 Reperfusion Injury
"Reperfusion Injury" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.
| Descriptor ID |
D015427
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| MeSH Number(s) |
C14.907.725 C23.550.767.877
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| Concept/Terms |
Reperfusion Injury- Reperfusion Injury
- Reperfusion Damage
- Damage, Reperfusion
- Damages, Reperfusion
- Reperfusion Damages
- Ischemia-Reperfusion Injury
- Ischemia Reperfusion Injury
- Injury, Ischemia-Reperfusion
- Injuries, Ischemia-Reperfusion
- Injury, Ischemia Reperfusion
- Ischemia-Reperfusion Injuries
- Injury, Reperfusion
- Injuries, Reperfusion
- Reperfusion Injuries
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Below are MeSH descriptors whose meaning is more general than "Reperfusion Injury".
Below are MeSH descriptors whose meaning is more specific than "Reperfusion Injury".
This graph shows the total number of publications written about "Reperfusion Injury" by people in UAMS Profiles by year, and whether "Reperfusion Injury" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 0 | 1 | 1 | | 2023 | 4 | 0 | 4 | | 2022 | 1 | 0 | 1 | | 2021 | 2 | 1 | 3 | | 2020 | 1 | 1 | 2 | | 2018 | 3 | 0 | 3 | | 2017 | 2 | 0 | 2 | | 2016 | 2 | 0 | 2 | | 2015 | 2 | 1 | 3 | | 2014 | 1 | 1 | 2 | | 2013 | 1 | 1 | 2 | | 2012 | 3 | 0 | 3 | | 2011 | 2 | 0 | 2 | | 2009 | 1 | 1 | 2 | | 2008 | 1 | 2 | 3 | | 2007 | 2 | 1 | 3 | | 2006 | 2 | 1 | 3 | | 2005 | 2 | 1 | 3 | | 2004 | 2 | 1 | 3 | | 2003 | 2 | 0 | 2 | | 2002 | 2 | 1 | 3 | | 2001 | 0 | 1 | 1 | | 2000 | 0 | 2 | 2 | | 1999 | 0 | 1 | 1 | | 1998 | 3 | 0 | 3 | | 1997 | 1 | 0 | 1 | | 1996 | 2 | 0 | 2 | | 1995 | 6 | 0 | 6 | | 1994 | 4 | 0 | 4 | | 1993 | 2 | 0 | 2 | | 1992 | 1 | 0 | 1 | | 1991 | 2 | 0 | 2 |
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Below are the most recent publications written about "Reperfusion Injury" by people in Profiles over the past ten years.
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Shahror RA, Shosha E, Morris C, Wild M, Mu S, Csanyi G, Boerma M, Rusch NJ, Fouda AY. Deletion of myeloid HDAC3 promotes efferocytosis to ameliorate retinal ischemic injury. J Neuroinflammation. 2024 Jul 12; 21(1):170.
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Guo X, Blanc V, Davidson NO, Velazquez H, Chen TM, Moledina DG, Moeckel GW, Safirstein RL, Desir GV. APOBEC-1 deletion enhances cisplatin-induced acute kidney injury. Sci Rep. 2023 12 14; 13(1):22255.
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Panayotova GG, Lunsford KE, Quillin RC, Rana A, Agopian VG, Lee-Riddle GS, Markovic D, Paterno F, Griesemer AD, Amin A, Alonso D, Rocca JP, Borja-Cacho D, Hernandez-Alejandro R, Fung JJ, Pelletier SJ, Shah SA, Guarrera JV. Portable hypothermic oxygenated machine perfusion for organ preservation in liver transplantation: A randomized, open-label, clinical trial. Hepatology. 2024 05 01; 79(5):1033-1047.
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Shosha E, Shahror RA, Morris CA, Xu Z, Lucas R, McGee-Lawrence ME, Rusch NJ, Caldwell RB, Fouda AY. The arginase 1/ornithine decarboxylase pathway suppresses HDAC3 to ameliorate the myeloid cell inflammatory response: implications for retinal ischemic injury. Cell Death Dis. 2023 09 21; 14(9):621.
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Yapca OE, Yildiz GA, Mammadov R, Kurt N, Gundogdu B, Arslan YK, Suleyman H, Cetin N. The effects of metyrosine on ischemia-reperfusion-induced oxidative ovarian injury in rats: Biochemical and histopathological assessment. An Acad Bras Cienc. 2023; 95(2):e20201586.
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Wang ZY, Liu Y, Li SP, Li JJ, Zhang Z, Xiao XC, Ou Y, Wang H, Cai JZ, Yang S. Hypoxia inducible factor 1a promotes interleukin-1 receptor antagonist expression during hepatic ischemia-reperfusion injury. World J Gastroenterol. 2022 Oct 14; 28(38):5573-5588.
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Kulek AR, Undyala VVR, Anzell AR, Raghunayakula S, MacMillan-Crow LA, Sanderson TH, Przyklenk K. Does Disruption of Optic Atrophy-1 (OPA1) Contribute to Cell Death in HL-1 Cardiomyocytes Subjected to Lethal Ischemia-Reperfusion Injury? Cells. 2022 09 30; 11(19).
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Chen W, Wang L, Liang P, Mast J, Mathis C, Liu CY, Wei J, Zhang J, Fu L, Juncos LA, Buggs J, Liu R. Reducing ischemic kidney injury through application of a synchronization modulation electric field to maintain Na+/K+-ATPase functions. Sci Transl Med. 2022 03 09; 14(635):eabj4906.
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Soranno DE, Baker P, Kirkbride-Romeo L, Wennersten SA, Ding K, Keith B, Cavasin MA, Altmann C, Bagchi RA, Haefner KR, Montford J, Gist KM, Vergnes L, Reue K, He Z, Elajaili H, Okamura K, Nozik E, McKinsey TA, Faubel S. Female and male mice have differential longterm cardiorenal outcomes following a matched degree of ischemia-reperfusion acute kidney injury. Sci Rep. 2022 Jan 12; 12(1):643.
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Nowak G, Megyesi J. ?-Tocotrienol Protects against Mitochondrial Dysfunction, Energy Deficits, Morphological Damage, and Decreases in Renal Functions after Renal Ischemia. Int J Mol Sci. 2021 Nov 24; 22(23).
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Fouda AY, Eldahshan W, Xu Z, Lemtalsi T, Shosha E, Zaidi SA, Abdelrahman AA, Cheng PN, Narayanan SP, Caldwell RW, Caldwell RB. Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury. Exp Neurol. 2022 02; 348:113923.
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Musayeva A, Unkrig JC, Zhutdieva MB, Manicam C, Ruan Y, Laspas P, Chronopoulos P, G?bel ML, Pfeiffer N, Brochhausen C, Daiber A, Oelze M, Li H, Xia N, Gericke A. Betulinic Acid Protects from Ischemia-Reperfusion Injury in the Mouse Retina. Cells. 2021 09 16; 10(9).
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Shosha E, Fouda AY, Lemtalsi T, Haigh S, Fulton D, Ibrahim A, Al-Shabrawey M, Caldwell RW, Caldwell RB. Endothelial arginase 2 mediates retinal ischemia/reperfusion injury by inducing mitochondrial dysfunction. Mol Metab. 2021 11; 53:101273.
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Liss KHH, Ek SE, Lutkewitte AJ, Pietka TA, He M, Skaria P, Tycksen E, Ferguson D, Blanc V, Graham MJ, Hall AM, McGill MR, McCommis KS, Finck BN. Monoacylglycerol Acyltransferase 1 Knockdown Exacerbates Hepatic Ischemia/Reperfusion Injury in Mice With Hepatic Steatosis. Liver Transpl. 2021 01; 27(1):116-133.
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Fouda AY, Xu Z, Narayanan SP, Caldwell RW, Caldwell RB. Utility of LysM-cre and Cdh5-cre Driver Mice in Retinal and Brain Research: An Imaging Study Using tdTomato Reporter Mouse. Invest Ophthalmol Vis Sci. 2020 03 09; 61(3):51.
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Nowak G, Megyesi J. Protein kinase Ca mediates recovery of renal and mitochondrial functions following acute injury. FEBS J. 2020 05; 287(9):1830-1849.
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Rosenfeld DM, Smith ML, Seamans DP, Giorgakis E, Gaitan BD, Khurmi N, Aqel BA, Reddy KS. Fatal diffuse pulmonary fat microemboli following reperfusion in liver transplantation with the use of marginal steatotic allografts. Am J Transplant. 2019 09; 19(9):2640-2645.
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Cameron RB, Gibbs WS, Miller SR, Dupre TV, Megyesi J, Beeson CC, Schnellmann RG. Proximal Tubule ?2-Adrenergic Receptor Mediates Formoterol-Induced Recovery of Mitochondrial and Renal Function after Ischemia-Reperfusion Injury. J Pharmacol Exp Ther. 2019 04; 369(1):173-180.
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Fouda AY, Xu Z, Shosha E, Lemtalsi T, Chen J, Toque HA, Tritz R, Cui X, Stansfield BK, Huo Y, Rodriguez PC, Smith SB, Caldwell RW, Narayanan SP, Caldwell RB. Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses. Cell Death Dis. 2018 09 25; 9(10):1001.
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Rajab TK, Okamoto T, Ren X, Mathisen DJ, Ott HC. Intralipid improves oxygenation after orthotopic rat lung transplantation. J Heart Lung Transplant. 2019 02; 38(2):225-227.
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Plotkin M. Young blood for old kidneys? More questions than answers so far. Kidney Int. 2018 08; 94(2):235-236.
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Gibbs WS, Collier JB, Morris M, Beeson CC, Megyesi J, Schnellmann RG. 5-HT1F receptor regulates mitochondrial homeostasis and its loss potentiates acute kidney injury and impairs renal recovery. Am J Physiol Renal Physiol. 2018 10 01; 315(4):F1119-F1128.
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Fouda AM, Youssef AR, Sharaf Eldin O. Comparative study of amlodipine vs. cilnidipine for the prevention of hepatic ischemia-reperfusion injury in rat model. Fundam Clin Pharmacol. 2018 Apr; 32(2):163-173.
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Dupre TV, Doll MA, Shah PP, Sharp CN, Siow D, Megyesi J, Shayman J, Bielawska A, Bielawski J, Beverly LJ, Hernandez-Corbacho M, Clarke CJ, Snider AJ, Schnellmann RG, Obeid LM, Hannun YA, Siskind LJ. Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury. J Lipid Res. 2017 07; 58(7):1439-1452.
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Fouda AY, Pillai B, Dhandapani KM, Ergul A, Fagan SC. Role of interleukin-10 in the neuroprotective effect of the Angiotensin Type 2 Receptor agonist, compound 21, after ischemia/reperfusion injury. Eur J Pharmacol. 2017 Mar 15; 799:128-134.
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Daly MC, Atkinson SJ, Varisco BM, Klingbeil L, Hake P, Lahni P, Piraino G, Wu D, Hogan SP, Zingarelli B, Wong HR. Role of matrix metalloproteinase-8 as a mediator of injury in intestinal ischemia and reperfusion. FASEB J. 2016 10; 30(10):3453-3460.
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Patil CN, Wallace K, LaMarca BD, Moulana M, Lopez-Ruiz A, Soljancic A, Juncos LA, Grande JP, Reckelhoff JF. Low-dose testosterone protects against renal ischemia-reperfusion injury by increasing renal IL-10-to-TNF-a ratio and attenuating T-cell infiltration. Am J Physiol Renal Physiol. 2016 08 01; 311(2):F395-403.
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Zhao EY, Efendizade A, Cai L, Ding Y. The role of Akt (protein kinase B) and protein kinase C in ischemia-reperfusion injury. Neurol Res. 2016 Apr; 38(4):301-8.
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Chandrika BB, Yang C, Ou Y, Feng X, Muhoza D, Holmes AF, Theus S, Deshmukh S, Haun RS, Kaushal GP. Endoplasmic Reticulum Stress-Induced Autophagy Provides Cytoprotection from Chemical Hypoxia and Oxidant Injury and Ameliorates Renal Ischemia-Reperfusion Injury. PLoS One. 2015; 10(10):e0140025.
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Juncos LA, Juncos LI. Mineralocorticoid Receptor Antagonism in AKI: A New Hope? J Am Soc Nephrol. 2016 Feb; 27(2):335-7.
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