 Aspirin
"Aspirin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
| Descriptor ID |
D001241
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| MeSH Number(s) |
D02.455.426.559.389.657.410.595.176
|
| Concept/Terms |
Aspirin- Aspirin
- Acetylsalicylic Acid
- Acid, Acetylsalicylic
- 2-(Acetyloxy)benzoic Acid
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Below are MeSH descriptors whose meaning is more general than "Aspirin".
Below are MeSH descriptors whose meaning is more specific than "Aspirin".
This graph shows the total number of publications written about "Aspirin" by people in UAMS Profiles by year, and whether "Aspirin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 3 | 1 | 4 | | 2017 | 4 | 1 | 5 | | 2016 | 2 | 0 | 2 | | 2015 | 5 | 2 | 7 | | 2014 | 1 | 0 | 1 | | 2013 | 1 | 2 | 3 | | 2012 | 4 | 3 | 7 | | 2011 | 1 | 0 | 1 | | 2010 | 3 | 2 | 5 | | 2009 | 1 | 0 | 1 | | 2008 | 0 | 2 | 2 | | 2007 | 2 | 0 | 2 | | 2006 | 1 | 1 | 2 | | 2005 | 1 | 1 | 2 | | 2004 | 2 | 1 | 3 | | 2003 | 3 | 1 | 4 | | 2002 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 1994 | 1 | 0 | 1 | | 1989 | 0 | 1 | 1 | | 1987 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aspirin" by people in Profiles over the past ten years.
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Iliescu C, Balanescu DV, Donisan T, Giza DE, Muñoz Gonzalez ED, Cilingiroglu M, Song J, Mukerji SS, Lopez-Mattei JC, Kim PY, Palaskas N, Mouhayar EN, Durand JB, Marmagkiolis K. Safety of Diagnostic and Therapeutic Cardiac Catheterization in Cancer Patients With Acute Coronary Syndrome and Chronic Thrombocytopenia. Am J Cardiol. 2018 11 01; 122(9):1465-1470.
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Würtz M, Schmidt M, Grove EL, Horváth-Puhó E, Henderson VW, Christiansen CF, Sørensen HT. Pre-admission use of platelet inhibitors and short-term stroke mortality: a population-based cohort study. Eur Heart J Cardiovasc Pharmacother. 2018 07 01; 4(3):158-165.
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Migally K, Braunlin EA, Zhang L, Binstadt BA. Duration of high-dose aspirin therapy does not affect long-term coronary artery outcomes in Kawasaki disease. Pediatr Res. 2018 06; 83(6):1136-1145.
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Yang X, Leesar MA, Ahmed H, Lendel V, Rodriguez G, Mutlu D, Cawich I, Prasad A, Oglesby M, Marmagkiolis K, Phillips NE, Jouke D, Michalek J, Liu Q, Milner T, McElroy A, Hoyt T, Feldman MD, Cilingiroglu M. Impact of ticagrelor and aspirin versus clopidogrel and aspirin in symptomatic patients with peripheral arterial disease: Thrombus burden assessed by optical coherence tomography. Cardiovasc Revasc Med. 2018 10; 19(7 Pt A):778-784.
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Jacobs V, May HT, Bair TL, Crandall BG, Cutler DO MJ, Day JD, Mallender C, Osborn JS, Weiss JP, Bunch TJ. Long-term aspirin does not lower risk of stroke and increases bleeding risk in low-risk atrial fibrillation ablation patients. J Cardiovasc Electrophysiol. 2017 Nov; 28(11):1241-1246.
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Pandey S, Cottler-Fox M. Acetylsalicylic Acid During Leukapheresis Reduces the Incidence of Clotting in Hematopoietic Progenitor Cell Products. Ann Clin Lab Sci. 2017 Sep; 47(5):551-555.
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Ayyadevara S, Balasubramaniam M, Kakraba S, Alla R, Mehta JL, Shmookler Reis RJ. Aspirin-Mediated Acetylation Protects Against Multiple Neurodegenerative Pathologies by Impeding Protein Aggregation. Antioxid Redox Signal. 2017 Dec 10; 27(17):1383-1396.
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Heath JL, Heath RD, Tamboli C, Johnson L, Wilson AS, Chervinskiy S, Bell MC, Kennedy JL. Mesalamine desensitization in a patient with treatment refractory ulcerative colitis and aspirin and nonsteroidal anti-inflammatory drug hypersensitivity. Ann Allergy Asthma Immunol. 2017 Apr; 118(4):518-520.
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Elbadawi A, Saad M, Nairooz R. Aspirin Use Prior to Coronary Artery Bypass Grafting Surgery: a Systematic Review. Curr Cardiol Rep. 2017 02; 19(2):18.
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Kennedy JL, Stoner AN, Borish L. Aspirin-exacerbated respiratory disease: Prevalence, diagnosis, treatment, and considerations for the future. Am J Rhinol Allergy. 2016 Nov 01; 30(6):407-413.
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Goyal S, Lyzogubov VV, Ali O, Bora PS, Bora NS, Uwaydat SH. Effect of aspirin on models of retinal pigment epithelium pathology. Clin Exp Ophthalmol. 2016 Sep; 44(7):610-617.
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Jain N, Li X, Adams-Huet B, Sarode R, Toto RD, Banerjee S, Hedayati SS. Differences in Whole Blood Platelet Aggregation at Baseline and in Response to Aspirin and Aspirin Plus Clopidogrel in Patients With Versus Without Chronic Kidney Disease. Am J Cardiol. 2016 Feb 15; 117(4):656-663.
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Hoh BL, Gong Y, McDonough CW, Waters MF, Royster AJ, Sheehan TO, Burkley B, Langaee TY, Mocco J, Zuckerman SL, Mummareddy N, Stephens ML, Ingram C, Shaffer CM, Denny JC, Brilliant MH, Kitchner TE, Linneman JG, Roden DM, Johnson JA. CYP2C19 and CES1 polymorphisms and efficacy of clopidogrel and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease. J Neurosurg. 2016 Jun; 124(6):1746-51.
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Nairooz R, Ayoub K, Shavelle D. Duration of Triple Therapy: A Clinical Question Yet to Be Answered. J Am Coll Cardiol. 2015 Nov 17; 66(20):2266.
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Golden LE, Sassoon P, Cáceda R. A case report of late onset psychosis with dementia and aspirin and caffeine addiction. Schizophr Res. 2015 Oct; 168(1-2):591-2.
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Ayoub K, Marji M, Nairooz R. Antithrombotic and Antiplatelet Therapy in Patients Requiring Oral Anticoagulation After Percutaneous Coronary Intervention. Am J Cardiol. 2015 Sep 01; 116(5):828-9.
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Franco AT, Corken A, Ware J. Platelets at the interface of thrombosis, inflammation, and cancer. Blood. 2015 Jul 30; 126(5):582-8.
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Paixao AR, Enriquez JR, Wang TY, Li S, Berry JD, Khera A, Das SR, de Lemos JA, Kontos MC. Risk factor burden and control at the time of admission in patients with acute myocardial infarction: Results from the NCDR. Am Heart J. 2015 Jul; 170(1):173-9, 179.e1.
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Sardar P, Nairooz R, Pekler G. Letter by Sardar et al regarding article, "optimal duration of dual antiplatelet therapy after drug-eluting stent implantation: a randomized, controlled trial". Circulation. 2014 Oct 28; 130(18):e160.
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Wang PY, Chen HP, Chen A, Tsay FW, Lai KH, Kao SS, Chen WC, Kuo CH, Peng NJ, Tseng HH, Hsu PI. Impact of blood type, functional polymorphism (T-1676C) of the COX-1 gene promoter and clinical factors on the development of peptic ulcer during cardiovascular prophylaxis with low-dose aspirin. Biomed Res Int. 2014; 2014:616018.
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Chang J, Ahn JE, Landsman N, Rhee K, Chun L, Patel KK. Efficacy of contemporary medical management for asymptomatic carotid artery stenosis. Am Surg. 2013 Oct; 79(10):987-91.
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Girotra M, Abraham RR, Rabine JC, Dutta SK. Difficult endoscopic hemostasis of post-sphincterotomy bleeding--look beyond aspirin and NSAIDs. Clin Res Hepatol Gastroenterol. 2013 Apr; 37(2):e73-4.
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Kiesz RS, Wiernek SL, Wiernek BK, Radvany MG, Buszman PP, Szymanski R, Konkolewska MD, Martin JL, Buszman PE. Long-term results of plaque excision combined with aggressive pharmacotherapy in high-risk patients with advanced peripheral artery disease (SAVE a LEG registry). Catheter Cardiovasc Interv. 2013 Sep 01; 82(3):E244-50.
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Ayyadevara S, Bharill P, Dandapat A, Hu C, Khaidakov M, Mitra S, Shmookler Reis RJ, Mehta JL. Aspirin inhibits oxidant stress, reduces age-associated functional declines, and extends lifespan of Caenorhabditis elegans. Antioxid Redox Signal. 2013 Feb 10; 18(5):481-90.
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Mitra S, Wang X, Khaidakov M, Ding Z, Ayyadevera S, Hearnsberger E, Goyal T, Mehta JL. Aspirin downregulates angiotensin type 1 receptor transcription implications in capillary formation from endothelial cells. J Cardiovasc Pharmacol. 2012 Aug; 60(2):187-92.
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Bondurant KL, Lundgreen A, Herrick JS, Kadlubar S, Wolff RK, Slattery ML. Interleukin genes and associations with colon and rectal cancer risk and overall survival. Int J Cancer. 2013 Feb 15; 132(4):905-15.
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Bauer ME, Bauer ST, Rabbani AB, Mhyre JM. Peripartum management of dual antiplatelet therapy and neuraxial labor analgesia after bare metal stent insertion for acute myocardial infarction. Anesth Analg. 2012 Sep; 115(3):613-5.
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Khaidakov M, Mitra S, Mehta JL. Adherence junction proteins in angiogenesis: modulation by aspirin and salicylic acid. J Cardiovasc Med (Hagerstown). 2012 Mar; 13(3):187-93.
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Akkus NI, Rajpal S, Agnani S. Successful use of glycoprotein IIb/IIIa inhibitor, heparin, and IABP during PCI in a post-neurosurgical patient with STEMI and cardiogenic shock due to very late bare-metal stent thrombosis. J Invasive Cardiol. 2012 Feb; 24(2):76-8.
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Wang X, Lu J, Khaidakov M, Mitra S, Ding Z, Raina S, Goyal T, Mehta JL. Aspirin suppresses cardiac fibroblast proliferation and collagen formation through downregulation of angiotensin type 1 receptor transcription. Toxicol Appl Pharmacol. 2012 Mar 15; 259(3):346-54.
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Ararat E, Sahin I, Altundag K. Mechanisms behind the aspirin use and decreased breast cancer incidence. J BUON. 2011 Jan-Mar; 16(1):180.
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Khaidakov M, Szwedo J, Mitra S, Ayyadevara S, Dobretsov M, Lu J, Mehta JL. Antiangiogenic and antimitotic effects of aspirin in hypoxia–reoxygenation modulation of the LOX-1-NADPH oxidase axis as a potential mechanism. J Cardiovasc Pharmacol. 2010 Dec; 56(6):635-41.
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Khaidakov M, Szwedo J, Mitra S, Mehta JL. Angiostatic effects of aspirin in hypoxia-reoxygenation are linked to modulation of TGFß1 signaling. J Cardiovasc Pharmacol Ther. 2011 Mar; 16(1):105-10.
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Ararat E, Sahin I, Altundag K. Aspirin intake may prevent metastasis in patients with triple-negative breast cancer. Med Oncol. 2011 Dec; 28(4):1308-10.
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Mehta JL, Bursac Z, Mehta P, Bansal D, Fink L, Marsh J, Sukhija R, Sachdeva R. Racial disparities in prescriptions for cardioprotective drugs and cardiac outcomes in Veterans Affairs Hospitals. Am J Cardiol. 2010 Apr 01; 105(7):1019-23.
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Shakeel M, Trinidade A, McCluney N, Clive B. Complementary and alternative medicine in epistaxis: a point worth considering during the patient's history. Eur J Emerg Med. 2010 Feb; 17(1):17-9.
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