 Reperfusion Injury
"Reperfusion Injury" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.
| Descriptor ID |
D015427
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| MeSH Number(s) |
C14.907.725 C23.550.767.877
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| Concept/Terms |
Reperfusion Injury- Reperfusion Injury
- Reperfusion Damage
- Damage, Reperfusion
- Damages, Reperfusion
- Reperfusion Damages
- Ischemia-Reperfusion Injury
- Ischemia Reperfusion Injury
- Injury, Ischemia-Reperfusion
- Injuries, Ischemia-Reperfusion
- Injury, Ischemia Reperfusion
- Ischemia-Reperfusion Injuries
- Injury, Reperfusion
- Injuries, Reperfusion
- Reperfusion Injuries
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Below are MeSH descriptors whose meaning is more general than "Reperfusion Injury".
Below are MeSH descriptors whose meaning is more specific than "Reperfusion Injury".
This graph shows the total number of publications written about "Reperfusion Injury" by people in UAMS Profiles by year, and whether "Reperfusion Injury" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 1 | 0 | 1 | | 2021 | 2 | 1 | 3 | | 2020 | 1 | 2 | 3 | | 2019 | 2 | 1 | 3 | | 2018 | 2 | 1 | 3 | | 2017 | 2 | 1 | 3 | | 2016 | 1 | 0 | 1 | | 2015 | 4 | 1 | 5 | | 2014 | 2 | 1 | 3 | | 2013 | 4 | 1 | 5 | | 2012 | 5 | 1 | 6 | | 2011 | 2 | 1 | 3 | | 2010 | 0 | 1 | 1 | | 2009 | 2 | 1 | 3 | | 2008 | 1 | 2 | 3 | | 2007 | 2 | 1 | 3 | | 2006 | 2 | 2 | 4 | | 2005 | 2 | 1 | 3 | | 2004 | 2 | 2 | 4 | | 2003 | 3 | 0 | 3 | | 2002 | 3 | 1 | 4 | | 2001 | 1 | 2 | 3 | | 2000 | 1 | 2 | 3 | | 1999 | 0 | 1 | 1 | | 1998 | 4 | 1 | 5 | | 1997 | 1 | 0 | 1 | | 1996 | 2 | 0 | 2 | | 1995 | 6 | 0 | 6 | | 1994 | 4 | 0 | 4 | | 1993 | 2 | 0 | 2 | | 1992 | 1 | 0 | 1 | | 1991 | 2 | 0 | 2 |
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Below are the most recent publications written about "Reperfusion Injury" by people in Profiles over the past ten years.
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Chen W, Wang L, Liang P, Mast J, Mathis C, Liu CY, Wei J, Zhang J, Fu L, Juncos LA, Buggs J, Liu R. Reducing ischemic kidney injury through application of a synchronization modulation electric field to maintain Na+/K+-ATPase functions. Sci Transl Med. 2022 03 09; 14(635):eabj4906.
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Nowak G, Megyesi J. ?-Tocotrienol Protects against Mitochondrial Dysfunction, Energy Deficits, Morphological Damage, and Decreases in Renal Functions after Renal Ischemia. Int J Mol Sci. 2021 Nov 24; 22(23).
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Fouda AY, Eldahshan W, Xu Z, Lemtalsi T, Shosha E, Zaidi SA, Abdelrahman AA, Cheng PN, Narayanan SP, Caldwell RW, Caldwell RB. Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury. Exp Neurol. 2022 02; 348:113923.
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Shosha E, Fouda AY, Lemtalsi T, Haigh S, Fulton D, Ibrahim A, Al-Shabrawey M, Caldwell RW, Caldwell RB. Endothelial arginase 2 mediates retinal ischemia/reperfusion injury by inducing mitochondrial dysfunction. Mol Metab. 2021 11; 53:101273.
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Liss KHH, Ek SE, Lutkewitte AJ, Pietka TA, He M, Skaria P, Tycksen E, Ferguson D, Blanc V, Graham MJ, Hall AM, McGill MR, McCommis KS, Finck BN. Monoacylglycerol Acyltransferase 1 Knockdown Exacerbates Hepatic Ischemia/Reperfusion Injury in Mice With Hepatic Steatosis. Liver Transpl. 2021 01; 27(1):116-133.
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Shi L, Tian Z, Fu Q, Li H, Zhang L, Tian L, Mi W. miR-217-regulated MEF2D-HDAC5/ND6 signaling pathway participates in the oxidative stress and inflammatory response after cerebral ischemia. Brain Res. 2020 07 15; 1739:146835.
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Fouda AY, Xu Z, Narayanan SP, Caldwell RW, Caldwell RB. Utility of LysM-cre and Cdh5-cre Driver Mice in Retinal and Brain Research: An Imaging Study Using tdTomato Reporter Mouse. Invest Ophthalmol Vis Sci. 2020 03 09; 61(3):51.
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Nowak G, Megyesi J. Protein kinase Ca mediates recovery of renal and mitochondrial functions following acute injury. FEBS J. 2020 05; 287(9):1830-1849.
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Rosenfeld DM, Smith ML, Seamans DP, Giorgakis E, Gaitan BD, Khurmi N, Aqel BA, Reddy KS. Fatal diffuse pulmonary fat microemboli following reperfusion in liver transplantation with the use of marginal steatotic allografts. Am J Transplant. 2019 09; 19(9):2640-2645.
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Cameron RB, Gibbs WS, Miller SR, Dupre TV, Megyesi J, Beeson CC, Schnellmann RG. Proximal Tubule ß2-Adrenergic Receptor Mediates Formoterol-Induced Recovery of Mitochondrial and Renal Function after Ischemia-Reperfusion Injury. J Pharmacol Exp Ther. 2019 04; 369(1):173-180.
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Fouda AY, Xu Z, Shosha E, Lemtalsi T, Chen J, Toque HA, Tritz R, Cui X, Stansfield BK, Huo Y, Rodriguez PC, Smith SB, Caldwell RW, Narayanan SP, Caldwell RB. Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses. Cell Death Dis. 2018 09 25; 9(10):1001.
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Plotkin M. Young blood for old kidneys? More questions than answers so far. Kidney Int. 2018 08; 94(2):235-236.
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Gibbs WS, Collier JB, Morris M, Beeson CC, Megyesi J, Schnellmann RG. 5-HT1F receptor regulates mitochondrial homeostasis and its loss potentiates acute kidney injury and impairs renal recovery. Am J Physiol Renal Physiol. 2018 10 01; 315(4):F1119-F1128.
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Fouda AM, Youssef AR, Sharaf Eldin O. Comparative study of amlodipine vs. cilnidipine for the prevention of hepatic ischemia-reperfusion injury in rat model. Fundam Clin Pharmacol. 2018 Apr; 32(2):163-173.
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Dupre TV, Doll MA, Shah PP, Sharp CN, Siow D, Megyesi J, Shayman J, Bielawska A, Bielawski J, Beverly LJ, Hernandez-Corbacho M, Clarke CJ, Snider AJ, Schnellmann RG, Obeid LM, Hannun YA, Siskind LJ. Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury. J Lipid Res. 2017 07; 58(7):1439-1452.
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Fouda AY, Pillai B, Dhandapani KM, Ergul A, Fagan SC. Role of interleukin-10 in the neuroprotective effect of the Angiotensin Type 2 Receptor agonist, compound 21, after ischemia/reperfusion injury. Eur J Pharmacol. 2017 Mar 15; 799:128-134.
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Patil CN, Wallace K, LaMarca BD, Moulana M, Lopez-Ruiz A, Soljancic A, Juncos LA, Grande JP, Reckelhoff JF. Low-dose testosterone protects against renal ischemia-reperfusion injury by increasing renal IL-10-to-TNF-a ratio and attenuating T-cell infiltration. Am J Physiol Renal Physiol. 2016 08 01; 311(2):F395-403.
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Chandrika BB, Yang C, Ou Y, Feng X, Muhoza D, Holmes AF, Theus S, Deshmukh S, Haun RS, Kaushal GP. Endoplasmic Reticulum Stress-Induced Autophagy Provides Cytoprotection from Chemical Hypoxia and Oxidant Injury and Ameliorates Renal Ischemia-Reperfusion Injury. PLoS One. 2015; 10(10):e0140025.
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Juncos LA, Juncos LI. Mineralocorticoid Receptor Antagonism in AKI: A New Hope? J Am Soc Nephrol. 2016 Feb; 27(2):335-7.
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Culp WC, Brown AT, Lowery JD, Arthur MC, Roberson PK, Skinner RD. Dodecafluoropentane Emulsion Extends Window for tPA Therapy in a Rabbit Stroke Model. Mol Neurobiol. 2015 Oct; 52(2):979-84.
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Scindia Y, Dey P, Thirunagari A, Liping H, Rosin DL, Floris M, Okusa MD, Swaminathan S. Hepcidin Mitigates Renal Ischemia-Reperfusion Injury by Modulating Systemic Iron Homeostasis. J Am Soc Nephrol. 2015 Nov; 26(11):2800-14.
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Muroya Y, Fan F, Regner KR, Falck JR, Garrett MR, Juncos LA, Roman RJ. Deficiency in the Formation of 20-Hydroxyeicosatetraenoic Acid Enhances Renal Ischemia-Reperfusion Injury. J Am Soc Nephrol. 2015 Oct; 26(10):2460-9.
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Jesinkey SR, Funk JA, Stallons LJ, Wills LP, Megyesi JK, Beeson CC, Schnellmann RG. Formoterol restores mitochondrial and renal function after ischemia-reperfusion injury. J Am Soc Nephrol. 2014 Jun; 25(6):1157-62.
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Lee D, Shenoy S, Nigatu Y, Plotkin M. Id proteins regulate capillary repair and perivascular cell proliferation following ischemia-reperfusion injury. PLoS One. 2014; 9(2):e88417.
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Choi HY, Moon SJ, Ratliff BB, Ahn SH, Jung A, Lee M, Lee S, Lim BJ, Kim BS, Plotkin MD, Ha SK, Park HC. Microparticles from kidney-derived mesenchymal stem cells act as carriers of proangiogenic signals and contribute to recovery from acute kidney injury. PLoS One. 2014; 9(2):e87853.
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Lawton B, Boyette JR, Hu M, Lian TS. Selectin blockade decreases postischemic recruitment of bone marrow stromal cells. Laryngoscope. 2013 Dec; 123(12):2993-5.
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McGill MR, Lebofsky M, Norris HR, Slawson MH, Bajt ML, Xie Y, Williams CD, Wilkins DG, Rollins DE, Jaeschke H. Plasma and liver acetaminophen-protein adduct levels in mice after acetaminophen treatment: dose-response, mechanisms, and clinical implications. Toxicol Appl Pharmacol. 2013 Jun 15; 269(3):240-9.
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Soljancic A, Ruiz AL, Chandrashekar K, Maranon R, Liu R, Reckelhoff JF, Juncos LA. Protective role of testosterone in ischemia-reperfusion-induced acute kidney injury. Am J Physiol Regul Integr Comp Physiol. 2013 Jun 01; 304(11):R951-8.
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Kaushal GP, Shah SV. Non-apoptotic effects of antiapoptotic agent zVAD-fmk in renal injury. Kidney Int. 2013 Mar; 83(3):531.
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Arany I, Clark J, Reed DK, Juncos LA. Chronic nicotine exposure augments renal oxidative stress and injury through transcriptional activation of p66shc. Nephrol Dial Transplant. 2013 Jun; 28(6):1417-25.
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Kaushal GP. Autophagy protects proximal tubular cells from injury and apoptosis. Kidney Int. 2012 Dec; 82(12):1250-3.
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Parajuli N, MacMillan-Crow LA. Role of reduced manganese superoxide dismutase in ischemia-reperfusion injury: a possible trigger for autophagy and mitochondrial biogenesis? Am J Physiol Renal Physiol. 2013 Feb 01; 304(3):F257-67.
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Pabbidi MR, Juncos J, Juncos L, Renic M, Tullos HJ, Lazar J, Jacob HJ, Harder DR, Roman RJ. Identification of a region of rat chromosome 1 that impairs the myogenic response and autoregulation of cerebral blood flow in fawn-hooded hypertensive rats. Am J Physiol Heart Circ Physiol. 2013 Jan 15; 304(2):H311-7.
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Ekici S, Dogan Ekici AI, Öztürk G, Benli Aksungar F, Sinanoglu O, Turan G, Lüleci N. Comparison of melatonin and ozone in the prevention of reperfusion injury following unilateral testicular torsion in rats. Urology. 2012 Oct; 80(4):899-906.
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