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Galen Wenger

TitleProfessor Emeritus
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPharmacology & Toxicology, College of Medicine
DivisionPharmacology Cognitive Function
Address306E Biomedical Research I
4301 W Markham St.
Mail Slot # 611
Little Rock AR 72205
Phone501-686-8040
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    Collapse Research Funds 
    Collapse research activities
    SRA SN HT-NPS-1026     (WENGER, GALEN)Jul 16, 2007 - Jun 30, 2012
    Helicon Therapeutics, Inc.
    A behavioral screen of working memory efficacy for Helicon Therapeutics, Inc.
    Role: Principal Investigator
    R01HD047656     (WENGER, GALEN R)May 15, 2005 - Mar 31, 2011
    NIH/NICHD
    Age and Cognition in a Mouse Model of Down Syndrome
    Role: Principal Investigator
    R21DA014196     (WENGER, GALEN R)Apr 1, 2002 - Mar 31, 2006
    NIH/NIDA
    Strain Differences in Response to Opioids
    Role: Principal Investigator
    R03AA012271     (WENGER, GALEN R)Aug 1, 1999 - Jul 31, 2002
    NIH/NIAAA
    ETHANOL AND AMNESIC DRUGS IN P AND NP RATS
    Role: Principal Investigator
    R01AA011515     (WENGER, GALEN R)Mar 1, 1999 - Feb 28, 2002
    NIH/NIAAA
    ETHANOL EFFECTS ON VIGILANCE
    Role: Principal Investigator
    R01AA014977     (WENGER, GALEN R)Sep 25, 1997 - Dec 31, 2010
    NIH/NIAAA
    Alcohol Preference and Cognitive Function
    Role: Principal Investigator
    P01AG012411     (GRIFFIN, SUE TILTON)Jun 1, 1995 - May 31, 2021
    NIH/NIA
    Early Events in Alzheimer Pathogenesis
    Role: Co-Investigator
    R01DA007864     (WENGER, GALEN R)Mar 9, 1992 - Feb 29, 1996
    NIH/NIDA
    DRUGS OF ABUSE AND MEMORY FUNCTION--SITES OF ACTION
    Role: Principal Investigator
    R01DA005815     (WENGER, GALEN R)Sep 30, 1989 - Apr 30, 1999
    NIH/NIDA
    DRUGS OF ABUSE AND COGNITIVE BEHAVIOR
    Role: Principal Investigator
    R01DA004079     (WENGER, GALEN R)May 1, 1986 - Nov 30, 1989
    NIH/NIDA
    BEHAVIORAL AND CARDIOVASCULAR EFFECTS OF COCAINE ABUSE
    Role: Principal Investigator
    R01DA003393     (WENGER, GALEN R)Jun 1, 1983 - May 31, 1987
    NIH/NIDA
    STEREOSELECTIVE ASPECTS OF BARBITURATE ABUSE POTENTIAL
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Whitney KN, Wenger GR. Impulsivity and motor activity in aged, male Ts65Dn mice. Exp Clin Psychopharmacol. 2013 Oct; 21(5):345-54. PMID: 24099355.
      View in: PubMed
    2. Fowler TW, McKelvey KD, Akel NS, Vander Schilden J, Bacon AW, Bracey JW, Sowder T, Skinner RA, Swain FL, Hogue WR, Leblanc DB, Gaddy D, Wenger GR, Suva LJ. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment. PLoS One. 2012; 7(8):e42967. PMID: 22916188.
      View in: PubMed
    3. Whitney KN, Wenger GR. Working memory in the aged Ts65Dn mouse, a model for Down syndrome. Behav Brain Res. 2012 Jun 15; 232(1):202-9. PMID: 22503781.
      View in: PubMed
    4. Comer SD, Bickel WK, Yi R, de Wit H, Higgins ST, Wenger GR, Johanson CE, Kreek MJ. Human behavioral pharmacology, past, present, and future: symposium presented at the 50th annual meeting of the Behavioral Pharmacology Society. Behav Pharmacol. 2010 Jul; 21(4):251-77. PMID: 20664330.
      View in: PubMed
    5. Wenger GR, Hall CJ. Rats selectively bred for ethanol preference or nonpreference have altered working memory. J Pharmacol Exp Ther. 2010 May; 333(2):430-6. PMID: 20176684.
      View in: PubMed
    6. Wenger GR. Encyclopedia of Psychopharmacology. Rate-Dependency Theory. 2010; 1120-1124.
    7. Comer SD, Bickel WK, Yi R, De Wit H, Higgins ST, Wenger GR. Human Behavioral Pharmacology. Behavioral Pharmacology. 2010.
    8. Sanders NC, Williams DK, Wenger GR. Does the learning deficit observed under an incremental repeated acquisition schedule of reinforcement in Ts65Dn mice, a model for Down syndrome, change as they age? Behav Brain Res. 2009 Oct 12; 203(1):137-42. PMID: 19409933.
      View in: PubMed
    9. Sanders NC, Wenger GR. The learning deficit of the Ts65Dn mouse, a model for Down syndrome, persists with age but does not increase. FASEB J. 2009.
    10. Wenger GR. Alcohol preference in rats does not predict learning deficits or effect of alcohol on learning. Behav Pharmacology. 2009; S94, 20 (Suppl. 1).
    11. Whitney K, Wenger GR. An age-related deficit in working memory emerges in the Ts65Dn mouse, a murine model of Down syndrome. FASEB J. 2009.
    12. Whitney K, Wenger GR. Neither donepezil nor d-amphetamine improve working memory in the Ts65Dn mouse, a murine model of Down syndrome. FASEB J. 2008.
    13. Scott-McKean JJ, Wenger GR, Tecott LH, Costa AC. 5-HT(1A) Receptor Null Mutant Mice Responding Under a Differential-Reinforcement-of-Low-Rate 72-Second Schedule of Reinforcement. Open Neuropsychopharmacol J. 2008 Jan 01; 1:24-32. PMID: 20352018.
      View in: PubMed
    14. Scott-McKean, J.J., Wenger, G.R., Tecott, L.H., and Costa, A.C.S., Scott-McKean, J.J., Tecott, L.H., and Costa, A.C.S. 5HT1A receptor null mutant mice responding under a differential-reinforcement-of-low-rate 72-second schedule of reinforcement. The Open Neuropsychopharmacology Journal. 2008; 1(1):24-32 (PMID:20352018).
    15. Wenger GR. Diazepam and scopolamine decrease working memory performance in alcohol preferring and non-preferring rats. Alcoholism Clin Exp Res. 2008.
    16. Dowdy-Sanders NC, Wenger GR. Effect of d-amphetamine?SO4 on learning in Ts65Dn, a murine model of Down syndrome, at 20-months of age. FASEB J. 2007.
    17. Wenger GR. Effect of ethanol on working memory in rats selectively bred for ethanol preference. Behav Pharmacology. 2007.
    18. Dowdy-Sanders NC, Wenger GR. Effect of d-amphetamine on learning in the Ts65Dn, a mouse model of Down syndrome. FASEB J. 2006.
    19. Wenger GR. U50,488 Discrimination in C57BL/6J, DBA2/J and 129SvImJ mice. FASEB J. 2006.
    20. Wenger GR, Hall CJ. Ethanol effects on motivation to lever press for food in alcohol preferring and non-preferring rats. Alcoholism Clin. Exp. Res. 2006.
    21. Dowdy-Sanders NC, Wenger GR. Working memory in the Ts65Dn mouse, a model for Down syndrome. Behav Brain Res. 2006 Apr 03; 168(2):349-52. PMID: 16386318.
      View in: PubMed
    22. Wenger GR. The effects of ethanol on memory and learning in P and NP rats. Behav Pharmacology. 2005.
    23. Wenger GR, Schmidt C, Davisson MT. Operant conditioning in the Ts65Dn mouse: learning. Behav Genet. 2004 Jan; 34(1):105-19. PMID: 14739701.
      View in: PubMed
    24. Dienel GA, Cruz NF, Ball K, Popp D, Gokden M, Baron S, Wright D, Wenger GR. Behavioral training increases local astrocytic metabolic activity but does not alter outcome of mild transient ischemia. Brain Res. 2003 Jan 31; 961(2):201-12. PMID: 12531487.
      View in: PubMed
    25. Hardin JS, Wessinger WD, Wenger GR, Proksch JW, Laurenzana EM, Owens SM. A single dose of monoclonal anti-phencyclidine IgG offers long-term reductions in phencyclidine behavioral effects in rats. J Pharmacol Exp Ther. 2002 Jul; 302(1):119-26. PMID: 12065708.
      View in: PubMed
    26. Lemmonds CA, Williams DK, Wenger GR. Effect of pentobarbital, d-amphetamine, and nicotine on two models of sustained attention in pigeons. Psychopharmacology (Berl). 2002 Oct; 163(3-4):391-8. PMID: 12373439.
      View in: PubMed
    27. Wenger GR. Effects of ethanol on the titrating delayed matching-to-position performance in P and NP rats. Alcoholism Clin Exp Res. 2002.
    28. Wenger GR. Effects of ethanol and other drugs of abuse on attention in rats. Drug and Alcohol Dependence. 2001.
    29. Dayer CA, Light KE, Wenger GR. The effect of ethanol on sustained attention and short-term memory in the pigeon. FASEB J. 1999.
    30. Wenger GR. Drugs and Athletes. CNS stimulants and athletic performance. 1998; 1988.
    31. Cory-Slechta DA, Henderson R, Bakshi K, Wenger GR, Et al. Abstracts of the Workshop on Risk Assessment Based on Neurochemical Changes. Inhalation Toxicology. 1997; 9:157-180.
    32. Wenger GR, Hudzik T, Moore E, Wright DW. Pentobarbital, diazepam and phencyclidine disrupt delayed matching performance: interactions with picrotoxin in pigeons and squirrel monkeys. Behav Pharmacol. 1996; 7(4):384 - 394 (PMID:11224432).
    33. Wenger GR, McMillan DE, Moore E, Williamson AP. Disruption of temporal discrimination by drugs of abuse: I. Unmasking of a color bias. Behav Pharmacol. 1995; 6(4):297 - 310 (PMID:11224339).
    34. Wenger GR. Neurobehavioral Toxicity: Analysis and Interpretation. The use of schedule-controlled behavior in toxicity testing. 1994; 215-226.
    35. McMillan DE, Wright DW, Wenger GR. Effects of phencyclidine-like drugs on responding under multiple fixed ratio, fixed interval schedules. Behav Pharmacol. 1992; 3(2):143 - 147 (PMID:11224112).
    36. McMillan DE, Wessinger WD, Paule MG, Wenger GR. Interoceptive drug discrimination and exteroceptive light discrimination: A comparison under similar conditions in the pigeon. Pharmacol Biochem Behav. 1989; 34:641-647.
    37. Wenger GR. Modern Pharmacology. Antianxiety Drugs. 1986; 521-532.
    38. Wenger GR. Behavioral Pharmacology: The Current Status. The effects of trialkyl tin compounds on schedule-controlled behavior. 1985; 503-518.
    39. Dewis PB, Wenger GR. Test Methods for Definitions of Effects of Toxic Substances on Behavior and Neuromotor Function. Testing for behavioral effects of agents. 1979; 119-127.
    40. Wenger GR. Advances in Behavioral Pharmacology, Vol. 2. Some quantitative behavioral pharmacology in the mouse. 1979; 1-38.
    41. Dews PB, Wenger GR. Advances in Behavioral Pharmacology, Vol 1. Rate-dependency of the behavioral effects of amphetamine. 1977; 167-227.
    42. Bronaugh RL, Wenger GR, Garver DL, Rutledge CO. Effect of carbidopa on the metabolism of L-dopa in the pigtail monkey. Biochem Pharmacol. 1976; 25(14):1679 - 1681 (PMID:821489).
    43. Wenger GR, Stitzel RE, Craig CR. The role of biogenic amines in the reserpine-induced alteration of minimal electroshock seizure thresholds in the mouse. Neuropharmacology. 1973; 12(7):693 - 703 (PMID:4147164).
    44. Wenger GR. Impulsivity does not correlate with working memory or alcohol preference in rats bred for alcohol preference. College on Problems of Drug Dependence 2009.
    45. Wenger GR, Sellers EA. Responding of C57BL/6J, DBA/2J and 129 Mice Under a Multiple Schedule of Reinforcement Following Mu, Kappa, and Delta Agonists.
    46. Wenger GR, Dowdy N, Davisson MT, Schmidt C. Delayed matching-to-position performance in Ts65Dn and littermate control mice. The Expert Workshop on the Biology of Chromosome 21 Genes.
    47. Wenger GR, Somers J. Effects of opioid receptor specific agonists in C57BL/6J, DBA/2J and 129/SvImJ mice responding under a mult FR30 FI600 schedule of milk presentation. Experimental Biology 2004.
    48. Hardin JS, Wenger GR, Wessinger WD, Owens SM. Monoclonal antibodies as long-term antagonists of phencyclidine (PCP). American Society for Clinical Pharmacology and Therapeutics.
    49. Sanders NC, Williams DK, Wenger GR. Effect of d-Amphetamine on Learning in a Mouse Model of Down Syndrome. Behav Brain Research.
    50. Wenger GR. Opioid Drug Discrimination in C57BL/6J, DBA/2J, and 129SvImJ mice. College on Problems of Drug Dependence 2005.
    51. Wenger GR. Drug effects on food maintained progressive-ratio performance in P and NP rats. Annual meeting of the Research Society on Alcoholism.
    52. Wenger GR. Repeated acquisition performance in P and NP rats: Effects of ethanol. Experimental Biology.
    53. Dowdy NC, Wenger GR. The effect of nicotine on the Ts65Dn, a mouse model for Down syndrome. Experimental Biology 2005.
    54. Li X, Sieghart W, Wenger GR, Cook J. Synthesis, in vitro affinity and efficacy of the first bivalent a5 subtype selective BzR/GABAA antagonist. American Chemical Society.
    55. Wenger GR. The effect of ethanol on working memory and repeated learning in Wistar rats. College on Problems of Drug Dependence 2007.
    56. Wenger GR. Effects of Ethanol, Diazepam and Scopolamine on Temporal Discrimination in P and NP Rats. Experimental Biology.
    57. Wenger GR. Learning in the Ts65Dn Mouse. Behavioral Pharmacology Society.
    58. Wenger GR. Effects of Ethanol, Diazepam and Scopolamine on Temporal Discrimination in P and NP Rats. Experimental Biology.
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