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Stephanie Byrum

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentBiochemistry & Molecular Biology, College of Medicine
AddressB406 Biomedical Research I
325 S. Elm St.
Mail Slot # 516
Little Rock AR 72205
Phone501-603-1224
ORCID ORCID Icon0000-0002-1783-3610 Additional info
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    Other Roles
    Director of UAMS Bioinformatics Core
    Arkansas INBRE social media coordinator
    Director of ACRI CTPR Proteogenomics Core
    Director of Bioinformatics for the IDeA National Resource for Quantitative Proteomics

    Collapse Overview 
    Collapse overview
    My research focus involves a translational approach for the identification of cancer systems biology, from the bench to the bedside. I have performed experiments ranging from collecting patient samples, to performing proteomic and genomic analyses, using bioinformatics to mine large complex data sets, and identify important clinical markers for metastatic breast cancer and melanoma. I have formal training in bioinformatics and mass spectrometry.
    My bioinformatics skill set includes: proteomics (label-free, stable isotope tags, SILAC, TMT-labeling, intensity-based analysis), epigenetics (quantitation of histone posttranslational modifications and chromatin remodelers), genomics (microarray, ChIP-seq, RNA-seq), metagenomics, biostatistics and data mining, and pathway and functional analysis. My research is currently focused on developing multi-omics data integration and proteogenomics applications.


    Collapse Affiliation 
    Collapse member of
    American Society for Mass Spectrometry
    International Society for Computational Biology

    Collapse Research 
    Collapse research activities and funding
    R01DK139476     (MACNICOL, MELANIE)Sep 18, 2024 - May 31, 2029
    NIH/National Institutes of Health
    Molecular mechanisms of pituitary plasticity
    Role: Co-Investigator
    1946391     (PRIOR, FRED)May 1, 2024 - Aug 31, 2024
    National Science Foundation - Pass Through: Arkansas Economic Development Commission
    DART Summer Undergraduate Research Experience-Autumn Gault
    Role: Co-Investigator
    1946391     (PRIOR, FRED)Jul 1, 2023 - Aug 31, 2024
    National Science Foundation - Pass Through: Arkansas Economic Development Commission
    Robust and Trusted Data Analytics (DART)
    Role: Principal Investigator
    GR034233     (BYRUM, STEPHANIE D)Jan 1, 2023 - Dec 31, 2023
    UAMS ACHRI Flow Through
    ACRI Bryum GR034233
    Role: Principal Investigator
    P20GM121293     (BYRD, ALICIA K)Jul 1, 2022 - Jun 30, 2027
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: Arkansas Children's Research Institute
    Role of HELB in the Replication Stress Response Dr. Tacketts COBRA through ACRI
    Role: Co-Investigator
    OIA-1946391     (PRIOR, FRED)Jul 1, 2022 - Aug 31, 2023
    National Science Foundation - Pass Through: Arkansas Economic Development Commission
    Robust and Trusted Data Analytics: From Smart Curation to Socially Aware Decision Making (Area 1, Coordinated Data Science Cyber Infrastructure) Year 3
    Role: Principal Investigator
    R01GM141040     (LUPU, FLOREA)Sep 10, 2021 - Aug 31, 2025
    NIH
    Discovery and Characterization of Novel Sepsis Proteome Biomarkers
    Role: Co-Investigator
    R01DK127723     (CHILDS, GWEN V)Jul 17, 2021 - Jun 30, 2025
    NIH
    The Impact of Obesity on Somatotrope Function
    Role: Co-Investigator
    R24GM137786     (TACKETT, ALAN)Aug 20, 2020 - May 31, 2025
    NIH
    IDeA National Resource for Quantitative Proteomics
    Role: Co-Investigator
    1946391     (Steve Stanley)Jul 1, 2020 - Jun 30, 2025
    NSF
    RII Track-1: Data Analytics that are Robust and Trusted (DART): From Smart Curation to Socially Aware Decision Making
    Role Description: The DART research program will create a consortium of Arkansas researchers with a synergistic, integrated focus on excellence in data analytics research
    Role: Co-Investigator
    R01ES030323     (BLOSSOM, SARAH J)Mar 1, 2020 - Dec 31, 2025
    NIH
    Epigenetic modulation of CD4+ T cell differentiation and autoimmunity by trichloroethylene
    Role: Co-Investigator
    R01HL150194     (FARRAR, JASON ELI)Feb 15, 2020 - Jan 31, 2024
    NIH
    Mechanisms of Erythroid Remission in Diamond Blackfan Anemia (DBA)
    Role: Co-Investigator
    GR037129     (BYRUM, STEPHANIE D)Jul 1, 2019 - Jun 30, 2020
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    R01CA236209     (TACKETT, ALAN)Jun 15, 2019 - May 31, 2024
    NIH
    Identification of Druggable Targets to Complement Melanoma Therapy
    Role: Co-Investigator
    Seeds of Science FY19     (BYRD, ALICIA K)Feb 1, 2019 - Jan 31, 2020
    UAMS Internal Research Awards
    Seeds of Science Pilot award
    Role: Principal Investigator
    R01HD093461     (CHILDS, GWEN V;MACNICOL, ANGUS M ;MACNICOL, MELANIE C)Sep 1, 2018 - Jun 30, 2024
    NIH
    Control of pituitary cell plasticity through regulated mRNA translation
    Role: Co-Investigator
    ACRI # 033006     (BYRUM, STEPHANIE D)Jun 1, 2018 - May 31, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    R35GM122601     (RANEY, KEVIN DOUGLAS)May 1, 2017 - Apr 30, 2022
    NIH
    Functions and Mechanisms of Helicases and G-Quadruplex Nucleic Acids
    Role: Co-Investigator
    R01GM118760     (TACKETT, ALAN J)Mar 1, 2017 - Jan 31, 2022
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: Johns Hopkins University
    Epigenetic profiling and enzymatic regulation of H3K23me3 during cellular differentiation - Continuation - Continuation - Continuation
    Role: Co-Investigator
    OIA     (LARSON-PRIOR, LINDA)Sep 1, 2016 - Aug 31, 2020
    National Science Foundation - Pass Through: Louisiana Tech University
    RII Track-2 FEC- Probing and Understanding the Brain: Micro and Macro Dynamics of Seizure and Memory Networks
    Role: Principal Investigator
    R21DA041822     (TACKETT, ALAN)Jul 1, 2016 - Jun 30, 2019
    NIH
    Technology for Identification of Epiproteomes in Tissue Samples
    Role: Co-Investigator
    R01GM117439     (RANEY, KEVIN DOUGLAS)Sep 21, 2015 - Jun 30, 2019
    NIH
    G-quadruplex DNA as a chemical signaling agent
    Role: Co-Investigator
    R01AI119380     (SMELTZER, MARK S)Jun 15, 2015 - Aug 31, 2026
    NIH
    Defining the role of post-translational regulation by extracellular proteases in the pathogenesis of Staphylococcus aureus osteomyelitis
    Role: Co-Investigator
    NCC 9-58 95     (BOERMA, MARJAN)Jun 1, 2014 - May 31, 2017
    National Space Biomedical Research Institute
    Center for Research on Cardiac and Vascular Effects of Space Radiation
    Role: Co-Investigator
    F32GM093614     (BYRUM, STEPHANIE)Mar 3, 2011 - Mar 2, 2013
    NIH
    Identification of combinatorial histone post-translational modifications within t
    Role: Principal Investigator
    P30RR031154     (TACKETT, ALAN J)Sep 1, 2010 - May 31, 2015
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: University of Arkansas at Fayetteville
    NIH COBRE Center for Protein Structure and Function
    Role: Co-Investigator
    R01DA025755     (TACKETT, ALAN JACKSON)Sep 20, 2008 - Jul 31, 2013
    NIH
    Development of technology for high resolution epigenetic profiling of chromatin
    Role: Co-Investigator

    Collapse Bibliographic 
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    The links below are provided by the researcher to provide access to external online bibliographies that they keep independently from the Profiles System.
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Fry LG, Washam CL, Roys H, Bowlin AK, Venugopal G, Bird JT, Byrum SD, Weinkopff T. HIF-a signaling regulates the macrophage inflammatory response during Leishmania major infection. bioRxiv. 2024 Aug 27. PMID: 39253467.
      View in: PubMed
    2. Richardson KK, Adam GO, Ling W, Warren A, Marques-Carvalho A, Thostenson JD, Krager K, Aykin-Burns N, Byrum SD, Almeida M, Kim HN. Mitochondrial protein deacetylation by SIRT3 in osteoclasts promotes bone resorption with aging in female mice. Mol Metab. 2024 Oct; 88:102012. PMID: 39154858.
      View in: PubMed
    3. Bolin EH, Mourani PM, Byrum SD, Mackintosh SG, Dossey AM, Angtuaco MJ, Zakaria D, Greiten LE, Strub GM, Zhang H, Richter GT. Quantitative plasma proteomic analysis in children after superior cavopulmonary anastomosis with pulmonary arteriovenous malformations. Pediatr Res. 2024 Aug 12. PMID: 39134758.
      View in: PubMed
    4. Fry L, Roys H, Bowlin A, Venugopal G, Bird JT, Weaver A, Byrum SD, Weinkopff T. Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis. bioRxiv. 2024 Aug 07. PMID: 39211126.
      View in: PubMed
    5. Tandon I, Woessner AE, Ferreira LA, Shamblin C, Vaca-Diez G, Walls A, Kuczwara P, Applequist A, Nascimento DF, Tandon S, Kim JW, Rausch M, Timek T, Padala M, Kinter MT, Province D, Byrum SD, Quinn KP, Balachandran K. A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression. Acta Biomater. 2024 Sep 15; 186:167-184. PMID: 39084496.
      View in: PubMed
    6. O'Connell KA, Kopchick B, Carlson T, Belardo D, Byrum SD. Understanding proteome quantification in an interactive learning module on Google Cloud Platform. Brief Bioinform. 2024 Jul 23; 25(Supplement_1). PMID: 39041914.
      View in: PubMed
    7. Hong A, Piva M, Liu S, Hugo W, Lomeli SH, Zoete V, Randolph CE, Yang Z, Wang Y, Lee JJ, Lo SJ, Sun L, Vega-Crespo A, Garcia AJ, Shackelford DB, Dubinett SM, Scumpia PO, Byrum SD, Tackett AJ, Donahue TR, Michielin O, Holmen SL, Ribas A, Moriceau G, Lo RS. Expression of Concern: Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity. Cancer Discov. 2024 07 01; 14(7):1357. PMID: 38946326.
      View in: PubMed
    8. Pechous RD, Malaviarachchi PA, Banerjee SK, Byrum SD, Alkam DH, Ghaffarieh A, Kurten RC, Kennedy JL, Zhang X. An ex vivo human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy. J Virol. 2024 Jul 23; 98(7):e0079424. PMID: 38940558.
      View in: PubMed
    9. Choudhury SR, Byrum SD, Blossom SJ. Trichloroethylene metabolite modulates DNA methylation-dependent gene expression in Th1-polarized CD4+ T cells from autoimmune-prone mice. Toxicol Sci. 2024 May 28; 199(2):289-300. PMID: 38518092.
      View in: PubMed
    10. Biedka S, Alkam D, Washam CL, Yablonska S, Storey A, Byrum SD, Minden JS. One-pot method for preparing DNA, RNA, and protein for multiomics analysis. Commun Biol. 2024 Mar 14; 7(1):324. PMID: 38485785.
      View in: PubMed
    11. McCrury M, Swafford K, Shuttleworth SL, Mehdi SH, Acharya B, Saha D, Naceanceno K, Byrum SD, Storey AJ, Xu YZ, Doshier C, Patel V, Post GR, De Loose A, Rodriguez A, Shultz LD, Zhan F, Yoon D, Frett B, Kendrick S. Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma. Mol Cancer Ther. 2024 Mar 04; 23(3):316-329. PMID: 37816504.
      View in: PubMed
    12. Loveland-Jones C, Gaughan J, Caudle A, Murphy B, Samiian L, Byrum S, Brill K, Germaine P, Zhang X, Yoon-Flannery K, Carter T, Lopez A, Gruner R, Fantazzio M, Kuerer H. Evaluation of traditional targeted axillary dissection eligibility criteria for node-positive breast cancer after neoadjuvant chemotherapy in a prospective multicenter registry. Eur J Surg Oncol. 2024 Apr; 50(4):108245. PMID: 38484493.
      View in: PubMed
    13. Miles TK, Allensworth-James ML, Odle AK, Silva Moreira AR, Haney AC, LaGasse AN, Gies AJ, Byrum SD, Riojas AM, MacNicol MC, MacNicol AM, Childs GV. Maternal undernutrition results in transcript changes in male offspring that may promote resistance to high fat diet induced weight gain. Front Endocrinol (Lausanne). 2023; 14:1332959. PMID: 38720938.
      View in: PubMed
    14. Garg S, Morehead LC, Bird JT, Graw S, Gies A, Storey AJ, Tackett AJ, Edmondson RD, Mackintosh SG, Byrum SD, Miousse IR. Characterization of methionine dependence in melanoma cells. Mol Omics. 2024 Jan 15; 20(1):37-47. PMID: 37782107.
      View in: PubMed
    15. Chappell K, Byrum SD. Understanding PTM Cross Talk Through a Visualization Tool, PTMViz. Methods Mol Biol. 2024; 2836:57-65. PMID: 38995535.
      View in: PubMed
    16. Miles TK, Odle AK, Byrum SD, Lagasse A, Haney A, Ortega VG, Bolen CR, Banik J, Reddick MM, Herdman A, MacNicol MC, MacNicol AM, Childs GV. Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism. Endocrinology. 2023 Dec 23; 165(2). PMID: 38103263.
      View in: PubMed
    17. Zhao S, Lu J, Pan B, Fan H, Byrum SD, Xu C, Kim A, Guo Y, Kanchi KL, Gong W, Sun T, Storey AJ, Burkholder NT, Mackintosh SG, Kuhlers PC, Edmondson RD, Strahl BD, Diao Y, Tackett AJ, Raab JR, Cai L, Song J, Wang GG. TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons. Nature. 2023 Nov; 623(7987):633-642. PMID: 37938770.
      View in: PubMed
    18. Hashimi M, Sebrell TA, Hedges JF, Snyder D, Lyon KN, Byrum SD, Mackintosh SG, Crowley D, Cherne MD, Skwarchuk D, Robison A, Sidar B, Kunze A, Loveday EK, Taylor MP, Chang CB, Wilking JN, Walk ST, Schountz T, Jutila MA, Bimczok D. Antiviral responses in a Jamaican fruit bat intestinal organoid model of SARS-CoV-2 infection. Nat Commun. 2023 10 28; 14(1):6882. PMID: 37898615.
      View in: PubMed
    19. Todorova VK, Byrum SD, Mackintosh SG, Jamshidi-Parsian A, Gies AJ, Washam CL, Jenkins SV, Spiva T, Bowman E, Reyna NS, Griffin RJ, Makhoul I. Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells. Int J Mol Sci. 2023 Aug 23; 24(17). PMID: 37685904.
      View in: PubMed
    20. Chen M, Li J, Zhang L, Wang L, Cheng C, Ji H, Altilia S, Ding X, Cai G, Altomare D, Shtutman M, Byrum SD, Mackintosh SG, Feoktistov A, Soshnikova N, Mogila VA, Tatarskiy V, Erokhin M, Chetverina D, Prawira A, Ni Y, Urban S, McInnes C, Broude EV, Roninson IB. CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins. Nucleic Acids Res. 2023 08 11; 51(14):7288-7313. PMID: 37378433.
      View in: PubMed
    21. Moreira ARS, Lim J, Urbaniak A, Banik J, Bronson K, Lagasse A, Hardy L, Haney A, Allensworth M, Miles TK, Gies A, Byrum SD, Wilczynska A, Boehm U, Kharas M, Lengner C, MacNicol MC, Childs GV, MacNicol AM, Odle AK. Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle. Endocrinology. 2023 08 01; 164(9). PMID: 37477898.
      View in: PubMed
    22. Seman A, Chandra PK, Byrum SD, Mackintosh SG, Gies AJ, Busija DW, Rutkai I. Targeting mitochondria in the aged cerebral vasculature with SS-31, a proteomic study of brain microvessels. Geroscience. 2023 10; 45(5):2951-2965. PMID: 37458933.
      View in: PubMed
    23. Liu S, Wu J, Stolarz A, Zhang H, Boerma M, Byrum SD, Rusch NJ, Ding Z. PCSK9 attenuates efferocytosis in endothelial cells and promotes vascular aging. Theranostics. 2023; 13(9):2914-2929. PMID: 37284459.
      View in: PubMed
    24. Venugopal G, Bird JT, Roys H, Bowlin A, Fry L, Byrum SD, Weinkopff T. BOTH THE INFECTION STATUS AND INFLAMMATORY MICROENVIRONMENT INDUCE TRANSCRIPTIONAL REMODELING IN MACROPHAGES IN MURINE LEISHMANIAL LESIONS. J Parasitol. 2023 05 01; 109(3):200-210. PMID: 37270767.
      View in: PubMed
    25. Sun RW, Zhang H, Mehdi SJ, Richter GT, Bowman HH, Sifford J, Smith C, Burnett AK, Layman A, Washam CL, Byrum SD, Bennett JT, Jensen DM, Dmyterko V, Perkins JA, Shawber CJ, Wu JK, Strub GM. Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4. J Invest Dermatol. 2023 10; 143(10):2085-2089.e1. PMID: 37088278.
      View in: PubMed
    26. Pechous RD, Malaviarachchi PA, Banerjee SK, Byrum SD, Alkam DH, Ghaffarieh A, Kurten RC, Kennedy JL, Zhang X. An ex vivo human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy. bioRxiv. 2023 Apr 19. PMID: 37131640.
      View in: PubMed
    27. Garg S, Morehead LC, Bird JT, Graw S, Gies A, Storey AJ, Tackett AJ, Edmondson RD, Mackintosh SG, Byrum SD, Miousse IR. Characterization of methionine dependence in melanoma cells. bioRxiv. 2023 Apr 05. PMID: 37066392.
      View in: PubMed
    28. Avaritt NL, Byrum SD. Cutting-Edge Technologies Driving Quantitative Mass Spectrometry. J Vis Exp. 2023 03 03; (193). PMID: 37602860.
      View in: PubMed
    29. Wong L, Randolph C, Kanwischer E, Ingold A, Boyanton BL, Taylor J, Frenner RA, Harley SE, Bird JT, Thurman TJ, Kandel S, Ussery DW, Byrum SD, Dinwiddie D, Domman D, Chalwadi UK, Kennedy J. Severe Acute Respiratory Syndrome Coronavirus-2 Lambda Variant Collected from a Child from Arkansas and Sequenced. Microbiol Resour Announc. 2023 Mar 16; 12(3):e0000723. PMID: 36779742.
      View in: PubMed
    30. Roy Choudhury S, Byrum SD, Alkam D, Ashby C, Zhan F, Tackett AJ, Van Rhee F. Expression of integrin ?-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics. Clin Epigenetics. 2023 02 04; 15(1):18. PMID: 36737807.
      View in: PubMed
    31. Batts TL, Sasaki E, Miller M, Sparago J, Bauer RW, Paulsen D, Boudreaux B, Liu CC, Byrum SD, Johnston AN. Neoplastic signatures: Comparative proteomics of canine hepatobiliary neuroendocrine tumors to normal niche tissue. PLoS One. 2023; 18(1):e0280928. PMID: 36696389.
      View in: PubMed
    32. Flores VV, Hernandez Gifford JA, Soto-Navarro SA, Matera J, Wilson BK, Hartson S, Byrum SD, Gifford CA. Calves severely affected by bovine respiratory disease have reduced protection against histone toxicity and exhibit lower complement activity. J Anim Sci. 2023 Jan 03; 101. PMID: 37410397.
      View in: PubMed
    33. Hashimi M, Sebrell T, Hedges J, Snyder D, Lyon K, Byrum S, Mackintosh SG, Cherne M, Skwarchuk D, Crowley D, Robison A, Sidar B, Kunze A, Loveday E, Taylor M, Chang C, Wilking J, Walk S, Schountz T, Jutila M, Bimczok D. Antiviral response mechanisms in a Jamaican Fruit Bat intestinal organoid model of SARS-CoV-2 infection. Res Sq. 2022 Dec 12. PMID: 36561186.
      View in: PubMed
    34. Chau MJ, Quintero JE, Blalock E, Byrum S, Mackintosh SG, Samaan C, Gerhardt GA, van Horne CG. Transection injury differentially alters the proteome of the human sural nerve. PLoS One. 2022; 17(11):e0260998. PMID: 36417411.
      View in: PubMed
    35. Zhang Y, Gabere M, Taylor MA, Simoes CC, Dumbauld C, Barro O, Tesfay MZ, Graham AL, Ferdous KU, Savenka AV, Chamcheu JC, Washam CL, Alkam D, Gies A, Byrum SD, Conti M, Post SR, Kelly T, Borad MJ, Cannon MJ, Basnakian A, Nagalo BM. Repurposing live attenuated trivalent MMR vaccine as cost-effective cancer immunotherapy. Front Oncol. 2022; 12:1042250. PMID: 36457491.
      View in: PubMed
    36. Zuniga O, Byrum S, Wolfe AR. Discovery of the inhibitor of DNA binding 1 as a novel marker for radioresistance in pancreatic cancer using genome-wide RNA-seq. Cancer Drug Resist. 2022; 5(4):926-938. PMID: 36627902.
      View in: PubMed
    37. Scieszka D, Byrum SD, Mackintosh SG, Madison M, Knight J, Campen MJ, Kheradmand F. Subchronic Electronic Cigarette Exposures Have Overlapping Protein Biomarkers with Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2022 10; 67(4):503-506. PMID: 36178855.
      View in: PubMed
    38. Venugopal G, Bird JT, Washam CL, Roys H, Bowlin A, Byrum SD, Weinkopff T. In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution. PLoS Negl Trop Dis. 2022 07; 16(7):e0010518. PMID: 35789215.
      View in: PubMed
    39. Barbosa P, Landes RD, Graw S, Byrum SD, Bennuri S, Delhey L, Randolph C, MacLeod S, Reis A, B?rsheim E, Rose S, Carvalho E. Effect of excess weight and insulin resistance on DNA methylation in prepubertal children. Sci Rep. 2022 05 19; 12(1):8430. PMID: 35589784.
      View in: PubMed
    40. Li D, Yu X, Kottur J, Gong W, Zhang Z, Storey AJ, Tsai YH, Uryu H, Shen Y, Byrum SD, Edmondson RD, Mackintosh SG, Cai L, Liu Z, Aggarwal AK, Tackett AJ, Liu J, Jin J, Wang GG. Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic. Oncogene. 2022 06; 41(24):3328-3340. PMID: 35525905.
      View in: PubMed
    41. Vazquez JH, Kennon-McGill S, Byrum SD, Mackintosh SG, Jaeschke H, Williams DK, Lee WM, Dranoff JA, McGill MR. Proteomics Indicates Lactate Dehydrogenase Is Prognostic in Acetaminophen-Induced Acute Liver Failure Patients and Reveals Altered Signaling Pathways. Toxicol Sci. 2022 04 26; 187(1):25-34. PMID: 35172013.
      View in: PubMed
    42. Robeson MS, Manna K, Randolph C, Byrum S, Hakkak R. Short-Term Metformin Treatment Enriches Bacteroides dorei in an Obese Liver Steatosis Zucker Rat Model. Front Microbiol. 2022; 13:834776. PMID: 35432282.
      View in: PubMed
    43. Kaufmann Y, Byrum SD, Acott AA, Siegel ER, Washam CL, Klimberg VS, Mancino AT. Proteomic profiling of tear fluid as a promising non-invasive screening test for colon cancer. Am J Surg. 2022 07; 224(1 Pt A):19-24. PMID: 35354531.
      View in: PubMed
    44. Lin VJT, Hu J, Zolekar A, Salick MR, Mittal P, Bird JT, Hoffmann P, Kaykas A, Byrum SD, Wang YC. Deficiency of N-glycanase 1 perturbs neurogenesis and cerebral development modeled by human organoids. Cell Death Dis. 2022 03 24; 13(3):262. PMID: 35322011.
      View in: PubMed
    45. Todorova VK, Byrum SD, Gies AJ, Haynie C, Smith H, Reyna NS, Makhoul I. Circulating Exosomal microRNAs as Predictive Biomarkers of Neoadjuvant Chemotherapy Response in Breast Cancer. Curr Oncol. 2022 01 28; 29(2):613-630. PMID: 35200555.
      View in: PubMed
    46. Richardson KK, Ling W, Krager K, Fu Q, Byrum SD, Pathak R, Aykin-Burns N, Kim HN. Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice. Int J Mol Sci. 2022 Jan 08; 23(2). PMID: 35054859.
      View in: PubMed
    47. Bettadapura M, Roys H, Bowlin A, Venugopal G, Washam CL, Fry L, Murdock S, Wanjala H, Byrum SD, Weinkopff T. HIF-a Activation Impacts Macrophage Function during Murine Leishmania major Infection. Pathogens. 2021 Dec 06; 10(12). PMID: 34959539.
      View in: PubMed
    48. Groves T, Corley C, Byrum SD, Allen AR. The Effects of 5-Fluorouracil/Leucovorin Chemotherapy on Cognitive Function in Male Mice. Front Mol Biosci. 2021; 8:762116. PMID: 34778377.
      View in: PubMed
    49. Rosa F, Zybailov BL, Glazko GV, Rahmatallah Y, Byrum S, Mackintosh SG, Bowlin AK, Yeruva L. Milk Formula Diet Alters Bacterial and Host Protein Profile in Comparison to Human Milk Diet in Neonatal Piglet Model. Nutrients. 2021 Oct 22; 13(11). PMID: 34835974.
      View in: PubMed
    50. Paidi SK, Rodriguez Troncoso J, Raj P, Monterroso Diaz P, Ivers JD, Lee DE, Avaritt NL, Gies AJ, Quick CM, Byrum SD, Tackett AJ, Rajaram N, Barman I. Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy. Cancer Res. 2021 11 15; 81(22):5745-5755. PMID: 34645610.
      View in: PubMed
    51. Chappell K, Manna K, Washam CL, Graw S, Alkam D, Thompson MD, Zafar MK, Hazeslip L, Randolph C, Gies A, Bird JT, Byrd AK, Miah S, Byrum SD. Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer. Mol Omics. 2021 10 11; 17(5):677-691. PMID: 34142686.
      View in: PubMed
    52. Delgado M, Washam CL, Urbaniak A, Heflin B, Storey AJ, Lan RS, Mackintosh SG, Tackett AJ, Byrum SD, Chambers TC. Phosphoproteomics Provides Novel Insights into the Response of Primary Acute Lymphoblastic Leukemia Cells to Microtubule Depolymerization in G1 Phase of the Cell Cycle. ACS Omega. 2021 Sep 28; 6(38):24949-24959. PMID: 34604676.
      View in: PubMed
    53. Xu C, Meng F, Park KS, Storey AJ, Gong W, Tsai YH, Gibson E, Byrum SD, Li D, Edmondson RD, Mackintosh SG, Vedadi M, Cai L, Tackett AJ, Kaniskan H?, Jin J, Wang GG. A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells. Cell Chem Biol. 2022 03 17; 29(3):386-397.e9. PMID: 34469831.
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    54. Wang Y, Liu S, Yang Z, Algazi AP, Lomeli SH, Wang Y, Othus M, Hong A, Wang X, Randolph CE, Jones AM, Bosenberg MW, Byrum SD, Tackett AJ, Lopez H, Yates C, Solit DB, Ribas A, Piva M, Moriceau G, Lo RS. Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy. Cancer Cell. 2021 10 11; 39(10):1375-1387.e6. PMID: 34416167.
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    55. Ahn JH, Davis ES, Daugird TA, Zhao S, Quiroga IY, Uryu H, Li J, Storey AJ, Tsai YH, Keeley DP, Mackintosh SG, Edmondson RD, Byrum SD, Cai L, Tackett AJ, Zheng D, Legant WR, Phanstiel DH, Wang GG. Phase separation drives aberrant chromatin looping and cancer development. Nature. 2021 07; 595(7868):591-595. PMID: 34163069.
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    56. Chappell K, Graw S, Washam CL, Storey AJ, Bolden C, Peterson EC, Byrum SD. PTMViz: a tool for analyzing and visualizing histone post translational modification data. BMC Bioinformatics. 2021 May 26; 22(1):275. PMID: 34039258.
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    57. Xu C, Tsai YH, Galbo PM, Gong W, Storey AJ, Xu Y, Byrum SD, Xu L, Whang YE, Parker JS, Mackintosh SG, Edmondson RD, Tackett AJ, Huang J, Zheng D, Earp HS, Wang GG, Cai L. Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer. Nucleic Acids Res. 2021 05 21; 49(9):4971-4988. PMID: 33849067.
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    58. Fan H, Guo Y, Tsai YH, Storey AJ, Kim A, Gong W, Edmondson RD, Mackintosh SG, Li H, Byrum SD, Tackett AJ, Cai L, Wang GG. A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing. Nucleic Acids Res. 2021 05 07; 49(8):4441-4455. PMID: 33823544.
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    59. Schinke CD, Bird JT, Qu P, Yaccoby S, Lyzogubov VV, Shelton R, Ling W, Boyle EM, Deshpande S, Byrum SD, Washam C, Mackintosh S, Stephens O, Thanendrarajan S, Zangari M, Shaughnessy J, Zhan F, Barlogie B, van Rhee F, Walker BA. PHF19 inhibition as a therapeutic target in multiple myeloma. Curr Res Transl Med. 2021 07; 69(3):103290. PMID: 33894670.
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    60. Graw S, Chappell K, Washam CL, Gies A, Bird J, Robeson MS, Byrum SD. Multi-omics data integration considerations and study design for biological systems and disease. Mol Omics. 2021 04 19; 17(2):170-185. PMID: 33347526.
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    61. Reed MR, Maddukuri L, Ketkar A, Byrum SD, Zafar MK, Bostian ACL, Tackett AJ, Eoff RL. Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells. NAR Cancer. 2021 Jun; 3(2):zcab014. PMID: 33870196.
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    62. Brown T, McElroy T, Simmons P, Walters H, Ntagwabira F, Wang J, Byrum SD, Allen AR. Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide. Brain Res. 2021 06 01; 1760:147397. PMID: 33705788.
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    63. Wallis KF, Morehead LC, Bird JT, Byrum SD, Miousse IR. Differences in cell death in methionine versus cysteine depletion. Environ Mol Mutagen. 2021 03; 62(3):216-226. PMID: 33615565.
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    64. Allensworth-James M, Banik J, Odle A, Hardy L, Lagasse A, Moreira ARS, Bird J, Thomas CL, Avaritt N, Kharas MG, Lengner CJ, Byrum SD, MacNicol MC, Childs GV, MacNicol AM. Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi. Endocrinology. 2021 03 01; 162(3). PMID: 33373440.
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    65. Jenkins SV, Alimohammadi M, Terry AS, Griffin RJ, Tackett AJ, Leung JW, Vang KB, Byrum SD, Dings RPM. Dysbiotic stress increases the sensitivity of the tumor vasculature to radiotherapy and c-Met inhibitors. Angiogenesis. 2021 08; 24(3):597-611. PMID: 33629198.
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    66. Li J, Galbo PM, Gong W, Storey AJ, Tsai YH, Yu X, Ahn JH, Guo Y, Mackintosh SG, Edmondson RD, Byrum SD, Farrar JE, He S, Cai L, Jin J, Tackett AJ, Zheng D, Wang GG. ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism. Nat Commun. 2021 02 16; 12(1):1045. PMID: 33594072.
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    67. Garcia M, Salazar R, Wilson T, Lucas S, Herbert G, Young T, Begay J, Denson JL, Zychowski K, Ashley R, Byrum S, Mackintosh S, Bleske BE, Ottens AK, Campen MJ. Early Gestational Exposure to Inhaled Ozone Impairs Maternal Uterine Artery and Cardiac Function. Toxicol Sci. 2021 01 06; 179(1):121-134. PMID: 33146391.
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    68. Martinez Barrera S, Byrum S, Mackintosh SG, Kozubowski L. Registered report protocol: Quantitative analysis of septin Cdc10-associated proteome in Cryptococcus neoformans. PLoS One. 2020; 15(12):e0242381. PMID: 33315917.
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    69. Hong A, Piva M, Liu S, Hugo W, Lomeli SH, Zoete V, Randolph CE, Yang Z, Wang Y, Lee JJ, Lo SJ, Sun L, Vega-Crespo A, Garcia AJ, Shackelford DB, Dubinett SM, Scumpia PO, Byrum SD, Tackett AJ, Donahue TR, Michielin O, Holmen SL, Ribas A, Moriceau G, Lo RS. Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity. Cancer Discov. 2021 03; 11(3):714-735. PMID: 33318037.
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    70. Ramirez AM, Beenken KE, Byrum SD, Tackett AJ, Shaw LN, Gimza BD, Smeltzer MS. SarA plays a predominant role in controlling the production of extracellular proteases in the diverse clinical isolates of Staphylococcus aureus LAC and UAMS-1. Virulence. 2020 12; 11(1):1738-1762. PMID: 33258416.
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    71. Xu YZ, Jenjaroenpun P, Wongsurawat T, Byrum SD, Shponka V, Tannahill D, Chavez EA, Hung SS, Steidl C, Balasubramanian S, Rimsza LM, Kendrick S. Activation-induced cytidine deaminase localizes to G-quadruplex motifs at mutation hotspots in lymphoma. NAR Cancer. 2020 Dec; 2(4):zcaa029. PMID: 33094287.
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    72. Koss B, Shields BD, Taylor EM, Storey AJ, Byrum SD, Gies AJ, Washam CL, Choudhury SR, Hyun Ahn J, Uryu H, Williams JB, Krager KJ, Chiang TC, Mackintosh SG, Edmondson RD, Aykin-Burns N, Gajewski TF, Wang GG, Tackett AJ. Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion. Cancer Res. 2020 11 01; 80(21):4707-4719. PMID: 33004350.
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    73. Graw S, Tang J, Zafar MK, Byrd AK, Bolden C, Peterson EC, Byrum SD. proteiNorm - A User-Friendly Tool for Normalization and Analysis of TMT and Label-Free Protein Quantification. ACS Omega. 2020 Oct 13; 5(40):25625-25633. PMID: 33073088.
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    74. Mao XW, Nishiyama NC, Byrum SD, Stanbouly S, Jones T, Holley J, Sridharan V, Boerma M, Tackett AJ, Willey JS, Pecaut MJ, Delp MD. Spaceflight induces oxidative damage to blood-brain barrier integrity in a mouse model. FASEB J. 2020 11; 34(11):15516-15530. PMID: 32981077.
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    75. Batteiger TA, Spencer N, Washam CL, Byrum S, Eledge M, Batteiger BE, Rank RG, Yeruva L. Endocervical miRNA Expression Profiles in Women Positive for Chlamydia trachomatis with Clinical Signs and/or Symptoms Are Distinct from Those in Women Positive for Chlamydia trachomatis without Signs and Symptoms. Infect Immun. 2020 09 18; 88(10). PMID: 32690634.
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    76. Taylor EM, Byrum SD, Edmondson JL, Wardell CP, Griffin BG, Shalin SC, Gokden M, Makhoul I, Tackett AJ, Rodriguez A. Proteogenomic analysis of melanoma brain metastases from distinct anatomical sites identifies pathways of metastatic progression. Acta Neuropathol Commun. 2020 09 05; 8(1):157. PMID: 32891176.
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    77. Newton J, Brown T, Corley C, Alexander T, Trujillo M, McElroy T, Ntagwabira F, Wang J, Byrum SD, Allen AR. Cranial irradiation impairs juvenile social memory and modulates hippocampal physiology. Brain Res. 2020 12 01; 1748:147095. PMID: 32896524.
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    78. Elolimy AA, Washam C, Byrum S, Chen C, Dawson H, Bowlin AK, Randolph CE, Saraf MK, Yeruva L. Formula Diet Alters the Ileal Metagenome and Transcriptome at Weaning and during the Postweaning Period in a Porcine Model. mSystems. 2020 Aug 04; 5(4). PMID: 32753508.
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    79. Carr LE, Bowlin AK, Elolimy AA, Byrum SD, Washam CL, Randolph CE, MacLeod SL, Yeruva L. Neonatal Diet Impacts Circulatory miRNA Profile in a Porcine Model. Front Immunol. 2020; 11:1240. PMID: 32655560.
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    80. Storey AJ, Naceanceno KS, Lan RS, Washam CL, Orr LM, Mackintosh SG, Tackett AJ, Edmondson RD, Wang Z, Li HY, Frett B, Kendrick S, Byrum SD. ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data. Mol Omics. 2020 08 01; 16(4):316-326. PMID: 32347222.
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    81. McElroy T, Brown T, Kiffer F, Wang J, Byrum SD, Oberley-Deegan RE, Allen AR. Assessing the Effects of Redox Modifier MnTnBuOE-2-PyP 5+ on Cognition and Hippocampal Physiology Following Doxorubicin, Cyclophosphamide, and Paclitaxel Treatment. Int J Mol Sci. 2020 Mar 09; 21(5). PMID: 32182883.
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    82. Storey AJ, Hardman RE, Byrum SD, Mackintosh SG, Edmondson RD, Wahls WP, Tackett AJ, Lewis JA. Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags. J Proteome Res. 2020 03 06; 19(3):1183-1195. PMID: 32027144.
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    83. Dimori M, Heard-Lipsmeyer ME, Byrum SD, Mackintosh SG, Kurten RC, Carroll JL, Morello R. Respiratory defects in the CrtapKO mouse model of osteogenesis imperfecta. Am J Physiol Lung Cell Mol Physiol. 2020 04 01; 318(4):L592-L605. PMID: 32022592.
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    84. Ramirez AM, Byrum SD, Beenken KE, Washam C, Edmondson RD, Mackintosh SG, Spencer HJ, Tackett AJ, Smeltzer MS. Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis. ACS Infect Dis. 2020 02 14; 6(2):237-249. PMID: 31722523.
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    85. Byrum SD, Washam CL, Tackett AJ, Garcia-Rill E, Bisagno V, Urbano FJ. Proteomic measures of gamma oscillations. Heliyon. 2019 Aug; 5(8):e02265. PMID: 31497668.
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    86. Byrum SD, Washam CL, Patterson JD, Vyas KK, Gilbert KM, Blossom SJ. Continuous Developmental and Early Life Trichloroethylene Exposure Promoted DNA Methylation Alterations in Polycomb Protein Binding Sites in Effector/Memory CD4+ T Cells. Front Immunol. 2019; 10:2016. PMID: 31555266.
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    87. Shelby M, Malloch K, Shellenberger T, Byrum S, Mackie L, Dilli S, Dean Martin A. Addressing Falls Among Older Oncology Patients Through Complexity Science. Nurs Adm Q. 2019 Jul/Sep; 43(3):280-288. PMID: 31162348.
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    88. Chiang TC, Koss B, Su LJ, Washam CL, Byrum SD, Storey A, Tackett AJ. Effect of Sulforaphane and 5-Aza-2'-Deoxycytidine on Melanoma Cell Growth. Medicines (Basel). 2019 Jun 27; 6(3). PMID: 31252639.
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    89. Mao XW, Nishiyama NC, Byrum SD, Stanbouly S, Jones T, Drew A, Sridharan V, Boerma M, Tackett AJ, Zawieja D, Willey JS, Delp M, Pecaut MJ. Characterization of mouse ocular response to a 35-day spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations. Sci Rep. 2019 06 03; 9(1):8215. PMID: 31160660.
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    90. Cragle CE, MacNicol MC, Byrum SD, Hardy LL, Mackintosh SG, Richardson WA, Gray NK, Childs GV, Tackett AJ, MacNicol AM. Musashi interaction with poly(A)-binding protein is required for activation of target mRNA translation. J Biol Chem. 2019 07 12; 294(28):10969-10986. PMID: 31152063.
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    91. Lo S, Byrum SD, Tackett AJ, Parajuli N. Cold Storage Increases Albumin and Advanced Glycation-End Product-Albumin Levels in Kidney Transplants: A Possible Cause for Exacerbated Renal Damage. Transplant Direct. 2019 Jun; 5(6):e454. PMID: 31723591.
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    92. Garcia-Rill E, Tackett AJ, Byrum SD, Lan RS, Mackintosh SG, Hyde JR, Bisagno V, Urbano FJ. Local and Relayed Effects of Deep Brain Stimulation of the Pedunculopontine Nucleus. Brain Sci. 2019 Mar 18; 9(3). PMID: 30889866.
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    93. West KL, Byrum SD, Mackintosh SG, Edmondson RD, Taverna SD, Tackett AJ. Proteomic characterization of the arsenic response locus in S. cerevisiae. Epigenetics. 2019 02; 14(2):130-145. PMID: 30739529.
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    94. Zybailov BL, Glazko GV, Rahmatallah Y, Andreyev DS, McElroy T, Karaduta O, Byrum SD, Orr L, Tackett AJ, Mackintosh SG, Edmondson RD, Kieffer DA, Martin RJ, Adams SH, Vaziri ND, Arthur JM. Metaproteomics reveals potential mechanisms by which dietary resistant starch supplementation attenuates chronic kidney disease progression in rats. PLoS One. 2019; 14(1):e0199274. PMID: 30699108.
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    95. Shields BD, Koss B, Taylor EM, Storey AJ, West KL, Byrum SD, Mackintosh SG, Edmondson R, Mahmoud F, Shalin SC, Tackett AJ. Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma. Cancer Res. 2019 03 15; 79(6):1113-1123. PMID: 30674537.
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    96. Byrum SD, Loughran AJ, Beenken KE, Orr LM, Storey AJ, Mackintosh SG, Edmondson RD, Tackett AJ, Smeltzer MS. Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome. J Proteome Res. 2018 10 05; 17(10):3384-3395. PMID: 30209945.
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    97. Barham C, Fil D, Byrum SD, Rahmatallah Y, Glazko G, Kiaei M. RNA-Seq Analysis of Spinal Cord Tissues from hPFN1G118V Transgenic Mouse Model of ALS at Pre-symptomatic and End-Stages of Disease. Sci Rep. 2018 09 13; 8(1):13737. PMID: 30213953.
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    98. Mao XW, Byrum S, Nishiyama NC, Pecaut MJ, Sridharan V, Boerma M, Tackett AJ, Shiba D, Shirakawa M, Takahashi S, Delp MD. Impact of Spaceflight and Artificial Gravity on the Mouse Retina: Biochemical and Proteomic Analysis. Int J Mol Sci. 2018 Aug 28; 19(9). PMID: 30154332.
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    99. Cheema AK, Byrum SD, Sharma NK, Altadill T, Kumar VP, Biswas S, Balgley BM, Hauer-Jensen M, Tackett AJ, Ghosh SP. Proteomic Changes in Mouse Spleen after Radiation-Induced Injury and its Modulation by Gamma-Tocotrienol. Radiat Res. 2018 11; 190(5):449-463. PMID: 30070965.
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    100. Holthoff ER, Byrum SD, Mackintosh SG, Kelly T, Tackett AJ, Quick CM, Post SR. Vulvar squamous cell carcinoma aggressiveness is associated with differential expression of collagen and STAT1. Clin Proteomics. 2017; 14:40. PMID: 29225558.
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    101. Wang P, Byrum S, Fowler FC, Pal S, Tackett AJ, Tyler JK. Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break. Nucleic Acids Res. 2017 Nov 02; 45(19):10923-10940. PMID: 29036368.
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    102. Shields BD, Mahmoud F, Taylor EM, Byrum SD, Sengupta D, Koss B, Baldini G, Ransom S, Cline K, Mackintosh SG, Edmondson RD, Shalin S, Tackett AJ. Indicators of responsiveness to immune checkpoint inhibitors. Sci Rep. 2017 04 11; 7(1):807. PMID: 28400597.
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    103. Byrum SD, Burdine MS, Orr L, Mackintosh SG, Authier S, Pouliot M, Hauer-Jensen M, Tackett AJ. Time- and radiation-dose dependent changes in the plasma proteome after total body irradiation of non-human primates: Implications for biomarker selection. PLoS One. 2017; 12(3):e0174771. PMID: 28350824.
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    104. Hartman JH, Miller GP, Caro AA, Byrum SD, Orr LM, Mackintosh SG, Tackett AJ, MacMillan-Crow LA, Hallberg LM, Ameredes BT, Boysen G. 1,3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice. Toxicology. 2017 03 01; 378:114-124. PMID: 28082109.
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    105. Loughran AJ, Gaddy D, Beenken KE, Meeker DG, Morello R, Zhao H, Byrum SD, Tackett AJ, Cassat JE, Smeltzer MS. Impact of sarA and Phenol-Soluble Modulins on the Pathogenesis of Osteomyelitis in Diverse Clinical Isolates of Staphylococcus aureus. Infect Immun. 2016 09; 84(9):2586-94. PMID: 27354444.
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    106. Atanassov BS, Mohan RD, Lan X, Kuang X, Lu Y, Lin K, McIvor E, Li W, Zhang Y, Florens L, Byrum SD, Mackintosh SG, Calhoun-Davis T, Koutelou E, Wang L, Tang DG, Tackett AJ, Washburn MP, Workman JL, Dent SY. ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth. Mol Cell. 2016 05 19; 62(4):558-71. PMID: 27132940.
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    107. Wu TP, Wang T, Seetin MG, Lai Y, Zhu S, Lin K, Liu Y, Byrum SD, Mackintosh SG, Zhong M, Tackett A, Wang G, Hon LS, Fang G, Swenberg JA, Xiao AZ. DNA methylation on N(6)-adenine in mammalian embryonic stem cells. Nature. 2016 Apr 21; 532(7599):329-33. PMID: 27027282.
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    108. Byrum SD, Burdine MS, Orr L, Moreland L, Mackintosh SG, Authier S, Pouliot M, Hauer-Jensen M, Tackett AJ. A Quantitative Proteomic Analysis of Urine from Gamma-Irradiated Non-Human Primates. J Proteomics Bioinform. 2016; 9(Suppl 10). PMID: 26962295.
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    109. Sengupta D, Byrum SD, Avaritt NL, Davis L, Shields B, Mahmoud F, Reynolds M, Orr LM, Mackintosh SG, Shalin SC, Tackett AJ. Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma. Mol Cell Proteomics. 2016 Mar; 15(3):765-75. PMID: 26621846.
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    110. Salinas E, Byrum SD, Moreland LE, Mackintosh SG, Tackett AJ, Forrest JC. Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication. J Virol. 2016 02 01; 90(3):1397-413. PMID: 26581985.
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    111. Byrum SD, Taverna SD, Tackett AJ. Purification of specific chromatin loci for proteomic analysis. Methods Mol Biol. 2015; 1228:83-92. PMID: 25311124.
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    112. Gilbert TM, McDaniel SL, Byrum SD, Cades JA, Dancy BC, Wade H, Tackett AJ, Strahl BD, Taverna SD. A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions. Mol Cell Proteomics. 2014 Nov; 13(11):2883-95. PMID: 25104842.
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    113. Waldrip ZJ, Byrum SD, Storey AJ, Gao J, Byrd AK, Mackintosh SG, Wahls WP, Taverna SD, Raney KD, Tackett AJ. A CRISPR-based approach for proteomic analysis of a single genomic locus. Epigenetics. 2014 Sep; 9(9):1207-11. PMID: 25147920.
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    114. Udensi UK, Tackett AJ, Byrum S, Avaritt NL, Sengupta D, Moreland LW, Tchounwou PB, Isokpehi RD. Proteomics-Based Identification of Differentially Abundant Proteins from Human Keratinocytes Exposed to Arsenic Trioxide. J Proteomics Bioinform. 2014 Jul; 7(7):166-178. PMID: 25419056.
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    115. Zhu B, Zhang M, Byrum SD, Tackett AJ, Davie JK. TBX2 blocks myogenesis and promotes proliferation in rhabdomyosarcoma cells. Int J Cancer. 2014 Aug 15; 135(4):785-97. PMID: 24470334.
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    116. Shao Q, Byrum SD, Moreland LE, Mackintosh SG, Kannan A, Lin Z, Morgan M, Stack BC, Cornelius LA, Tackett AJ, Gao L. A Proteomic Study of Human Merkel Cell Carcinoma. J Proteomics Bioinform. 2013 Nov 25; 6:275-282. PMID: 25284964.
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    117. Hammond SL, Byrum SD, Namjoshi S, Graves HK, Dennehey BK, Tackett AJ, Tyler JK. Mitotic phosphorylation of histone H3 threonine 80. Cell Cycle. 2014; 13(3):440-52. PMID: 24275038.
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    118. Byrum SD, Taverna SD, Tackett AJ. Purification of a specific native genomic locus for proteomic analysis. Nucleic Acids Res. 2013 Nov; 41(20):e195. PMID: 24030711.
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    119. Mercado CP, Byrum S, Beggs ML, Ziu E, Singh P, Raj VR, Haun RS, Kilic F. Impact of elevated plasma serotonin on global gene expression of murine megakaryocytes. PLoS One. 2013; 8(8):e72580. PMID: 24013211.
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    120. Washam CL, Byrum SD, Leitzel K, Ali SM, Tackett AJ, Gaddy D, Sundermann SE, Lipton A, Suva LJ. Identification of PTHrP(12-48) as a plasma biomarker associated with breast cancer bone metastasis. Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):972-83. PMID: 23462923.
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    121. Byrum SD, Larson SK, Avaritt NL, Moreland LE, Mackintosh SG, Cheung WL, Tackett AJ. Quantitative Proteomics Identifies Activation of Hallmark Pathways of Cancer in Patient Melanoma. J Proteomics Bioinform. 2013 Mar 01; 6(3):43-50. PMID: 23976835.
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    122. Lolis AA, Londhe P, Beggs BC, Byrum SD, Tackett AJ, Davie JK. Myogenin recruits the histone chaperone facilitates chromatin transcription (FACT) to promote nucleosome disassembly at muscle-specific genes. J Biol Chem. 2013 Mar 15; 288(11):7676-7687. PMID: 23364797.
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    123. Byrum SD, Raman A, Taverna SD, Tackett AJ. ChAP-MS: a method for identification of proteins and histone posttranslational modifications at a single genomic locus. Cell Rep. 2012 Jul 26; 2(1):198-205. PMID: 22840409.
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    124. Avaritt NL, Owens R, Larson SK, Reynolds M, Byrum S, Hiatt KM, Smoller BR, Tackett AJ, Cheung WL. Misregulation of Rad50 expression in melanoma cells. J Cutan Pathol. 2012 Jul; 39(7):680-684. PMID: 22725639.
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    125. Byrum SD, Washam CL, Montgomery CO, Tackett AJ, Suva LJ. Proteomic technologies for the study of osteosarcoma. Sarcoma. 2012; 2012:169416. PMID: 22550414.
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    126. Stephanie Byrum, Sherri K. Smart, Signe Larson, Alan J. Tackett. Chromatin Remodeling Methods in Molecular Biology. Analysis of Stable and Transient Protein-Protein Interactions. 2012; 833.
    127. Byrum S, Smart SK, Larson S, Tackett AJ. Analysis of stable and transient protein-protein interactions. Methods Mol Biol. 2012; 833:143-52. PMID: 22183593.
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    128. Byrum S, Avaritt NL, Mackintosh SG, Munkberg JM, Badgwell BD, Cheung WL, Tackett AJ. A quantitative proteomic analysis of FFPE melanoma. J Cutan Pathol. 2011 Nov; 38(11):933-6. PMID: 21883366.
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    129. Byrum SD, Taverna SD, Tackett AJ. Quantitative analysis of histone exchange for transcriptionally active chromatin. J Clin Bioinforma. 2011 Jul 07; 1(1):17. PMID: 21884633.
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    130. Stephanie Byrum, Samuel G. Mackintosh, Ricky D. Edmondson, Wang L Cheung, Sean D. Taverna, Alan J. Tackett. Analysis of Histone Exchange During Chromatin Purification. J Integr OMICS. 2011; 1(1):61-65.
    131. Byrum S, Mackintosh SG, Edmondson RD, Cheung WL, Taverna SD, Tackett AJ. Analysis of Histone Exchange during Chromatin Purification. J Integr OMICS. 2011 Feb 01; 1(1):61-65. PMID: 21709819.
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    132. Byrum S, Montgomery CO, Nicholas RW, Suva LJ. The promise of bone cancer proteomics. Ann N Y Acad Sci. 2010 Mar; 1192:222-9. PMID: 20392240.
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    133. Gradolatto A, Smart SK, Byrum S, Blair LP, Rogers RS, Kolar EA, Lavender H, Larson SK, Aitchison JD, Taverna SD, Tackett AJ. A noncanonical bromodomain in the AAA ATPase protein Yta7 directs chromosomal positioning and barrier chromatin activity. Mol Cell Biol. 2009 Sep; 29(17):4604-11. PMID: 19581291.
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    134. Stephanie Byrum, Eric R. Siegel, Sudeepa Bhattacharyya, Larry J. Suva. Bone Cancer: Progression and Therapeutic Approaches. Proteomics of Bone Cancers. 2009; 14.
    135. Bhattacharyya S, Byrum S, Siegel ER, Suva LJ. Proteomic analysis of bone cancer: a review of current and future developments. Expert Rev Proteomics. 2007 Jun; 4(3):371-8. PMID: 17552921.
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