 Leukemia
"Leukemia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Descriptor ID |
D007938
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| MeSH Number(s) |
C04.557.337
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| Concept/Terms |
Leukemia- Leukemia
- Leukemias
- Leucocythaemia
- Leucocythaemias
- Leucocythemia
- Leucocythemias
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Below are MeSH descriptors whose meaning is more general than "Leukemia".
Below are MeSH descriptors whose meaning is more specific than "Leukemia".
This graph shows the total number of publications written about "Leukemia" by people in UAMS Profiles by year, and whether "Leukemia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 4 | 0 | 4 | | 2020 | 2 | 0 | 2 | | 2019 | 1 | 1 | 2 | | 2017 | 1 | 0 | 1 | | 2016 | 2 | 1 | 3 | | 2015 | 1 | 1 | 2 | | 2014 | 2 | 0 | 2 | | 2013 | 4 | 0 | 4 | | 2012 | 0 | 1 | 1 | | 2011 | 2 | 0 | 2 | | 2008 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2005 | 4 | 0 | 4 | | 2004 | 0 | 2 | 2 | | 2003 | 2 | 1 | 3 | | 2002 | 2 | 1 | 3 | | 2001 | 3 | 0 | 3 | | 1999 | 0 | 1 | 1 | | 1998 | 2 | 2 | 4 | | 1996 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 1994 | 3 | 0 | 3 | | 1993 | 2 | 1 | 3 | | 1989 | 0 | 2 | 2 | | 1988 | 2 | 0 | 2 | | 1987 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukemia" by people in Profiles over the past ten years.
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Thakur S, Jain M, Zhang C, Major C, Bielamowicz KJ, Lacayo NJ, Vaske O, Lewis V, Murguia-Favela L, Narendran A. Identification and in vitro validation of neoantigens for immune activation against high-risk pediatric leukemia cells. Hum Vaccin Immunother. 2021 12 02; 17(12):5558-5562.
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Lv D, Pal P, Liu X, Jia Y, Thummuri D, Zhang P, Hu W, Pei J, Zhang Q, Zhou S, Khan S, Zhang X, Hua N, Yang Q, Arango S, Zhang W, Nayak D, Olsen SK, Weintraub ST, Hromas R, Konopleva M, Yuan Y, Zheng G, Zhou D. Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity. Nat Commun. 2021 11 25; 12(1):6896.
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Pukhalskaya T, Smoller B. Perineural invasion and neural prominence in leukemia cutis. Eur J Dermatol. 2021 Oct 01; 31(5):645-646.
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Amaza I, Kalra H, Eberlein M, Jethava Y, McDonell J, Wolfe B, Tomasson MH, Bates ML. Case Studies in Physiology: Untangling the cause of hypoxemia in a patient with obesity with acute leukemia. J Appl Physiol (1985). 2021 08 01; 131(2):788-793.
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Vara N, Liu Y, Yan Y, Lensing SY, Colorado N, Robinson D, Zhang J, Zhang X, Peterson EA, Baltz NJ, Zhou D, Bertaina A, Johann DJ, Emanuel PD, Liu YL. Sustained fetal hematopoiesis causes juvenile death from leukemia: evidence from a dual-age-specific mouse model. Blood Adv. 2020 08 11; 4(15):3728-3740.
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He Y, Khan S, Huo Z, Lv D, Zhang X, Liu X, Yuan Y, Hromas R, Xu M, Zheng G, Zhou D. Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies. J Hematol Oncol. 2020 07 27; 13(1):103.
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Boysen G, Shimoni A, Danylesko I, Varda-Bloom N, Nagler A. A simplified method for detection of N-terminal valine adducts in patients receiving treosulfan. Rapid Commun Mass Spectrom. 2019 Nov 15; 33(21):1635-1642.
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Utuama O, Mukhtar F, Pham YT, Dabo B, Manani P, Moser J, Michael-Asalu A, Tran CT, Le LC, Le TV, Vu KT, Park JY, Boffetta P, Zheng W, Shu XO, Luu HN. Racial/ethnic, age and sex disparities in leukemia survival among adults in the United States during 1973-2014 period. PLoS One. 2019; 14(8):e0220864.
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Johnsrud AJ, Pina-Oviedo S. Carcinocythemia (carcinoma cell leukemia). Blood. 2017 11 23; 130(21):2357.
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Guru Murthy GS, Dhakal I, Lee JY, Mehta P. Acute Leukemia of Ambiguous Lineage in Elderly Patients - Analysis of Survival Using Surveillance Epidemiology and End Results-Medicare Database. Clin Lymphoma Myeloma Leuk. 2017 02; 17(2):100-107.
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Wren D, Walker BA, Brüggemann M, Catherwood MA, Pott C, Stamatopoulos K, Langerak AW, Gonzalez D. Comprehensive translocation and clonality detection in lymphoproliferative disorders by next-generation sequencing. Haematologica. 2017 02; 102(2):e57-e60.
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Paugh SW, Coss DR, Bao J, Laudermilk LT, Grace CR, Ferreira AM, Waddell MB, Ridout G, Naeve D, Leuze M, LoCascio PF, Panetta JC, Wilkinson MR, Pui CH, Naeve CW, Uberbacher EC, Bonten EJ, Evans WE. MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression. PLoS Comput Biol. 2016 Feb; 12(2):e1004744.
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Wilke C, Holtan SG, Sharkey L, DeFor T, Arora M, Premakanthan P, Yohe S, Vagge S, Zhou D, Holter Chakrabarty JL, Mahe M, Corvo R, Dusenbery K, Storme G, Weisdorf DJ, Verneris MR, Hui S. Marrow damage and hematopoietic recovery following allogeneic bone marrow transplantation for acute leukemias: Effect of radiation dose and conditioning regimen. Radiother Oncol. 2016 Jan; 118(1):65-71.
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Philchenkov AA, Zavelevich MP, Tryndyak VP, Kuiava LM, Blokhin DY, Miura K, Silvestri R, Pogribny IP. Antiproliferative and proapoptotic effects of a pyrrole containing arylthioindole in human Jurkat leukemia cell line and multidrug-resistant Jurkat/A4 cells. Cancer Biol Ther. 2015; 16(12):1820-9.
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You Y, Wen R, Pathak R, Li A, Li W, St Clair D, Hauer-Jensen M, Zhou D, Liang Y. Latexin sensitizes leukemogenic cells to gamma-irradiation-induced cell-cycle arrest and cell death through Rps3 pathway. Cell Death Dis. 2014 Oct 23; 5:e1493.
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Nucci M, Anaissie E. How we treat invasive fungal diseases in patients with acute leukemia: the importance of an individualized approach. Blood. 2014 Dec 18; 124(26):3858-69.
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Eichhorn JM, Alford SE, Hughes CC, Fenical W, Chambers TC. Purported Mcl-1 inhibitor marinopyrrole A fails to show selective cytotoxicity for Mcl-1-dependent cell lines. Cell Death Dis. 2013 Oct 24; 4:e880.
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Tao Y, Gao L, Wu X, Wang H, Yang G, Zhan F, Shi J. Down-regulation of 11ß-hydroxysteroid dehydrogenase type 2 by bortezomib sensitizes Jurkat leukemia T cells against glucocorticoid-induced apoptosis. PLoS One. 2013; 8(6):e67067.
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Usmani SZ, Sawyer J, Rosenthal A, Cottler-Fox M, Epstein J, Yaccoby S, Sexton R, Hoering A, Singh Z, Heuck CJ, Waheed S, Chauhan N, Johann D, Abdallah AO, Muzaffar J, Petty N, Bailey C, Crowley J, van Rhee F, Barlogie B. Risk factors for MDS and acute leukemia following total therapy 2 and 3 for multiple myeloma. Blood. 2013 Jun 06; 121(23):4753-7.
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Wray J, Williamson EA, Singh SB, Wu Y, Cogle CR, Weinstock DM, Zhang Y, Lee SH, Zhou D, Shao L, Hauer-Jensen M, Pathak R, Klimek V, Nickoloff JA, Hromas R. PARP1 is required for chromosomal translocations. Blood. 2013 May 23; 121(21):4359-65.
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