 Drug Carriers
"Drug Carriers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
| Descriptor ID |
D004337
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| MeSH Number(s) |
D26.255.260 D27.720.280.260 E02.319.300.380
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Drug Carriers".
Below are MeSH descriptors whose meaning is more specific than "Drug Carriers".
This graph shows the total number of publications written about "Drug Carriers" by people in UAMS Profiles by year, and whether "Drug Carriers" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2018 | 0 | 2 | 2 | | 2017 | 5 | 0 | 5 | | 2016 | 1 | 2 | 3 | | 2015 | 4 | 2 | 6 | | 2014 | 4 | 0 | 4 | | 2013 | 1 | 3 | 4 | | 2012 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 | | 2009 | 2 | 1 | 3 | | 2008 | 0 | 3 | 3 | | 2007 | 1 | 0 | 1 | | 2006 | 2 | 1 | 3 | | 2005 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1997 | 0 | 2 | 2 | | 1994 | 0 | 3 | 3 |
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Below are the most recent publications written about "Drug Carriers" by people in Profiles over the past ten years.
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Zhang W, Campbell DH, Walsh BJ, Packer NH, Liu D, Wang Y. Cancer-derived small extracellular vesicles: emerging biomarkers and therapies for pancreatic ductal adenocarcinoma diagnosis/prognosis and treatment. J Nanobiotechnology. 2022 Oct 14; 20(1):446.
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Alam M, Zameer S, Najmi AK, Ahmad FJ, Imam SS, Akhtar M. Thymoquinone Loaded Solid Lipid Nanoparticles Demonstrated Antidepressant-Like Activity in Rats via Indoleamine 2, 3- Dioxygenase Pathway. Drug Res (Stuttg). 2020 May; 70(5):206-213.
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He T, Zhang C, Vedadghavami A, Mehta S, Clark HA, Porter RM, Bajpayee AG. Multi-arm Avidin nano-construct for intra-cartilage delivery of small molecule drugs. J Control Release. 2020 02; 318:109-123.
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Taghizadehghalehjoughi A, Hacimuftuoglu A, Cetin M, Ugur AB, Galateanu B, Mezhuev Y, Okkay U, Taspinar N, Taspinar M, Uyanik A, Gundogdu B, Mohammadzadeh M, Nalci KA, Stivaktakis P, Tsatsakis A, Jung TW, Jeong JH, Abd El-Aty AM. Effect of metformin/irinotecan-loaded poly-lactic-co-glycolic acid nanoparticles on glioblastoma: in vitro and in vivo studies. Nanomedicine (Lond). 2018 07; 13(13):1595-1606.
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Khan MA, Zafaryab M, Mehdi SH, Ahmad I, Rizvi MMA. Physicochemical Characterization of Curcumin Loaded Chitosan Nanoparticles: Implications in Cervical Cancer. Anticancer Agents Med Chem. 2018; 18(8):1131-1137.
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Bajpayee AG, De la Vega RE, Scheu M, Varady NH, Yannatos IA, Brown LA, Krishnan Y, Fitzsimons TJ, Bhattacharya P, Frank EH, Grodzinsky AJ, Porter RM. Sustained intra-cartilage delivery of low dose dexamethasone using a cationic carrier for treatment of post traumatic osteoarthritis. Eur Cell Mater. 2017 12 05; 34:341-364.
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Nima ZA, Alwbari AM, Dantuluri V, Hamzah RN, Sra N, Motwani P, Arnaoutakis K, Levy RA, Bohliqa AF, Nedosekin D, Zharov VP, Makhoul I, Biris AS. Targeting nano drug delivery to cancer cells using tunable, multi-layer, silver-decorated gold nanorods. J Appl Toxicol. 2017 Dec; 37(12):1370-1378.
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Harris MA, Beenken KE, Smeltzer MS, Haggard WO, Jennings JA. Phosphatidylcholine Coatings Deliver Local Antimicrobials and Reduce Infection in a Murine Model: A Preliminary Study. Clin Orthop Relat Res. 2017 Jul; 475(7):1847-1853.
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Berretta JM, Jennings JA, Courtney HS, Beenken KE, Smeltzer MS, Haggard WO. Blended Chitosan Paste for Infection Prevention: Preliminary and Preclinical Evaluations. Clin Orthop Relat Res. 2017 Jul; 475(7):1857-1870.
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Khan MA, Zafaryab M, Mehdi SH, Quadri J, Rizvi MM. Characterization and carboplatin loaded chitosan nanoparticles for the chemotherapy against breast cancer in vitro studies. Int J Biol Macromol. 2017 Apr; 97:115-122.
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Lahiani MH, Eassa S, Parnell C, Nima Z, Ghosh A, Biris AS, Khodakovskaya MV. Carbon nanotubes as carriers of Panax ginseng metabolites and enhancers of ginsenosides Rb1 and Rg1 anti-cancer activity. Nanotechnology. 2017 Jan 06; 28(1):015101.
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Khan MA, Zafaryab M, Mehdi SH, Ahmad I, Rizvi MM. Characterization and anti-proliferative activity of curcumin loaded chitosan nanoparticles in cervical cancer. Int J Biol Macromol. 2016 Dec; 93(Pt A):242-253.
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Mallick N, Anwar M, Asfer M, Mehdi SH, Rizvi MMA, Panda AK, Talegaonkar S, Ahmad FJ. Chondroitin sulfate-capped super-paramagnetic iron oxide nanoparticles as potential carriers of doxorubicin hydrochloride. Carbohydr Polym. 2016 Oct 20; 151:546-556.
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Albayati ZA, Sunkara M, Schmidt-Malan SM, Karau MJ, Morris AJ, Steckelberg JM, Patel R, Breen PJ, Smeltzer MS, Taylor KG, Merten KE, Pierce WM, Crooks PA. Novel Bone-Targeting Agent for Enhanced Delivery of Vancomycin to Bone. Antimicrob Agents Chemother. 2015 Dec 14; 60(3):1865-8.
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Nedosekin DA, Foster S, Nima ZA, Biris AS, Galanzha EI, Zharov VP. Photothermal confocal multicolor microscopy of nanoparticles and nanodrugs in live cells. Drug Metab Rev. 2015 08; 47(3):346-55.
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Jennings JA, Carpenter DP, Troxel KS, Beenken KE, Smeltzer MS, Courtney HS, Haggard WO. Novel Antibiotic-loaded Point-of-care Implant Coating Inhibits Biofilm. Clin Orthop Relat Res. 2015 Jul; 473(7):2270-82.
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Oh B, Melchert RB, Lee CH. Biomimicking Robust Hydrogel for the Mesenchymal Stem Cell Carrier. Pharm Res. 2015 Oct; 32(10):3213-27.
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Zhou Z, Badkas A, Stevenson M, Lee JY, Leung YK. Herceptin conjugated PLGA-PHis-PEG pH sensitive nanoparticles for targeted and controlled drug delivery. Int J Pharm. 2015 Jun 20; 487(1-2):81-90.
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Rychahou P, Haque F, Shu Y, Zaytseva Y, Weiss HL, Lee EY, Mustain W, Valentino J, Guo P, Evers BM. Delivery of RNA nanoparticles into colorectal cancer metastases following systemic administration. ACS Nano. 2015 Feb 24; 9(2):1108-16.
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Saeed LM, Mahmood M, Pyrek SJ, Fahmi T, Xu Y, Mustafa T, Nima ZA, Bratton SM, Casciano D, Dervishi E, Radominska-Pandya A, Biris AS. Single-walled carbon nanotube and graphene nanodelivery of gambogic acid increases its cytotoxicity in breast and pancreatic cancer cells. J Appl Toxicol. 2014 Nov; 34(11):1188-99.
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Gozuacik D, Yagci-Acar HF, Akkoc Y, Kosar A, Dogan-Ekici AI, Ekici S. Anticancer use of nanoparticles as nucleic acid carriers. J Biomed Nanotechnol. 2014 Sep; 10(9):1751-83.
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Bajpayee AG, Scheu M, Grodzinsky AJ, Porter RM. Electrostatic interactions enable rapid penetration, enhanced uptake and retention of intra-articular injected avidin in rat knee joints. J Orthop Res. 2014 Aug; 32(8):1044-51.
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Orza A, Casciano D, Biris A. Nanomaterials for targeted drug delivery to cancer stem cells. Drug Metab Rev. 2014 May; 46(2):191-206.
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