 Amphetamine
"Amphetamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
| Descriptor ID |
D000661
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| MeSH Number(s) |
D02.092.471.683.152.110
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| Concept/Terms |
Amphetamine- Amphetamine
- Phenopromin
- Phenamine
- Amfetamine
- Desoxynorephedrin
Centramina- Centramina
- Miquel Brand of Amfetamine Sulfate
l-Amphetamine- l-Amphetamine
- l Amphetamine
- Levoamphetamine
- levo-Amphetamine
- levo Amphetamine
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Below are MeSH descriptors whose meaning is more general than "Amphetamine".
Below are MeSH descriptors whose meaning is more specific than "Amphetamine".
This graph shows the total number of publications written about "Amphetamine" by people in UAMS Profiles by year, and whether "Amphetamine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2014 | 2 | 0 | 2 | | 2013 | 1 | 0 | 1 | | 2011 | 2 | 1 | 3 | | 2010 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2006 | 1 | 2 | 3 | | 2005 | 3 | 0 | 3 | | 2004 | 2 | 2 | 4 | | 2003 | 1 | 1 | 2 | | 2002 | 0 | 1 | 1 | | 2001 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Amphetamine" by people in Profiles over the past ten years.
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McGill MR, Findley DL, Mazur A, Yee EU, Allard FD, Powers A, Coward L, Blough ER, Gorman G, Hambuchen MD. Radiation Effects on Methamphetamine Pharmacokinetics and Pharmacodynamics in Rats. Eur J Drug Metab Pharmacokinet. 2022 May; 47(3):319-330.
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Freyberg Z, Sonders MS, Aguilar JI, Hiranita T, Karam CS, Flores J, Pizzo AB, Zhang Y, Farino ZJ, Chen A, Martin CA, Kopajtic TA, Fei H, Hu G, Lin YY, Mosharov EV, McCabe BD, Freyberg R, Wimalasena K, Hsin LW, Sames D, Krantz DE, Katz JL, Sulzer D, Javitch JA. Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain. Nat Commun. 2016 Feb 16; 7:10652.
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White SJ, Hendrickson HP, Atchley WT, Laurenzana EM, Gentry WB, Williams DK, Owens SM. Treatment with a monoclonal antibody against methamphetamine and amphetamine reduces maternal and fetal rat brain concentrations in late pregnancy. Drug Metab Dispos. 2014 Aug; 42(8):1285-91.
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Thakkar S, Nanaware-Kharade N, Celikel R, Peterson EC, Varughese KI. Affinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering. Sci Rep. 2014 Jan 14; 4:3673.
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Levi MS, Patton RE, Hanig JP, Tranter KM, George NI, James LP, Davis KJ, Bowyer JF. Serum myoglobin, but not lipopolysaccharides, is predictive of AMPH-induced striatal neurotoxicity. Neurotoxicology. 2013 Jul; 37:40-50.
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