Donald Mock
Title | Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Biochemistry & Molecular Biology, College of Medicine |
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Address | 6R08A Barton Research 4301 W. Markham Mail Slot # 516 Little Rock AR 72205
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Phone | 501-526-4207 |
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vCard | Download vCard |
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Title | Adjunct Assistant Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Dietetics And Nutrition, College of Health Professions |
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Affiliation Director of Pilot grant program in PTC function; codirector of mock study section in BERD function
Research UL1TR003107 (JAMES, LAURA P)Jul 1, 2019 - Jun 30, 2024 NIH Expanding Translational Research in Arkansas Role: Co-Investigator |
| U54TR001629 (JAMES, LAURA P)Sep 26, 2017 - Aug 31, 2019 NIH Expanding Translational Research in Arkansas Role: Co-Investigator |
| 117-1003725 (MOCK, DONALD M)Jul 1, 2015 - Jun 30, 2017 UAMS College of Medicine Mock-Univ of Laval Account Role: Principal Investigator |
| P01HL046925 (MOCK, DONALD)Jul 1, 2014 - Jun 30, 2018 NIH/Nat. Heart, Lung & Blood Institute - Pass Through: University of Iowa Neonatal Anemia and Thrombocytopenia: Pathophysiology and Treatment Role: Principal Investigator |
| Biotin Analysis (MOCK, DONALD M)Oct 28, 2009 Universite' Laval Universite' Laval - Biotin Analysis Role: Principal Investigator |
| R01DK079892 (MOCK, DONALD M)Sep 1, 2009 - Aug 31, 2014 NIH Biotin Status in Pregnancy Role: Principal Investigator |
| w000082478 (MOCK, DONALD M)Jul 1, 2007 - Jun 30, 2011 Thrasher Foundation - Pass Through: University of Iowa 30579 UI RBC Recovery & Survival FollowingTransfusion in Infants Role: Principal Investigator |
| R01HL060887 (MOCK, DONALD M)Jul 10, 1998 - Jun 30, 2000 NIH RECEPTOR BINDING DETERMINES ERYTHROPOIETIN DISPOSITION Role: Principal Investigator |
| S15MH053640 (MOCK, DONALD M)Aug 1, 1994 - Jul 31, 1995 NIH SMALL INSTRUMENTATION GRANT Role: Principal Investigator |
| R01HD027061 (MOCK, DONALD M)Jul 15, 1990 - Jun 30, 1994 NIH BIOTIN REQUIREMENTS OF INFANTS Role: Principal Investigator |
| K04DK001810 (MOCK, DONALD M)Jul 1, 1987 - Jun 30, 1992 NIH HUMAN REQUIREMENT FOR BIOTIN Role: Principal Investigator |
| R37DK036823 (MOCK, DONALD M)Jul 1, 1985 - Jan 31, 2014 NIH Aspects of Biotin Nutrition Role: Principal Investigator |
| R01DK036823 (MOCK, DONALD M)Jul 1, 1985 - Mar 31, 2002 NIH INDICES OF BIOTIN NUTRITION Role: Principal Investigator |
| R01AM036823 (MOCK, DONALD M)Jul 1, 1985 - Jun 30, 1988 NIH INDICES OF BIOTIN NUTRITION Role: Principal Investigator |
| R23HD021320 (MOCK, DONALD M)Jun 1, 1985 - Sep 30, 1987 NIH GROWTH RETARDATION IN FRUCTOSE INTOLEARANCE Role: Principal Investigator |
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Mock DM, Stowell SR, Franco RS, Kyosseva SV, Nalbant D, Schmidt RL, Cress GA, Strauss RG, Cancelas JA, von Goetz M, North AK, Widness JA. Antibodies against biotin-labeled red blood cells can shorten posttransfusion survival. Transfusion. 2022 04; 62(4):770-782. PMID: 35274303.
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D'Cunha R, Schmidt R, Widness JA, Mock DM, Yan X, Cress GA, Kuruvilla D, Veng-Pedersen P, An G. Target-mediated disposition population pharmacokinetics model of erythropoietin in premature neonates following multiple intravenous and subcutaneous dosing regimens. Eur J Pharm Sci. 2019 Oct 01; 138:105013. PMID: 31340188.
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An G, Schmidt RL, Mock DM, Veng-Pedersen P, Widness JA. Overlooked Issues on Pharmacokinetics Data Interpretation of Protein Drugs-a Case Example of Erythropoietin. AAPS J. 2018 11 26; 21(1):6. PMID: 30478521.
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Mock DM, Nalbant D, Kyosseva SV, Schmidt RL, An G, Matthews NI, Vlaar APJ, van Bruggen R, de Korte D, Strauss RG, Cancelas JA, Franco RS, Veng-Pedersen P, Widness JA. Development, validation, and potential applications of biotinylated red blood cells for posttransfusion kinetics and other physiological studies: evidenced-based analysis and recommendations. Transfusion. 2018 08; 58(8):2068-2081. PMID: 29770455.
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Nalbant D, Cancelas JA, Mock DM, Kyosseva SV, Schmidt RL, Cress GA, Zimmerman MB, Strauss RG, Widness JA. In premature infants there is no decrease in 24-hour posttransfusion allogeneic red blood cell recovery after 42 days of storage. Transfusion. 2018 02; 58(2):352-358. PMID: 29193118.
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Mock DM. Biotin: From Nutrition to Therapeutics. J Nutr. 2017 08; 147(8):1487-1492. PMID: 28701385.
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Schmidt RL, Mock DM, Franco RS, Cohen RM, North AK, Cancelas JA, Geisen C, Strauss RG, Vlaar AP, Nalbant D, Widness JA. Antibodies to biotinylated red blood cells in adults and infants: improved detection, partial characterization, and dependence on red blood cell-biotin dose. Transfusion. 2017 06; 57(6):1488-1496. PMID: 28261808.
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An G, Ohls RK, Christensen RD, Widness JA, Mock DM, Veng-Pedersen P. Population Pharmacokinetics of Darbepoetin in Infants Following Single Intravenous and Subcutaneous Dosing. J Pharm Sci. 2017 06; 106(6):1644-1649. PMID: 28189627.
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Kuruvilla DJ, Widness JA, Nalbant D, Schmidt RL, Mock DM, An G, Veng-Pedersen P. Estimation of adult and neonatal RBC lifespans in anemic neonates using RBCs labeled at several discrete biotin densities. Pediatr Res. 2017 Jun; 81(6):905-910. PMID: 28099421.
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Balasubramaniam S, Lewis B, Mock DM, Said HM, Tarailo-Graovac M, Mattman A, van Karnebeek CD, Thorburn DR, Rodenburg RJ, Christodoulou J. Erratum: Leigh-Like Syndrome Due to Homoplasmic m.8993T>G Variant with Hypocitrullinemia and Unusual Biochemical Features Suggestive of Multiple Carboxylase Deficiency (MCD). JIMD Rep. 2017; 33:111. PMID: 29076057.
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Balasubramaniam S, Lewis B, Mock DM, Said HM, Tarailo-Graovac M, Mattman A, van Karnebeek CD, Thorburn DR, Rodenburg RJ, Christodoulou J. Leigh-Like Syndrome Due to Homoplasmic m.8993T>G Variant with Hypocitrullinemia and Unusual Biochemical Features Suggestive of Multiple Carboxylase Deficiency (MCD). JIMD Rep. 2017; 33:99-107. PMID: 27450367.
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An G, Widness JA, Mock DM, Veng-Pedersen P. A Novel Physiology-Based Mathematical Model to Estimate Red Blood Cell Lifespan in Different Human Age Groups. AAPS J. 2016 09; 18(5):1182-1191. PMID: 27215601.
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Peters AL, Beuger B, Mock DM, Widness JA, de Korte D, Juffermans NP, Vlaar AP, van Bruggen R. Clearance of stored red blood cells is not increased compared with fresh red blood cells in a human endotoxemia model. Transfusion. 2016 06; 56(6):1362-9. PMID: 27040455.
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Shrestha RP, Horowitz J, Hollot CV, Germain MJ, Widness JA, Mock DM, Veng-Pedersen P, Chait Y. Models for the red blood cell lifespan. J Pharmacokinet Pharmacodyn. 2016 06; 43(3):259-74. PMID: 27039311.
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Peyro Saint Paul L, Debruyne D, Bernard D, Mock DM, Defer GL. Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis. Expert Opin Drug Metab Toxicol. 2016; 12(3):327-44. PMID: 26699811.
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Kuruvilla DJ, Widness JA, Nalbant D, Schmidt RL, Mock DM, Veng-Pedersen P. A Mass Balance-Based Semiparametric Approach to Evaluate Neonatal Erythropoiesis. AAPS J. 2016 Jan; 18(1):187-95. PMID: 26502725.
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Widness JA, Kuruvilla DJ, Mock DM, Matthews NI, Nalbant D, Cress GA, Schmidt RL, Strauss RG, Zimmerman MB, Veng-Pedersen P. Autologous Infant and Allogeneic Adult Red Cells Demonstrate Similar Concurrent Post-Transfusion Survival in Very Low Birth Weight Neonates. J Pediatr. 2015 Nov; 167(5):1001-6. PMID: 26363547.
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Sedel F, Bernard D, Mock DM, Tourbah A. Targeting demyelination and virtual hypoxia with high-dose biotin as a treatment for progressive multiple sclerosis. Neuropharmacology. 2016 Nov; 110(Pt B):644-653. PMID: 26327679.
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Kuruvilla DJ, Widness JA, Nalbant D, Schmidt RL, Mock DM, Veng-Pedersen P. A Method to Evaluate Fetal Erythropoiesis from Postnatal Survival of Fetal RBCs. AAPS J. 2015 Sep; 17(5):1246-54. PMID: 26017162.
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Bogusiewicz A, Boysen G, Mock DM. In HepG2 cells, coexisting carnitine deficiency masks important indicators of marginal biotin deficiency. J Nutr. 2015 Jan; 145(1):32-40. PMID: 25527659.
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Mock DM. Adequate intake of biotin in pregnancy: why bother? J Nutr. 2014 Dec; 144(12):1885-6. PMID: 25320191.
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Mock DM, Widness JA, Veng-Pedersen P, Strauss RG, Cancelas JA, Cohen RM, Lindsell CJ, Franco RS. Measurement of posttransfusion red cell survival with the biotin label. Transfus Med Rev. 2014 Jul; 28(3):114-25. PMID: 24969019.
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Widness JA, Nalbant D, Matthews NI, Strauss RG, Schmidt RL, Cress GA, Zimmerman MB, Mock DM. Tracking donor RBC survival in premature infants: agreement of multiple populations of biotin-labeled RBCs with Kidd antigen-mismatched RBCs. Pediatr Res. 2013 Dec; 74(6):689-97. PMID: 24108188.
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Nalbant D, Bhandary P, Matthews NI, Schmidt RL, Bogusiewicz A, Cress GA, Zimmerman MB, Strauss RG, Mock DM, Widness JA. Comparison of multiple red cell volume methods performed concurrently in premature infants following allogeneic transfusion. Pediatr Res. 2013 Nov; 74(5):592-600. PMID: 24088873.
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Moretti H, Matthews NI, Mock DM. Biotin Deficiency as a Target for Treating Restless Legs Syndrome in Chronic Dialysis Patients. Journal of Nephrology & Therapeutics. 2013.
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Yossa R, Sarker P, Mock DM, Vandenberg G. Dietary biotin requirement for growth of zebrafish Danio rerio. Aquaculture Research. 2013; Hamilton-Buchanan:1-11.
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Bogusiewicz A, Horvath TD, Stratton SL, Mock DM, Boysen G. Measurement of acylcarnitine substrate to product ratios specific to biotin-dependent carboxylases offers a combination of indicators of biotin status in humans. J Nutr. 2012 Sep; 142(9):1621-5. PMID: 22833654.
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Mock DM, Widness JA, Strauss RG, Franco RS. Posttransfusion red blood cell (RBC) survival determined using biotin-labeled RBCs has distinct advantages over labeling with (51) Cr. Transfusion. 2012 Jul; 52(7):1596-8. PMID: 22780899.
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Mock DM, Matthews NI, Zhu S, Strauss RG, Schmidt RL, Zimmerman MB, Nalbant D, Freise KJ, Saleh M, Veng-Pedersen P, Widness JA. Comparison of red blood cell survival in sheep determined using red blood cells labeled with either biotin at multiple densities or [14C]cyanate: validation of a model to study human physiology and disease. Transfusion. 2012 May; 52(5):963-73. PMID: 22229348.
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Bhandary P, Nalbant D, Schmidt R, Cress G, Mock DM. Hemogobin switch in cord blood cells occurs with decreasing fetal hemoglobin protein but with no decrease in fetal hemoglobin positive (HbF+) cells. Society for Pediatric Research Meeting. 2012.
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Stratton SL, Henrich CL, Matthews NI, Bogusiewicz A, Dawson AM, Horvath TD, Owen SN, Boysen G, Moran JH, Mock DM. Marginal biotin deficiency can be induced experimentally in humans using a cost-effective outpatient design. J Nutr. 2012 Jan; 142(1):22-6. PMID: 22157538.
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Mock DM, Lankford GL, Matthews NI, Burmeister LF, Kahn D, Widness JA, Strauss RG. Accelerated removal of antibody-coated red blood cells from the circulation is accurately tracked by a biotin label. Transfusion. 2012 May; 52(5):1097-105. PMID: 22023312.
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Mock DM, Stratton SL, Horvath TD, Bogusiewicz A, Matthews NI, Henrich CL, Dawson AM, Spencer HJ, Owen SN, Boysen G, Moran JH. Urinary excretion of 3-hydroxyisovaleric acid and 3-hydroxyisovaleryl carnitine increases in response to a leucine challenge in marginally biotin-deficient humans. J Nutr. 2011 Nov; 141(11):1925-30. PMID: 21918059.
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Proskurnin MA, Zhidkova TV, Volkov DS, Sarimollaoglu M, Galanzha EI, Mock D, Nedosekin DA, Zharov VP. In vivo multispectral photoacoustic and photothermal flow cytometry with multicolor dyes: a potential for real-time assessment of circulation, dye-cell interaction, and blood volume. Cytometry A. 2011 Oct; 79(10):834-47. PMID: 21905207.
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Horvath TD, Matthews NI, Stratton SL, Mock DM, Boysen G. Measurement of 3-hydroxyisovaleric acid in urine from marginally biotin-deficient humans by UPLC-MS/MS. Anal Bioanal Chem. 2011 Nov; 401(9):2805-10. PMID: 21892638.
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Mock DM, Horvath T, Stratton S, Bogusiewicz A, Moran J. Urinary excretin of 30hydroxyisovaleryl carnitine (3HIAC) in response to a leucine load increases in marginal biotin deficiency. EB 2011. 2011.
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Stratton S, Horvath T, Owen S, Moran J, Mock DM. The relationship between fetal biotin status and cleft palate in a single pair of fraternal twins. EB 2011. 2011.
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Stratton SL, Horvath TD, Bogusiewicz A, Matthews NI, Henrich CL, Spencer HJ, Moran JH, Mock DM. Urinary excretion of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans. J Nutr. 2011 Mar; 141(3):353-8. PMID: 21248194.
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Bhandary P, Nalbant D, Schmidt R, Cress G, Matthews NI, Mock DM, Widness J. Higher fetal hemoglobin expression in intact cord red blood cells (RBCs) measured by flow cytometry versus by HPLC. Perinatal & Development Medicine Symposium. 2011.
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Mock DM, Matthews NI, Zhu S, Burmeister LF, Zimmerman MB, Strauss RG, Schmidt RL, Nalbant D, Cress GA, Widness JA. Red blood cell (RBC) volume can be independently determined in vivo in humans using RBCs labeled at different densities of biotin. Transfusion. 2011 Jan; 51(1):148-57. PMID: 20630041.
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Nalbant D, Matthews NI, Bhandary P, Bogusiewicz A, Schmidt R, Mock DM, Widness J. Red cell volume can be measured in very low birth weight infants using dilution method of hemoglobin f cells by allogentic adult red blood cell transfusion. The Midwest Society for Pediatric Research (MWSPR). 2011.
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Widness JA, Matthews NI, Zhu S, Mock DM, Nalbant D, Schmidt RL, Cress GA, Strauss RG. Red cell volume (RBC) volume (RCV) can be determined simultaneously in infants using RBCs labeled at 4 distrinct biotin densities (BioRBCs). PAS?ASPR Joint Meeting. 2011.
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Mock DM, Matthews NI, Nalbant D, Bogusiewicz A, Schmidt R, Widness J. Transfused Allogeneic Biotinylated Red Cells Accurately Measure Circulating Red Cell Volume in Low Birth Weight Infants. Transfusion. 2011; 51: 110A.
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Bhandary P, Nalbant D, Schmidt R, Cress G, Matthews NI, Mock D, Widness J. Fetal hemoglobin expression in intact cord red blood cells measured by flow cytometry versus by HPLC during 24-41 weeks post-menustrual age. The Midwest Society for Pediatric Research (MWSPR). 2011.
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Bhandary P, Nalbant D, Schmidt R, Cress G, Matthews NI, Mock DM, Widness J. Hemogobin switch in cord blood cells occurs with decreasing fetal hemoglobin protein but with no decrease in fetal hemoglobin positive (HbF+) cells. Perinatal & Development Medicine Symposium. 2011.
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Mock DM, Matthews NI, Zhu S, Burmeister LF, Zimmerman MB, Strauss RG, Schmidt RL, Nalbant D, Freise KJ, Veng-Pedersen P, Widness JA. Red blood cell (RBC) volume can be independently determined in vivo in the sheep using ovine RBCs labeled at different densities of biotin. Transfusion. 2010 Dec; 50(12):2553-64. PMID: 20561297.
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Mock DM, Matthews NI, Zhu S, Strauss RG, Schmidt RL, Nalbant D, Cress GA, Widness JA. Red blood cell (RBC) survival determined in humans using RBCs labeled at multiple biotin densities. Transfusion. 2011 May; 51(5):1047-57. PMID: 21062290.
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Horvath TD, Stratton SL, Bogusiewicz A, Owen SN, Mock DM, Moran JH. Quantitative measurement of urinary excretion of 3-hydroxyisovaleryl carnitine by LC-MS/MS as an indicator of biotin status in humans. Anal Chem. 2010 Nov 15; 82(22):9543-8. PMID: 21028833.
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Stratton SL, Horvath TD, Bogusiewicz A, Matthews NI, Henrich CL, Spencer HJ, Moran JH, Mock DM. Plasma concentration of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans. Am J Clin Nutr. 2010 Dec; 92(6):1399-405. PMID: 20943794.
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Pindolia K, Jordan M, Guo C, Matthews N, Mock DM, Strovel E, Blitzer M, Wolf B. Development and characterization of a mouse with profound biotinidase deficiency: a biotin-responsive neurocutaneous disorder. Mol Genet Metab. 2011 Feb; 102(2):161-9. PMID: 21051254.
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Horvath TD, Stratton SL, Bogusiewicz A, Pack L, Moran J, Mock DM. Quantitative measurement of plasma 3-hydroxyisovaleryl carnitine by LC-MS/MS as a novel biomarker of biotin status in humans. Anal Chem. 2010 May 15; 82(10):4140-4. PMID: 20397702.
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Widness JA, Strauss RG, Schmidt RL, Nalbant D, Matthews NI, Mock DM. In Vivo Red Cell Survival (RCS) Can Be measured Simultaneously and independently in humans using Erythrocytes Labeled at discrete Biotin Densities. PAS. 2010.
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Rodrigue YN, Sarker PK, Mock DM, Vandenberg GW. Quantifying the dietary biotin requirement and its effect on growt6h, survival, welfare, and reproduction zebrafish. 14th International Symposium on Fish Nutrition and Feeding (ISFNF). 2010.
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Widness JA, Strauss RG, Burmeister LF, Schmidt RL, Nalbant D, Matthews NI, Mock DM. Human red cell volume (RCV) can be measured simultaneously and independently in vivo using red blood cells (RBCs) labeled at multiple biotin densities. 2009.
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Mock DM, Matthews NI, Strauss RG, Burmeister LF, Schmidt R, Widness JA. Red blood cell volume can be independently determined in vitro using sheep and human red blood cells labeled at different densities of biotin. Transfusion. 2009 Jun; 49(6):1178-85. PMID: 19220818.
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Mock DM, Mathews NI, Strauss RG, Burmeister LF, Schmidt R, Widnedss JA. Multiple red cell volumes (RCV) can be determined simultaneously and independently in humans in vivo using red cells (RBCs) labeled at biotin densities. 2009.
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Widness JA, Strauss RG, Bumeister LF, Schmidt RL, Zimmerman MB, Nalbant D, Mathews NI, Mock DM. Red cell volume (RCV) can be measured simultaneously and independently in vivo in humans using erythrocyes labeled at four discrete biotin densities. 2009.
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Mathews NI, Mock DM, Strauss RG, Burmeister LF, Schmidt R, Widness JA. Survival of human red cells (RCS) can be followed using 4 different densities of biotin label. 2009.
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Matthews NI, Mock DM, Strauss RG, Burmeister LF, Schmidt R, Widness JA. Sheep red cell survival (RCS)can be followed using 4 different densities of biotin label. 2009.
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Mock DM, Matthews NI, Strauss RG, Burmeister LF, Schmidt R, Widness JA. Multiple red cell volumes (RCV) can be determined simultaneously and independently in humans in vivo using red cells (RBCs) labeled at biotin densities. 2009.
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Stratton SL, Matthews NI, Bogusiewicz A, Zhu S, Mock DM. Evidence that biotin status is impaired in human pregnancy. 2009.
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Mock DM, Said H. Introduction to "Advances in understanding of the biological role of biotin at the clinical, biochemical, and molecular level". J Nutr. 2009 Jan; 139(1):152-3. PMID: 19056638.
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Mock DM. Marginal biotin deficiency is common in normal human pregnancy and is highly teratogenic in mice. J Nutr. 2009 Jan; 139(1):154-7. PMID: 19056637.
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Bogusiewicz A, Stratton SL, Ellison DA, Mock DM. Biotin accounts for less than half of all biotin and biotin metabolites in the cerebrospinal fluid of children. Am J Clin Nutr. 2008 Nov; 88(5):1291-6. PMID: 18996865.
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Mock DM, Mock NI, Lankford GL, Burmeister LF, Strauss RG, Widness JA. Red cell volume can be accurately determined in sheep using a nonradioactive biotin label. Pediatr Res. 2008 Nov; 64(5):528-32. PMID: 18596580.
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Van Hove JL, Josefsberg S, Freehauf C, Thomas JA, Thuy le P, Barshop BA, Woontner M, Mock DM, Chiang PW, Spector E, Meneses-Morales I, Cervantes-Roldán R, León-Del-Río A. Management of a patient with holocarboxylase synthetase deficiency. Mol Genet Metab. 2008 Dec; 95(4):201-5. PMID: 18974016.
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Mock DM. Evidence that biotin status is impaired in human pregnancy. Arkansas Biotechnical Symposium. 2008.
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Koene S, Kluijtmans LAJ, Wevers R, Mock D, Pasch M, Morava E. Biotin-sensitive 3-methylcrotonylglycinuria in a patient with severe growth delay, ectodermal abnormalities, neonatal progeroid appearance, and developmental delay. Clin Dysmorphol. 2008 Jul; 17(3):195-198. PMID: 18541968.
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Strauss RG, Mock DM, Johnson KJ, Cress GA, Burmeister LF, Zimmerman MB, Bell EF, Rijhsinghani A. A randomized clinical trial comparing immediate versus delayed clamping of the umbilical cord in preterm infants: short-term clinical and laboratory endpoints. Transfusion. 2008 Apr; 48(4):658-65. PMID: 18194383.
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Mock DM, Bogusiewicz A. Biotin-protein bond: instability and structural modification to provide stability for in vivo applications. Methods Mol Biol. 2008; 418:209-20. PMID: 18287661.
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Bogusiewicz A, Stratton SL, Ellison DA, Mock DM. C Distribution of Biotin in Cerebrospinal Fluid of Children: Most of the Biotin is Bound to Protein. 2008.
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Forestiere M, Bogusiewicz A, Mock NI, Veng-Pedersen P, Widness JA, Mock DM. An assay for biotinylated-erythropoietin (bio-EPO) suitable for application in tracer pharmacokinetic studies of Erythropoietin (EPO). 2008.
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Mock NI, Widness JA, Schmidt RL, Mock DM. Human red blood cells (RBCs) labeled at discrete 5 densities can be used to independently determine blood volume in vitro. 2008.
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Stratton SL, Bogusiewicz A, Mock NI, Henrich CL, Wells AM, Mock DM. Marginal Biotin Deficiency Successfully Induced by Avidin Supplementation in an Outpatient Design. 2008.
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Mock DM. Biotin. 2007.
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Sealey W, Mock DM. Biotin. 2007.
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Bogusiewicz A, Ellison DA, Mock DM. Concentration of biotin in cerebrospinal fluid of children is underestimated by avidin-binding assay. 2007; 21(5):A348.
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Mock DM, Stratton SL, Mock NI. Biotin status in pregnancy. 2007; 21(5):A103.
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Stratton SL, Bogusiewicz A, Mock MM, Mock NI, Wells AM, Mock DM. Lymphocyte propionyl-CoA carboxylase and its activation by biotin are sensitive indicators of marginal biotin deficiency in humans. Am J Clin Nutr. 2006 Aug; 84(2):384-8. PMID: 16895887.
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Mock DM. Marginal biotin deficiency is teratogenic in mice and perhaps humans: a review of biotin deficiency during human pregnancy and effects of biotin deficiency on gene expression and enzyme activities in mouse dam and fetus. J Nutr Biochem. 2005 Jul; 16(7):435-7. PMID: 15992686.
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Bell EF, Strauss RG, Widness JA, Mahoney LT, Mock DM, Seward VJ, Cress GA, Johnson KJ, Kromer IJ, Zimmerman MB. Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants. Pediatrics. 2005 Jun; 115(6):1685-91. PMID: 15930233.
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Sealey WM, Stratton SL, Mock DM, Hansen DK. Marginal maternal biotin deficiency in CD-1 mice reduces fetal mass of biotin-dependent carboxylases. J Nutr. 2005 May; 135(5):973-7. PMID: 15867267.
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Bogusiewicz A, Mock NI, Mock DM. A biotin-protein bond with stability in plasma. Anal Biochem. 2005 Feb 01; 337(1):98-102. PMID: 15649381.
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Vlasova TI, Stratton SL, Wells AM, Mock NI, Mock DM. Biotin deficiency reduces expression of SLC19A3, a potential biotin transporter, in leukocytes from human blood. J Nutr. 2005 Jan; 135(1):42-7. PMID: 15623830.
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Mock DM, Mock MM, Bogy CD, Mock NI, Stratton SL. Lymphocyte propionyl-CoA carboxylase (PCC) and activation of PCC by biotin are useful indicators of marginal biotin deficiency in humans. 2005; 19(4):A55.
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Mock DM. Biotin. 2005; 498-506.
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Mock DM. Biotin, Dietary Sources and requirements. 2005; 201-209.
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Mock NI, Mock DM. Biotin labeling at different densities allows detection of several discrete populations of mammalian red blood cells. 2005; 19(4):A208.
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Mock DM. Biotin. 2005; 31-40.
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Staggs CG, Sealey WM, McCabe BJ, Teague AM, Mock DM. Determination of the biotin content of select foods using accurate and sensitive HPLC/avidin binding. J Food Compost Anal. 2004 Dec; 17(6):767-776. PMID: 16648879.
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Staggs CG, Sealey WM, McCabe BJ, Teague AM, Mock DM. Determination of the biotin content of select foods using accurate and sensitive HPLC/avidin binding. J Food Compost Anal. 2004; 17(6):767-776.
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Sealey WM, Teague AM, Stratton SL, Mock DM. Smoking accelerates biotin catabolism in women. Am J Clin Nutr. 2004 Oct; 80(4):932-5. PMID: 15447901.
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Bogusiewicz A, Mock NI, Mock DM. Release of biotin from biotinylated proteins occurs enzymatically and nonenzymatically in human plasma. Anal Biochem. 2004 Aug 15; 331(2):260-6. PMID: 15265731.
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Strauss RG, Mock DM, Widness JA, Johnson K, Cress G, Schmidt RL. Posttransfusion 24-hour recovery and subsequent survival of allogeneic red blood cells in the bloodstream of newborn infants. Transfusion. 2004 Jun; 44(6):871-6. PMID: 15157254.
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Bogusiewicz A, Mock NI, Mock DM. Instability of the biotin-protein bond in human plasma. Anal Biochem. 2004 Apr 15; 327(2):156-61. PMID: 15051531.
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Mock DM, Lankford GL, Widness JA, Burmeister LF, Kahn D, Strauss RG. RBCs labeled at two biotin densities permit simultaneous and repeated measurements of circulating RBC volume. Transfusion. 2004 Mar; 44(3):431-7. PMID: 14996203.
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Mock DM, Henrich-Shell CL, Carnell N, Stumbo P, Mock NI. 3-Hydroxypropionic acid and methylcitric acid are not reliable indicators of marginal biotin deficiency in humans. J Nutr. 2004 Feb; 134(2):317-20. PMID: 14747666.
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Hansen DK, Stratton S, Sealey W, Mock DM. Genetic and reproductive toxicology. 2004; 70(Part A):247.
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Stratton S, Sealey W, Hansen D, Mock DM. maternal biotin deficiency in CD-1 mice decreases the abundance of the biotin-dependent carboxylases in fetal liver. 2004; 18(4):A176.
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Teague A, Sealey W, McCabe-Sellers B, Mock DM. Biotin is stable in frozen foods. 2004; 18(4):A143.
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Vlasova T, Stratton S, Mock DM. . In vivo biotin deficiency and supplementation at a pharmacological dose causes differential expression of cerain biotin-related genes in EBV-transformed lymphocytes (EBVL). 2004; 18(4):A405.
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Bogusiewicz A, Mock N, Mock DM. A new biotin conjugate with improved plasma stability. 2004; 18(4):A173.
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Mock DM, Mock NI, Stewart CW, LaBorde JB, Hansen DK. Marginal biotin deficiency is teratogenic in ICR mice. J Nutr. 2003 Aug; 133(8):2519-25. PMID: 12888630.
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Strauss RG, Mock DM, Johnson K, Mock NI, Cress G, Knosp L, Lobas L, Schmidt RL. Circulating RBC volume, measured with biotinylated RBCs, is superior to the Hct to document the hematologic effects of delayed versus immediate umbilical cord clamping in preterm neonates. Transfusion. 2003 Aug; 43(8):1168-72. PMID: 12869126.
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Mock DM, Mock N, Bogusiewicz A. Investigating the stability of the biotin-protein bond in human plasma. 2003; 17(4):A721.
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Bogusiewicz A, Mock N, Mock DM. Biotinidase is not solely responsible for the release of covalently bound biotin from biotinylated proteins in human plasma. 2003; 17(4):A721.
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Sealey W, Mock DM, Hansen D. Supplementation with biotin in vitro fails to ameliorate biotin deficiency-induced clefting. 2003; 17(4):A720.
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Mock DM, Henrich CL, Carnell N, Mock NI. Indicators of marginal biotin deficiency and repletion in humans: validation of 3-hydroxyisovaleric acid excretion and a leucine challenge. Am J Clin Nutr. 2002 Nov; 76(5):1061-8. PMID: 12399279.
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Mock D, Henrich C, Carnell N, Mock N, Swift L. Lymphocyte propionyl-CoA carboxylase and accumulation of odd-chain fatty acid in plasma and erythrocytes are useful indicators of marginal biotin deficiency small star, filled. J Nutr Biochem. 2002 Aug; 13(8):462. PMID: 12165358.
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Stanley JS, Mock DM, Griffin JB, Zempleni J. Biotin uptake into human peripheral blood mononuclear cells increases early in the cell cycle, increasing carboxylase activities. J Nutr. 2002 Jul; 132(7):1854-9. PMID: 12097659.
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Mock DM, Mock NI. Lymphocyte propionyl-CoA carboxylase is an early and sensitive indicator of biotin deficiency in rats, but urinary excretion of 3-hydroxypropionic acid is not. J Nutr. 2002 Jul; 132(7):1945-50. PMID: 12097674.
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Mardach R, Zempleni J, Wolf B, Cannon MJ, Jennings ML, Cress S, Boylan J, Roth S, Cederbaum S, Mock DM. Biotin dependency due to a defect in biotin transport. J Clin Invest. 2002 Jun; 109(12):1617-23. PMID: 12070309.
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Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr. 2002 Feb; 75(2):295-9. PMID: 11815321.
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Mock NI, Henrich C, Carnell N, Swift L, Mock DM. Lymphocyte propionyl-CoA carboxylase (PCC) and odd-chain fatty acid (FA) in plasma and red cells are useful indicators of marginal biotin deficiency. 2002; 16(4):A270.
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Staggs C, Bogle M, Mock DM. Biotin intake and excretion for children in Arkansas. 2002; 16(4):A614.
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Mock DM, Henrich CL, Mock NI, Swift L. Lymphocyte propionyl-CoA carboxylase and accumulation of odd-chain fatty acid in plasma and erythrocytes are useful indicators of marginal biotin deficiency. J Nutr Biochem. 2002; 13(8):162-470.
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Helm RM, Mock NI, Simpson P, Mock DM. Certain immune markers are not good indicators of mild to moderate biotin deficiency in rats. J Nutr. 2001 Dec; 131(12):3231-6. PMID: 11739872.
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Mock DM, Bell EF, Lankford GL, Widness JA. Hematocrit correlates well with circulating red blood cell volume in very low birth weight infants. Pediatr Res. 2001 Oct; 50(4):525-31. PMID: 11568298.
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Mock DM, Nyalala JO, Raguseo RM. A direct streptavidin-binding assay does not accurately quantitate biotin in human urine. J Nutr. 2001 Aug; 131(8):2208-14. PMID: 11481419.
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Zempleni J, Steven Stanley J, Mock DM. Proliferation of peripheral blood mononuclear cells causes increased expression of the sodium-dependent multivitamin transporter gene and increased uptake of pantothenic acidopen star J Nutr Biochem. 2001 Aug; 12(8):465-473. PMID: 11834205.
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Zempleni J, Steven SJ, Mock DM. Proliferation of peripheral blood mononuclear cells causes increased expression of the sodium-dependent multivitamin transporter gene and increased uptake of pantothenic acidopen star. J Nutr Biochem. 2001; 12(8):465 - 473.
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Zempleni J, Mock DM. Biotin homeostasis during the cell cycle. Nutr Res Rev. 2001 Jun; 14(1):45-64. PMID: 19087416.
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Zempleni J, Helm RM, Mock DM. In vivo biotin supplementation at a pharmacologic dose decreases proliferation rates of human peripheral blood mononuclear cells and cytokine release. J Nutr. 2001 May; 131(5):1479-84. PMID: 11340103.
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Wang KS, Kearns GL, Mock DM. The clearance and metabolism of biotin administered intravenously to pigs in tracer and physiologic amounts is much more rapid than previously appreciated. J Nutr. 2001 Apr; 131(4):1271-8. PMID: 11285337.
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Bell EF, Strauss RG, Widness JA, Mahoney LT, Mock DM, Seward VJ, Kromer IJ, Johnson KJ, Cress GA, Connolly NW, Zimmerman MB. Hematocrit threshold for erythrocyte transfusion in preterm infants. European Society for Pediatric Research. 2001; 49:272.
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Zempleni J, Mock DM. Biotin homeostasis through the cell cycle. 2001; 45-63.
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Zempleni J, Mock DM. The Encyclopaedia of Food Sciences and Nutrition. Biotin (b) Physiology. 2001; 102.
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Bell EF, Strauss RG, Widness JA, Mahoney LT, Mock DM, Seward VJ, Kromer IJ, Johnson KJ, Cress GA, Connolly NW, Zimmerman MB. Hematocrit threshold for erythrocyte transfusion in preterm infants. 2001; 49:272.
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Mock DM. Handbook of Vitamins. Biotin. 2001; 14.
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Zempleni J, Mock DM. Biotin. 2001; 459-466.
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Brace RA, Langendörfer C, Song TB, Mock DM. Red blood cell life span in the ovine fetus. Am J Physiol Regul Integr Comp Physiol. 2000 Oct; 279(4):R1196-204. PMID: 11003984.
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Zempleni J, Mock DM. Proliferation of peripheral blood mononuclear cells increases riboflavin influx. Proc Soc Exp Biol Med. 2000 Oct; 225(1):72-9. PMID: 10998201.
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Widness JA, Lowe LS, Bell EF, Burmeister LF, Mock DM, Kistard JA, Bard H. Adaptive responses during anemia and its correction in lambs. J Appl Physiol (1985). 2000 Apr; 88(4):1397-406. PMID: 10749835.
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Zempleni J, Mock DM. Utilization of biotin in proliferating human lymphocytes. J Nutr. 2000 02; 130(2S Suppl):335S-337S. PMID: 10721900.
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Zempleni J, Mock DM. Marginal biotin deficiency is teratogenic. Proc Soc Exp Biol Med. 2000 Jan; 223(1):14-21. PMID: 10632957.
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Mock DM, Nyalala J, Raguseo RM. Total avidin binding substances (TABS) in urine overestimates biotin despite use of an assay that does not detect the common biotin metabolites. FASEB Meeting. 2000; 14(4):A298.
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Mock DM, Lankford G, Strauss RG, Kahn D, Widness JA. A Method for Determination of Circulating Red Cell Volume (RCV). (Strept)Avidin Biotin Technologies Conference. 2000; 16(5):163-4.
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Mock DM, Lankford G, Strauss RG, Kahn D. A Method for Determination of Red Cell Survival (RCS). (Strept)Avidin Biotin Technologies Conference. 2000; 16(5):181.
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Bell EF, Strauss RG, Widness JA, Mahoney LT, Mock DM, Seward VJ, Kromer IJ, Johnson KJ, Cress GA, Connolly NW, Zimmerman MB. Hematocrit threshold for erythrocyte transfusion in preterm infants. European Society for Pediatric Research. 2000; 47:389A.
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Mardach R, Mock DM, Wolf B, Cress S, Boylan J, Roth S, Cederbaum S. Biotin dependency with normal biotinidase and carboxylase activities. VIII International congress of Inborn Errors of Metabolism. 2000; 23(S1):578-P.
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Mardach R, Zempleni J, Mock DM, Wolf B, Cress S, Boylan J, Roth S, Cederbaum S. A novel mechanism for dysfunction of biotin homeostasis. American Society of Human Genetics Annual Meeting. 2000; 67(S2):1594A.
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Zempleni J, Mock DM. Lymphocytes increase biotin uptake during G1 phase of the cell cycle to increase biotinylation of histones. FASEB Meeting. 2000; 14(4):A243.
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Zempleni J, Mock DM. Chemical Synthesis of Biotinylated Histones and Analysis by SDS-PAGE/Streptavidin-Peroxidase. (Strept)Avidin Biotin Technologies Conference. 2000; 16(5):163.
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Walford RL, Mock D, MacCallum T, Laseter JL. Physiologic changes in humans subjected to severe, selective calorie restriction for two years in biosphere 2: health, aging, and toxicological perspectives. Toxicol Sci. 1999 Dec; 52(2 Suppl):61-5. PMID: 10630592.
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Zempleni J, Mock DM. Chemical synthesis of biotinylated histones and analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis/streptavidin-peroxidase. Arch Biochem Biophys. 1999 Nov 01; 371(1):83-8. PMID: 10525292.
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Cordle DG, Strauss RG, Lankford G, Mock DM. Antibodies provoked by the transfusion of biotin-labeled red cells. Transfusion. 1999 Oct; 39(10):1065-9. PMID: 10532599.
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Zempleni J, Mock DM. Human peripheral blood mononuclear cells: ; Inhibition of biotin transport by reversible competition with pantothenic acid is quantitatively minor. J Nutr Biochem. 1999 Jul; 10(7):427-32. PMID: 15539319.
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Zempleni J, Mock DM. Mitogen-induced proliferation increases biotin uptake into human peripheral blood mononuclear cells. Am J Physiol. 1999 05; 276(5):C1079-84. PMID: 10329955.
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Zempleni J, Mock DM. Biotin biochemistry and human requirements. J Nutr Biochem. 1999 Mar; 10(3):128-38. PMID: 15539280.
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Zempleni J, Mock DM. Bioavailability of biotin given orally to humans in pharmacologic doses. Am J Clin Nutr. 1999 Mar; 69(3):504-8. PMID: 10075337.
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Zempleni J, Mock DM. Advanced analysis of biotin metabolites in body fluids allows a more accurate measurement of biotin bioavailability and metabolism in humans. J Nutr. 1999 02; 129(2S Suppl):494S-497S. PMID: 10064316.
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Mock DM, Lankford GL, Widness JA, Burmeister LF, Kahn D, Strauss RG. Measurement of red cell survival using biotin-labeled red cells: validation against 51Cr-labeled red cells. Transfusion. 1999 Feb; 39(2):156-62. PMID: 10037125.
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Zempleni J, Mock DM. The efflux of biotin from human peripheral blood mononuclear cells. J Nutr Biochem. 1999 Feb; 10(2):105-9. PMID: 15539277.
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Mock DM. Biotin status: which are valid indicators and how do we know? J Nutr. 1999 02; 129(2S Suppl):498S-503S. PMID: 10064317.
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Mock DM, Lankford GL, Widness JA, Burmeister LF, Kahn D, Strauss RG. Measurement of circulating red cell volume using biotin-labeled red cells: validation against 51Cr-labeled red cells. Transfusion. 1999 Feb; 39(2):149-55. PMID: 10037124.
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Mock DM. Biotin physiology, dietary sources and requirements. 1999; 170-77.
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Mock NI, Evans TT, Mock DM. Biotin supplementation during pregnancy reverses depleted biotin status as assessed by excretion of urinary 3-hydroxyisovaleric acid (3HIA). FASEB Meeting. 1999; 13(5)A923.
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Mock NI, Evans TT, Mock DM. Biotin responsive urinary excretion of urinary 3-hydroxyisovaleric acid: evidence that marginal biotin status is common in normal pregnancy. NASPGN Meeting. 1999; 29(4):513.
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Mock DM. Biotin. 1999; 459-466.
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Mock DM, Zempleni J. Increased carboxylase synthesis: a potential cause of increased biotin uptake into proliferating peripheral blood mononuclear cells. NASPGN Meeting. 1999; 29(4):516.
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Mock DM. Nutrition, Biochemistry and Molecular Biology of Biotin. 1999; 129:2S:476S.
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Mock DM, Zempleni J. Chemical synthesis of biotinylated histones and analysis by sds-page/streptavidin-peroxidase. NASPGN Meeting. 1999; 29(4):517.
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Mock DM, Stewart CW, Mock NI, Hansen D. Maternal biotin deficiency (BD) causes fetal malformation (FM) by inducing fetal BD. NASPGN Meeting. 1999; 29(4):504.
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Stewart CW, Mock NI, Hansen D, Mock DM. Maternal biotin deficiency (BD) causes fetal malformation (FM) by inducing fetal BD. FASEB Meeting. 1999; 13(4):A229.
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Lu Y, Xuan M, Takata T, Wang C, He Z, Zhou Z, Mock D, Nikai H. Odontogenic tumors. A demographic study of 759 cases in a Chinese population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998 Dec; 86(6):707-14. PMID: 9868729.
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Zempleni J, Mock DM. Uptake and metabolism of biotin by human peripheral blood mononuclear cells. Am J Physiol. 1998 08; 275(2):C382-8. PMID: 9688592.
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Mock DM, Mock NI, Nelson RP, Lombard KA. Disturbances in biotin metabolism in children undergoing long-term anticonvulsant therapy. J Pediatr Gastroenterol Nutr. 1998 Mar; 26(3):245-50. PMID: 9523856.
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Wang K-S, Mock DM, Kearns GL. Pharmacokinetics (PK) of 14C-biotin administered intravenously to pigs in physiologic amounts. FASEB Meeting. 1998; 12:A247.
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LaBorde JB, Wall KS, Mock NI, Mock DM, Hansen DK. Embryotoxicity of dietary biotin deficiency. 1998; 57(4/5):233.
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Zempleni J, Mock DM. Biotin transport by human lymphocytes. SSPR Meeting. 1998; 46:A7.
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Mock NI, Evans T, Mock DM. Urinary 3-hydroxypropionic acid is not an early indicator of biotin deficiency. FASEB Meeting. 1998; 12:A247.
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Wang K-S, Mock DM, Kearns GL. Pharmacokinetics and tissue distribution of radiolabeled biotin administered intravenously to pigs at tracer and physiologic amount. SSPR Meeting. 1998; 46:A34.
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Zempleni J, Mock DM. The efflux of biotin from human lymphocytes. FASEB Meeting. 1998; 12:A247.
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Wolf B, Norrgard K, Pomponio RJ, Mock DM, McVoy JR, Fleischhauer K, Shapiro S, Blitzer MG, Hymes J. Profound biotinidase deficiency in two asymptomatic adults. Am J Med Genet. 1997 Nov 28; 73(1):5-9. PMID: 9375914.
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Mock DM, Dyken ME. Biotin catabolism is accelerated in adults receiving long-term therapy with anticonvulsants. Neurology. 1997 Nov; 49(5):1444-7. PMID: 9371938.
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Wang KS, Mock NI, Mock DM. Biotin biotransformation to bisnorbiotin is accelerated by several peroxisome proliferators and steroid hormones in rats. J Nutr. 1997 Nov; 127(11):2212-6. PMID: 9349849.
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Mock DM, Mock NI, Stratton SL. Concentrations of biotin metabolites in human milk. J Pediatr. 1997 Sep; 131(3):456-8. PMID: 9329428.
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Zempleni J, Trusty TA, Mock DM. Lipoic acid reduces the activities of biotin-dependent carboxylases in rat liver. J Nutr. 1997 Sep; 127(9):1776-81. PMID: 9278559.
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Zempleni J, Green GM, Spannagel AW, Mock DM. Biliary excretion of biotin and biotin metabolites is quantitatively minor in rats and pigs. J Nutr. 1997 Aug; 127(8):1496-500. PMID: 9237943.
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Mock DM, Lankford GL, Burmeister LF, Strauss RG. Circulating red cell volume and red cell survival can be accurately determined in sheep using the [14C]cyanate label. Pediatr Res. 1997 Jun; 41(6):916-21. PMID: 9167209.
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Mock DM, Stadler DD. Conflicting indicators of biotin status from a cross-sectional study of normal pregnancy. J Am Coll Nutr. 1997 Jun; 16(3):252-7. PMID: 9176832.
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Mock DM, Stadler DD, Stratton SL, Mock NI. Biotin status assessed longitudinally in pregnant women. J Nutr. 1997 May; 127(5):710-6. PMID: 9164991.
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Mock NI, Malik MI, Stumbo PJ, Bishop WP, Mock DM. Increased urinary excretion of 3-hydroxyisovaleric acid and decreased urinary excretion of biotin are sensitive early indicators of decreased biotin status in experimental biotin deficiency. Am J Clin Nutr. 1997 Apr; 65(4):951-8. PMID: 9094878.
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Mock DM, Mock NI. Serum concentrations of bisnorbiotin and biotin sulfoxide increase during both acute and chronic biotin supplementation. J Lab Clin Med. 1997 Mar; 129(3):384-8. PMID: 9042824.
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Mock DM, Strauss RG, Lankford GL. [14C]cyanate labeling of sheep red cells: covalent binding to hemoglobin continues in vivo for a day. Pediatr Res. 1997 Mar; 41(3):424-9. PMID: 9078546.
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Mock DM, Wang KS, Kearns GL. The pig is an appropriate model for human biotin catabolism as judged by the urinary metabolite profile of radioisotope-labeled biotin. J Nutr. 1997 Feb; 127(2):365-9. PMID: 9039841.
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Zempleni J, McCormick DB, Mock DM. Identification of biotin sulfone, bisnorbiotin methyl ketone, and tetranorbiotin-l-sulfoxide in human urine. Am J Clin Nutr. 1997 Feb; 65(2):508-11. PMID: 9022537.
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Mock DM, Heird GM. Urinary biotin analogs increase in humans during chronic supplementation: the analogs are biotin metabolites. Am J Physiol. 1997 Jan; 272(1 Pt 1):E83-5. PMID: 9038855.
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Mock DM. Determinations of biotin in biological fluids. Methods Enzymol. 1997; 279:265-75. PMID: 9211278.
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Wang K-S, Mock DM. Biotin biotransformation is increased by peroxisome proliferators (PP) in rats. FASEB Meeting. 1997; 11:A233.
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Zempleni J, Green GM, Spannagel AU, Mock DM. The biliary excretion of biotin metabolites is a quantitatively minor route of excretion in rats. FASEB Meeting. 1997; 11:A233.
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Wang KS, Patel A, Mock DM. The metabolite profile of radioisotope-labeled biotin in rats indicates that rat biotin metabolism is similar to that in humans. J Nutr. 1996 Jul; 126(7):1852-7. PMID: 8683347.
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Mock DM. Present Knowledge of Nutrition. Biotin. 1996; 22.
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Stratton S, Mock NI, Mock DM. Biotin and biotin metabolites in human milk: The metabolites are not negligible. SSPR Meeting. 1996; 44:58A.
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Mock DM, Mock NI, Stratton SL, Heird GM, Stadler DD. Increased excretion of 3-hydroxyisovaleric acid provides evidence of biotin deficiency during pregnancy. FASEB Meeting. 1996; 10:A465.
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Mock DM, Mock NI. : In human subjects, urinary excretion of biotin (BIO) analogs increases during chronic biotin supplementation, providing evidence that these analogs are biotin metabolites. DDW Meeting. 1996; 110:A822.
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Wang KS, Kearns GL, Mock DM. Urinary metabolic profile of radioisotope labeled biotin administered intravenously to the pig: The pig is an appropriate model for human biotin catabolism. SSPR Meeting. 1996; 44:58A.
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Zempleni J, Mock DM, Stratton SL, McCormick DB. Lipoic acid analogs and L-tryptophan do not interfere with the assay of biotin by HPLC/avidin-binding assay. FASEB Meeting. 1996; 10:A802.
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Cordle DG, Strauss RG, Lankford G, Mock DM. Antibodies provoked by transfusion of biotin-labeled red blood cells. American Assoc of Blood Banks Meeting. 1996; 36:46S.
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Mock DM, Lankford GL, Strauss RG, Kahn D, Widness JA. Circulating red cell volume (RCV): Validation of a nonradioactive method in adult volunteers. SSPR Meeting. 1996; 44:76A.
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Mock DM, Lankford GL, Strauss RG, Kahn D, Widness JA. of a nonradioactive method for determination of red cell survival (RCS) in adult volunteers. SSPR Meeting. 1996; 44:76A.
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Mock DM, Stratton, SL, Mock NI. Biotin and biotin metabolites in human milk: The metabolites are not negligible. FASEB Meeting. 1996; 10:A802.
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Mock DM, Lankford GL, Mock NI. Biotin accounts for only half of the total avidin-binding substances in human serum. J Nutr. 1995 Apr; 125(4):941-6. PMID: 7722698.
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Mock NI, Mock DM, Malik M, Stumbo P, Bishop W. Urinary biotin excretion as an early indicator of biotin deficiency. SSPR Meeting. 1995; 43:55A.
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Mock NI, Mock DM, Malik M, Stumbo P, Bishop W. Urinary excretion of biotin and 3-hydroxyisovaleric acid (3-HIA) are early indicators of biotin deficiency. FASEB Meeting. 1995; 9:part II A985.
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Mock DM, Wang KS, Kearns GL. Urinary Metabolic Profile of Radioisotope Labeled Biotin in the Pig. NASPGN Meeting. 1995; 21:358.
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Mock DM, Stratton S, Stadler D, Mock NI. Urinary excretion of biotin increases during pregnancy providing evidence of decreased biotin status. SSPR Meeting. 1995; 43:55A.
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Wang K-S, Patel A, Mock DM. Excretion rates and metabolic profile of radioisotope labeled biotin in the rat. SSPR Meeting. 1995; 43:55A.
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Wang K-S, Patel A, Mock DM. Excretion rates and metabolic profile of radioisotope labeled biotin in the rat. FASEB Meeting. 1995; 9:part I A155.
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Mock DM, Lankford GL, Strauss R. Circulating red cell volume (RCV): Validation of a nonradioactive method in sheep. SPR Meeting. 1995; 37:part 2 284A.
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Mock DM, Stratton S, Stadler D, Mock NI. Urinary excretion of biotin decreases during pregnancy providing evidence of decreased biotin status. FASEB Meeting. 1995; 9:part I A155.
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Mock DM, Lankford GL, Strauss R. Validation of a nonradioactive method for determination of red cell survival (RCS) in sheep. SPR Meeting. 1995; 37:part 2 284A.
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Mock DM, Dyken M. Biotin deficiency results from long-term therapy with anticonvulsants. AGA Meeting. 1995; 108:A740.
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Lankford GL, Mock DM, Strauss R. Both survival of red blood cells (RBC) and circulating red cell volume (RCV) can be accurately determined in sheep using 14C -cyanate labeled RBC. FASEB Meeting. 1995; 9:part II A904.
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Nenov VI, Read W, Mock D. Computer applications in the intensive care unit. Neurosurg Clin N Am. 1994 Oct; 5(4):811-27. PMID: 7827486.
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Hu ZQ, Henderson GI, Mock DM, Schenker S. Biotin uptake by basolateral membrane vesicles of human placenta: normal characteristics and role of ethanol. Proc Soc Exp Biol Med. 1994 Sep; 206(4):404-8. PMID: 7521055.
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Fields M, Lewis CG, Lure MD, Mock NI, Mock DM. Requirements for biotin are not affected by the combination of copper deficiency and fructose feeding. J Am Coll Nutr. 1994 Apr; 13(2):174-8. PMID: 8006299.
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Hapak L, Gordon A, Locker D, Shandling M, Mock D, Tenenbaum HC. Differentiation between musculoligamentous, dentoalveolar, and neurologically based craniofacial pain with a diagnostic questionnaire. J Orofac Pain. 1994; 8(4):357-68. PMID: 7670423.
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Mock DM, Mock NI. Serum concentrations of biotin and biotin analogs increase during acute and chronic biotin supplementation. FASEB Meeting. 1994; 8:A921 #5335.
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Mock NI, Mock DM. Biotin represents about half of total identified avidin-binding substances in human serum. FASEB Meeting. 1994; 8:A447 #2587.
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Mock DM, Strauss R. Survival of red blood cells (RBC) in circulation can be accurately determined in sheep using 14C-cyanate labeled RBC. SPR Meeting. 1994; 35(4)part2 #980.
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Mock DM, Strasuss R. Time course of 14C-cyanate labeling in sheep RBC: Covalent binding to RBC probably continues for 1 day in vivo. SPR Meeting. 1994; 35:981.
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Mock DM, Strauss R. Circulating red cell volume (RCV) of sheep can be accurately determined using 14C-cyanate labeled red blood cells (RBC). SPR Meeting. 1994; 35:982.
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Jundt JW, Browne BA, Fiocco GP, Steele AD, Mock D. A comparison of low dose methotrexate bioavailability: oral solution, oral tablet, subcutaneous and intramuscular dosing. J Rheumatol. 1993 Nov; 20(11):1845-9. PMID: 8308768.
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Mock DM, Lankford GL, Cazin J. Biotin and biotin analogs in human urine: biotin accounts for only half of the total. J Nutr. 1993 Nov; 123(11):1844-51. PMID: 8229299.
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Schenker S, Hu ZQ, Johnson RF, Yang Y, Frosto T, Elliott BD, Henderson GI, Mock DM. Human placental biotin transport: normal characteristics and effect of ethanol. Alcohol Clin Exp Res. 1993 Jun; 17(3):566-75. PMID: 8333586.
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Mock DM. Biotin. 1993; 399-405.
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Mock DM, Malik MI. Distribution of biotin in human plasma: most of the biotin is not bound to protein. Am J Clin Nutr. 1992 Aug; 56(2):427-32. PMID: 1636621.
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Mock NI, Mock DM. Biotin deficiency in rats: disturbances of leucine metabolism are detectable early. J Nutr. 1992 Jul; 122(7):1493-9. PMID: 1619476.
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Mock DM, Mock NI, Langbehn SE. Biotin in human milk: methods, location, and chemical form. J Nutr. 1992 Mar; 122(3):535-45. PMID: 1542011.
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Mock DM, Mock NI, Dankle JA. Secretory patterns of biotin in human milk. J Nutr. 1992 Mar; 122(3):546-52. PMID: 1542012.
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Mock DM. Rayon balls and disposable-diaper material selectively adsorb creatinine. Am J Clin Nutr. 1992 Feb; 55(2):326-30. PMID: 1734668.
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Schenker S, Johnson R, Henderson G, Yang Y, Elliott B, Mock DM. Biotin transport by the human placenta: Normal characteristics & role of ethanol. FASEB Meeting. 1992; 6:A1942 #5824.
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Mock DM. Skin manifestations of biotin deficiency. Semin Dermatol. 1991 Dec; 10(4):296-302. PMID: 1764357.
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Mock DM. Mechanisms Regulating Lactation and Infant Nutrient Utilization. Biotin in Human Milk. 1991; 211-22.
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Said HM, Sharifian A, Bagherzadeh A, Mock D. Chronic ethanol feeding and acute ethanol exposure in vitro: effect on intestinal transport of biotin. Am J Clin Nutr. 1990 Dec; 52(6):1083-6. PMID: 2239786.
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Mock DM, Lankford G. Studies of the reversible binding of biotin to human plasma. J Nutr. 1990 Apr; 120(4):375-81. PMID: 2329390.
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Mock DM. Evidence for a pathogenic role of omega 6 polyunsaturated fatty acid in the cutaneous manifestations of biotin deficiency. J Pediatr Gastroenterol Nutr. 1990 Feb; 10(2):222-9. PMID: 2303973.
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Mock DM, Horowitz P. Fluorometric assay for avidin-biotin interaction. Methods Enzymol. 1990; 184:234-40. PMID: 2388573.
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Mock DM. Sequential solid-phase assay for biotin based on 125I-labeled avidin. Methods Enzymol. 1990; 184:224-33. PMID: 2201876.
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Said HM, Horne DW, Mock DM. Effect of aging on intestinal biotin transport in the rat. Exp Gerontol. 1990; 25(1):67-73. PMID: 2318284.
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Sharifian A, Said HM, Bagherzadeh A, Mock DM. Effect of chronic ethanol feeding and acute ethanol exposure in vitro on intestinal transport of biotin. FASEB Meeting. 1990; 4:A364.
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Mock DM. Present Knowledge in Nutrition. Biotin. 1990; 21.
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Mock DM. Rayon and diaper material selectively adsorb urinary creatinine. Midwest AFCR/SPR Meeting. 1990; 38:832A.
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Mock NI, Dankle J, Mock DM. Validation of sampling techniques for the measurement of free biotin in human milk. FASEB Meeting. 1990; 4:A788 #3025.
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Mock DM, Lankford GL. A substantial percentage of the avidin-binding substances (ABS) in human urine is not biotin. FASEB Meeting. 1990; 4:A510 #1363.
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Lombard KA, Mock DM, Nelson RP. Does long-term anticonvulsant therapy predictably cause biotin deficiency in children?. ASCNM Meeting. 1990; 51:518.
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Yee SP, Mock D, Greer P, Maltby V, Rossant J, Bernstein A, Pawson T. Lymphoid and mesenchymal tumors in transgenic mice expressing the v-fps protein-tyrosine kinase. Mol Cell Biol. 1989 Dec; 9(12):5491-9. PMID: 2555699.
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Tolaymat N, Mock DM. Biotin analysis of commercial vitamin and other nutritional supplements. J Nutr. 1989 Oct; 119(10):1357-60. PMID: 2585128.
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Mock DM, Jackson H, Lankford GL, Mock NI, Weintraub ST. Quantification of urinary 3-hydroxyisovaleric acid using deuterated 3-hydroxyisovaleric acid as internal standard. Biomed Environ Mass Spectrom. 1989 Sep; 18(9):652-6. PMID: 2790256.
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Lombard KA, Mock DM. Biotin nutritional status of vegans, lactoovovegetarians, and nonvegetarians. Am J Clin Nutr. 1989 Sep; 50(3):486-90. PMID: 2773827.
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Lavigueur A, Maltby V, Mock D, Rossant J, Pawson T, Bernstein A. High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene. Mol Cell Biol. 1989 Sep; 9(9):3982-91. PMID: 2476668.
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Yee SP, Mock D, Maltby V, Silver M, Rossant J, Bernstein A, Pawson T. Cardiac and neurological abnormalities in v-fps transgenic mice. Proc Natl Acad Sci U S A. 1989 Aug; 86(15):5873-7. PMID: 2788278.
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Brown BP, Sato Y, Mock D, Mitros F, Franken EA. Pneumococcal colitis: report of a case with radiologic and endoscopic findings. J Pediatr Gastroenterol Nutr. 1989 Feb; 8(2):269-71. PMID: 2709257.
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Said HM, Mock DM, Collins JC. Regulation of intestinal biotin transport in the rat: effect of biotin deficiency and supplementation. Am J Physiol. 1989 Feb; 256(2 Pt 1):G306-11. PMID: 2919673.
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Said HM, Horne D, Mock DM. Influence of aging on intestinal biotin transport in the rat. DDW Meeting. 1989; 96:5:A435.
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Mock DM. Biotin deficiency due to total parenteral nutrition alters serum fatty acid composition. Nutrit Rev. 1989; 47(4).
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Mock NI, Lankford GL, Mock DM. Application of an improved method for determination of urinary 3-hydroxyisovaleric acid (3-OH ISOVAL). FASEB Meeting. 1989; 3:A667.
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Lankford GL, Mock DM. Conversion of biotin sulfoxide to biotin: An explanation for part of the increase in the plasma concentration of biotin during acid hydrolysis. FASEB Meeting. 1989; 3:A666.
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Mock NI, Mock DM. Use of an improved method for determination of urinary 3-hydroxyisovaleric acid allows earlier detection of biotin deficiency in the rat. Midwest AFCR/SPR Meeting. 1989; 37:955A.
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Mock DM, Lankford GL. The concentration of biotin sulfoxide in human plasma is not negligible compared to biotin. FASEB Meeting. 1989; 3:A1058.
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Mock DM. Biotin analogs account for half of the total avidin-binding substances in human plasma. Midwest AFCR/SPR Meeting. 1989; 37:955A.
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Suter M, Cazin J, Butler JE, Mock DM. Isolation and characterization of highly purified streptavidin obtained in a two-step purification procedure from Streptomyces avidinii grown in a synthetic medium. J Immunol Methods. 1988 Oct 04; 113(1):83-91. PMID: 3049826.
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Mock DM, Mock NI, Johnson SB, Holman RT. Effects of biotin deficiency on plasma and tissue fatty acid composition: evidence for abnormalities in rats. Pediatr Res. 1988 Sep; 24(3):396-403. PMID: 3211626.
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Mock DM, Lankford G, Horowitz P. A study of the interaction of avidin with 2-anilinonaphthalene-6-sulfonic acid as a probe of the biotin binding site. Biochim Biophys Acta. 1988 Aug 31; 956(1):23-9. PMID: 3408737.
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Mock DM, Mock NI, Weintraub S. Abnormal organic aciduria in biotin deficiency: the rat is similar to the human. J Lab Clin Med. 1988 Aug; 112(2):240-7. PMID: 3397627.
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Spector R, Mock DM. Biotin transport and metabolism in the central nervous system. Neurochem Res. 1988 Mar; 13(3):213-9. PMID: 3386776.
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Mock DM, Johnson SB, Holman RT. Effects of biotin deficiency on serum fatty acid composition: evidence for abnormalities in humans. J Nutr. 1988 Mar; 118(3):342-8. PMID: 2895169.
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Mock DM, Lankford GL. The percent of biotin reversibly bound to plasma protein is small. Midwest AFCR/SPR Meeting. 1988; 36:895A.
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Mock DM, Lankford GL, Horowitz P. A study of the interaction of avidin with 2-anilinonaphthalene-6-sulfonic acid (2,6 ANS) as a probe of the biotin binding site. Midwest AFCR/SPR Meeting. 1988; 36:895A.
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Lombard KA, Mock DM. Biotin nutritional status of strict vegetarians. Midwest AFCR/SPR Meeting. 1988; 36:895A.
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Langbehn SE, Mock DM. Biotin concentration in human milk subcompartments. Midwest AFCR/SPR Meeting. 1988; 36:894A.
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Mock DM. Evidence for a pathogenetic role of w6 fatty acid (PUFA) abnormalities in the cutaneous manifestations of biotin deficiency. Midwest AFCR/SPR Meeting. 1988; 36:895A.
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Lankford GL, Mock DM. The percent of biotin reversibly bound to plasma protein is small. FASEB Meeting. 1988; 2:A440.
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Mock DM. Evidence for a pathogenic role of fatty acid (FA) abnormalities in the cutaneous manifestations of biotin deficiency. FASEB Meeting. 1988; 2:A1204.
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Mock D, Whitestone B, Freeman J. Gamma-glutamyl transpeptidase activity in human oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol. 1987 Aug; 64(2):197-201. PMID: 2442690.
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Mock DM. Water-soluble vitamin requirements of the preterm infant. J Pediatr Gastroenterol Nutr. 1987 May-Jun; 6(3):323-5. PMID: 3430240.
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Spector R, Mock D. Biotin transport through the blood-brain barrier. J Neurochem. 1987 Feb; 48(2):400-4. PMID: 3098919.
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Mock NI, Mock DM, Holman R, Johnson S. Effects of biotin deficiency on fatty acid composition of human and the rat. FASEB Meeting. 1987; 46:1489.
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Mock DM. A substantial percentage of the avidin-binding substances in human plasma is not biotin. FASEB Mini-symposium. 1987; 46:1159.
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Mock DM, Grendell JH, Cello J, Morris RC. Pancreatitis and alcoholism disorder the renal tubule and impair reclamation of some low molecular weight proteins. Gastroenterology. 1987; 92(1):161 - 170.
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Mock DM, Mock NI, Weintraub S. Abnormal organic aciduria in biotin deficiency: Rat is similar to man. Midwest AFCR/SPR Meeting. 1987; 35:907A.
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Al-Bander HA, Mock DM, Etheredge SB, Paukert TT, Humphreys MH, Morris RC. Coordinately increased lysozymuria and lysosomal enzymuria induced by maleic acid. Kidney Int. 1986; 30(6):804 - 812.
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Mock DM. Fatty acids and Reye's syndrome. Hepatology. 1986; 6(6):1414 - 1415.
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Mock DM. Growth retardation in chronic inflammatory bowel disease. Gastroenterology. 1986; 91(4):1019 - 1021.
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Mock DM, DuBois DB. A sequential, solid-phase assay for biotin in physiologic fluids that correlates with expected biotin status. Anal Biochem. 1986 Mar; 153(2):272-8. PMID: 3706711.
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Mock DM, Spector R. Biotin transport through the blood-brain barrier of the rat. Midwest Society for Pediatrics Research\Plenary Session. 1986; 34:977A.
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Mock DM. Water-soluble vitamin supplementation and the importance of biotin. 1986; 108.
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Larsen PD, Mock DM, O'Connor PS. Vitamin E deficiency associated with vision loss and bulbar weakness. Ann Neurol. 1985; 18(6):725 - 727.
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Mock DM, Langford G, Dubois D, Criscimagna N, Horowitz P. A fluorometric assay for the biotin-avidin interaction based on displacement of the fluorescent probe 2-anilinonaphthalene-6-sulfonic acid. Anal Biochem. 1985 Nov 15; 151(1):178-81. PMID: 4091277.
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Mock DM, Baswell DL, Baker H, Holman RT, Sweetman L. Biotin deficiency complicating parenteral alimentation: diagnosis, metabolic repercussions, and treatment. J Pediatr. 1985 May; 106(5):762-9. PMID: 3923177.
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Mock DM, Baswell DL, Baker H, Holman RT, Sweetman L. Biotin deficiency complicating parenteral alimentation: diagnosis, metabolic repercussions, and treatment. Ann N Y Acad Sci. 1985; 447:314-34. PMID: 3925860.
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Mock DM. Biotin Deficiency. Biomed & Pharmacother. 1985; 39:248.
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Mock DM, Baswell DL, Baker, H, Holman R, Sweetman L. Biotin deficiency complicating parenteral alimentation. American Gastroenterological Association Meeting. 1984; 86:1185.
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Mock DM, Scott M, Mock NI, Thaler MM. The proportion of mitochondrial isoenzyme of aspartate aminotransferase is not elevated in Reye's syndrome. Pediatr Res. 1983 Nov; 17(11):884-8. PMID: 6646898.
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Mock DM, Perman JA, Thaler M, Morris RC. Chronic fructose intoxication after infancy in children with hereditary fructose intolerance. A cause of growth retardation. N Engl J Med. 1983; 309(13):764 - 770.
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Mock DM. Biotin deficiency complicating parenteral alimentation. JAMA. 1983 Aug 26; 250(8):1028. PMID: 6410087.
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Mock DM. Biotin deficiency complicating parenteral alimentation. JAMA. 1983; 250(8):1028 - .
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Mock DM. Biotin deficiency complicating parenteral alimentation. J Am Med Assoc. 1983; (250):1028.
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Hintz MJ, Mock DM, Peterson LL, Tuttle K, Peterson JA. Equilibrium and kinetic studies of the interaction of cytochrome P-450cam and putidaredoxin. J Biol Chem. 1982; 257(23):14324 - 14332.
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Mock DM, Bruno GV, Griffin BW, Peterson JA. Low temperature EPR spectroscopic characterization of the interaction of cytochrome P-450cam with a spin label analog of metyrapone. J Biol Chem. 1982; 257(10):5372 - 5379.
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Mock DM, Grendell JH, Cello JP, Morris RC Jr. Chronic alcohol ingestion injures the renal tubule. 1982; 21:254A.
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Mock DM, Grendell JH, Cello JP, Morris RC Jr. The amylase creatinine clearance ratio (Camy/Ccr) in pancreatitis depends upon etiology. Western AFCR Meeting. 1982; 30:37A.
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Mock DM, deLorimer AA, Liebman WM, Sweetman L, Baker H. Biotin deficiency: an unusual complication of parenteral alimentation. N Engl J Med. 1981 Apr 02; 304(14):820-3. PMID: 6782478.
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Mock DM, Liebman W, Delorimer A. Biotin deficiency: A novel complication of parenteral alimentation. Western AFCR Meeting. 1981; 29:136A.
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Mock DM, Liebman W, DeLorimer A, Sweetman L, Baker H. Biotin deficiency: A novel complication of parenteral alimentation. 1981; 15:541.
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Mock DM, Perman JA, Thaler MM, Morris RC. Biotin deficiency: A novel complication of parenteral alimentation. 1981; 29:58A.
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Mock DM, Perman JA, Tsai H, Thaler MM, Morris RC Jr. Chronic fructose intoxication in apparently asymptomatic patients with hereditary fructose intolerance. 1981; 29:416A.
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Mock DM. More on biotin deficiency, parenteral alimentation and lactic acidosis. 1981; 1116.
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Al-Bander HA, Mock DM, Paukert T, Humphreys MH, Morris RC Jr. Biotin deficiency: A novel complication of parenteral alimentation. Natl ASCI Meeting. 1981; 29:552A.
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Mock DM, Perman JA, Rosenthal P, Harrison MR, Thaler MM. Cholelithiasis in a 2-year-old child with reflux esophagitis and hiatus hernia. J Pediatr. 1980 May; 96(5):878-9. PMID: 7365594.
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Berger JL, Mock D. Evaluation of a hospital dental emergency service. J Hosp Dent Pract. 1980; 14(3):100-4. PMID: 6964974.
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Mock DM, Perman J, Et al. Reversible growth retardation in the older child: A previously unrecognized complication of hereditary fructose intolerance. 1980; 14:913.
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Peterson JA, Mock DM. Cytochrome P-450cam and putidaredoxin interaction during electron transfer. Acta Biol Med Ger. 1979; 38(2-3):153 - 162.
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Mock DM. Characterization of the interaction of cytochrome P-450 and Pseudomonas putida with a spin-labeled inhibitor and with putidaredoxin. Dissertation. 1978.
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Peterson JA, Mock DM. Dual wavelength/stopped flow spectrophotometry: computer acquisition and analysis. Anal Biochem. 1975 Oct; 68(2):545-53. PMID: 1200354.
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Peterson JA, Mock DM. Metabolic control of cytochrome P-450 cam. Adv Exp Med Biol. 1975; 58(00):311 - 324.
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Moretti H, Matthews N, Mock DM. Does excess biotin supplementation normalize propionly-CoA carboxylase activity in peripheral blood lymphocytes of subjects receiving long-term dialysis?.
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Mock DM. Contributor.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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Year | Publications |
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1988 | 13 | 1989 | 15 | 1990 | 12 | 1991 | 2 | 1992 | 6 | 1993 | 4 | 1994 | 9 | 1995 | 12 | 1996 | 11 | 1997 | 18 | 1998 | 9 | 1999 | 21 | 2000 | 13 | 2001 | 14 | 2002 | 9 | 2003 | 5 | 2004 | 13 | 2005 | 10 | 2006 | 1 | 2007 | 4 | 2008 | 13 | 2009 | 8 | 2010 | 8 | 2011 | 15 | 2012 | 4 | 2013 | 4 | 2014 | 3 | 2015 | 4 | 2016 | 5 | 2017 | 6 | 2018 | 2 | 2019 | 1 | 2022 | 1 |
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