Drug Delivery Systems
"Drug Delivery Systems" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.
Descriptor ID |
D016503
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MeSH Number(s) |
E02.319.300
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Concept/Terms |
Drug Delivery Systems- Drug Delivery Systems
- Delivery System, Drug
- Delivery Systems, Drug
- Drug Delivery System
- System, Drug Delivery
- Systems, Drug Delivery
- Drug Targeting
- Drug Targetings
- Targeting, Drug
- Targetings, Drug
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Below are MeSH descriptors whose meaning is more general than "Drug Delivery Systems".
Below are MeSH descriptors whose meaning is more specific than "Drug Delivery Systems".
This graph shows the total number of publications written about "Drug Delivery Systems" by people in UAMS Profiles by year, and whether "Drug Delivery Systems" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2022 | 0 | 3 | 3 | 2021 | 1 | 1 | 2 | 2020 | 1 | 5 | 6 | 2019 | 4 | 1 | 5 | 2018 | 2 | 1 | 3 | 2017 | 2 | 4 | 6 | 2016 | 4 | 1 | 5 | 2015 | 10 | 4 | 14 | 2014 | 6 | 4 | 10 | 2013 | 5 | 3 | 8 | 2012 | 2 | 2 | 4 | 2011 | 4 | 3 | 7 | 2010 | 3 | 2 | 5 | 2009 | 4 | 2 | 6 | 2008 | 4 | 3 | 7 | 2007 | 3 | 2 | 5 | 2006 | 2 | 2 | 4 | 2005 | 1 | 3 | 4 | 2004 | 1 | 1 | 2 | 2003 | 1 | 1 | 2 | 2002 | 1 | 3 | 4 | 2001 | 0 | 1 | 1 | 2000 | 0 | 1 | 1 | 1996 | 0 | 1 | 1 |
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Below are the most recent publications written about "Drug Delivery Systems" by people in Profiles over the past ten years.
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He T, Zhang C, Colombani T, Bencherif SA, Porter RM, Bajpayee AG. Intra-articular kinetics of a cartilage targeting cationic PEGylated protein for applications in drug delivery. Osteoarthritis Cartilage. 2023 Feb; 31(2):187-198.
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Ghosh S, Huda P, Fletcher NL, Howard CB, Walsh B, Campbell D, Pinkham MB, Thurecht KJ. Antibody-Based Formats to Target Glioblastoma: Overcoming Barriers to Protein Drug Delivery. Mol Pharm. 2022 05 02; 19(5):1233-1247.
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Macchi S, Jalihal A, Hooshmand N, Zubair M, Jenkins S, Alwan N, El-Sayed M, Ali N, Griffin RJ, Siraj N. Enhanced photothermal heating and combination therapy of NIR dye via conversion to self-assembled ionic nanomaterials. J Mater Chem B. 2022 02 02; 10(5):806-816.
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Qaqish R, Berlinski A. Effects of Shake-Actuation Delay on Delivered Dose and Aerosol Characteristics of an Albuterol Suspension From a Pressurized Metered-Dose Inhaler. Respir Care. 2021 Aug; 66(8):1315-1322.
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Beenken KE, Campbell MJ, Ramirez AM, Alghazali K, Walker CM, Jackson B, Griffin C, King W, Bourdo SE, Rifkin R, Hecht S, Meeker DG, Anderson DE, Biris AS, Smeltzer MS. Evaluation of a bone filler scaffold for local antibiotic delivery to prevent Staphylococcus aureus infection in a contaminated bone defect. Sci Rep. 2021 05 13; 11(1):10254.
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Amani H, Shahbazi MA, D'Amico C, Fontana F, Abbaszadeh S, Santos HA. Microneedles for painless transdermal immunotherapeutic applications. J Control Release. 2021 02 10; 330:185-217.
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Childress AC, Beltran N, Supnet C, Weiss MD. Reviewing the role of emerging therapies in the ADHD armamentarium. Expert Opin Emerg Drugs. 2021 03; 26(1):1-16.
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Grossman SA, Romo CG, Rudek MA, Supko J, Fisher J, Nabors LB, Wen PY, Peereboom DM, Ellingson BM, Elmquist W, Barker FG, Kamson D, Sarkaria JN, Timmer W, Bindra RS, Ye X. Baseline requirements for novel agents being considered for phase II/III brain cancer efficacy trials: conclusions from the Adult Brain Tumor Consortium's first workshop on CNS drug delivery. Neuro Oncol. 2020 10 14; 22(10):1422-1424.
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Sayed D, Chakravarthy K, Amirdelfan K, Kalia H, Meacham K, Shirvalkar P, Falowski S, Petersen E, Hagedorn JM, Pope J, Leever J, Deer T. A Comprehensive Practice Guideline for Magnetic Resonance Imaging Compatibility in Implanted Neuromodulation Devices. Neuromodulation. 2020 Oct; 23(7):893-911.
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Chakhalian D, Shultz RB, Miles CE, Kohn J. Opportunities for biomaterials to address the challenges of COVID-19. J Biomed Mater Res A. 2020 10; 108(10):1974-1990.
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Donovan LK, Delaidelli A, Joseph SK, Bielamowicz K, Fousek K, Holgado BL, Manno A, Srikanthan D, Gad AZ, Van Ommeren R, Przelicki D, Richman C, Ramaswamy V, Daniels C, Pallota JG, Douglas T, Joynt ACM, Haapasalo J, Nor C, Vladoiu MC, Kuzan-Fischer CM, Garzia L, Mack SC, Varadharajan S, Baker ML, Hendrikse L, Ly M, Kharas K, Balin P, Wu X, Qin L, Huang N, Stucklin AG, Morrissy AS, Cavalli FMG, Luu B, Suarez R, De Antonellis P, Michealraj A, Rastan A, Hegde M, Komosa M, Sirbu O, Kumar SA, Abdullaev Z, Faria CC, Yip S, Hukin J, Tabori U, Hawkins C, Aldape K, Daugaard M, Maris JM, Sorensen PH, Ahmed N, Taylor MD. Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma. Nat Med. 2020 05; 26(5):720-731.
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Gupta HV, Lyons KE, Pahwa R. Old Drugs, New Delivery Systems in Parkinson's Disease. Drugs Aging. 2019 09; 36(9):807-821.
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Berlinski A, Velasco J. Albuterol Delivery Efficiency in a Pediatric Model of Noninvasive Ventilation With a Single-Limb Circuit. Respir Care. 2019 Nov; 64(11):1366-1370.
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Kennon-McGill S, Clemens MM, McGill MR. Expression of drug metabolizing enzymes and transporters in the cochlea: Implications for drug delivery and ototoxicity. Hear Res. 2019 08; 379:98-102.
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Jenkins SV, Nedosekin DA, Shaulis BJ, Wang T, Jamshidi-Parsian A, Pollock ED, Chen J, Dings RPM, Griffin RJ. Enhanced Photothermal Treatment Efficacy and Normal Tissue Protection via Vascular Targeted Gold Nanocages. Nanotheranostics. 2019; 3(2):145-155.
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Nima ZA, Watanabe F, Jamshidi-Parsian A, Sarimollaoglu M, Nedosekin DA, Han M, Watts JA, Biris AS, Zharov VP, Galanzha EI. Bioinspired magnetic nanoparticles as multimodal photoacoustic, photothermal and photomechanical contrast agents. Sci Rep. 2019 01 29; 9(1):887.
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Gokulan K, Varughese KI. Drug resistance in Mycobacterium tuberculosis and targeting the l,d-transpeptidase enzyme. Drug Dev Res. 2019 02; 80(1):11-18.
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Kumari M, Purohit MP, Patnaik S, Shukla Y, Kumar P, Gupta KC. Curcumin loaded selenium nanoparticles synergize the anticancer potential of doxorubicin contained in self-assembled, cell receptor targeted nanoparticles. Eur J Pharm Biopharm. 2018 Sep; 130:185-199.
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Awad SM, Berlinski A. Crossover Evaluation of Compressors and Nebulizers Typically Used by Cystic Fibrosis Patients. Respir Care. 2018 Mar; 63(3):294-300.
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Becker RC, Sexton T, Smyth SS. Translational Implications of Platelets as Vascular First Responders. Circ Res. 2018 02 02; 122(3):506-522.
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Velasco J, Berlinski A. Albuterol Delivery Efficiency in a Pediatric Model of Noninvasive Ventilation With Double-Limb Circuit. Respir Care. 2018 Feb; 63(2):141-146.
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Kendrick S, Muranyi A, Gokhale V, Hurley LH, Rimsza LM. Simultaneous Drug Targeting of the Promoter MYC G-Quadruplex and BCL2 i-Motif in Diffuse Large B-Cell Lymphoma Delays Tumor Growth. J Med Chem. 2017 08 10; 60(15):6587-6597.
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Patil VS, Gutierrez AM, Sunkara M, Morris AJ, Hilt JZ, Kalika DS, Dziubla TD. Curcumin Acrylation for Biological and Environmental Applications. J Nat Prod. 2017 07 28; 80(7):1964-1971.
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Berlinski A, Pennington D. Effect of Interval Between Actuations of Albuterol Hydrofluoroalkane Pressurized Metered-Dose Inhalers on Their Aerosol Characteristics. Respir Care. 2017 Sep; 62(9):1123-1130.
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Galanzha EI, Weingold R, Nedosekin DA, Sarimollaoglu M, Nolan J, Harrington W, Kuchyanov AS, Parkhomenko RG, Watanabe F, Nima Z, Biris AS, Plekhanov AI, Stockman MI, Zharov VP. Spaser as a biological probe. Nat Commun. 2017 06 08; 8:15528.
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Berlinski A, Ari A, Davies P, Fink J, Majaesic C, Reychler G, Tatla T, Amirav I. Workshop Report: Aerosol Delivery to Spontaneously Breathing Tracheostomized Patients. J Aerosol Med Pulm Drug Deliv. 2017 Aug; 30(4):207-222.
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Berlinski A, von Hollen D, Hatley RHM, Hardaker LEA, Nikander K. Drug Delivery in Asthmatic Children Following Coordinated and Uncoordinated Inhalation Maneuvers: A Randomized Crossover Trial. J Aerosol Med Pulm Drug Deliv. 2017 Jun; 30(3):182-189.
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Chau DF, Vasilopoulos T, Schoepf M, Zhang C, Fahy BG. Syringe Pump Performance Maintained with IV Filter Use During Low Flow Rate Delivery for Pediatric Patients. Anesth Analg. 2016 09; 123(3):705-14.
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Berlinski A, Cooper B. Oronasal and Tracheostomy Delivery of Soft Mist and Pressurized Metered-Dose Inhalers With Valved Holding Chamber. Respir Care. 2016 Jul; 61(7):913-9.
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Leach JC, Wang A, Ye K, Jin S. A RNA-DNA Hybrid Aptamer for Nanoparticle-Based Prostate Tumor Targeted Drug Delivery. Int J Mol Sci. 2016 Mar 14; 17(3):380.
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Kotagiri N, Sakon J, Han H, Zharov VP, Kim JW. Fluorescent ampicillin analogues as multifunctional disguising agents against opsonization. Nanoscale. 2016 Jul 07; 8(25):12658-67.
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Koga CC, Andrade JE, Ferruzzi MG, Lee Y. Stability of Trans-Resveratrol Encapsulated in a Protein Matrix Produced Using Spray Drying to UV Light Stress and Simulated Gastro-Intestinal Digestion. J Food Sci. 2016 Feb; 81(2):C292-300.
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Zong H, Sen S, Zhang G, Mu C, Albayati ZF, Gorenstein DG, Liu X, Ferrari M, Crooks PA, Roboz GJ, Shen H, Guzman ML. In vivo targeting of leukemia stem cells by directing parthenolide-loaded nanoparticles to the bone marrow niche. Leukemia. 2016 07; 30(7):1582-6.
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Alghazali KM, Nima ZA, Hamzah RN, Dhar MS, Anderson DE, Biris AS. Bone-tissue engineering: complex tunable structural and biological responses to injury, drug delivery, and cell-based therapies. Drug Metab Rev. 2015; 47(4):431-54.
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Berlinski A. Transnasal Aerosol Delivery to Pediatric Patients: Jet Versus Vibrating Mesh--Reply. Respir Care. 2015 Oct; 60(10):e168-9.
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Jenkins SV, Srivatsan A, Reynolds KY, Gao F, Zhang Y, Heyes CD, Pandey RK, Chen J. Understanding the interactions between porphyrin-containing photosensitizers and polymer-coated nanoparticles in model biological environments. J Colloid Interface Sci. 2016 Jan 01; 461:225-231.
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DeLoach A, Cozart M, Kiaei A, Kiaei M. A retrospective review of the progress in amyotrophic lateral sclerosis drug discovery over the last decade and a look at the latest strategies. Expert Opin Drug Discov. 2015 Oct; 10(10):1099-118.
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Cooper B, Berlinski A. Albuterol Delivery via Facial and Tracheostomy Route in a Model of a Spontaneously Breathing Child. Respir Care. 2015 Dec; 60(12):1749-58.
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Sethi P, Jyoti A, Swindell EP, Chan R, Langner UW, Feddock JM, Nagarajan R, O'Halloran TV, Upreti M. 3D tumor tissue analogs and their orthotopic implants for understanding tumor-targeting of microenvironment-responsive nanosized chemotherapy and radiation. Nanomedicine. 2015 Nov; 11(8):2013-23.
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Resham K, Patel PN, Thummuri D, Guntuku L, Shah V, Bambal RB, Naidu VG. Preclinical drug metabolism and pharmacokinetics of salinomycin, a potential candidate for targeting human cancer stem cells. Chem Biol Interact. 2015 Oct 05; 240:146-52.
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Zhao W, Wang J, Bi W, Ferruzzi M, Yemul S, Freire D, Mazzola P, Ho L, Dubner L, Pasinetti GM. Novel application of brain-targeting polyphenol compounds in sleep deprivation-induced cognitive dysfunction. Neurochem Int. 2015 Oct; 89:191-7.
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Berlinski A. Assessing New Technologies in Aerosol Medicine: Strengths and Limitations. Respir Care. 2015 Jun; 60(6):833-47; discussion 847-9.
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Berlinski A, Willis JR. Effect of Tidal Volume and Nebulizer Type and Position on Albuterol Delivery in a Pediatric Model of Mechanical Ventilation. Respir Care. 2015 Oct; 60(10):1424-30.
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Zhou Z, Badkas A, Stevenson M, Lee JY, Leung YK. Herceptin conjugated PLGA-PHis-PEG pH sensitive nanoparticles for targeted and controlled drug delivery. Int J Pharm. 2015 Jun 20; 487(1-2):81-90.
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Bajpayee AG, Scheu M, Grodzinsky AJ, Porter RM. A rabbit model demonstrates the influence of cartilage thickness on intra-articular drug delivery and retention within cartilage. J Orthop Res. 2015 May; 33(5):660-7.
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El Taoum KK, Xi J, Kim J, Berlinski A. In Vitro Evaluation of Aerosols Delivered via the Nasal Route. Respir Care. 2015 Jul; 60(7):1015-25.
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Parker AC, Beenken KE, Jennings JA, Hittle L, Shirtliff ME, Bumgardner JD, Smeltzer MS, Haggard WO. Characterization of local delivery with amphotericin B and vancomycin from modified chitosan sponges and functional biofilm prevention evaluation. J Orthop Res. 2015 Mar; 33(3):439-47.
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Eldridge JA, Milewski M, Stinchcomb AL, Crooks PA. Synthesis and in vitro stability of amino acid prodrugs of 6-ß-naltrexol for microneedle-enhanced transdermal delivery. Bioorg Med Chem Lett. 2014 Nov 15; 24(22):5212-5.
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Ghosh D, Bagley AF, Na YJ, Birrer MJ, Bhatia SN, Belcher AM. Deep, noninvasive imaging and surgical guidance of submillimeter tumors using targeted M13-stabilized single-walled carbon nanotubes. Proc Natl Acad Sci U S A. 2014 Sep 23; 111(38):13948-53.
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Mahmood M, Mustafa T, Xu Y, Nima Z, Kannarpady G, Bourdo S, Casciano D, Biris AS. Calcium-channel blocking and nanoparticles-based drug delivery for treatment of drug-resistant human cancers. Ther Deliv. 2014 Jul; 5(7):763-80.
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Ishrat T, Mohamed IN, Pillai B, Soliman S, Fouda AY, Ergul A, El-Remessy AB, Fagan SC. Thioredoxin-interacting protein: a novel target for neuroprotection in experimental thromboembolic stroke in mice. Mol Neurobiol. 2015 Apr; 51(2):766-78.
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Beenken KE, Smith JK, Skinner RA, Mclaren SG, Bellamy W, Gruenwald MJ, Spencer HJ, Jennings JA, Haggard WO, Smeltzer MS. Chitosan coating to enhance the therapeutic efficacy of calcium sulfate-based antibiotic therapy in the treatment of chronic osteomyelitis. J Biomater Appl. 2014 Oct; 29(4):514-23.
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Felton C, Karmakar A, Gartia Y, Ramidi P, Biris AS, Ghosh A. Magnetic nanoparticles as contrast agents in biomedical imaging: recent advances in iron- and manganese-based magnetic nanoparticles. Drug Metab Rev. 2014 May; 46(2):142-54.
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Sharma M, Thandassery RB, Hilli SA, Kaabi SA. Abdominal and scrotal wall emphysema in a patient with severe ulcerative colitis. Trop Doct. 2014 Jul; 44(3):186-8.
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Zhang Y, Petibone D, Xu Y, Mahmood M, Karmakar A, Casciano D, Ali S, Biris AS. Toxicity and efficacy of carbon nanotubes and graphene: the utility of carbon-based nanoparticles in nanomedicine. Drug Metab Rev. 2014 May; 46(2):232-46.
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Nickell JR, Siripurapu KB, Vartak A, Crooks PA, Dwoskin LP. The vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse. Adv Pharmacol. 2014; 69:71-106.
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Seo BR, DelNero P, Fischbach C. In vitro models of tumor vessels and matrix: engineering approaches to investigate transport limitations and drug delivery in cancer. Adv Drug Deliv Rev. 2014 Apr; 69-70:205-216.
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Martin DT, Steinbach JM, Liu J, Shimizu S, Kaimakliotis HZ, Wheeler MA, Hittelman AB, Mark Saltzman W, Weiss RM. Surface-modified nanoparticles enhance transurothelial penetration and delivery of survivin siRNA in treating bladder cancer. Mol Cancer Ther. 2014 Jan; 13(1):71-81.
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Steinbach WJ. Are we there yet? Recent progress in the molecular diagnosis and novel antifungal targeting of Aspergillus fumigatus and invasive aspergillosis. PLoS Pathog. 2013 Oct; 9(10):e1003642.
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Berlinski A, Willis JR. Albuterol delivery by 4 different nebulizers placed in 4 different positions in a pediatric ventilator in vitro model. Respir Care. 2013 Jul; 58(7):1124-33.
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Kim J, Xi J, Si X, Berlinski A, Su WC. Hood nebulization: effects of head direction and breathing mode on particle inhalability and deposition in a 7-month-old infant model. J Aerosol Med Pulm Drug Deliv. 2014 Jun; 27(3):209-18.
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Martin DT, Hoimes CJ, Kaimakliotis HZ, Cheng CJ, Zhang K, Liu J, Wheeler MA, Kelly WK, Tew GN, Saltzman WM, Weiss RM. Nanoparticles for urothelium penetration and delivery of the histone deacetylase inhibitor belinostat for treatment of bladder cancer. Nanomedicine. 2013 Nov; 9(8):1124-34.
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