorganization of a brain inhibitory control network. Hum Brain Mapp. 2014 Apr; 35(4):1654-67. PMID: 23616424.
      View in: PubMed
    43. Nye JA, Purselle D, Plisson C, Voll RJ, Stehouwer JS, Votaw JR, Kilts CD, Goodman MM, Nemeroff CB. Decreased brainstem and putamen SERT binding potential in depressed suicide attempters using [11C]-zient PET imaging. Depress Anxiety. 2013 Oct; 30(10):902-7. PMID: 23526784.
      View in: PubMed
    44. Nye JA, Purselle D, Plisson C, Voll RJ, Stehouwer JS, Votaw JR, Kilts CD, Goodman MM, Nemeroff CB. DECREASED BRAINSTEM AND PUTAMEN SERT BINDING POTENTIAL IN DEPRESSED SUICIDE ATTEMPTERS USING [ C]-ZIENT PET IMAGING. Depress Anxiety. 2013.
    45. Elton A, Young J, Smitherman S, Gross RE, Mletzko T, Kilts CD. Neural network activation during a stop-signal task discriminates cocaine-dependent from non-drug-abusing men. Addict Biol. 2014 May; 19(3):427-38. PMID: 23231419.
      View in: PubMed
    46. Kennedy AP, Binder EB, Bowman D, Harenski K, Ely T, Cisler JM, Tripathi SP, VanNess S, Kilts CD. A common TPH2 haplotype regulates the neural processing of a cognitive control demand. . 2012 Oct; 159B(7):829-40. PMID: 22915309.
      View in: PubMed
    47. Kennedy AP, Gross RE, Whitfield N, Drexler KP, Kilts CD. A controlled trial of the adjunct use of D-cycloserine to facilitate cognitive behavioral therapy outcomes in a cocaine-dependent population. Addict Behav. 2012 Aug; 37(8):900-7. PMID: 22578380.
      View in: PubMed
    48. Kilts C, Ely TD. Human functional neuroimaging. Handb Clin Neurol. 2012; 106:97-105. PMID: 22608618.
      View in: PubMed
    49. Cisler JM, James GA, Tripathi S, Mletzko T, Heim C, Mayberg HS, Nemeroff CB, Kilts CD. ifferential functional connectivity within an emotion regulation network among individuals resilient and susceptible to the depressogenic effects of early life stress. Psychol Med. 2012; 43(3):507-518.
    50. Gilkey R, Caceda R, Bate A,, Robertson D, Kilts CD. Using the whole brain to improve strategic reasoning. NeuroLeadership Journal. 2012; (4):6-69.
    51. Cáceda R, James GA, Ely TD, Snarey J, Kilts CD. Mode of effective connectivity within a putative neural network differentiates moral cognitions related to care and justice ethics. PLoS One. 2011 Feb 25; 6(2):e14730. PMID: 21364916.
      View in: PubMed
    52. Derado G, Bowman FD, Kilts CD. Modeling the spatial and temporal dependence in FMRI data. Biometrics. 2010 Sep; 66(3):949-57. PMID: 19912175.
      View in: PubMed
    53. Gilkey R, Caceda R, Kilts C. When emotional reasoning trumps IQ. Harv Bus Rev. 2010 Sep; 88(9):27. PMID: 20821966.
      View in: PubMed
    54. Derado G, Bowman FD, Ely TD, Kilts CD. Evaluating Functional Autocorrelation within Spatially Distributed Neural Processing Networks. Stat Interface. 2010; 3(1):45-58. PMID: 21643436.
      View in: PubMed
    55. Kilts CD, Wade AG, Andersen HF, Schlaepfer TE. Baseline severity of depression predicts antidepressant drug response relative to escitalopram. Expert Opin Pharmacother. 2009 Apr; 10(6):927-36. PMID: 19317630.
      View in: PubMed
    56. Zeng F, Mun J, Jarkas N, Stehouwer JS, Voll RJ, Tamagnan GD, Howell L, Votaw JR, Kilts CD, Nemeroff CB, Goodman MM. Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 labeled reboxetine analogues: potential positron emission tomography radioligands for in vivo imaging of the norepinephrine transporter. J Med Chem. 2009 Jan 08; 52(1):62-73. PMID: 19067522.
      View in: PubMed
    57. Nye JA, Votaw JR, Jarkas N, Purselle D, Camp V, Bremner JD, Kilts CD, Nemeroff CB, Goodman MM. Compartmental modeling of 11C-HOMADAM binding to the serotonin transporter in the healthy human brain. J Nucl Med. 2008 Dec; 49(12):2018-25. PMID: 19038997.
      View in: PubMed
    58. Guo Y, DuBois Bowman F, Kilts C. Predicting the brain response to treatment using a Bayesian hierarchical model with application to a study of schizophrenia. Hum Brain Mapp. 2008 Sep; 29(9):1092-109. PMID: 17924543.
      View in: PubMed
    59. Nye JA, Votaw JR, Jarkas N, Camp V, Bremner JD, Kilts CD, Nemeroff CB, Goodman MM. Compartmental modeling of C-HOMADAM binding to the serotonin transporter in the healthy human brain. J Nuc Med. 2008; 49:2018-2025.
    60. Gilkey R, Kilts C. Cognitive fitness. Harv Bus Rev. 2007 Nov; 85(11):53-4, 56, 58 passim. PMID: 18159786.
      View in: PubMed
    61. Zeng F, Jarkas N, Stehouwer JS, Voll RJ, Owens MJ, Kilts CD, Nemeroff CB, Goodman MM. Synthesis, in vitro characterization, and radiolabeling of reboxetine analogs as potential PET radioligands for imaging the norepinephrine transporter. Bioorg Med Chem. 2008 Jan 15; 16(2):783-93. PMID: 17983754.
      View in: PubMed
    62. DuBois Bowman F, Caffo B, Bassett SS, Kilts C. A Bayesian hierarchical framework for spatial modeling of fMRI data. Neuroimage. 2008 Jan 01; 39(1):146-56. PMID: 17936016.
      View in: PubMed
    63. Duncan E, Boshoven W, Harenski K, Fiallos A, Tracy H, Jovanovic T, Hu X, Drexler K, Kilts C. An fMRI study of the interaction of stress and cocaine cues on cocaine craving in cocaine-dependent men. Am J Addict. 2007 May-Jun; 16(3):174-82. PMID: 17612820.
      View in: PubMed
    64. Zeng F, Stehouwer JS, Jarkas N, Voll RJ, Williams L, Camp VM, Votaw JR, Owens MJ, Kilts CD, Nemeroff CB, Goodman MM. Synthesis and biological evaluation of 2beta,3alpha-(substituted phenyl)nortropanes as potential norepinephrine transporter imaging agents. Bioorg Med Chem Lett. 2007 Jun 01; 17(11):3044-7. PMID: 17446069.
      View in: PubMed
    65. Robertson D, Snarey J, Ousley O, Harenski K, Bowman FB, Gilkey R, Kilts CD. An fMRI study of ethical decision making: The neural basis of moral sensitivity to issues of care and justice. Neuropsychologia. 2007; 45:755-766.
    66. Duncan E, Bosheven W, Harenski K, Fallios A, Tracy H, Jovanovic T, Hu X, Drexler K, Kilts C. An fMRI study of the interaction of stress and cocaine cues on craving. Am J Addiction. 2007; 16(3):174-182.
    67. Robertson D, Snarey J, Ousley O, Harenski K, DuBois Bowman F, Gilkey R, Kilts C. The neural processing of moral sensitivity to issues of justice and care. Neuropsychologia. 2007 Mar 02; 45(4):755-66. PMID: 17174987.
      View in: PubMed
    68. Westen D, Blagov PS, Harenski K, Kilts C, Hamann S. Neural bases of motivated reasoning: an FMRI study of emotional constraints on partisan political judgment in the 2004 U.S. Presidential election. J Cogn Neurosci. 2006 Nov; 18(11):1947-58. PMID: 17069484.
      View in: PubMed
    69. Zeng F, Jarkas N, Owens MJ, Kilts CD, Nemeroff CB, Goodman MM. Synthesis and monoamine transporter affinity of front bridged tricyclic 3beta-(4'-halo or 4'-methyl)phenyltropanes bearing methylene or carbomethoxymethylene on the bridge to the 2beta-position. Bioorg Med Chem Lett. 2006 Sep 01; 16(17):4661-3. PMID: 16784855.
      View in: PubMed
    70. Kilts CD, Kelsey JE, Knight B, Ely TD, Bowman FD, Gross RE, Selvig A, Gordon A, Newport DJ, Nemeroff CB. The neural correlates of social anxiety disorder and response to pharmacotherapy. Neuropsychopharmacology. 2006 Oct; 31(10):2243-53. PMID: 16525417.
      View in: PubMed
    71. Plisson C, Jarkas N, McConathy J, Voll RJ, Votaw J, Williams L, Howell LL, Kilts CD, Goodman MM. Evaluation of carbon-11-labeled 2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)phenyl]nortropane as a potential radioligand for imaging the serotonin transporter by PET. J Med Chem. 2006 Feb 09; 49(3):942-6. PMID: 16451060.
      View in: PubMed
    72. Zeng F, Jarkas N, Owens MJ, Kilts CD, Nemeroff CB, Godman MM. Synthesis and monoamine transporter affinity of front bridged tricyclic 3ß-(4’-halo or 4’-methyl)phenyltropanes bearing methylene or carbomethoxymethylene on the bridge to the 2ß -position. Bioorganic Medicinal Chem Letters. 2006; (16):4661-4663.
    73. Westen D, Blagov P, Harenski K, Kilts C, Hamann S. Neural basis of motivated reasoning: An fMRI study of emotional constraints on partisan political judgment in the 2004 U.S. J Cognit Neurosci. 2006; (18):1947-1958.
    74. VanNess SH, Owens MJ, Kilts CD. The variable number of tandem repeats element in DAT1 regulates in vitro dopamine transporter density. BMC Genet. 2005 Nov 27; 6:55. PMID: 16309561.
      View in: PubMed
    75. Nemeroff CB, Lieberman JA, Weiden PJ, Harvey PD, Newcomer JW, Schatzberg AF, Kilts CD, Daniel DG. From clinical research to clinical practice: a 4-year review of ziprasidone. CNS Spectr. 2005 Nov; 10(11 Suppl 17):1-20. PMID: 16381088.
      View in: PubMed
    76. McConathy J, Owens MJ, Kilts CD, Malveaux EJ, Votaw JR, Nemeroff CB, Goodman MM. Synthesis and biological evaluation of trans-3-phenyl-1-indanamines as potential norepinephrine transporter imaging agents. Nucl Med Biol. 2005 Aug; 32(6):593-605. PMID: 16026706.
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    77. Jarkas N, Votaw JR, Voll RJ, Williams L, Camp VM, Owens MJ, Purselle DC, Bremner JD, Kilts CD, Nemeroff CB, Goodman MM. Carbon-11 HOMADAM: a novel PET radiotracer for imaging serotonin transporters. Nucl Med Biol. 2005 Apr; 32(3):211-24. PMID: 15820756.
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    78. Jarkas N, McConathy J, Votaw JR, Voll RJ, Malveaux E, Camp VM, Williams L, Goodman RR, Kilts CD, Goodman MM. Synthesis and characterization of EADAM: a selective radioligand for mapping the brain serotonin transporters by positron emission tomography. Nucl Med Biol. 2005 Jan; 32(1):75-86. PMID: 15691664.
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    79. Jarkas N, McConathy J, Votaw JR, Voll RJ, Mallveaux E, Camp VM, Williams L, Goodman RR, Kilts CD, Goodman MM. Synthesis and characterization of EADAM: A selective radioligand for mapping the brain serotonin transporter by positron emission tomography. Nuc Med Biol. 2005; (32):75-86.
    80. Kilts C, VanNess SH, Owens MJ. The variable number of tandem repeats (VNTR) element in DAT1 regulates dopamine transporter density. BMC Genetics. 2005; (6):55-66.
    81. Schweitzer JB, Lee DO, Hanford RB, Zink CF, Ely TD, Tagamets MA, Hoffman JM, Grafton ST, Kilts CD. Effect of methylphenidate on executive functioning in adults with attention-deficit/hyperactivity disorder: normalization of behavior but not related brain activity. Biol Psychiatry. 2004 Oct 15; 56(8):597-606. PMID: 15476690.
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    82. Rilling JK, Winslow JT, Kilts CD. The neural correlates of mate competition in dominant male rhesus macaques. Biol Psychiatry. 2004 Sep 01; 56(5):364-75. PMID: 15336519.
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    83. McConathy J, Owens MJ, Kilts CD, Malveaux EJ, Camp VM, Votaw JR, Nemeroff CB, Goodman MM. Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the norepinephrine transporter. Nucl Med Biol. 2004 Aug; 31(6):705-18. PMID: 15246361.
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    84. Kilts CD, Gross RE, Ely TD, Drexler KP. The neural correlates of cue-induced craving in cocaine-dependent women. Am J Psychiatry. 2004 Feb; 161(2):233-41. PMID: 14754771.
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    85. Kilts CD. Understanding psychiatric disorders through functional brain imaging. Psychopharmacol Bull. 2004; 38(1):21-4. PMID: 15278014.
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    86. Rilling JK, Winslow JT, Kilts CD. The neural correlates of mate competition in dominant male rhesus monkeys. Biol Psychiatry. 2004; (56):364-375.
    87. Kilts CD, Gross RE, Ely TD, Drexler KPG. The neural correlates of drug cue-induced craving in cocaine-dependent women. Am J Psychiatry. 2004; (161):233-241.
    88. Leonard SK, Anderson CM, Lachowicz JE, Schulz DW, Kilts CD, Mailman RB. Amygdaloid D1 receptors are not linked to stimulation of adenylate cyclase. Synapse. 2003 Dec 15; 50(4):320-33. PMID: 14556237.
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    89. DuBois Bowman F, Kilts C. Modeling intra-subject correlation among repeated scans in positron emission tomography (PET) neuroimaging data. Hum Brain Mapp. 2003 Oct; 20(2):59-70. PMID: 14505332.
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    90. Davis MR, Votaw JR, Bremner JD, Byas-Smith MG, Faber TL, Voll RJ, Hoffman JM, Grafton ST, Kilts CD, Goodman MM. Initial human PET imaging studies with the dopamine transporter ligand 18F-FECNT. J Nucl Med. 2003 Jun; 44(6):855-61. PMID: 12791810.
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    91. Schweitzer JB, Lee DO, Hanford RB, Tagamets MA, Hoffman JM, Grafton ST, Kilts CD. A positron emission tomography study of methylphenidate in adults with ADHD: alterations in resting blood flow and predicting treatment response. Neuropsychopharmacology. 2003 May; 28(5):967-73. PMID: 12700698.
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    92. Goodman MM, Chen P, Plisson C, Martarello L, Galt J, Votaw JR, Kilts CD, Malveaux G, Camp VM, Shi B, Ely TD, Howell L, McConathy J, Nemeroff CB. Synthesis and characterization of iodine-123 labeled 2beta-carbomethoxy-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane. A ligand for in vivo imaging of serotonin transporters by single-photon-emission tomography. J Med Chem. 2003 Mar 13; 46(6):925-35. PMID: 12620070.
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    93. Kilts CD, Egan G, Gideon DA, Ely TD, Hoffman JM. Dissociable neural pathways are involved in the recognition of emotion in static and dynamic facial expressions. Neuroimage. 2003 Jan; 18(1):156-68. PMID: 12507452.
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    94. Kilts C. In vivo neuroimaging correlates of the efficacy of paroxetine in the treatment of mood and anxiety disorders. Psychopharmacol Bull. 2003; 37 Suppl 1:19-28. PMID: 14566198.
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    95. Kilts CD. Potential new drug delivery systems for antidepressants: an overview. J Clin Psychiatry. 2003; 64 Suppl 18:31-3. PMID: 14700453.
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    96. Leonard SK, Petitto JM, Anderson CM, Mooney DH, Lachowicz JE, Schulz DW, Kilts CD, Mailman RB. D1 dopamine receptors in the amygdala exhibit unique properties. Ann NY Acad Sci. 2003; (985):536-539.
    97. Rilling J, Gutman D, Zeh T, Pagnoni G, Berns G, Kilts C. A neural basis for social cooperation. Neuron. 2002 Jul 18; 35(2):395-405. PMID: 12160756.
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    98. Votaw JR, Howell LL, Martarello L, Hoffman JM, Kilts CD, Lindsey KP, Goodman MM. Measurement of dopamine transporter occupancy for multiple injections of cocaine using a single injection of [F-18]FECNT. Synapse. 2002 Jun 15; 44(4):203-10. PMID: 11984856.
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    99. Binder EB, Gross RE, Nemeroff CB, Kilts CD. Effects of neurotensin receptor antagonism on latent inhibition in Sprague-Dawley rats. Psychopharmacology (Berl). 2002 May; 161(3):288-95. PMID: 12021832.
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    100. Hamann SB, Ely TD, Hoffman JM, Kilts CD. Ecstasy and agony: activation of the human amygdala in positive and negative emotion. Psychol Sci. 2002 Mar; 13(2):135-41. PMID: 11933997.
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    101. Derado, G, Bowman FD, Ely TD. Evaluating functional autocorrelation within spatially distributed neural processing networks. Statistics and Its Interface. 1:45-57.
    102. Wade AG, Schlaepfer TE, Andersen HF. Clinical milestones predict symptom remission over 6-months and choice of treatment of patients with major depressive disorder (MDD). J Psychiatric Res.
    103. Caceda, R, James GA, Ely TD, Snarey J. Mode of effective connectivity within putative neural networks differentiates moral cognitions related to care and justice ethics. PLOS ONE. 2(e14730).
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