Clostridium difficile
"Clostridium difficile" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.
Descriptor ID |
D016360
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MeSH Number(s) |
B03.300.390.400.200.250 B03.510.415.400.200.250
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Clostridium difficile".
Below are MeSH descriptors whose meaning is more specific than "Clostridium difficile".
This graph shows the total number of publications written about "Clostridium difficile" by people in UAMS Profiles by year, and whether "Clostridium difficile" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2019 | 2 | 0 | 2 | 2018 | 1 | 1 | 2 | 2017 | 2 | 4 | 6 | 2016 | 0 | 2 | 2 | 2015 | 4 | 0 | 4 | 2014 | 1 | 0 | 1 | 2013 | 6 | 0 | 6 | 2012 | 1 | 1 | 2 | 2011 | 4 | 0 | 4 | 2009 | 1 | 0 | 1 | 2005 | 2 | 0 | 2 |
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Below are the most recent publications written about "Clostridium difficile" by people in Profiles over the past ten years.
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Juretschko S, Manji R, Khare R, Das S, Dunbar S. Performance Evaluation of the Luminex Aries C. difficile Assay in Comparison to Two Other Molecular Assays within a Multihospital Health Care Center. J Clin Microbiol. 2019 11; 57(11).
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Berry ASF, Kelly BJ, Barnhart D, Kelly DJ, Beiting DP, Baldassano RN, Redding LE. Gut microbiota features associated with Clostridioides difficile colonization in puppies. PLoS One. 2019; 14(8):e0215497.
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Syal G, Kashani A, Shih DQ. Fecal Microbiota Transplantation in Inflammatory Bowel Disease: A Primer for Internists. Am J Med. 2018 09; 131(9):1017-1024.
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Cabal A, Jun SR, Jenjaroenpun P, Wanchai V, Nookaew I, Wongsurawat T, Burgess MJ, Kothari A, Wassenaar TM, Ussery DW. Genome-Based Comparison of Clostridioides difficile: Average Amino Acid Identity Analysis of Core Genomes. Microb Ecol. 2018 Oct; 76(3):801-813.
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Chatterjee K, Goyal A, Chada A, Kakkera KS, Corwin HL. National Trends (2007-2013) of Clostridium difficile Infection in Patients with Septic Shock: Impact on Outcome. J Hosp Med. 2017 09; 12(9):717-722.
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Goyal A, Chatterjee K, Yadlapati S, Rangaswami J. Impact of end stage kidney disease on costs and outcomes of Clostridium difficile infection. Int J Infect Dis. 2017 Sep; 62:8-9.
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Goyal A, Chatterjee K, Punjabi C, Rangaswami J. Thirty-Day Readmissions After Hospitalization for Clostridium difficile Enteritis Measures and Predictors: A Nationwide Analysis. Infect Control Hosp Epidemiol. 2017 07; 38(7):876-878.
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Shah NN, McClellan W, Flowers CR, Lonial S, Khoury H, Waller EK, Langston A, Nooka AK. Evaluating Risk Factors for Clostridium difficile Infection In Stem Cell Transplant Recipients: A National Study. Infect Control Hosp Epidemiol. 2017 06; 38(6):651-657.
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Anand R, Song Y, Garg S, Girotra M, Sinha A, Sivaraman A, Phillips L, Dutta SK. Effect of Aging on the Composition of Fecal Microbiota in Donors for FMT and Its Impact on Clinical Outcomes. Dig Dis Sci. 2017 04; 62(4):1002-1008.
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Njoku JC, Van Schooneveld TC, Rupp ME, Olsen KM, Qiu F, Meza JL, Hermsen ED. Lack of Benefit With Combination Therapy for Clostridium difficile Infection. Infect Control Hosp Epidemiol. 2017 05; 38(5):602-605.
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Girotra M, Garg S, Anand R, Song Y, Dutta SK. Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection in the Elderly: Long-Term Outcomes and Microbiota Changes. Dig Dis Sci. 2016 10; 61(10):3007-3015.
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McCaleb RV, Gandhi AS, Clark SM, Clemmons AB. Clinical Outcomes of Acid Suppressive Therapy Use in Hematology/Oncology Patients at an Academic Medical Center. Ann Pharmacother. 2016 07; 50(7):541-7.
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Costello SP, Tucker EC, La Brooy J, Schoeman MN, Andrews JM. Establishing a Fecal Microbiota Transplant Service for the Treatment of Clostridium difficile Infection. Clin Infect Dis. 2016 Apr 01; 62(7):908-14.
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Bharti S, Malhotra P, Juretschko S. Successful Treatment of Peritoneal Dialysis Catheter-Related Polymicrobial Peritonitis Involving Clostridium difficile. J Clin Microbiol. 2015 Dec; 53(12):3945-6.
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Blount KF, Megyola C, Plummer M, Osterman D, O'Connell T, Aristoff P, Quinn C, Chrusciel RA, Poel TJ, Schostarez HJ, Stewart CA, Walker DP, Wuts PG, Breaker RR. Novel riboswitch-binding flavin analog that protects mice against Clostridium difficile infection without inhibiting cecal flora. Antimicrob Agents Chemother. 2015 Sep; 59(9):5736-46.
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Apewokin S, Goodwin JA, Lee JY, Erickson SW, Sanathkumar N, Raj VR, Zhou D, McKelvey KD, Stephens O, Coleman EA. Contribution of Clostridium difficile infection to the development of lower gastrointestinal adverse events during autologous stem cell transplantation. Transpl Infect Dis. 2015 Aug; 17(4):566-73.
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Walia R, Garg S, Song Y, Girotra M, Cuffari C, Fricke WF, Dutta SK. Efficacy of fecal microbiota transplantation in 2 children with recurrent Clostridium difficile infection and its impact on their growth and gut microbiome. J Pediatr Gastroenterol Nutr. 2014 Nov; 59(5):565-70.
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Apewokin S, Wontumi GM, Kumar NS, Matin A, Grazziutti M. Severe mucositis and Clostridium difficile infection in adult autologous stem cell recipients: another question of the chicken or the egg? Biol Blood Marrow Transplant. 2014 Feb; 20(2):288.
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Song Y, Garg S, Girotra M, Maddox C, von Rosenvinge EC, Dutta A, Dutta S, Fricke WF. Microbiota dynamics in patients treated with fecal microbiota transplantation for recurrent Clostridium difficile infection. PLoS One. 2013; 8(11):e81330.
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Garg S, Mirza YR, Girotra M, Kumar V, Yoselevitz S, Segon A, Dutta SK. Epidemiology of Clostridium difficile-associated disease (CDAD): a shift from hospital-acquired infection to long-term care facility-based infection. Dig Dis Sci. 2013 Dec; 58(12):3407-12.
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Girotra M, Abraham RR, Pahwa M. Clostridium difficile infection: how safe are the household contacts? Am J Infect Control. 2013 Nov; 41(11):1140-1.
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Com G, Cetin N, O'Brien CE. Complicated Clostridium difficile colitis in children with cystic fibrosis: association with gastric acid suppression? J Cyst Fibros. 2014 Jan; 13(1):37-42.
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Krishna SG, Zhao W, Apewokin SK, Krishna K, Chepyala P, Anaissie EJ. Risk factors, preemptive therapy, and antiperistaltic agents for Clostridium difficile infection in cancer patients. Transpl Infect Dis. 2013 Oct; 15(5):493-501.
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Mavros MN, Alexiou VG, Vardakas KZ, Tsokali K, Sardi TA, Falagas ME. Underestimation of Clostridium difficile infection among clinicians: an international survey. Eur J Clin Microbiol Infect Dis. 2012 Sep; 31(9):2439-44.
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Girotra M, Kumar V, Khan JM, Damisse P, Abraham RR, Aggarwal V, Dutta SK. Clinical predictors of fulminant colitis in patients with Clostridium difficile infection. Saudi J Gastroenterol. 2012 Mar-Apr; 18(2):133-9.
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Boyanton BL, Sural P, Loomis CR, Pesta C, Gonzalez-Krellwitz L, Robinson-Dunn B, Riska P. Loop-mediated isothermal amplification compared to real-time PCR and enzyme immunoassay for toxigenic Clostridium difficile detection. J Clin Microbiol. 2012 Mar; 50(3):640-5.
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Hirshon JM, Thompson AD, Limbago B, McDonald LC, Bonkosky M, Heimer R, Meek J, Mai V, Braden C. Clostridium difficile infection in outpatients, Maryland and Connecticut, USA, 2002-2007. Emerg Infect Dis. 2011 Oct; 17(10):1946-9.
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