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Grazyna Nowak

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentCollege of Pharmacy, College of Provost
DivisionPharmaceutical Science
AddressB238B Biomedical Research I
325 S. Elm St.
Mail Slot # 522-3
Little Rock AR 72205
Phone501-686-6345
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    Collapse Research Funds 
    Collapse research activities
    15-B-27     (NOWAK, GRAZYNA)Nov 21, 2014 - Jun 30, 2016
    Arkansas Science & Technology Authority
    Gamma-Tocotrienol Administration as a Novel Approach to Reduce Acute Kidney Injury
    Role: Principal Investigator

    0151416Z     (NOWAK, GRAZYNA)Jul 1, 2001 - Jun 30, 2004
    American Heart Association (Midwest Affiliate)
    Protein Kinase C and Regulation of Mitochondrial Function During Hypoxia
    Role: Principal Investigator

    R01DK059558     (NOWAK, GRAZYNA)Apr 1, 2001 - Mar 31, 2006
    NIH/NIDDK
    Protein Kinase C in the Repair of Cellular Functions
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Nowak G, Megyesi J, Craigen WJ. Deletion of VDAC1 Hinders Recovery of Mitochondrial and Renal Functions After Acute Kidney Injury. Biomolecules. 2020 Apr 10; 10(4). PMID: 32290153.
      View in: PubMed
    2. Nowak G, Megyesi J. Protein kinase Ca mediates recovery of renal and mitochondrial functions following acute injury. FEBS J. 2020 May; 287(9):1830-1849. PMID: 31659858.
      View in: PubMed
    3. Nowak G, Bakajsova-Takacsova D. Protein kinase Ce targets respiratory chain and mitochondrial membrane potential but not F0 F1 -ATPase in renal cells injured by oxidant. J Cell Biochem. 2018 11; 119(11):9394-9407. PMID: 30074270.
      View in: PubMed
    4. Nowak G, Takacsova-Bakajsova D, Megyesi J. Deletion of protein kinase C-e attenuates mitochondrial dysfunction and ameliorates ischemic renal injury. Am J Physiol Renal Physiol. 2017 01 01; 312(1):F109-F120. PMID: 27760765.
      View in: PubMed
    5. Nowak G, Bakajsova D. Protein kinase C-a interaction with F0F1-ATPase promotes F0F1-ATPase activity and reduces energy deficits in injured renal cells. J Biol Chem. 2015 Mar 13; 290(11):7054-66. PMID: 25627689.
      View in: PubMed
    6. Sridharan V, Aykin-Burns N, Tripathi P, Krager KJ, Sharma SK, Moros EG, Corry PM, Nowak G, Hauer-Jensen M, Boerma M. Radiation-induced alterations in mitochondria of the rat heart. Radiat Res. 2014 Mar; 181(3):324-34. PMID: 24568130.
      View in: PubMed
    7. Nowak G, Soundararajan S, Mestril R. Protein kinase C-a interaction with iHSP70 in mitochondria promotes recovery of mitochondrial function after injury in renal proximal tubular cells. Am J Physiol Renal Physiol. 2013 Sep 01; 305(5):F764-76. PMID: 23804450.
      View in: PubMed
    8. Nowak G, Bakajsova D. Assessment of mitochondrial functions and cell viability in renal cells overexpressing protein kinase C isozymes. J Vis Exp. 2013 Jan 07; (71). PMID: 23328793.
      View in: PubMed
    9. Nowak G, Bakajsova D. Protein kinase C-a activation promotes recovery of mitochondrial function and cell survival following oxidant injury in renal cells. Am J Physiol Renal Physiol. 2012 Aug 15; 303(4):F515-26. PMID: 22674023.
      View in: PubMed
    10. Nowak G, Bakajsova D, Hayes C, Hauer-Jensen M, Compadre CM. ?-Tocotrienol protects against mitochondrial dysfunction and renal cell death. J Pharmacol Exp Ther. 2012 Feb; 340(2):330-8. PMID: 22040679.
      View in: PubMed
    11. Nowak G, Bakajsova D, Samarel AM. Protein kinase C-epsilon activation induces mitochondrial dysfunction and fragmentation in renal proximal tubules. Am J Physiol Renal Physiol. 2011 Jul; 301(1):F197-208. PMID: 21289057.
      View in: PubMed
    12. Shaik ZP, Fifer EK, Nowak G. Akt activation improves oxidative phosphorylation in renal proximal tubular cells following nephrotoxicant injury. Am J Physiol Renal Physiol. 2008 Feb; 294(2):F423-32. PMID: 18077599.
      View in: PubMed
    13. Nowak G, Clifton GL, Bakajsova D. Succinate ameliorates energy deficits and prevents dysfunction of complex I in injured renal proximal tubular cells. J Pharmacol Exp Ther. 2008 Mar; 324(3):1155-62. PMID: 18055880.
      View in: PubMed
    14. Shaik ZP, Fifer EK, Nowak G. Protein kinase B/Akt modulates nephrotoxicant-induced necrosis in renal cells. Am J Physiol Renal Physiol. 2007 Jan; 292(1):F292-303. PMID: 16940564.
      View in: PubMed
    15. Price PM, Yu F, Kaldis P, Aleem E, Nowak G, Safirstein RL, Megyesi J. Dependence of cisplatin-induced cell death in vitro and in vivo on cyclin-dependent kinase 2. J Am Soc Nephrol. 2006 Sep; 17(9):2434-42. PMID: 16914540.
      View in: PubMed
    16. Nowak G, Clifton GL, Godwin ML, Bakajsova D. Activation of ERK1/2 pathway mediates oxidant-induced decreases in mitochondrial function in renal cells. Am J Physiol Renal Physiol. 2006 Oct; 291(4):F840-55. PMID: 16705147.
      View in: PubMed
    17. Liu X, Godwin ML, Nowak G. Protein kinase C-alpha inhibits the repair of oxidative phosphorylation after S-(1,2-dichlorovinyl)-L-cysteine injury in renal cells. Am J Physiol Renal Physiol. 2004 Jul; 287(1):F64-73. PMID: 14996667.
      View in: PubMed
    18. Nowak G, Grant DF, Moran JH. Linoleic acid epoxide promotes the maintenance of mitochondrial function and active Na+ transport following hypoxia. Toxicol Lett. 2004 Mar 01; 147(2):161-75. PMID: 14757320.
      View in: PubMed
    19. Nowak G, Bakajsova D, Clifton GL. Protein kinase C-epsilon modulates mitochondrial function and active Na+ transport after oxidant injury in renal cells. Am J Physiol Renal Physiol. 2004 Feb; 286(2):F307-16. PMID: 14570699.
      View in: PubMed
    20. Nowak G, Price PM, Schnellmann RG. Lack of a functional p21WAF1/CIP1 gene accelerates caspase-independent apoptosis induced by cisplatin in renal cells. Am J Physiol Renal Physiol. 2003 Sep; 285(3):F440-50. PMID: 12746256.
      View in: PubMed
    21. Nowak G. Protein kinase C mediates repair of mitochondrial and transport functions after toxicant-induced injury in renal cells. J Pharmacol Exp Ther. 2003 Jul; 306(1):157-65. PMID: 12665543.
      View in: PubMed
    22. Nowak G. Protein kinase C-alpha and ERK1/2 mediate mitochondrial dysfunction, decreases in active Na+ transport, and cisplatin-induced apoptosis in renal cells. J Biol Chem. 2002 Nov 08; 277(45):43377-88. PMID: 12218054.
      View in: PubMed
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