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Wayne Wahls

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentBiochemistry & Molecular Biology, College of Medicine
DivisionBiochemistry & Molecular Meiosis
AddressB421C Biomedical Research I
325 S. Elm St.
Mail Slot # 516
Little Rock AR 72205
Phone501-686-5787
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wahls WP. NIH's ineffective funding policies. Science. 2017 Jun 16; 356(6343):1132-1133. PMID: 28619908.
      View in: PubMed
    2. Wahls WP. Biases in grant proposal success rates, funding rates and award sizes affect the geographical distribution of funding for biomedical research. PeerJ. 2016; 4:e1917. PMID: 27077009; PMCID: PMC4830231.
    3. Protacio RU, Storey AJ, Davidson MK, Wahls WP. Nonsense codon suppression in fission yeast due to mutations of tRNA(Ser.11) and translation release factor Sup35 (eRF3). Curr Genet. 2015 May; 61(2):165-73. PMID: 25519804; PMCID: PMC4393767.
    4. García P, Paulo E, Gao J, Wahls WP, Ayté J, Lowy E, Hidalgo E. Binding of the transcription factor Atf1 to promoters serves as a barrier to phase nucleosome arrays and avoid cryptic transcription. Nucleic Acids Res. 2014; 42(16):10351-9. PMID: 25122751; PMCID: PMC4176342.
    5. Waldrip ZJ, Byrum SD, Storey AJ, Gao J, Byrd AK, Mackintosh SG, Wahls WP, Taverna SD, Raney KD, Tackett AJ. A CRISPR-based approach for proteomic analysis of a single genomic locus. Epigenetics. 2014 Sep; 9(9):1207-11. PMID: 25147920; PMCID: PMC4169012.
    6. Gao J, Kan F, Wagnon JL, Storey AJ, Protacio RU, Davidson MK, Wahls WP. Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe. Curr Genet. 2014 May; 60(2):109-19. PMID: 24026504; PMCID: PMC3954454.
    7. Gao J, Wagnon JL, Protacio RM, Glazko GV, Beggs M, Raj V, Davidson MK, Wahls WP. A stress-activated, p38 mitogen-activated protein kinase-ATF/CREB pathway regulates posttranscriptional, sequence-dependent decay of target RNAs. Mol Cell Biol. 2013 Aug; 33(15):3026-35. PMID: 23732911; PMCID: PMC3719685.
    8. Wahls WP, Davidson MK. New paradigms for conserved, multifactorial, cis-acting regulation of meiotic recombination. Nucleic Acids Res. 2012 Nov 01; 40(20):9983-9. PMID: 22904082; PMCID: PMC3488224.
    9. Wahls WP, Davidson MK. DNA sequence-mediated, evolutionarily rapid redistribution of meiotic recombination hotspots. Genetics. 2011 Nov; 189(3):685-94. PMID: 22084420; PMCID: PMC3213376.
    10. Kan F, Davidson MK, Wahls WP. Meiotic recombination protein Rec12: functional conservation, crossover homeostasis and early crossover/non-crossover decision. Nucleic Acids Res. 2011 Mar; 39(4):1460-72. PMID: 21030440; PMCID: PMC3045620.
    11. Wahls WP, Davidson MK. Discrete DNA sites regulate global distribution of meiotic recombination. Trends Genet. 2010 May; 26(5):202-8. PMID: 20381894; PMCID: PMC2860662.
    12. Misty, J., Wood, V., Finn, R. D., Wahls WP. Atf1 osmotic stress activation (OSA) domain (founding member, domain organization, alignments, curation and models, trees, species). The Pfam protein families database. 2010.
    13. Misty, J., Wood, V., Finn, R. D., Wahls WP. Atf1 Homologous recombination repression *HRR) domain (founding member, domain, domain organization, alignments, curation and models, trees, species). The Pfam protein families database. 2010.
    14. Gao J, Davidson MK, Wahls WP. Phosphorylation-independent regulation of Atf1-promoted meiotic recombination by stress-activated, p38 kinase Spc1 of fission yeast. PLoS One. 2009; 4(5):e5533. PMID: 19436749; PMCID: PMC2677671.
    15. Gao J, Davidson MK, Wahls WP. Phosphorylation-independent regualtion of Atf1-promoted meiotic recombination by stress-activated p38 kinase Spc1 of fission yeast. PLoS One. 2009; 5(e5533).
    16. Wahls WP, Davidson MK. Low-copy episomal vector pFY20 and high-saturation coverage genomic libraries for the fission yeast Schizosaccharomyces pombe. Yeast. 2008 Sep; 25(9):643-50. PMID: 18613214; PMCID: PMC3119484.
    17. Wahls WP, Siegel ER, Davidson MK. Meiotic recombination hotspots of fission yeast are directed to loci that express non-coding RNA. PLoS One. 2008 Aug 06; 3(8):e2887. PMID: 18682829; PMCID: PMC2483352.
    18. Gao J, Davidson MK, Wahls WP. Distinct regions of ATF/CREB proteins Atf1 and Pcr1 control recombination hotspot ade6-M26 and the osmotic stress response. Nucleic Acids Res. 2008 May; 36(9):2838-51. PMID: 18375981; PMCID: PMC2396409.
    19. DeWall KM, Davidson MK, Sharif WD, Wiley CA, Wahls WP. A DNA binding motif of meiotic recombinase Rec12 (Spo11) defined by essential glycine-202, and persistence of Rec12 protein after completion of recombination. Gene. 2005 Aug 15; 356:77-84. PMID: 16009511; PMCID: PMC3119478.
    20. Wu H, Gao J, Sharif WD, Davidson MK, Wahls WP. Purification, folding, and characterization of Rec12 (Spo11) meiotic recombinase of fission yeast. Protein Expr Purif. 2004 Nov; 38(1):136-44. PMID: 15477092; PMCID: PMC3127416.
    21. Davidson MK, Shandilya HK, Hirota K, Ohta K, Wahls WP. Atf1-Pcr1-M26 complex links stress-activated MAPK and cAMP-dependent protein kinase pathways via chromatin remodeling of cgs2+. J Biol Chem. 2004 Dec 03; 279(49):50857-63. PMID: 15448137; PMCID: PMC3141327.
    22. Davidson MK, Young NP, Glick GG, Wahls WP. Meiotic chromosome segregation mutants identified by insertional mutagenesis of fission yeast Schizosaccharomyces pombe; tandem-repeat, single-site integrations. Nucleic Acids Res. 2004; 32(14):4400-10. PMID: 15316103; PMCID: PMC514387.
    23. Yamada T, Mizuno K, Hirota K, Kon N, Wahls WP, Hartsuiker E, Murofushi H, Shibata T, Ohta K. Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot. EMBO J. 2004 Apr 21; 23(8):1792-803. PMID: 14988732; PMCID: PMC394230.
    24. Sharif WD, Glick GG, Davidson MK, Wahls WP. Distinct functions of S. pombe Rec12 (Spo11) protein and Rec12-dependent crossover recombination (chiasmata) in meiosis I; and a requirement for Rec12 in meiosis II. Cell Chromosome. 2002 Sep 19; 1(1):1. PMID: 12437782.
      View in: PubMed
    25. Sharif WD, Glick GG, Davidson MK, Wahls WP. Distinct functions of S. pombe Rec12 (Spo11) protein and Rec12-dependent crossover recombination (chiasmata) in meiosis I; and a requirement for Rec12 in meiosis II. Cell Chromosome. 2002; 1(1):1 - .
    26. Krawchuk MD, Wahls WP. High-efficiency gene targeting in Schizosaccharomyces pombe using a modular, PCR-based approach with long tracts of flanking homology. Yeast. 1999 Sep 30; 15(13):1419-27. PMID: 10509024; PMCID: PMC3190138.
    27. Krawchuk MD, DeVeaux LC, Wahls WP. Meiotic chromosome dynamics dependent upon the rec8(+), rec10(+) and rec11(+) genes of the fission yeast Schizosaccharomyces pombe. Genetics. 1999 Sep; 153(1):57-68. PMID: 10471700; PMCID: PMC1460733.
    28. Krawchuk MD, Wahls WP. Centromere mapping functions for aneuploid meiotic products: Analysis of rec8, rec10 and rec11 mutants of the fission yeast Schizosaccharomyces pombe. Genetics. 1999 Sep; 153(1):49-55. PMID: 10471699; PMCID: PMC1460729.
    29. Kon N, Schroeder SC, Krawchuk MD, Wahls WP. Regulation of the Mts1-Mts2-dependent ade6-M26 meiotic recombination hot spot and developmental decisions by the Spc1 mitogen-activated protein kinase of fission yeast. Mol Cell Biol. 1998 Dec; 18(12):7575-83. PMID: 9819443; PMCID: PMC109338.
    30. Wahls WP, Moore PD. Recombination hotspot activity of hypervariable minisatellite DNA requires minisatellite DNA binding proteins. Somat Cell Mol Genet. 1998 Jan; 24(1):41-51. PMID: 9776980; PMCID: PMC3151739.
    31. Wahls WP. Meiotic recombination hotspots: shaping the genome and insights into hypervariable minisatellite DNA change. Curr Top Dev Biol. 1998; 37:37-75. PMID: 9352183; PMCID: PMC3151733.
    32. Kon N, Krawchuk MD, Warren BG, Smith GR, Wahls WP. Transcription factor Mts1/Mts2 (Atf1/Pcr1, Gad7/Pcr1) activates the M26 meiotic recombination hotspot in Schizosaccharomyces pombe. Proc Natl Acad Sci U S A. 1997 Dec 09; 94(25):13765-70. PMID: 9391101; PMCID: PMC28381.
    33. Li YF, Numata M, Wahls WP, Smith GR. Region-specific meiotic recombination in Schizosaccharomyces pombe: the rec11 gene. Mol Microbiol. 1997 Mar; 23(5):869-78. PMID: 9076725.
      View in: PubMed
    34. Wahls WP, Smith GR. A heteromeric protein that binds to a meiotic homologous recombination hot spot: correlation of binding and hot spot activity. Genes Dev. 1994 Jul 15; 8(14):1693-702. PMID: 7958849.
      View in: PubMed
    35. Wahls WP. RNA associated with a heterodimeric protein that activates a meiotic homologous recombination hot spot: RL/RT/PCR strategy for cloning any unknown RNA or DNA. PCR Methods Appl. 1994 Apr; 3(5):272-7. PMID: 7518718.
      View in: PubMed
    36. Wahls WP, Song JM, Smith GR. Single-stranded DNA binding activity of C1-tetrahydrofolate synthase enzymes. J Biol Chem. 1993 Nov 15; 268(32):23792-8. PMID: 8226914.
      View in: PubMed
    37. Wahls WP, Swenson G, Moore PD. Two hypervariable minisatellite DNA binding proteins. Nucleic Acids Res. 1991 Jun 25; 19(12):3269-74. PMID: 2062643; PMCID: PMC328321.
    38. Wahls WP, Moore PD. Homologous recombination enhancement conferred by the Z-DNA motif d(TG)30 is abrogated by simian virus 40 T antigen binding to adjacent DNA sequences. Mol Cell Biol. 1990 Feb; 10(2):794-800. PMID: 2153923; PMCID: PMC360880.
    39. Wahls WP, Wallace LJ, Moore PD. The Z-DNA motif d(TG)30 promotes reception of information during gene conversion events while stimulating homologous recombination in human cells in culture. Mol Cell Biol. 1990 Feb; 10(2):785-93. PMID: 2405255; PMCID: PMC360879.
    40. Wahls WP, Wallace LJ, Moore PD. Hypervariable minisatellite DNA is a hotspot for homologous recombination in human cells. Cell. 1990 Jan 12; 60(1):95-103. PMID: 2295091.
      View in: PubMed
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