 Liver
"Liver" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
No definition found.
| Descriptor ID |
D008099
|
| MeSH Number(s) |
A03.620
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Liver".
Below are MeSH descriptors whose meaning is more specific than "Liver".
This graph shows the total number of publications written about "Liver" by people in UAMS Profiles by year, and whether "Liver" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 0 | 6 | 6 | | 2022 | 2 | 19 | 21 | | 2021 | 6 | 19 | 25 | | 2020 | 9 | 19 | 28 | | 2019 | 12 | 25 | 37 | | 2018 | 17 | 10 | 27 | | 2017 | 15 | 18 | 33 | | 2016 | 26 | 20 | 46 | | 2015 | 25 | 16 | 41 | | 2014 | 20 | 26 | 46 | | 2013 | 17 | 22 | 39 | | 2012 | 16 | 24 | 40 | | 2011 | 20 | 15 | 35 | | 2010 | 17 | 16 | 33 | | 2009 | 15 | 12 | 27 | | 2008 | 14 | 14 | 28 | | 2007 | 18 | 13 | 31 | | 2006 | 16 | 20 | 36 | | 2005 | 13 | 14 | 27 | | 2004 | 18 | 18 | 36 | | 2003 | 9 | 18 | 27 | | 2002 | 11 | 5 | 16 | | 2001 | 6 | 8 | 14 | | 2000 | 8 | 6 | 14 | | 1999 | 5 | 6 | 11 | | 1998 | 5 | 3 | 8 | | 1997 | 7 | 6 | 13 | | 1996 | 5 | 4 | 9 | | 1995 | 8 | 7 | 15 | | 1994 | 5 | 7 | 12 | | 1993 | 10 | 6 | 16 | | 1992 | 7 | 6 | 13 | | 1991 | 6 | 5 | 11 | | 1990 | 7 | 6 | 13 | | 1989 | 4 | 3 | 7 | | 1988 | 1 | 4 | 5 |
To return to the timeline, click here.
Below are the most recent publications written about "Liver" by people in Profiles over the past ten years.
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Shao L, Paik NY, Sanborn MA, Bandara T, Vijaykumar A, Sottoriva K, Rehman J, Nombela-Arrieta C, Pajcini KV. Hematopoietic Jagged1 is a fetal liver niche factor required for functional maturation and engraftment of fetal hematopoietic stem cells. Proc Natl Acad Sci U S A. 2023 05 16; 120(20):e2210058120.
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Kweon SM, Irimia-Dominguez J, Kim G, Fueger PT, Asahina K, Lai KK, Allende DS, Lai QR, Lou CH, Tsark WM, Yang JD, Ng DS, Lee JS, Tso P, Huang W, Lai KKY. Heterozygous midnolin knockout attenuates severity of nonalcoholic fatty liver disease in mice fed a Western-style diet high in fat, cholesterol, and fructose. Am J Physiol Gastrointest Liver Physiol. 2023 Aug 01; 325(2):G147-G157.
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Abdelmalek MF, Suzuki A, Sanchez W, Lawitz E, Filozof C, Cho H, Baek E, Choi J, Baek S. A phase 2, adaptive randomized, double-blind, placebo-controlled, multicenter, 52-week study of HM15211 in patients with biopsy-confirmed non-alcoholic steatohepatitis - Study design and rationale of HM-TRIA-201 study. Contemp Clin Trials. 2023 07; 130:107176.
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Simmen FA, Pabona JMP, Al-Dwairi A, Alhallak I, Montales MTE, Simmen RCM. Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice. Int J Mol Sci. 2023 Apr 01; 24(7).
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Lee SM, Muratalla J, Karimi S, Diaz-Ruiz A, Frutos MD, Guzman G, Ramos-Molina B, Cordoba-Chacon J. Hepatocyte PPAR? contributes to the progression of non-alcoholic steatohepatitis in male and female obese mice. Cell Mol Life Sci. 2023 Jan 11; 80(2):39.
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Tryndyak VP, Willett RA, Nagumalli SK, Li D, Avigan MI, Beland FA, Rusyn I, Pogribny IP. Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice. Am J Physiol Gastrointest Liver Physiol. 2023 03 01; 324(3):G232-G243.
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Fuller KNZ, McCoin CS, Stierwalt H, Allen J, Gandhi S, Perry CGR, Jambal P, Shankar K, Thyfault JP. Oral combined contraceptives induce liver mitochondrial reactive oxygen species and whole-body metabolic adaptations in female mice. J Physiol. 2022 12; 600(24):5215-5245.
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Bromfield B, Tellez R, Novelli P, Duarte-Rojo A. Hepatic artery pseudoaneurysms and hepatic ischaemic injury: a rare complication of polyarteritis nodosa. BMJ Case Rep. 2022 Nov 30; 15(11).
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Griffiths ER, Lambert LM, Ou Z, Shaaban A, Rezvani M, Carlo WF, Schumacher KR, DiPaola F, O'Connor MJ, Nandi D, Zangwill S, McCulloch MA, Friedland-Little JM, West SC, Lee TM, Alejos JC, Chen S, Molina KM. Fontan-associated liver disease after heart transplant. Pediatr Transplant. 2023 03; 27(2):e14435.
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Celaj S, Ganesh S, Hughes CB, Weidensall J, Caruso C, Humar A, Duarte-Rojo A. Nationwide marketing as a tool to increase literacy and awareness for living liver donation. Ann Hepatol. 2022 Nov-Dec; 27(6):100768.
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Tas E, Bai S, Mak D, Diaz EC, Dranoff JA. Obesity, but not glycemic control, predicts liver steatosis in children with type 1 diabetes. J Diabetes Complications. 2022 Dec; 36(12):108341.
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Wang ZY, Liu Y, Li SP, Li JJ, Zhang Z, Xiao XC, Ou Y, Wang H, Cai JZ, Yang S. Hypoxia inducible factor 1a promotes interleukin-1 receptor antagonist expression during hepatic ischemia-reperfusion injury. World J Gastroenterol. 2022 Oct 14; 28(38):5573-5588.
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Fetzer DT, Rosado-Mendez IM, Wang M, Robbin ML, Ozturk A, Wear KA, Ormachea J, Stiles TA, Fowlkes JB, Hall TJ, Samir AE. Pulse-Echo Quantitative US Biomarkers for Liver Steatosis: Toward Technical Standardization. Radiology. 2022 11; 305(2):265-276.
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Kelley JT, Fuller LD, Lai KK, Yantiss RK, Dzedzik S, Alapat D, Mashayekhi A, Alpert L, Gonzalez RS, Owens SR, Arber DA, Lamps LW. Gastrointestinal, hepatic, and pancreatobiliary involvement by plasma cell neoplasms: clinicopathologic correlations in a retrospective cohort of 116 cases. Histopathology. 2022 Dec; 81(6):742-757.
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Cheema HI, Haselow D, Dranoff JA. Review of existing evidence demonstrates that methotrexate does not cause liver fibrosis. J Investig Med. 2022 10; 70(7):1452-1460.
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Woolbright BL, Nguyen NT, McGill MR, Sharpe MR, Curry SC, Jaeschke H. Generation of pro-and anti-inflammatory mediators after acetaminophen overdose in surviving and non-surviving patients. Toxicol Lett. 2022 Aug 15; 367:59-66.
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Manjar?n R, Dillard K, Coffin M, Hernandez GV, Smith VA, Noland-Lidell T, Gehani TR, Smart HJ, Wheeler K, Sprayberry KA, Edwards MS, Fanter RK, Glanz H, Immoos C, Santiago-Rodriguez TM, Blank JM, Burrin DG, Piccolo BD, Abo-Ismail M, La Frano MR, Maj M. Dietary fat composition shapes bile acid metabolism and severity of liver injury in a pig model of pediatric NAFLD. Am J Physiol Endocrinol Metab. 2022 09 01; 323(3):E187-E206.
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Nagumalli SK, Willett RA, de Conti A, Tryndyak VP, Avigan MI, da Costa GG, Beland FA, Rusyn I, Pogribny IP. Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice. J Nutr Biochem. 2022 11; 109:109108.
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Tuteja S, Yu Z, Wilson O, Chen HC, Wendt F, Chung CP, Shah SC, Hunt CM, Suzuki A, Chanfreau C, Gorman BR, Joseph J, Luoh SW, Napolioni V, Robinson-Cohen C, Tao R, Zhou J, Chang KM, Hung AM. Pharmacogenetic variants and risk of remdesivir-associated liver enzyme elevations in Million Veteran Program participants hospitalized with COVID-19. Clin Transl Sci. 2022 08; 15(8):1880-1886.
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Giorgakis E, Ivanics T, Khorsandi SE, Wallace D, Burdine L, Jassem W, Mathur AK, Heaton N. Disparities in the Use of Older Donation After Circulatory Death Liver Allografts in the United States Versus the United Kingdom. Transplantation. 2022 08 01; 106(8):e358-e367.
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Tryndyak VP, Willett RA, Avigan MI, Sanyal AJ, Beland FA, Rusyn I, Pogribny IP. Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet. Epigenetics. 2022 11; 17(11):1462-1476.
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McGill MR, Findley DL, Mazur A, Yee EU, Allard FD, Powers A, Coward L, Blough ER, Gorman G, Hambuchen MD. Radiation Effects on Methamphetamine Pharmacokinetics and Pharmacodynamics in Rats. Eur J Drug Metab Pharmacokinet. 2022 May; 47(3):319-330.
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Morales-Arr?ez D, Ventura-Cots M, Altamirano J, Abraldes JG, Cruz-Lemini M, Thursz MR, Atkinson SR, Sarin SK, Kim W, Chavez-Araujo R, Higuera-de la Tijera MF, Singal AK, Shah VH, Kamath PS, Duarte-Rojo A, Charles EA, Vargas V, Jager M, Rautou PE, Rincon D, Zamarripa F, Restrepo-Guti?rrez JC, Torre A, Lucey MR, Arab JP, Mathurin P, Louvet A, Garc?a-Tsao G, Gonz?lez JA, Verna EC, Brown RS, Argemi J, Fern?ndez-Carillo C, Clemente A, Alvarado-Tapias E, Forrest E, Allison M, Bataller R. The MELD Score Is Superior to the Maddrey Discriminant Function Score to Predict Short-Term Mortality in Alcohol-Associated Hepatitis: A Global Study. Am J Gastroenterol. 2022 02 01; 117(2):301-310.
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Duarte-Rojo A, Heimbach JK, Borja-Cacho D, Barone GW, Shaheen MF, Lamps LW, Graham RP, Tan EK, Concepcion W, Kim WR. Usefulness of Controlled Attenuation Parameter and Liver Stiffness Measurement for the Identification of Extended-criteria Donors and Risk-assessment in Liver Transplantation. Transplantation. 2022 02 01; 106(2):318-327.
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Lee C, Kim J, Han J, Oh D, Kim M, Jeong H, Kim TJ, Kim SW, Kim JN, Seo YS, Suzuki A, Kim JH, Jung Y. Formyl peptide receptor 2 determines sex-specific differences in the progression of nonalcoholic fatty liver disease and steatohepatitis. Nat Commun. 2022 01 31; 13(1):578.
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Smiech M, Leszczynski P, Wardell C, Poznanski P, Pierzchala M, Taniguchi H. Oncogenic Mutation BRAF V600E Changes Phenotypic Behavior of THLE-2 Liver Cells through Alteration of Gene Expression. Int J Mol Sci. 2022 Jan 28; 23(3).
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?akir I, Hadley CK, Pan PL, Bagchi RA, Ghamari-Langroudi M, Porter DT, Wang Q, Litt MJ, Jana S, Hagen S, Lee P, White A, Lin JD, McKinsey TA, Cone RD. Histone deacetylase 6 inhibition restores leptin sensitivity and reduces obesity. Nat Metab. 2022 01; 4(1):44-59.
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Rowan DJ, Mangalaparthi KK, Singh S, Moreira RK, Mounajjed T, Lamps L, Westerhoff M, Cheng J, Bellizzi AM, Allende DS, Pandey A, Graham RP. Metallothionein immunohistochemistry has high sensitivity and specificity for detection of Wilson disease. Mod Pathol. 2022 07; 35(7):946-955.
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Kozaczek M, Kong B, Bottje W, Hakkak R. Hepatic Proteomics Analysis of Nonalcoholic Fatty Liver Disease Obese Rat Model After Short- and Long-Term Soy Protein Isolate Feeding. J Med Food. 2022 Mar; 25(3):293-302.
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Kronfol MM, Abudahab S, Dozmorov MG, Jahr FM, Halquist MS, McRae M, Wijesinghe DS, Price ET, Slattum PW, McClay JL. Histone acetylation at the sulfotransferase 1a1 gene is associated with its hepatic expression in normal aging. Pharmacogenet Genomics. 2021 12 01; 31(9):207-214.
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Lee SM, Muratalla J, Diaz-Ruiz A, Remon-Ruiz P, McCann M, Liew CW, Kineman RD, Cordoba-Chacon J. Rosiglitazone Requires Hepatocyte PPAR? Expression to Promote Steatosis in Male Mice With Diet-Induced Obesity. Endocrinology. 2021 11 01; 162(11).
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Tiwari-Heckler S, Yee EU, Yalcin Y, Park J, Nguyen DT, Gao W, Csizmadia E, Afdhal N, Mukamal KJ, Robson SC, Lai M, Schwartz RE, Jiang ZG. Adenosine deaminase 2 produced by infiltrative monocytes promotes liver fibrosis in nonalcoholic fatty liver disease. Cell Rep. 2021 10 26; 37(4):109897.
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Cohen CC, Perng W, Sundaram SS, Scherzinger A, Shankar K, Dabelea D. Hepatic Fat in Early Childhood Is Independently Associated With Estimated Insulin Resistance: The Healthy Start Study. J Clin Endocrinol Metab. 2021 10 21; 106(11):3140-3150.
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Ruiz de Azua MJ, Cruz-Carri?n ?, Muguerza B, Arola-Arnal A, Suarez M. Seasonal Consumption of Cherries from Different Origins Affects Metabolic Markers and Gene Expression of Lipogenic Enzymes in Rat Liver: A Preliminary Study. Nutrients. 2021 Oct 18; 13(10).
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Pothineni NVK, Rochlani Y, Subramany S, Kovelamudi S, Mehta JL. Hepatic Interactions in Atherosclerotic Heart Disease. Am J Med Sci. 2022 02; 363(2):104-113.
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Rowan DJ, Allende DS, Bellizzi AM, Gill RM, Liu X, McKenzie CA, Moreira RK, Mounajjed T, Said S, Westerhoff M, Jenkins SM, Batts KP, Burgart LJ, Lamps LW, Graham RP. Diagnostic challenges of focal nodular hyperplasia: interobserver variability, accuracy, and the utility of glutamine synthetase immunohistochemistry. Histopathology. 2021 Nov; 79(5):791-800.
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Datta A, Flynn NR, Barnette DA, Woeltje KF, Miller GP, Swamidass SJ. Machine learning liver-injuring drug interactions with non-steroidal anti-inflammatory drugs (NSAIDs) from a retrospective electronic health record (EHR) cohort. PLoS Comput Biol. 2021 07; 17(7):e1009053.
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Cilingiroglu M, Okutucu S. TAVR in patients with end stage liver and renal disease: Lifesaving and increasing transplant eligibility. Catheter Cardiovasc Interv. 2021 07 01; 98(1):168-169.
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Zolotarev KV, Mikhailov AN, Mikhailova MV, Nakhod KV, Nakhod VI, Bodoev NV, Zhdanov DD. Tissue-Specific Expression of Genes Involved in Cellular Transportation in Common Carp (Cyprinus carpio) Exposed to Cadmium. Bull Environ Contam Toxicol. 2021 Jun; 106(6):978-982.
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Qi Q, Weinstock AK, Chupetlovska K, Borhani AA, Jorgensen DR, Furlan A, Behari J, Molinari M, Ganesh S, Humar A, Duarte-Rojo A. Magnetic resonance imaging-derived proton density fat fraction (MRI-PDFF) is a viable alternative to liver biopsy for steatosis quantification in living liver donor transplantation. Clin Transplant. 2021 07; 35(7):e14339.
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Ashktorab H, Pizuorno A, Aduli F, Laiyemo AO, Oskrochi G, Brim H. Elevated Liver Enzymes, Ferritin, C-reactive Protein, D-dimer, and Age Are Predictive Markers of Outcomes Among African American and Hispanic Patients With Coronavirus Disease 2019. Gastroenterology. 2021 07; 161(1):345-349.
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Kozaczek M, Bottje W, Kong B, Albataineh D, Hakkak R. A Comparison of Short- and Long-Term Soy Protein Isolate Intake and Its Ability to Reduce Liver Steatosis in Obese Zucker Rats Through Modifications of Genes Involved in Inflammation and Lipid Transport. J Med Food. 2021 Sep; 24(9):1010-1016.
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Jirapinyo P, McCarty TR, Dolan RD, Shah R, Thompson CC. Effect of Endoscopic Bariatric and Metabolic Therapies on Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2022 03; 20(3):511-524.e1.
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Gonzalez-Jimenez A, Suzuki A, Chen M, Ashby K, Alvarez-Alvarez I, Andrade RJ, Lucena MI. Drug properties and host factors contribute to biochemical presentation of drug-induced liver injury: a prediction model from a machine?learning approach. Arch Toxicol. 2021 05; 95(5):1793-1803.
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Mercer KE, Maurer A, Pack LM, Ono-Moore K, Spray BJ, Campbell C, Chandler CJ, Burnett D, Souza E, Casazza G, Keim N, Newman J, Hunter G, Fernadez J, Garvey WT, Harper ME, Hoppel C, Adams SH, Thyfault J. Exercise training and diet-induced weight loss increase markers of hepatic bile acid (BA) synthesis and reduce serum total BA concentrations in obese women. Am J Physiol Endocrinol Metab. 2021 05 01; 320(5):E864-E873.
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Soeters PB, Shenkin A, Sobotka L, Soeters MR, de Leeuw PW, Wolfe RR. The anabolic role of the Warburg, Cori-cycle and Crabtree effects in health and disease. Clin Nutr. 2021 05; 40(5):2988-2998.
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Tran D, Nguyen H, Tran B, La Vecchia C, Luu HN, Nguyen T. Fast and precise single-cell data analysis using a hierarchical autoencoder. Nat Commun. 2021 02 15; 12(1):1029.
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Ten Have GAM, Jansen L, Schooneman MG, Engelen MPKJ, Deutz NEP. Metabolic flux analysis of branched-chain amino and keto acids (BCAA, BCKA) and ?-hydroxy ?-methylbutyric acid across multiple organs in the pig. Am J Physiol Endocrinol Metab. 2021 03 01; 320(3):E629-E640.
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Giorgakis E, Khorsandi SE, Mathur AK, Burdine L, Jassem W, Heaton N. Comparable graft survival is achievable with the usage of donation after circulatory death liver grafts from donors at or above 70 years of age: A long-term UK national analysis. Am J Transplant. 2021 06; 21(6):2200-2210.
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Wang W, Li J, Tan J, Wang M, Yang J, Zhang ZM, Li C, Basnakian AG, Tang HW, Perrimon N, Zhou Q. Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response. Nat Commun. 2021 01 20; 12(1):476.
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Johnson KD, Perisetti A, Goyal H, Thandassery R, Gajendran M, Aziz M, Tharian B, Inamdar S. Liver Biopsy in Pregnancy: Two Case Reports and Review of the Literature. Dig Dis Sci. 2021 12; 66(12):4090-4098.
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Coker MS, Ladd K, Murphy CJ, Ruby BC, Shriver TC, Schoeller DA, Newcomer BR, Bateman T, Bartlett L, Coker RH. Alaska backcountry expeditionary hunting promotes rapid improvements in metabolic biomarkers in healthy males and females. Physiol Rep. 2021 01; 9(1):e14682.
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Kim IY, Park S, Kim Y, Chang Y, Choi CS, Suh SH, Wolfe RR. In Vivo and In Vitro Quantification of Glucose Kinetics: From Bedside to Bench. Endocrinol Metab (Seoul). 2020 12; 35(4):733-749.
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Cross KM, Granados JZ, Ten Have GAM, Thaden JJ, Engelen MPKJ, Lightfoot JT, Deutz NEP. Protein fractional synthesis rates within tissues of high- and low-active mice. PLoS One. 2020; 15(11):e0242926.
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Alebrahim M, Akateh C, Arnold CA, Benissan-Messan D, Chavez JA, Singh N, Al-Adwan Y, El-Hinnawi A, Michaels A, Black SM. Liver Transplant for Management of Hepatic Complications of Dyskeratosis Congenita: A Case Report. Exp Clin Transplant. 2022 07; 20(7):702-705.
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Mueller NT, Liu T, Mitchel EB, Yates KP, Suzuki A, Behling C, Lavine JE. Sex Hormone Relations to Histologic Severity of Pediatric Nonalcoholic Fatty Liver Disease. J Clin Endocrinol Metab. 2020 11 01; 105(11).
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Kardashian A, Ge J, McCulloch CE, Kappus MR, Dunn MA, Duarte-Rojo A, Volk ML, Rahimi RS, Verna EC, Ganger DR, Ladner D, Dodge JL, Boyarsky B, McAdams-DeMarco M, Segev DL, Lai JC. Identifying an Optimal Liver Frailty Index Cutoff to Predict Waitlist Mortality in Liver Transplant Candidates. Hepatology. 2021 03; 73(3):1132-1139.
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Liss KHH, Ek SE, Lutkewitte AJ, Pietka TA, He M, Skaria P, Tycksen E, Ferguson D, Blanc V, Graham MJ, Hall AM, McGill MR, McCommis KS, Finck BN. Monoacylglycerol Acyltransferase 1 Knockdown Exacerbates Hepatic Ischemia/Reperfusion Injury in Mice With Hepatic Steatosis. Liver Transpl. 2021 01; 27(1):116-133.
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McGill MR, Hinson JA. The development and hepatotoxicity of acetaminophen: reviewing over a century of progress. Drug Metab Rev. 2020 11; 52(4):472-500.
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Sarkar MA, Suzuki A, Abdelmalek MF, Yates KP, Wilson LA, Bass NM, Gill R, Cedars M, Terrault N. Testosterone is Associated With Nonalcoholic Steatohepatitis and Fibrosis in Premenopausal Women With NAFLD. Clin Gastroenterol Hepatol. 2021 06; 19(6):1267-1274.e1.
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Tas E, Bai S, Ou X, Mercer K, Lin H, Mansfield K, Buchmann R, Diaz EC, Oden J, B?rsheim E, Adams SH, Dranoff J. Fibroblast Growth Factor-21 to Adiponectin Ratio: A Potential Biomarker to Monitor Liver Fat in Children With Obesity. Front Endocrinol (Lausanne). 2020; 11:654.
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Faughnan ME, Mager JJ, Hetts SW, Palda VA, Lang-Robertson K, Buscarini E, Deslandres E, Kasthuri RS, Lausman A, Poetker D, Ratjen F, Chesnutt MS, Clancy M, Whitehead KJ, Al-Samkari H, Chakinala M, Conrad M, Cortes D, Crocione C, Darling J, de Gussem E, Derksen C, Dupuis-Girod S, Foy P, Geisthoff U, Gossage JR, Hammill A, Heimdal K, Henderson K, Iyer VN, Kjeldsen AD, Komiyama M, Korenblatt K, McDonald J, McMahon J, McWilliams J, Meek ME, Mei-Zahav M, Olitsky S, Palmer S, Pantalone R, Piccirillo JF, Plahn B, Porteous MEM, Post MC, Radovanovic I, Rochon PJ, Rodriguez-Lopez J, Sabba C, Serra M, Shovlin C, Sprecher D, White AJ, Winship I, Zarrabeitia R. Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia. Ann Intern Med. 2020 12 15; 173(12):989-1001.
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Berquist MD, McGill MR, Mazur A, Findley DL, Gorman G, Jones CB, Hambuchen MD. Effect of bile duct ligation-induced liver dysfunction on methamphetamine pharmacokinetics in male and female rats. Drug Alcohol Depend. 2020 10 01; 215:108190.
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He Y, Koch R, Budamagunta V, Zhang P, Zhang X, Khan S, Thummuri D, Ortiz YT, Zhang X, Lv D, Wiegand JS, Li W, Palmer AC, Zheng G, Weinstock DM, Zhou D. DT2216-a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas. J Hematol Oncol. 2020 07 16; 13(1):95.
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Elsawy H, Algefare AI, Alfwuaires M, Khalil M, Elmenshawy OM, Sedky A, Abdel-Moneim AM. Naringin alleviates methotrexate-induced liver injury in male albino rats and enhances its antitumor efficacy in HepG2 cells. Biosci Rep. 2020 06 26; 40(6).
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Mercer KE, Ten Have GAM, Pack L, Lan R, Deutz NEP, Adams SH, Piccolo BD. Net release and uptake of xenometabolites across intestinal, hepatic, muscle, and renal tissue beds in healthy conscious pigs. Am J Physiol Gastrointest Liver Physiol. 2020 08 01; 319(2):G133-G141.
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Lew M, Hissong EM, Westerhoff MA, Lamps LW. Optimizing small liver biopsy specimens: a combined cytopathology and surgical pathology perspective. J Am Soc Cytopathol. 2020 Sep - Oct; 9(5):405-421.
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Smith AK, Ropella GEP, McGill MR, Krishnan P, Dutta L, Kennedy RC, Jaeschke H, Hunt CA. Contrasting model mechanisms of alanine aminotransferase (ALT) release from damaged and necrotic hepatocytes as an example of general biomarker mechanisms. PLoS Comput Biol. 2020 06; 16(6):e1007622.
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Williams AE, Watt J, Robertson LW, Gadupudi G, Osborn ML, Soares MJ, Iqbal K, Pedersen KB, Shankar K, Littleton S, Maimone C, Eti NA, Suva LJ, Ronis MJJ. Skeletal Toxicity of Coplanar Polychlorinated Biphenyl Congener 126 in the Rat Is Aryl Hydrocarbon Receptor Dependent. Toxicol Sci. 2020 05 01; 175(1):113-125.
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James LP, McGill MR, Roberts DW, Hinson JA, Lee WM. Advances in biomarker development in acetaminophen toxicity. Adv Clin Chem. 2020; 98:35-50.
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Davidson CQ, Tharmalingam S, Niccoli S, Nemec-Bakk A, Khurana S, Murray A, Tai TC, Boreham DR, Khaper N, Lees SJ. Dose threshold for radiation induced fetal programming in a mouse model at 4 months of age: Hepatic expression of genes and proteins involved in glucose metabolism and glucose uptake in brown adipose tissue. PLoS One. 2020; 15(4):e0231650.
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de Conti A, Tryndyak V, Willett RA, Borowa-Mazgaj B, Watson A, Patton R, Khare S, Muskhelishvili L, Olson GR, Avigan MI, Cerniglia CE, Ross SA, Sanyal AJ, Beland FA, Rusyn I, Pogribny IP. Characterization of the variability in the extent of nonalcoholic fatty liver induced by a high-fat diet in the genetically diverse Collaborative Cross mouse model. FASEB J. 2020 06; 34(6):7773-7785.
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Fuscoe JC, Vijay V, Hanig JP, Han T, Ren L, Greenhaw JJ, Beger RD, Pence LM, Shi Q. Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism. Drug Metab Dispos. 2020 06; 48(6):447-458.
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Hirahatake KM, Bruno RS, Bolling BW, Blesso C, Alexander LM, Adams SH. Dairy Foods and Dairy Fats: New Perspectives on Pathways Implicated in Cardiometabolic Health. Adv Nutr. 2020 03 01; 11(2):266-279.
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Jones S, Yarbrough AL, Fantegrossi WE, Prather PL, Bush JM, Radominska-Pandya A, Fujiwara R. Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide (STS-135). Pharmacol Res Perspect. 2020 02; 8(1):e00561.
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Vazquez JH, Clemens MM, Allard FD, Yee EU, Kennon-McGill S, Mackintosh SG, Jaeschke H, Hambuchen MD, McGill MR. Identification of Serum Biomarkers to Distinguish Hazardous and Benign Aminotransferase Elevations. Toxicol Sci. 2020 02 01; 173(2):244-254.
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Hernandez GV, Smith VA, Melnyk M, Burd MA, Sprayberry KA, Edwards MS, Peterson DG, Bennet DC, Fanter RK, Columbus DA, Steibel JP, Glanz H, Immoos C, Rice MS, Santiago-Rodriguez TM, Blank J, VanderKelen JJ, Kitts CL, Piccolo BD, La Frano MR, Burrin DG, Maj M, Manjarin R. Dysregulated FXR-FGF19 signaling and choline metabolism are associated with gut dysbiosis and hyperplasia in a novel pig model of pediatric NASH. Am J Physiol Gastrointest Liver Physiol. 2020 03 01; 318(3):G582-G609.
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Coker MS, Ladd KR, Kim J, Murphy CJ, DeCort R, Newcomer BR, Wolfe RR, Coker RH. Essential Amino Acid Supplement Lowers Intrahepatic Lipid despite Excess Alcohol Consumption. Nutrients. 2020 Jan 19; 12(1).
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Zeng H, Larson KJ, Cheng WH, Bukowski MR, Safratowich BD, Liu Z, Hakkak R. Advanced liver steatosis accompanies an increase in hepatic inflammation, colonic, secondary bile acids and Lactobacillaceae/Lachnospiraceae bacteria in C57BL/6 mice fed a high-fat diet. J Nutr Biochem. 2020 04; 78:108336.
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Al-Dwairi A, Brown AR, Pabona JM, Van TH, Hamdan H, Mercado CP, Quick CM, Wight PA, Simmen RC, Simmen FA. Enhanced gastrointestinal expression of cytosolic malic enzyme (ME1) induces intestinal and liver lipogenic gene expression and intestinal cell proliferation in mice. PLoS One. 2014; 9(11):e113058.
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Chappell G, Kobets T, O'Brien B, Tretyakova N, Sangaraju D, Kosyk O, Sexton KG, Bodnar W, Pogribny IP, Rusyn I. Epigenetic events determine tissue-specific toxicity of inhalational exposure to the genotoxic chemical 1,3-butadiene in male C57BL/6J mice. Toxicol Sci. 2014 Dec; 142(2):375-84.
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Hunt CM, Yuen NA, Stirnadel-Farrant HA, Suzuki A. Age-related differences in reporting of drug-associated liver injury: data-mining of WHO Safety Report Database. Regul Toxicol Pharmacol. 2014 Nov; 70(2):519-26.
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Burrow TA, Sun Y, Prada CE, Bailey L, Zhang W, Brewer A, Wu SW, Setchell KDR, Witte D, Cohen MB, Grabowski GA. CNS, lung, and lymph node involvement in Gaucher disease type 3 after 11 years of therapy: clinical, histopathologic, and biochemical findings. Mol Genet Metab. 2015 Feb; 114(2):233-241.
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Uehara T, Pogribny IP, Rusyn I. The DEN and CCl4 -Induced Mouse Model of Fibrosis and Inflammation-Associated Hepatocellular Carcinoma. Curr Protoc Pharmacol. 2014 Sep 02; 66:14.30.1-10.
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Ronis MJ, Miousse IR, Mason AZ, Sharma N, Blackburn ML, Badger TM. Trace element status and zinc homeostasis differ in breast and formula-fed piglets. Exp Biol Med (Maywood). 2015 Jan; 240(1):58-66.
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Shpyleva S, Pogribna M, Cozart C, Bryant MS, Muskhelishvili L, Tryndyak VP, Ross SA, Beland FA, Pogribny IP. Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism. J Nutr Biochem. 2014 Dec; 25(12):1235-42.
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Bohinc BN, Michelotti G, Xie G, Pang H, Suzuki A, Guy CD, Piercy D, Kruger L, Swiderska-Syn M, Machado M, Pereira T, Zavacki AM, Abdelmalek M, Diehl AM. Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism. Endocrinology. 2014 Nov; 155(11):4591-601.
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de Conti A, Tryndyak V, Churchwell MI, Melnyk S, Latendresse JR, Muskhelishvili L, Beland FA, Pogribny IP. Genotoxic, epigenetic, and transcriptomic effects of tamoxifen in mouse liver. Toxicology. 2014 Nov 05; 325:12-20.
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Chirakul S, Bartpho T, Wongsurawat T, Taweechaisupapong S, Karoonutaisiri N, Talaat AM, Wongratanacheewin S, Ernst RK, Sermswan RW. Characterization of BPSS1521 (bprD), a regulator of Burkholderia pseudomallei virulence gene expression in the mouse model. PLoS One. 2014; 9(8):e104313.
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Asakura M, Nakano M, Hayashida K, Fujii H, Nakajima M, Atsuda K, Itoh T, Fujiwara R. Human nitrilase-like protein does not catalyze the hydrolysis of vildagliptin. Drug Metab Pharmacokinet. 2014; 29(6):463-9.
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Lopes PC, Fuhrmann A, Carvalho F, Sereno J, Santos MR, Pereira MJ, Eriksson JW, Reis F, Carvalho E. Cyclosporine A enhances gluconeogenesis while sirolimus impairs insulin signaling in peripheral tissues after 3 weeks of treatment. Biochem Pharmacol. 2014 Sep 01; 91(1):61-73.
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Aissa AF, Tryndyak V, de Conti A, Melnyk S, Gomes TD, Bianchi ML, James SJ, Beland FA, Antunes LM, Pogribny IP. Effect of methionine-deficient and methionine-supplemented diets on the hepatic one-carbon and lipid metabolism in mice. Mol Nutr Food Res. 2014 Jul; 58(7):1502-12.
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Shearn CT, Mercer KE, Orlicky DJ, Hennings L, Smathers-McCullough RL, Stiles BL, Ronis MJ, Petersen DR. Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice. PLoS One. 2014; 9(5):e96553.
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Harrill AH, Eaddy JS, Rose K, Cullen JM, Ramanathan L, Wanaski S, Collins S, Ho Y, Watkins PB, Lecluyse EL. Liver biomarker and in vitro assessment confirm the hepatic origin of aminotransferase elevations lacking histopathological correlate in beagle dogs treated with GABAA receptor antagonist NP260. Toxicol Appl Pharmacol. 2014 Jun 01; 277(2):131-7.
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Huang YW, Hsu CK, Lin SC, Wei SC, Hu JT, Chang HY, Liang CW, Chen DS, Chen PJ, Hsu PN, Yang SS, Kao JH. Reduced toll-like receptor 9 expression on peripheral CD14+ monocytes of chronic hepatitis B patients and its restoration by effective therapy. Antivir Ther. 2014; 19(7):637-43.
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Greer AK, Madadi NR, Bratton SM, Eddy SD, Mazerska Z, Hendrickson HP, Crooks PA, Radominska-Pandya A. Novel resveratrol-based substrates for human hepatic, renal, and intestinal UDP-glucuronosyltransferases. Chem Res Toxicol. 2014 Apr 21; 27(4):536-45.
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Conti Ad, Kobets T, Escudero-Lourdes C, Montgomery B, Tryndyak V, Beland FA, Doerge DR, Pogribny IP. Dose- and time-dependent epigenetic changes in the livers of Fisher 344 rats exposed to furan. Toxicol Sci. 2014 Jun; 139(2):371-80.
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Yang JD, Abdelmalek MF, Pang H, Guy CD, Smith AD, Diehl AM, Suzuki A. Gender and menopause impact severity of fibrosis among patients with nonalcoholic steatohepatitis. Hepatology. 2014 Apr; 59(4):1406-14.
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Lopes PC, Fuhrmann A, Sereno J, Espinoza DO, Pereira MJ, Eriksson JW, Reis F, Carvalho E. Short and long term in vivo effects of Cyclosporine A and Sirolimus on genes and proteins involved in lipid metabolism in Wistar rats. Metabolism. 2014 May; 63(5):702-15.
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Borengasser SJ, Kang P, Faske J, Gomez-Acevedo H, Blackburn ML, Badger TM, Shankar K. High fat diet and in utero exposure to maternal obesity disrupts circadian rhythm and leads to metabolic programming of liver in rat offspring. PLoS One. 2014; 9(1):e84209.
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Compadre CM, Singh A, Thakkar S, Zheng G, Breen PJ, Ghosh S, Kiaei M, Boerma M, Varughese KI, Hauer-Jensen M. Molecular dynamics guided design of tocoflexol: a new radioprotectant tocotrienol with enhanced bioavailability. Drug Dev Res. 2014 Feb; 75(1):10-22.
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Fujiwara R, Itoh T. Extensive protein-protein interactions involving UDP-glucuronosyltransferase (UGT) 2B7 in human liver microsomes. Drug Metab Pharmacokinet. 2014; 29(3):259-65.
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Williams CD, McGill MR, Lebofsky M, Bajt ML, Jaeschke H. Protection against acetaminophen-induced liver injury by allopurinol is dependent on aldehyde oxidase-mediated liver preconditioning. Toxicol Appl Pharmacol. 2014 Feb 01; 274(3):417-24.
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Chappell G, Kutanzi K, Uehara T, Tryndyak V, Hong HH, Hoenerhoff M, Beland FA, Rusyn I, Pogribny IP. Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice. Int J Cancer. 2014 Jun 15; 134(12):2778-88.
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Moylan CA, Pang H, Dellinger A, Suzuki A, Garrett ME, Guy CD, Murphy SK, Ashley-Koch AE, Choi SS, Michelotti GA, Hampton DD, Chen Y, Tillmann HL, Hauser MA, Abdelmalek MF, Diehl AM. Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease. Hepatology. 2014 Feb; 59(2):471-82.
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Kadota Y, Toyoda T, Kitaura Y, Adams SH, Shimomura Y. Regulation of hepatic branched-chain a-ketoacid dehydrogenase complex in rats fed a high-fat diet. Obes Res Clin Pract. 2013 Dec; 7(6):e439-44.
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Casey JM, Banz WJ, Krul ES, Butteiger DN, Goldstein DA, Davis JE. Effect of stearidonic acid-enriched soybean oil on fatty acid profile and metabolic parameters in lean and obese Zucker rats. Lipids Health Dis. 2013 Oct 19; 12:147.
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